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A qualitative study on the pulsatile flow phenomenon in a dense fly ash pneumatic conveyor

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Particuology 2014年第6期12卷 81-91页

作者： Wei Chen kenneth C.Williams Isabel jabs Mark G.jones Centre for Bulk Solids and Particulate Technologies Newcastle Institute for Energy and ResourcesThe University of Newcastle Faculty of Mechanical Engineering Leibniz University of Hanover

Understanding of the dynamic particulate flow structures within a dense gas-fly ash pneumatic conveyor must be improved in order to better aid its design *** complex pulsatile movement of the gas-fly ash mixture dominates the flow performance within the pipeline,and historically,non-invasive measurement devices such as the electrical capacitance tomography（ECT） were often used to sufficiently capture the flow ***,inadequate studies have been conducted on the pulsatile flow phenomenon,which directly relate to the gas-fly ash two-phase flow *** paper aims to investigate the pulsatile flows using an ECT ***,pulsatile flow patterns under various experimental conditions were obtained through *** within a flow were then characterised into pulse growth and decay segments,which represent the superficial fluidisation and deaeration processes during ***,structural and statistical analyses were performed on the pulse growth and decay *** suggested that the increasing air mass flow rate led to the decrease of the superficial fluidisation/deaeration magnitude,however,the increase of the superficial fluidisation/deaeration ***,the air mass flow rate was indicated as the dominant factor in determining the pulsing statistical *** research provides fundamental insights for further modelling the dense fly ash pneumatic flows.

关键词： Pneumatic conveying Electrical capacitance tomography Fly ash Pulsatile flows Flow pattern analysis

Patient prompting of their physician resulted in increased colon cancer screening referrals

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World journal of Gastrointestinal Oncology 2014年第7期6卷 257-262页

作者： Vu Le Saqib Syed kenneth j Vega Tushar Sharma Mohammad F Madhoun Nakumar Srinivasan Courtney W Houchen Division of Digestive Disease and Nutrition Univer-sity of Oklahoma Health Sciences Center Oklahoma City OK 73104 United States College of Public Health University of Okla-homa Health Sciences Center Oklahoma City OK 73104 United States

AIM:To determine whether a communication instru-ment provided to patients prior to their primary carephysician(PCP)visit initiates a conversation with theirPCP about colorectal cancer screening(CRC-S),impact-ing screening referral rates in fully insured and underin-sured ***:A prospective randomized control studywas performed at a single academic center outpatient internal medicine(IRMC,underinsured)and fam-ily medicine(FMRC,insured)resident clinics prior to scheduled *** the intervention group,a pamphlet about the benefit of CRC-S and a reminder card were given to patients before the scheduled visit for prompt-ing of CRC-S referral by their *** main outcome measured was frequency of CRC-S referral in each clinic after ***:In the IRMC,148 patients participated,a control group of 72 patients(40F and 32M)and 76 patients(48F and 28M)in the intervention ***-ferrals for CRC-S occurred in 45/72(63%)of control vs 70/76(92%)in the intervention group(P≤0.001).In the FMRC,126 patients participated,66(39F:27M)con-trol and 60(33F:27M)in the intervention ***-S referrals occurred in 47/66(71%)of controls vs 56/60(98%)in the intervention group(P≤0.001).CONCLUSION:Patient initiated physician prompting produced a significant referral increase for CRC-S in un-derinsured and insured patient *** investigation aimed at increasing CRC-S acceptance is warranted.

