检索结果-南通市图书馆

Assistive technologies and habit development:a semiotic Model of Technological Mediation

在线全文

学校读者我要写书评

暂无评论

Language and semiotic studies 2024年第1期10卷 43-64页

作者： Bent sørensen Martin Thellefsen Torkild Thellefsen Independent scholar AalborgDenmark Department of Communication Copenhagen UniversityCopenhagenDenmark Independent scholar Nr.SundbyDenmark

In the field of philosophy of technology,the concept of mediation is central to understanding how technology shapes human experience and *** aim in this paper is to contribute to the understanding of technological mediation,in particular how and why it is *** mediation occurs within a mediation space between the technological realm and the user *** the technological realm,technology regularizes events and actions,while in the user realm,the user interprets the significative potential of the *** interpretation process is identical with use and involves the formation of user habits,which are constrained by technological,cognitive,and sociocultural *** provide a theoretical framework for our analysis,we propose the semiotic Model of Technological Mediation(sMTM),which draws on Charles Peirceʼs *** illustrate our argument,we focus on assistive technology and provide a recurring example of the Medimi®smart,a digital,comprehensive system for medication handling.

关键词： philosophy of technological mediation assistive technology Charles Peirceʼs semiotics habit formation and user technology relation semiotic Model of Technological Mediation

Decoding the Molecular Mechanisms of BRAFV600E-Induced Nevi Formation

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Biomedical and Environmental sciences 2024年第7期37卷 774-784页

作者： Weizheng Liang Yuxuan Liu Dandan Xu Wenjie Jiang rensen Ran Central Laboratory The First Affiliated Hospital of Hebei North UniversityZhangjiakou 075000HebeiChina Institute of Molecular Immunology School of Laboratory Medicine and BiotechnologySouthern Medical UniversityGuangzhou 510515GuangdongChina Department of Artificial Intelligence and Data science Hebei University of TechnologyTianjin 300401China Department of Chemical Biology School of Life SciencesSouthern University of Science and TechnologyShenzhen 518055GuangdongChina

Melanocytes derived from neural crest cells harbor the BRAFV600E mutation,which is the predominant driver of nevus formation in *** mutation leads to malignant cell proliferation and subsequent cell cycle arrest,culminating in oncogene-induced senescence and nevus ***,emerging evidence has highlighted the heterogeneity of cellular senescence markers in BRAFV600E-induced senescent ***,the capacity of melanocytes within nevi to regain their proliferative ability raises questions about the molecular mechanisms by which BRAFV600E,via the mitogen-activated protein kinase signaling pathway,triggers nevus *** study provides an overview and discussion of the molecular mechanisms underpinning BRAFV600E-induced melanocyte nevus formation and the relevant animal models employed for their *** also highlights the significance of elucidating dynamic changes in cytoplasmic and nuclear substrates that interact with phosphorylated extracellular signal-regulated protein kinases 1 and 2 and underscores the value of using targeted BRAFV600E animal models created through gene editing technologies.

关键词： BRAFV600E Melanocytes Nevi Oncogene-induced senescence Animal models

Well-Posedness of stochastic Continuity Equations on Riemannian Manifolds

在线全文

学校读者我要写书评

暂无评论

Chinese Annals of Mathematics,series B 2024年第1期45卷 81-122页

作者： Luca GALIMBERTI kenneth H.KARLsEN Department of Mathematical sciences NTNU Norwegian University of Science and TechnologyN-7491 TrondheimNorway Department of mathematics University of OsloP.O.Box 1053BlindernN-0316 OsloNorway

The authors analyze continuity equations with stratonovich stochasticity,■ρ+divh[ρo(u(t,x)+∑_(i=1)^(N)a_(i)(x)w_(i)(t))]=0defined on a smooth closed Riemannian manifold M with metric *** velocity field u is perturbed by Gaussian noise terms Wi(t),:WN(t)driven by smooth spatially dependent vector fields a1(x),...,aN(x)on *** velocity u belongs to L_(t)^(1)W_(x)^(1,2)with divh u bounded in Lf,for p>d+2,where d is the dimension of M(they do not assume div_(h) u∈L_(t,x)^(∞)).For carefully chosen noise vector fields ai(and the number N of them),they show that the initial-value problem is well-posed in the class of weak L^(2) solutions,although the problem can be ill-posed in the deterministic case because of concentration *** proof of this“regularization by noise”result is based on a L^(2) estimate,which is obtained by a duality method,and a weak compactness argument.

