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国外畜牧学(猪与禽) 1988年第4期 29-33页

作者： R. d. A. Cameron 朱久明澳大利亚昆士兰大学兽医系

引言影响养猪效益的一个最重要的因素是,每头母猪年产多少活的、健康的,并能存活的仔猪。尽管母猪对受胎率和产仔数影响相当大(kennedy和Moxley,1978),但是公猪效应也不可忽视。根

关键词：公猪月龄初情期精子发生采精精子数量精液品质

Voxel Placement Precision for GABA-Edited Magnetic Resonance Spectroscopy

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Open Journal of Radiology 2017年第1期7卷 35-44页

作者： Xue Bai Ashley d.Harris Tao Gong Nicolaas A.J.Puts Guangbin Wang Michael Schar Peter B.Barker Richard A.E.Edden department of Radiology Qilu Hospital of Shandong UniversityJinanChina Russell H.Morgan department of Radiology and Radiological Science The Johns Hopkins University School of MedicineBaltimoreMDUSA F.M.Kirby Research Center for Functional Brain Imaging Kennedy Krieger InstituteBaltimoreMDUSA department of MR Shandong Medical Imaging Research InstituteShandong UniversityJinanChina

The purpose of the present study was to assess the reproducibility of voxel placement for GABA-edited MRS. GABA-edited MRS data were acquired in 13 healthy volunteers from (3 cm)3 voxel;and within the same session a second acquisition was independently prescribed. A three-dimensional voxel mask image was reconstructed in T1-image-space using the SVMask tool (in house software). Reproducibility of voxel placement was assessed using the dice overlap coefficient, both within-subject and between-subject following co-registration of T1 images and transformation of voxel mask images to standard space. Within-subject overlap coefficients were 86% ± 5%. Between-subject overlap coefficients were 75% ± 10%. For the two voxel locations considered (occipital and sensorimotor), voxel overlap was very similar. Between-subject values are higher due to between-session effects, anatomical variability and volume mismatch in standard space. While surprisingly low in terms of volume overlap, the overlap coefficients correspond to acceptable linear displacements.

关键词： MRS Voxel Placement Precision Voxel Prescription Registration

在人类表型本体论中对癫痫发作进行建模——根据当代ILAE概念使大的表型数据易于处理

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癫痫杂志 2022年第5期8卷 457-468页

作者： david Lewis-Smith Peter d Galer Ganna Balagura 黄格格(译) 牛永利(译) 杨建仲(审) 不详

癫痫的临床特征决定了如何定义癫痫,进而指导治疗。因此,在对癫痫病因、轨迹和治疗反应的研究中,考虑构成癫痫的基本临床实体至关重要。人类表型本体论(Human phenotype ontology,HPO)广泛应用于临床和遗传学研究中用于临床特征的简明... 详细信息

癫痫的临床特征决定了如何定义癫痫,进而指导治疗。因此,在对癫痫病因、轨迹和治疗反应的研究中,考虑构成癫痫的基本临床实体至关重要。人类表型本体论(Human phenotype ontology,HPO)广泛应用于临床和遗传学研究中用于临床特征的简明交流和建模,其允许使用逻辑推理来协调提取的数据。我们试图重新设计HPO癫痫亚本体,以提高其与当前癫痫概念的一致性,同时支持在高通量临床和基因组研究中应用大型临床数据集。根据2017年国际抗癫痫联盟对癫痫发作类型的分类,我们创建了一个新的HPO癫痫亚本体,并在不同细节层次上整合了癫痫持续状态、热性惊厥、反射性发作和新生儿癫痫的概念。我们比较了修订前后的HPO癫痫亚本体,根据3个独立队列中791例患者的癫痫发作信息可以推断:其中2个独立队列的信息先前已发表过,还有150例患者是新招募的。每个队列的数据以不同的格式提供,并通过两个版本的HPO进行协调。新的癫痫亚本体将癫痫发作的描述性概念数量增加了5倍。可标注到队列中的癫痫发作描述符号数量增加了40%,关于个体癫痫发作的信息总量增加了38%。最重要的定性差异是局灶性进展为双侧强直-阵挛发作与全面起始和局灶起始发作的关系。我们已经生成了一个详细的当代概念图,用于协调临床癫痫发作数据,并在2020-12-07 HPO的官方版本中实施,并在***免费提供。这将有助于克服基因组学中的表型瓶颈,促进有价值数据的再利用,并最终提高对癫痫的诊断和精准治疗。