关键词： Colon cancer Screening Primary care Physician patient relationship Referral

Biophotoelectrochemistry:An emerging frontier for channeling photoelectric effect into darkness zone of soils and sediments

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Pedosphere 2024年第1期34卷 5-8页

作者： jie YE Shungui ZHOU kenneth H.NEALSON Christopher RENSING Fujian Provincial Key Laboratory of Soil Environmental Health and Regulation College of Resources and EnvironmentFujian Agriculture and Forestry UniversityFuzhou 350002China Department of Earth Science University of Southern CaliforniaLos Angeles CA 90007USA

Solar energy captured by photosynthetic plants in the photic zone is recognized as the main driver for the formation of organic matter utilized by soil communities. However, the contribution of organic transformation to the linkage of solar energy and microbial metabolism of soils is reduced when the vadose zone is saturated. In contrast to the conventional biophotoelectrochemistry via photosynthesis with phytoplankton during the periodic saturation of soils, recent studies suggest that non-phototrophic microorganisms in soils and sediments are able to conduct light-dependent metabolism to sustain their functionality with photosensitizers under illumination. These interactions and processes utilize long-distance electron transfer networks to interconnect diverse electron transfer chains that channel photoexcited electrons into the opaque zone for soil communities. Such an emerging process not only allows for a better understanding of biogeochemical processes such as soil carbon sequestration and mitigation, but also shows great potential for environmental treatment such as the bioremediation of contaminated soils. Therefore, we suggest that biophotoelectrochemistry via photoelectric effect can have significant, heretofore unappreciated, theoretical and practical values.

关键词： soils soil metabolism

Progress in Machine Translation

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Engineering 2022年第11期18卷 143-153页

作者： Haifeng Wang Hua Wu Zhongjun He Liang Huang kenneth Ward Church Baidu Inc. Beijing 100193China Baidu Research SunnyvaleCA 94089USA

After more than 70 years of evolution,great achievements have been made in machine *** in recent years,translation quality has been greatly improved with the emergence of neural machine translation(NMT).In this article,we first review the history of machine translation from rule-based machine translation to example-based machine translation and statistical machine *** then introduce NMT in more detail,including the basic framework and the current dominant framework,Transformer,as well as multilingual translation models to deal with the data sparseness *** addition,we introduce cutting-edge simultaneous translation methods that achieve a balance between translation quality and *** then describe various products and applications of machine *** the end of this article,we briefly discuss challenges and future research directions in this field.

关键词： Machine translation Neural machine translation Simultaneous translation

Evolution of endovascular mechanical thrombectomy for acute ischemic stroke

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World journal of Clinical Cases 2014年第11期2卷 614-622页

作者： Colin j Przybylowski Dale Ding Robert M Starke Christopher R Durst R Webster Crowley kenneth C Liu Department of Neurological Surgery University of VirginiaCharlottesvilleVA 22908United States Department of Radiology and Medical Imaging University of Virginia Charlottesville VA 22908 United States

Acute ischemic stroke(AIS) is a common medical problem associated with significant morbidity and mortality worldwide. A small proportion of AIS patients meet eligibility criteria for intravenous thrombolysis(IVT) with recombinant tissue plasminogen activator, and its efficacy for large vessel occlusion is poor. Therefore, an increasing number of patients with AIS are being treated with endovascular mechanical thrombectomy when IVT is ineffective or contraindicated. Rapid advancement in catheter-based and endovascular device technology has led to significant improvements in rates of cerebral reperfusion with these devices. Stentrievers and modern aspiration catheters have now surpassed earlier generation devices in the degree and rapidity of revascularization. This progress has been achieved with no concurrent increase in risk of major complications or mortality, both when used alone or in combination with IVT. The initial randomized controlled trials comparing endovascular therapy to IVT for AIS failed to show superior outcomes with endovascular treatment, butkey limitations of each trial may limit the significance of these results to current practice. While endovascular devices and operator experience continue to evolve, we are optimistic that this will be accompanied by improvements in patient outcomes. This review highlights the major endovascular devices used in current practice and the trials which have investigated their efficacy.