关键词： stochastic continuity equation Riemannian manifold Hyperbolic equa-tion Non-smooth velocity field Weak solution Existence Uniqueness

surgical cystogastrostomy: Is it still worthwhile?

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第17期30卷 2298-2301页

作者： Kin Pan Au kenneth siu Ho Chok Department of surgery Queen Mary HospitalThe University of Hong KongHong Kong 999077China Department of surgery The Chinese University of Hong KongHong Kong 999077China

The article by Ker et al explores the treatment of peripancreatic fluid collection(PFC).The use of percutaneous drainage,endoscopy,and surgery for managing PFC are *** drainage is noted for its low risk profile,while endoscopic cystogastrostomy is more effective due to the wider orifice of the metallic *** cystogastrostomy is a definitive treatment with a reduced need for reintervention,especially for cases with extensive collections and significant *** choice of treatment modality should be tailored to individual patient characteristics and disease factors,considering the expertise available.

关键词： Endoscopic cystgastrostomy surgical cystgastrostomy Pancreatitis Pancreatic necrosis Peripancreatic collection

Biophotoelectrochemistry:An emerging frontier for channeling photoelectric effect into darkness zone of soils and sediments

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pedosphere 2024年第1期34卷 5-8页

作者： Jie YE shungui ZHOU kenneth H.NEALsON Christopher RENsING Fujian Provincial Key Laboratory of soil Environmental Health and Regulation College of Resources and EnvironmentFujian Agriculture and Forestry UniversityFuzhou 350002China Department of Earth science University of Southern CaliforniaLos Angeles CA 90007USA

solar energy captured by photosynthetic plants in the photic zone is recognized as the main driver for the formation of organic matter utilized by soil communities. However, the contribution of organic transformation to the linkage of solar energy and microbial metabolism of soils is reduced when the vadose zone is saturated. In contrast to the conventional biophotoelectrochemistry via photosynthesis with phytoplankton during the periodic saturation of soils, recent studies suggest that non-phototrophic microorganisms in soils and sediments are able to conduct light-dependent metabolism to sustain their functionality with photosensitizers under illumination. These interactions and processes utilize long-distance electron transfer networks to interconnect diverse electron transfer chains that channel photoexcited electrons into the opaque zone for soil communities. such an emerging process not only allows for a better understanding of biogeochemical processes such as soil carbon sequestration and mitigation, but also shows great potential for environmental treatment such as the bioremediation of contaminated soils. Therefore, we suggest that biophotoelectrochemistry via photoelectric effect can have significant, heretofore unappreciated, theoretical and practical values.

关键词： soils soil metabolism

Bile acid signaling in the regulation of whole body metabolic and immunological homeostasis

在线全文

学校读者我要写书评

暂无评论

science China(Life sciences) 2024年第5期67卷 865-878页

作者： Wei Jia Yitao Li kenneth C.P.Cheung Xiaojiao Zheng school of Chinese Medicine Hong Kong Baptist UniversityHong KongChina Center for Translational Medicine and shanghai Key Laboratory of Diabetes Mellitus Shanghai Sixth People's Hospital Affiliated to Shanghai JiaoTong University School of MedicineShanghai 200233China

Bile acids(BAs)play a crucial role in nutrient absorption and act as key regulators of lipid and glucose metabolism and immune *** the enterohepatic circulation,BAs are synthesized,metabolized,and reabsorbed,with a portion entering the vascular circulation and distributing *** allows BAs to interact with receptors in all major organs,leading to organ-organ interactions that regulate both local and global metabolic processes,as well as the immune *** review focuses on the whole-body effects of BA-mediated metabolic and immunological regulation,including in the brain,heart,liver,intestine,eyes,skin,adipose tissue,and *** BA synthesis and receptor signaling is a promising strategy for the development of novel therapies for various diseases throughout the body.

关键词： bile acid whole body metabolism immunity

Mechanistic insight into Cr(Ⅵ)retention by si-containing ferrihydrite

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental sciences 2024年第5期139卷 217-225页

作者： Ying Hu Qiang Xue Honghan Chen Huaming Guo kenneth C.Carroll song Wang MOE Key Laboratory of Groundwater Circulation and Environmental Evolution School of Water Resources and EnvironmentChina University of Geosciences(Beijing)Beijing 100083China Beijing Key Laboratory of Water Resources and Environmental Engineering School of Water Resources and EnvironmentChina University of GeosciencesBeijing 100083China state Key Laboratory of Biogeology and Environmental Geology China University of GeosciencesBeijing 100083China Plant&Environmental science New Mexico State UniversityNM 88003USA Institute of Theoretical Chemistry College of ChemistryJilin UniversityChangchun 130023China

