检索结果-南通市图书馆

维普期刊数据库

抗坏血酸肾上腺素悬液对于支气管性气喘之治疗

在线全文

学校读者我要写书评

暂无评论

中华医学杂志 1942年第9期28卷 319-320页

作者： kennedy a.

对於支气管性气喘之急切治疗,舍肾上腺素外,尚无他药可以完全代替之。然肾上腺素之吸收及破坏作用极为迅速,而收效至暂,且亦不易控制。自麻黄素问世後,颇多气喘患者因得夜间安眠,白昼工作如常。但除轻性病例外,此药对於支气管扩张作用,...

对於支气管性气喘之急切治疗,舍肾上腺素外,尚无他药可以完全代替之。然肾上腺素之吸收及破坏作用极为迅速,而收效至暂,且亦不易控制。自麻黄素问世後,颇多气喘患者因得夜间安眠,白昼工作如常。但除轻性病例外,此药对於支气管扩张作用,力量犹嫌不足耳。

关键词：

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

一九八四年度露天开采年评

中国矿山工程 1985年第2期 22-33页

作者： Bruce a. kennedy 王煦华周致勤

虽然,1983年普遍开始经济恢复,但对采矿方面的影响不太快。该年金属价格最好也不过是中等水平,肯定低于七十年代后期的水平。随着矿石品位普遍下降,露天矿工作者再次进行试验,以便维持经济的服务期限。

关键词：分公司露天矿厂家车队矿山汽车皮带运输机挖掘机械挖掘机柴油发动机履带式推土机矿山公路铲运机吨/小时露天采矿矿山开采露天开采年评

合生素治疗(长双歧杆菌/Synergy1)可促进活动性溃疡性结肠炎患者炎症消退:一项随机对照初步试验

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（胃肠病学分册） 2005年第7期1卷 29-30页

作者： Furrie E. Ma.fa.la.e S. kennedy a. 陈云茹 Microbiology a.d Gut Biology Group University of Dundee Ninewells Hospital Medical School Dundee DD1 9SY United Kingdom Dr.

Ba.kground a.d a.ms: Ulcera.ive colitis (UC) is a. a.ute a.d chronic infla.ma.tory disea.e of the la.ge bowel with unknown a.tiology. The immune response a.a. nst norma. commensa. microorga.isms is believed to drive infla.ma.ory processes a.socia.ed with UC. Therefore, modula.ion of ba.teria. communities on the gut mu cosa. through the use of probiotics a.d prebiotics, ma. be used to modify the di sea.e sta.e. Methods: a.synbiotic wa. developed for use in UC pa.ients combining a.probiotic, Bifidoba.terium longum, isola.ed from hea.thy recta. epithelium, a.nd a.prebiotic (Synergy 1), a.preferentia. inulinoligofructose growth substra.e for the probiotic stra.n. Trea.ment wa. employed in a.double blinded ra.domised controlled tria. using 18 pa.ients with a.tive UC for a.period of one month. Clinica. sta.us w a. scored a.d recta. biopsies were collected before a.d a.ter trea.ment, a.d tra.nscription levels of epithelium rela.ed immune ma.kers were mea.ured. Results: S igmoidoscopy scores (sca.e 0- 6)were reduced in the test group (sta.t 4.5 (1.4) , end 3.1 (2.5)) compa.ed with pla.ebo (sta.t 2.6 (2.1), end 3.2 (2.2)) (p=0.06) . mRNa.levels for huma. beta.defensins 2, 3, a.d 4, which a.e strongly upregula. ed in a.tive UC, were significa.tly reduced in the test group a.ter trea.ment (p = 0.016, 0.038, a.d 0.008, respectively). Tumour necrosis fa.tor α a.d interl eukin 1α , which a.e infla.ma.ory cytokines tha. drive infla.ma.ion a.d induce defensin expression, were a.so significa.tly reduced a.ter trea.ment (p = 0.018 a.d 0.023, respectively). Biopsies in the test group ha. reduced infla.ma.ion a. d regenera.ion of epithelia. tissue. Conclusions: Short term synbiotic trea.ment of a.tive UC resulted in improvement of the full clinica. a.pea.a.ce of chronic infla.ma.ion in pa.ients receiving this thera.y.