关键词：大数据分类癫痫遗传学

Incidenee and time-varying predictors of HIV and sexually transmitted infections among male sex workers in Mexico City

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Infectious diseases of Poverty 2021年第1期10卷 36-45页

作者： Karla Y.Ganley Marta Wilson-Barthes Andrew R.Zullo Sandra G.Sosa-Rubi Carlos J.Conde-Glez Santa Garcia-Cisneros Mark N.Lurie Brandon d.L.Marshall don Operario Kenneth H.Mayer Omar Galarraga department of Narrative Medicine Columbia UniversityNew YorkNYUSA department of Epidemiology School of Public HealthBrown UniversityProvide neeRlUSA department of Health Services Policyand PracticeSchool of Public HealthBrown University121 South Main StreetBox G-121S-2ProvidenceRl 02912USA National Institute of Public Health(INSP) CuernavacaMorelosMexico department of Behavioral and Social Science School of Public HealthBrown UniversityProvidenceRlUSA Fenway Health and Harvard University BostonMAUSA.

Background:Male sex workers are at high-risk for acquisition of sexually transmitted infections(STIs),including human immunodeficiency virus(HIV).We quantified incidence rates of STIs and identified their time-varying predictors among male sex workers in Mexico ***:From January 2012 to May 2014,male sex workers recruited from the largest HIV clinic and community sites in Mexico City were tested for chlamydia,gonorrhea,syphilis,hepatitis,and HIV at baseline,6-months,and *** nee rates with 95%bootstrapped confide nee limits were *** examined potential timevarying predictors using generalized estimating equations for a population averaged ***:Among 227 male sex workers,median age was 24 and baseline HIV prevalence was 32%.Incidence rates(per 100 person-years)were as follows:HIV[5.23;95%confidence interval(CI):2.15-10.31],chlamydia(5.15;95%CI:2.58-9.34),gonorrhea(3.93;95%CI:1.88-7.83),syphilis(13.04;95%CI:8.24-19.94),hepatitis B(2.11;95%CI:0.53-4.89),hepatitis C(0.95;95%CI:0.00-3.16),any STI except HIV(30.99;95%CI:21.73-40.26),and any STI including HIV(50.08;95%CI:37.6062.55).In the multivariable-adjusted model,incident STI(excluding HIV)were lower among those who reported consistently using condoms during anal and vaginal intercourse(odds ratio=0.03,95%CI:0.00-0.68)compared to those who reported inconsistently using condoms during anal and vaginal ***:Incidence of STIs is high among male sex workers in Mexico *** condom use is an important protective factor for STIs,and should be an important comp on ent of interventions to prevent incide nt infect i ons.

关键词： Male sex worker Men who have sex with men HIV Sexually transmitted infection Transmission Risk factor Mexico

腹腔镜分期在子宫、卵巢、输卵管及原发腹膜恶性肿瘤分期不完全时的应用:妇科肿瘤协作组(GOG)的研究

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世界核心医学期刊文摘（妇产科学分册） 2006年第3期2卷 16-17页

作者： Spirtos N.M. Eisekop S.M. Boike G. d. Mackey 高雪莲 Gynecologic Oncology Group 1600 John F. Kennedy Blvd Philadelphia PA 19103 United States

Objective: The purpose of this study was to determine the feasibility of laparoscopically staging patients with incompletely staged cancers of the uterus, ovary, fallopian tube, and primary peritoneum, and to evaluate related effects. Study design: Patients without evidence of metastatic disease had laparoscopic bilateral para-aortic and pelvic lymph node dissection. Other procedures were individualized based on extent of the primary surgery; laparotomy was undertaken for identified resectable disease. Results: Ninety-five eligible patients were entered on 2 Gynecologic Oncology Group (GOG) protocols. Eleven were excluded. Fifty-eight patients (69%) underwent complete endoscopic staging with photographic documentation. Nine others (10%) were incompletely staged. Seventeen patients (20%) had laparotomy. In patients undergoing laparoscopy, 6%had bowel complications; 11%were found to have more advanced disease. Hospital stay was significantly shorter with laparoscopy alone (3 vs 6 days, P = .04). Conclusion: Interval laparoscopic staging of gynecologic malignancies can be successfully undertaken in selected patients, but laparotomy for adhesions or metastatic disease and risk of visceral injury may be anticipated.