关键词： Cerebral infarction Endovascular procedures Intracranial hemorrhages Stents Stroke

A Large Therizinosauroid(Dinosauria:Theropoda) from the Early Cretaceous of Northwestern China

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Acta Geologica Sinica(English Edition) 2007年第4期81卷 539-549页

作者： LI Daqing PENG Cuo YOU Hailu Matthew C. LAMANNA jerald D. HARRIS kenneth j. LACOVARA ZHANG jianping China University of Geosciences School of Earth Sciences and Resources Beijing 100083 P. R. China Fossil Research and Development Center of the Third Geology and Mineral Resources Exploration Academy of Gansu Province Lanzhou Gansu Province 730050 P. R. China Institute of Geology Chinese Academy of Geological Sciences Beijing 100037 P. R. China Section of Vertebrate Paleontology Carnegie Museum of Natural History Pittsburgh Pennsylvania 15213 USA Dixie State College Science Building Utah 84770 USA Paleontology and Geology Program Department of Bioscience and Biotechnology Drexel University Philadelphia Pennsylvania 19104 USA

We herein describe an associated partial postcranial skeleton of a theropod dinosaur discovered in the Lower Cretaceous Xinminpu Group of the Yujingzi Basin, in the jiuquan area of Gausu Province, northwestern China. Features of its humerus, such as strongly expanded proximal and distal ends, a well developed medial tuberosity, distal condyles expressed on the humeral cranial surface, and a hypertrophied entepicondyle, definitively establish the therizinosauroid affinities of the specimen. It differs from other therizinosauroids in having a shallow, poorly demarcated glenoid fossa with a prominent rounded and striated tumescence on the dorsomedial surface of its scapular portion, and a pubis with a strongly concave cranial margin. It represents a new taxon, Suzhousaurus megatherioides gen. et sp. nov. Cladistic analysis recovers Suzhousaurus as the sister taxon of Nothronychus mckinleyi from the mid-Cretaceous of western North America; together, they are basal members of the Therizinosauroidea, more derived than the Early Cretaceous Falcarius and Beipiaosaurus but less derived than Alxasaurus and the Therizinosauridae. Along with ＂Nanshiungosaurus＂ bohlini from possibly coeval beds in the Mazongshan area of northern-most Gansu, Suzhousaurus represents one of the largest-known Early Cretaceous therizinosauroids, demonstrating that this clade attained considerable body size early in its evolutionary history.

关键词： Dinosauria Theropoda Therizinosauroidea Yujingzi Basin Early Cretaceous jiuquan area Gansu Province China

Pefabloc- A sulfonyl fluoride serine protease inhibitor blocks induction of Diotericin in Drosoohila 1（2）mbn cells

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Insect Science 2012年第4期19卷 472-476页

作者： Karin C. johansson kenneth Soderhall Maria I. Lind Department of Comparative Physiology Evolutionary Biology Centre Uppsala University Uppsala Sweden

Insects protect themselves against microbial infection by an efficient innate immune system that is activated by recognition ofinvariant microbial surface molecules. In the fruit fly Drosophila melanogaster the presence of bacteria is associated with expression of antimicrobial peptides in host immune-competent tissues. Host receptors detect infection and relay the signal to mount the appropriate immune response. In Drosophila hemocyte- like l（2）mbn cells pre-infection treatment with Pefabloc, a commonly used serine protease inhibitor, induced two major effects： it blocked expression of the antibacterial peptide Diptericin in response to live Gram-negative bacteria and bacterial surface molecules （crude lipopolysaccharide contaminated by peptidoglycans） and it induced morphological changes.

关键词： cell morphology diptericin Drosophila IMD pathway immune response,proteinase inhibitor

胶东区域成矿断裂带蚀变年龄研究及其矿床学意义

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地学前缘 2017年第2期24卷 140-150页

作者：吕承训 Norbert H.MAERZ kenneth j.BOYKO 吕古贤邵鹤森密苏里科技大学地质科学与石油及地质工程学院美国密苏里州罗拉65401 中国地质科学院地质力学研究所北京100081 中国地质大学(北京)地球科学与资源学院北京100083

胶东金矿是中生代构造岩浆活化区岩浆期后中温热液蚀变脉状矿床。前人曾认为该类金矿属于壳源深融花岗岩-热液石英脉-蚀变岩型金矿。近期研究表明,胶东金矿围岩蚀变年龄的测定,对于矿床成因的研究有重要意义。为解决胶东区域断裂热液蚀... 详细信息