关键词：溃疡性结肠炎 Synergy1 长双歧杆菌合生素免疫标记物肠黏膜疾病病程低聚果糖 β防御素活检标本

维普期刊数据库

在线全文

学校读者我要写书评

暂无评论

企业文化

企业文化

Expla.na.le a.-Ba.ed DDoS a.ta.ks Cla.sifica.ion Using Deep Tra.sfer Lea.ning

作者： (美)特伦斯·迪尔(Terrence E. Dea.)，(美)艾伦·肯尼迪(a.la. a. kennedy)

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

Computers, Ma.eria.s a.d Continua 2024年第3期80卷 3785-3802页

作者： a.zu’bi a. a.ba.ha.reh a. a.ua.qoub a. a.fa.a.r M.a.M. Depa.tment of Computer Science Jordan University of Science and Technology Irbid 22110 Jordan Depa.tment of Computer Science The University of Jordan Amman 11942 Jordan Ca.diff School of Technologies Cardiff Metropolitan University Cardiff CF5 2YB United Kingdom Prince a.dulla. bin Gha.i Fa.ulty of Informa.ion a.d Communica.ion Technology Al-Balqa Applied University Salt 19117 Jordan

In the era.of the Internet of Things (IoT), the prolifera.ion of connected devices ha. ra.sed security concerns, increa.ing the risk of intrusions into diverse systems. Despite the convenience a.d efficiency offered by IoT technology, the growing number of IoT devices esca.a.es the likelihood of a.ta.ks, empha.izing the need for robust security tools to a.toma.ica.ly detect a.d expla.n threa.s. This pa.er introduces a.deep lea.ning methodology for detecting a.d cla.sifying distributed denia. of service (DDoS) a.ta.ks, a.dressing a.significa.t security concern within IoT environments. a. effective procedure of deep tra.sfer lea.ning is a.plied to utilize deep lea.ning ba.kbones, which is then eva.ua.ed on two benchma.king da.a.ets of DDoS a.ta.ks in terms of a.cura.y a.d time complexity. By levera.ing severa. deep a.chitectures, the study conducts thorough bina.y a.d multicla.s experiments, ea.h va.ying in the complexity of cla.sifying a.ta.k types a.d demonstra.ing rea.-world scena.ios. a.ditiona.ly, this study employs a. expla.na.le a.tificia. intelligence (Xa.) a. technique to elucida.e the contribution of extra.ted fea.ures in the process of a.ta.k detection. The experimenta. results demonstra.e the effectiveness of the proposed method, a.hieving a.reca.l of 99.39% by the Xa. bidirectiona. long short-term memory (Xa.-BiLSTM) model. Copyright © 2024 The a.thors. Published by Tech Science Press.

关键词： cybersecurity DDoS a.ta.k cla.sifica.ion deep lea.ning expla.na.le a.

Outcomes following minima.ly inva.ive dorsa. cheilectomy for ha.lux rigidus:a.systema.ic review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journa. of Orthopedics 2024年第6期15卷 585-592页

作者： Ka.herine Esser Ja.es J Butler Ma.kenzie Roof Na.ha.iel P Mercer Micha.l C Ha.rington a.a. P Sa.sonov a.drew J Rosenba.m John G kennedy Depa.tment of Orthopa.dic Surgery University of Toledo Medica. Center University of Toledo College of Medicine and Life SciencesToledoOH 43614United States Depa.tment of Orthopedic Surgery NYU Langone HealthNew YorkNY 10002United States Depa.tment of Orthopedic Surgery Albany Medical CenterAlbanyNY 12208United States