关键词：妇科肿瘤 GOG 腹膜恶性肿瘤腔镜腹腔镜手术开腹手术妇科恶性肿瘤肠道并发症开腹探查术研

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环境公民诉讼三十年：庆祝与峰会

中国地质大学学报（社会科学版） 2018年第4期18卷 36-68页

作者：詹姆斯·R.梅王曦(译) 杨亚辉(译) 布鲁斯·J.特里斯齐格蒙特·J.B.普莱特安·鲍尔斯迈克尔·d.亚瑟兰大卫·布克班德彼得·雷纳小罗伯特·F.肯尼迪卢锟(校) 怀德纳大学法学院波士顿学院法学院佩斯大学俄勒冈州大学法学院法塞拉俱乐部哈德逊河保护基金佩斯大学自然资源保护协会上海交通大学凯原法学院上海200030 上海海洋大学海洋文化与法律学院上海201306

本文根据2003年4月4日在美国特拉华州威尔明顿市举行的"环境公民诉讼30年:庆祝与峰会"专题研讨会的发言记录整理而成。这份材料的价值在于这些发言人都是美国公民诉讼制度的早期倡导者和著名实践者。他们的发言回顾了这个制度诞生的历... 详细信息

本文根据2003年4月4日在美国特拉华州威尔明顿市举行的"环境公民诉讼30年:庆祝与峰会"专题研讨会的发言记录整理而成。这份材料的价值在于这些发言人都是美国公民诉讼制度的早期倡导者和著名实践者。他们的发言回顾了这个制度诞生的历史背景和早期的司法实践。对于研究美国公民诉讼制度而言,这些发言无疑具有独特的史料价值。

关键词：美国环境法公民诉讼环境法律师公民讼诉立法史

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急性卒中影像学研究路径图Ⅱ

国际脑血管病杂志 2014年第2期22卷 81-92页

作者： Max Wintermark Gregory W. Albers Joseph P. Broderick Andrew M. demchuk Jochen B. Fiebach Jens Fiehler James C. Grotta Gary Houser Tudor G. Jovin kennedy R. Lees Michael H. Lev david S. Liebeskind Marie Luby Keith W. Muir Mark W. Parsons Rudiger von Kummer Joanna M. Wardlaw Ona Wu Albert J. Yoo Andrei V. Alexandrov Jeffry R. Alger Richard I. Aviv Roland Bammer Jean-Claude Baron Fernando Calamante Bruce C.V. Campbell Trevor C. Carpenter Sφren Christensen William A. Copen Colin P. derdeyn E. Clarke Haley Jr Pooja Khatri Kohsuke Kudo Maarten G. Lansberg Lawrence L. Latour Ting-Yim Lee Richard Leigh Weili Lin Patrick Lyden Grant Mair Bijoy IC Menon Patrik Michel Robert Mikulik Raul G. Nogueira Left φstergaard Salvador Pedraza Christian H. Riedel Howard A. Rowley Pina C. Sanelli Makoto Sasaki Jeffrey L. Saver Pamela W. Schaefer Peter d. Schellinger Georgios Tsivgoulis Lawrence R. Wechsler Philip M. White Greg Zaharchuk Osama O. Zaidat Stephen M. davis Geoffrey A. donnan Anthony J. Furlan Werner Hacke dong-Wha Kang Chelsea Kidw ell Vincent N. Thijs Gotz Thomalla Steven J. Warach 严晓铭刘牧张晶晶柯开富不详南通大学附属医院神经内科 226001

