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Long-term disease-free survival in a dog with appendicular osteosarcoma

畜牧与兽医 2012年第S2期44卷 62-62页

作者： Kumiko Ishigaki Kazushi Asno Yoshiya Yoshida Rikiya Nishimura Hiromi Aoki Gentoku iida Orie Yoshida Mamiko Seki kenji Teshima Kazuya Edamura Animal Medical Center Nihon University Laboratory of Veterinary Surgery Department of Veterinary Medicine College of Bioresource SciencesNihon University SHIMA Laboratories Co. LTD Laboratory of Comprehensive Veterinary Clinical Studies Department of Veterinary Medicine College of Bioresource SciencesNihon University

Postoperative prognosis is generally poor even with adjuvant chemotherapy in dogs with an appendicular osteosarcoma. The purpose of this report was to present the long-term disease-free survival time in a dog with appendicular osteosarcoma receiving amputation,adjuvant chemotherapy and adoptive immunotherapy. A 12-year-old spayed Golden retriever was referred to our hospital with a suspicion of osteosarcoma in right distal radius. The patient underwent the computed tomography (CT) and incisional biopsy on the next day after the first presentation. The CT revealed the osteolysis in the right distal radius and no metastases in the lungs and lymph nodes. The histopathologic diagnosis was made as an osteosarcoma. On the 13th day after,the patient underwent right forelimb amputation. Six doses of carboplatin (250 mg / m2) were postoperatively administered every 3 weeks. The intravenous infusion of lymphokine-activated killer (LAK) cells suspension was performed every 3 ~ 4 weeks after the adjuvant chemotherapy. At the time of our writing this abstract (on the 880thday after the first presentation),no recurrences and metastases were observed after the 32 transfers of LAK cells. In canine appendicular osteosarcoma,some reports have described that postoperative median survival times were 235 ~ 540 d with adjuvant chemotherapy. In our report,the disease free interval and survival time were prolonged compared with the previous reports. We strongly believed that early diagnosis and surgical intervention and adoptive immunotherapy had a great impact on the improvement of survival time in canine appendicular osteosarcoma.

关键词： adoptive immunotherapy adjuvant chemotherapy appendicular osteosarcoma,dog long-term disease-free survival

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Use of cone-shaped polypropylene mesh for perineal herniorrhaphy in dogs

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畜牧与兽医 2012年第S2期44卷 43-43页

作者： kenji Teshima Kazushi Asano Kumiko Ishigaki Mamiko Seki Takahiro Suzuki Seri Komazaki Gentoku iida Orie Yoshida Kazuya Edamura Shigeo Tanaka Animal Medical Center Nihon University Laboratory of Veterinary Surgery Department of Veterinary MedicineCollege of Bioresource SciencesNihon University Laboratory of Comprehensive Veterinary Clinical Studies Department of Veterinary MedicineCollege of Bioresource SciencesNihon University

Unilateral or bilateral perineal hernia results from the failure of the muscular pelvic diaphragm,and is commonly observed in male *** study aimed to investigate the outcome of herniorrhaphy technique with the cone-shaped polypropylene mesh in dogs with perineal hernia.1 Materials and Methods Between October 2008 and July 2012,39 dogs(71 perineal hernias)underwent herniorrhaphy with polypropylene mesh(PROLENE MeshJohnson&Johnson)formed in the shape of a *** apex of corn-shaped mesh was inserted into the hernia region,and the bottom was sutured to sacrotuberous ligament,internal obturator muscle,external anal sphincter and residual coccygeal muscle.

关键词： polypropylene shaped hernia muscular bilateral obturator sphincter inserted ligament diaphragm

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维普期刊数据库

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