Ba.KGROUND Cheilectomy of the 1^(st)meta.a.sopha.a.gea. joint(MTPJ)is one of the most common procedures for the ma.a.ement of ha.lux ***,there is no consensus rega.ding outcomes following minima.ly inva.ive dorsa. cheilectomy(MIDC)for the ma.a.ement of ha.lux *** To eva.ua.e outcomes following MIDC for the ma.a.ement of ha.lux *** During November 2023,the PubMed,EMBa.E a.d Cochra.e Libra.y da.a.a.es were systema.ica.ly reviewed to identify clinica. studies exa.ining outcomes following MIDC for the ma.a.ement of ha.lux *** Six studies were *** tota.,348 pa.ients(370 feet)underwent MIDC for ha.lux rigidus a. a.weighted mea. follow-up of 37.9±16.5 *** distribution of pa.ients by Coughlin a.d Shurna.s cla.sifica.ion wa. recorded in 4 studies a. follows:Ⅰ(58 pa.ients,27.1%),Ⅱ(112 pa.ients,52.3%),Ⅲ(44 pa.ients,20.6%).Three studies performed a. a.ditiona. 1^(st)MTPJ a.throscopy a.d debridement following *** intra.a.ticula. bone debris wa. observed in 100%of pa.ients in 1 *** weighted mea. a.erica. orthopedic foot a.d a.kle society score improved from a.preopera.ive score of 68.9±3.2 to a.postopera.ive score of *** complica.ion ra.e wa. 8.4%,the most common of which wa. persistent joint pa.n a.d ***-two fa.lures(8.7%)were ***-three seconda.y procedures(8.9%)were performed a. a.weighted mea. time of 8.6±3.2 months following the index *** This systema.ic review demonstra.ed improvements in subjective clinica. outcomes together with a.modera.e complica.ion ra.e following MIDC for the ma.a.ement of ha.lux rigidus a. short-term follow-up.a.modera.e reopera.ion ra.e a. short-term follow-up wa. *** ma.ked heterogeneity between included studies a.d pa.city of high qua.ity compa.a.ive studies limits the genera.ion of a.y robust conclusions.

关键词： Minima.ly inva.ive dorsa. cheilectomy Ha.lux rigidus The first meta.a.sopha.a.gea. joint Cheilectomy Minima.ly inva.ive surgery

Ta.geting a.PKa. Gene in PC3 Cells by Triphenylmetha.ol Deriva.ives

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Na.ura. Science 2024年第7期16卷 111-120页

作者： Willia. Ya. Boa.i Ja.a.i Jemison kennedy Welbert Sa.a. Dudley Ta.a.la.Hizer Rya. Beni Depa.tments of Chemistry a.d Biology Tennessee State University Nashville USA

Epidemiologica. studies indica.e tha. trea.ment with metformin, a. a.P-a.tiva.ed protein kina.e (a.PK) a.tiva.or, reduces the incidence of ca.cers. a.tiva.ion of a.PK ha. a.so been reported to oppose tumor progression in diverse types of ca.cers a.d offers promising ca.cer thera.y. Furthermore, a.PK is a.prima.y regula.or of energy meta.olism a.d ha. a.so been implica.ed in cell cycle progression, a.giogenesis, cell tra.sforma.ion, migra.ion, a.d ca.cer. We ha.e recently synthesized novel fla.onoids, na.ely, triphenylmetha.ol deriva.ives (TPMs), but the effectiveness of the TPMs on the a.tivity of a.PK rema.ns unclea.. We hypothesized tha. the novel TPMs would inhibit ca.cer cell prolifera.ion through the a.tiva.ion of a.PK isoforms in cells. The effects of TPMs on prosta.e cells (PC-3) were investiga.ed. Cells were exposed to TPMs for either 12 or 24 hr. a. the respective doses of 0, 25, 50 100, a.d 200 µM ba.ed on the cell via.ility studies by the (3-(4,5-dimethylthia.ol-2-yl)-2,5-diphenyltetra.olium bromide, a.tetra.ole) (MTT) a.sa.. The results indica.e tha. cells exposed to the respective doses of TPMs increa.ed both phospho- a.d tota.-a.PKα1 in a.dose- a.d time-dependent ma.ner. The effects of the increa.es for the phospho- a.d tota.-a.PKα in cells were grea.er for the 24-hr tha. the 12-hr. incuba.ion. Further studies a.e currently going on to elucida.e the specificities of the sa.d insults in increa.ing the phospho- a.d tota.-a.PKα a.tivities a.d for the other respective isoforms.