胶东金矿是中生代构造岩浆活化区岩浆期后中温热液蚀变脉状矿床。前人曾认为该类金矿属于壳源深融花岗岩-热液石英脉-蚀变岩型金矿。近期研究表明,胶东金矿围岩蚀变年龄的测定,对于矿床成因的研究有重要意义。为解决胶东区域断裂热液蚀变年龄问题,对胶东半岛主要断裂矿化蚀变带开展如下相关研究:(1)选择胶东地区各蚀变岩带普遍发育的黄铁绢英岩化蚀变岩带和强钾长石化蚀变岩带作为取样目标,进行区域对比;(2)该两类岩石中的蚀变矿物受到脆性断裂影响较小,能够得到蚀变阶段的稳定化学成分;(3)该两类岩石中的蚀变矿物发育有与蚀变同期的韧性变形,能够揭示蚀变阶段的构造应力应变状态。对样品中的钾长石和斜长石颗粒进行K-Ar法同位素年龄测试,获得蚀变岩同位素年龄数据。测试结果显示,胶东区域构造热液蚀变作用时期为(148.3±4.3)^(52.03±0.70)Ma,即早白垩世燕山晚期;同位素年龄自西向东逐渐变小,证明胶东西部地区的热液蚀变作用早于东部地区。通过分析已有的构造、热液成分和成矿物理化学参数等资料,结合本研究的最新成果,总结出区域成矿时代与成矿规律:胶东区域断裂蚀变系统中的构造附加静水压力、流体温度压力条件和成矿元素的分布与变化控制了热液蚀变成矿规律。上述地质特征显示,胶东金矿床是复成构造热液作用下的一种新型矿床类型。

关键词：胶东金矿 K-Ar同位素年龄黄铁绢英质蚀变岩带钾长石化蚀变岩带复成构造热液作用

Tsc2 mutation induces renal tubular cell nonautonomous disease

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Genes & Diseases 2022年第1期9卷 187-200页

作者： Prashant Kumar Fahad Zadjali Ying Yao Daniel johnson Brian Siroky Aristotelis Astrinidis Peter Vogel kenneth W.Gross john j.Bissler Department of Pediatrics University of Tennessee Health Science Center and Le Bonheur Children's HospitalMemphisTN 38103USA Children's Foundation Research Institute(CFRI) Le Bonheur Children's HospitalMemphisTN 38105USA Department of Clinical Biochemistry College of Medicine&Health SciencesSultan Qaboos UniversityMuscat 123Oman Molecular Bioinformatics Center University of Tennessee Health Science CenterMemphisTN 38163USA Department of Veterinary Pathology St.Jude Children's Research HospitalMemphisTN 38105USA Department of Molecular and Cellular Biology Roswell Park Comprehensive Cancer CenterBuffaloNY 14263USA Pediatric Medicine Department St.Jude Children's Research HospitalMemphisTN 38105USA

TSC renal cystic disease is poorly understood and has no approved *** a new principal cell-targeted murine model of Tsc cystic disease,the renal cystic epithelium is mostly composed of type A intercalated cells with an intact Tsc2 gene confirmed by sequencing,although these cells exhibit a Tsc-mutant disease *** used a newly derived targeted murine model in lineage tracing and extracellular vesicle(EV)characterization experiments and a cell culture model in EV characterization and cellular induction experiments to understand TSC *** lineage tracing experiments,we found principal cells undergo clonal expansion but contribute very few cells to the *** determined that cystic kidneys contain more interstitial EVs than noncystic kidneys,excrete fewer EVs in urine,and contain EVs in cyst ***,the loss of Tsc2 gene in EV-producing cells greatly changes the effect of EVs on renal tubular epithelium,such that the epithelium develops increased secretory and proliferative pathway *** demonstate that the mTORC1 pathway activity is independent form the EV production,and that the EV effects for a single cell line can vary *** cystogenesis involves significant contribution from genetically intact cells conscripted to the mutant phenotype by mutant cell derived EVs.

关键词： Cell nonautonomous trait Polycystic kidney disease Renalcystogenesis Tuberous sclerosis complex