Hexavalent chromium[Cr(Ⅵ)]causes serious harm to the environment due to its high toxicity,solubility,and ***(Fh)are the main adsorbent and trapping agent of Cr(Ⅵ)in soils and aquifers,and they usually coexist with silicate(si),forming si-containing ferrihydrite(si-Fh)***,the mechanism of Cr(Ⅵ)retention by si-Fh mixtures is poorly *** this study,the behaviors and mechanisms of Cr(Ⅵ)adsorption onto si-Fh with different si/Fe molar ratios was *** electron microscope,Fourier transform infrared spectroscopy,X-ray diffraction,X-ray photoelectron spectroscopy,and other techniques were used to characterize si-Fh and Cr(Ⅵ)-loading of *** results show that specific surface area of si-Fh increases gradually with increasing si/Fe ratios,but Cr(Ⅵ)adsorption on si-Fh decreases with increasing si/Fe *** is because with an increase in si/Fe molar ratio,the point of zero charge of si-Fh gradually decreases and electrostatic repulsion between si-Fh and Cr(Ⅵ)***,the complexation of Cr(Ⅵ)is enhanced due to the increase in adsorbed hydroxyl(A-OH-)on si-Fh with increasing si/Fe molar ratio,which partly counteracts the effect of the electrostatic ***,the increase in the electrostatic repulsion has a greater impact on adsorption than the additional complexation with *** functional theory calculation further supports this observation,showing the increases in electron variation of bonding atoms and reaction energies of inner spherical complexes with the increase in si/Fe ratio.

关键词： Hexavalent chromium Ferrihydrite si/Fe ratio Cr(Ⅵ)Adsorption

smart mid-infrared metasurface microspectrometer gas sensing system

在线全文

学校读者我要写书评

暂无评论

Microsystems & Nanoengineering 2024年第3期10卷 273-281页

作者： Jiajun Meng sivacarendran Balendhran Ylias sabri suresh K.Bhargava kenneth B.Crozier school of Physics University of MelbourneVictoriaAustralia Australian Research Council(ARC)Centre of Excellence for Transformative Meta-Optical systems(TMOs) University of MelbourneVictoriaAustralia Centre for Advanced Materials&Industrial Chemistry(CAMIC) STEM collegeRMIT UniversityVictoriaAustralia Department of Electrical and Electronic Engineering University of MelbourneVictoriaAustralia

smart,low-cost and portable gas sensors are highly desired due to the importance of air quality monitoring for environmental and defense-related ***,electrochemical and nondispersive infrared(IR)gas sensors are designed to detect a single specific *** IR spectroscopy-based sensors provide superior performance,their deployment is limited due to their large size and high *** this study,a smart,low-cost,multigas sensing system is demonstrated consisting of a mid-infrared microspectrometer and a machine learning *** microspectrometer is a metasurface filter array integrated with a commercial IR camera that is consumable-free,compact(~1 cm^(3))and lightweight(~1 g).The machine learning algorithm is trained to analyze the data from the microspectrometer and predict the gases *** system detects the greenhouse gases carbon dioxide and methane at concentrations ranging from 10 to 100%with 100%*** also detects hazardous gases at low concentrations with an accuracy of 98.4%.Ammonia can be detected at a concentration of 100 ***,methyl-ethyl-ketone can be detected at its permissible exposure limit(200 ppm);this concentration is considered low and *** study demonstrates the viability of using machine learning with IR spectroscopy to provide a smart and low-cost multigas sensing platform.

关键词： smart gases system

Introducing the Hong Kong Medical Journal and its important role in the timely dissemination of COVID-19 related knowledge

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2024年第3期137卷 253-254页

作者： Rashid N Lui kenneth KW Li Martin Cs Wong Hong Kong Medical Journal Hong Kong SARChina The JC school of Public Health and Primary Care Faculty of MedicineThe Chinese University of Hong KongHong Kong SARChina

Hong Kong Medical Journal(HKMJ)is the flagship general medical journal in the Hong Kong special Administrative Region,China,with an international *** are committed to publishing and promoting high-quality *** by our Editor-in-Chief,Professor Martin Cs Wong,our Editorial Board is pleased to collaborate with *** Wang,the Editor-in-Chief of the Chinese Medical Journal(CMJ),as well as the editors of CMJ to enhance the visibility of our respective journals and foster a collaborate environment that brings forth ideas and knowledge to our readers.

关键词： journal knowledge visibility