关键词： Prodrugs a.P-a.tiva.ed Protein Kina.e Polyphenols Prosta.e Ca.cer Triphenylmetha.ol

Kinema.ics of ma.dibula. a.va.cement devices (Ma.s): Why do some Ma.s move the lower ja. ba.kwa.d during mouth opening?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

BIO-DESIGN a.D Ma.UFa.TURING 2024年第5期7卷 637-650页

作者： Ca.rera. Jua. a. Ba.a.ler, a.ex Postigo, Sergio Ga.cia. Ma.cos Univ Ma.a.a Mech Engn Dept Malaga 29071 Spain

Ma.dibula. a.va.cement devices (Ma.s) a.e widely used trea.ments for obstructive sleep a.nea. Ma.s function by a.va.cing the lower ja. to open the upper a.rwa.. To increa.e pa.ient comfort, most pa.ients a.low the mouth to be opened. However, not a.l systems ma.nta.n the lower ja. in a.forwa.d position during mouth opening, which results in the production of a.retrusion tha. fa.ors the colla.se of the upper a.rwa.. Furthermore, the kinema.ic beha.ior of the mecha.ism formed by the ma.dible-device a.sembly depends on ja. morphology. This mea.s tha., during mouth opening, some devices ca.se lower ja. protrusion in some pa.ients, but ca.se its retra.tion in others. In this study, we report the beha.ior of well-known devices currently on the ma.ket. To do so, we developed a.kinema.ic model of the lower ja. device a.sembly. This model wa. va.ida.ed for a.l devices a.a.yzed using a.high-resolution ca.era.system. Our results show tha. some of the devices a.a.yzed here did not produce the correct beha.ior during pa.ient mouth opening. (sic)(sic)(sic)(sic)(sic)(sic)(sic)a.enthesis>Ma.sa.enthesis>(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)a.hic Full Stop>Ma.s(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)a.hic Full Stop>(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic), (sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)a.hic Full Stop>(sic)(sic), (sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic), (sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)a.hic Full Stop>(sic)(sic), (sic)(sic)-(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)a.hic Full Stop>(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic), (sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(

关键词： Ma.dibula. a.va.cement devices Lower ja. kinema.ics Sleep a.nea OBSTRUCTIVE SLEEP-a.NEA ORa. a.PLIa.CES MECHa.ISM DESIGN MOTION

Clima.e Trends a.d Their Impa.t on Sorghum Production in Ma.iga., Ba.ingo County: a.Historica. a.a.ysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journa. of Modern Hydrology 2024年第2期14卷 106-129页

作者： kennedy O. Okuku Ja.heth O. Onya.do Romulus O. Okwa.y Clement K. Kiptum Depa.tment of a.ricultura. Engineering Egerton University Nakuru Kenya School of Engineering University of Eldoret Eldoret Kenya

Clima.e is subject to fluctua.ions in the ma.ority of the world, ma.nly ca.sed by ra.nfa.l a. well a. tempera.ure va.ia.ions. Clima.e fluctua.ions in Kenya.ha.e resulted in the sprea. of desert-like conditions in the a.a.s region, such a. Ma.iga. in Ba.ingo County. a. a.county, Ba.ingo experiences grea. va.ia.ions in clima.e a.nua.ly, a. well a. uncerta.nty in expected ra.ns, thereby nega.ively impa.ting the production of crops such a. sorghum. This study a.plied the ra.nfa.l a.oma.y index (Ra.), sta.da.dised precipita.ion eva.otra.spira.ion index (SPEI), sta.da.d precipita.ion index (SPI), a.d Ma.n-Kenda.l (MK) sta.istica. test for trends on historica. clima.ic da.a.in a.a.ysing both tempera.ure a.d precipita.ion da.a.over the period 1990 to 2022 to determine their trend, pa.terns a.d how they a.fect the production of sorghum crops. The ma.hine lea.ning method (R studio) with inputs wa. used to ca.cula.e the SPI, SPEI, Ra. a.d MK trend test. The ra.nfa.l va.ied from below a.era.e to a.ove a.era.e during the study period with no clea. pa.tern in the Ra., SPEI a.d SPI va.ues. The yea.s 2020 a.d 2000 stood out a. they ha. higher a.d lower ra.nfa.l tha. usua., respectively. The Ma.iga. a.ea.genera.ly experienced more ra.nfa.l during the high/long ra.nfa.l sea.on (a.JJ). The MK trend test on a.era.e monthly ra.nfa.l, SOND, a.JJ, a.d a.nua. precipita.ion confirmed a.positive trend in precipita.ion. However, the short ra.ny sea.on (SOND) wa. found to be the most va.ia.le period for ra.nfa.l, a.d there wa. a.slight increa.e in da.ly a.era.e tempera.ures during this sea.on.

关键词： Trends Precipita.ion Tempera.ure Ra. SPI SPEI a.d MK