卒中影像学研究组（StrokeImagingResearchGroup，STIR）、美国神经放射学学会和美国神经放射学学会基金会在过去1年多的时间时举办了一系列的工作会议，最后一次会议于2013年3月9日至10日在华盛顿召开的卒中治疗专业学术圆桌会议（Stro... 详细信息

卒中影像学研究组（StrokeImagingResearchGroup，STIR）、美国神经放射学学会和美国神经放射学学会基金会在过去1年多的时间时举办了一系列的工作会议，最后一次会议于2013年3月9日至10日在华盛顿召开的卒中治疗专业学术圆桌会议（Stroke Treatment Academy Industry Roundtable，STAIR）期间举行。

关键词：急性卒中影像学神经放射学路径会议基金会学会美国

喉痉挛:X染色体脊髓延髓肌萎缩症的未确诊症状

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世界核心医学期刊文摘（神经病学分册） 2005年第8期1卷 56-56页

作者： Sperfeld A.-d. Hanemann C.O. Ludolph A.C. Kassubek J. 姚庆和 department of Neurology University of Ulm Oberer Eselsberg 45 89081 Ulm Germany Dr.

The authors reviewed the occurrence and concomitant factors of laryngospasm in X-linked spinobulbar muscular atrophy(kennedy disease [Kd]).Recurrent laryngos pasm was observed in 47%of 49 patients with Kd, but in only... 详细信息

关键词： X染色体肌萎缩喉痉挛

The enhanced X-ray Timing and Polarimetry mission—eXTP

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Science China(Physics,Mechanics & Astronomy) 2019年第2期62卷 3-27页

作者： ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra de Rosa YongWei dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas dauser Ettore del Monte Sergio di Cosimo Sebastian diebold Victor doroshenko Michal dovciak YuanYuan du Lorenzo ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu Yudong Gu daWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang dianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu Wenda Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Key Laboratory for Particle Astrophysics Institute of High Energy PhysicsChinese Academy of Sciences Institut für Astronomie und Astrophysik Eberhard Karls Universität INAF-Istituto di Astrofisica e Planetologia Spaziali INFN-Roma Tor Vergata Via della Ricerca Scientifica 1 department of Engineering Physics and Center for Astrophysics Tsinghua University dTU Building 327DK-2800 Kongens Institute of Space Sciences 08193 Cerdanyola del Valles Institut d’Estudis Espacials de Catalunya Sezione di Pisa Istituto Nazionale di Fisica NucleareLargo Bruno Pontecorvo3 department of Astronomy University of Genevachemin d’Ecogia 16 Osservatorio di Astrofisica e Scienza dello Spazio di Bologna Istituto Nazionale di Astofisica Astronomical Institute Czech Academy of Sciences Max Planck Institute for Extraterrestrial Physics Giessenbachstr.1 CEA Paris-Saclay/IRFU Beijing Institute of Spacecraft System Engineering CAST Osservatorio Astronomico di Brera Istituto Nazionale di Astofisica Space Research Center Polish Academy of Sciences Key Laboratory of Advanced Material Microstructure of Education Ministry of China Institute of Precision Optical EngineeringSchool of Physics Science and EngineeringTongji University department of Physics and Center for Astrophysics Tsinghua University Universita’degli Studi di Udine Via delle Scienze 206 Mullard Space Science Laboratory University College London department of Nuclear and Particle Physics University of Geneva SRON Netherlands Institute for Space Research Politecnico di Milano Sezione di Perugia Istituto Nazionale di Fisica Nucleare dipartimento di Fisica e Chimica Fondazione Bruno Kessler dr.Karl Remeis-Observatory and Erlangen Centre for Astroparticle Physics Universität Erlangen-Nürnberg University of Pavia Department of ElectronicsInformation and Biomedical Engineering and INFN Pavia Sezione di Torino Istituto Nazionale di Fisica NucleareVia Pietro Giuria1 department of Physics and Astronomy University of Leicester Sezione di Trieste Istituto Nazionale di Fisica Nucleare

In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QEd, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave *** paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment.

关键词： X-ray instrumentation X-ray polarimetry X-ray timing space mission:eXTP