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Employing electricity-consumption monitoring systems and integrative time-series analysis models： A case study in Bogor, Indonesia

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Frontiers in Energy 2018年第3期12卷 426-439页

作者： Seiya MAKI Shuichi ASHINA Minoru FUJII Tsuyoshi FUJITA Norio YABE kenji uchida Gito GINTING Rizaldi BOER Remi CHANDRAN National Institute for Environmental Studies Tsukuba city Ibaraki 305-8506 Japan Fujitsu Company Chiba city 261-8588 Chiba Japan Bogor Agricultural University (IPB) JI Pajajaran No. 1 Bogor West Java16143 Indonesia

The Paris Agreement calls for maintaining a global temperature less than 2℃ above the pre-industrial level and pursuing efforts to limit the temperature increase even further to 1.5℃. To realize this objective and promote a low-carbon society, and because energy production and use is the largest source of global greenhouse-gas （GHG） emissions, it is important to efficiently manage energy demand and supply systems. This, in turn, requires theoretical and practical research and innovation in smart energy monitoring technologies, the identification of appropriate methods for detailed time-series analysis, and the application of these technologies at urban and national scales. Further, because developing countries contribute increasing shares of domestic energy consumption, it is important to consider the application of such innovations in these areas. Motivated by the mandates set out in global agreements on climate change and low-carbon societies, this paper focuses on the development of a smart energy monitoring system （SEMS） and its deployment in house- holds and public and commercial sectors in Bogor, Indonesia. An electricity demand prediction model is developed for each device using the Auto-Regression eXogenous model. The real-time SEMS data and time- series clustering to explore similarities in electricity consumption patterns between monitored units, such as residential, public, and commercial buildings, in Bogor is, then, used. These clusters are evaluated using peak demand and Ramadan term characteristics. The resulting energy- prediction models can be used for low-carbon planning.

关键词： electricity monitoring electricity demandprediction multiple-variable time-series modeling time-series cluster analysis Indonesia

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Impact of diabetes on long term follow-up of elderly patients with chronic total occlusion post percutaneous coronary intervention

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Journal of Geriatric Cardiology 2013年第1期10卷 16-20页

作者： Wei Liu kenji Wagatsuma Hideo Nii Mikihito Toda Hideo Amano Yasuto uchida Division of Interventional Cardiology Cardiovascular Center Toho University 6-11-1 Omori-Nishi Ota-K Tokyo 143-8541 Japan Department of Cardiology Beijing An Zhen Hospital Capital Medical University Chao Yang District Beijing 100029 China Division of Interventional Cardiology Cardiovascular Center Toho University 6-11-1 Omori-Nishi Ota-K Tokyo 143-8541 Japan

Ba ckground The prognosis of elderly patients with chronic total occlusion (CTO) and diabetes mellitus (DM) treated with percutaneous coronary intervention (PCI) is not known. Objective To investigate the effect of diabetes on long-term follow-up of CTO after PCI in elderly *** A total of 153 elderly patients (age > 65 years old) with CTO lesions which were successfully treated with PCI were enrolled. Fifty one patients with diabetes and 102 without diabetes were compared for long-term outcomes (mean follow up: 36 ±12 months). Major adverse cardiac events (MACE) which include death, myocardial infarction or target lesion revascularization (TLR) were considered as a combined endpoint. Results The combined endpoint occurred in 29.4% of diabetes patients, and 11.3% of the patients without diabetes (P < 0.05). The Cox proportional hazards model identified: drug eluting stent (DES) or bare metal stent (BMS) (HR: 0.13, 95% confidence interval (95%CI): 0.03–0.62, P = 0.004), DM(HR: 6.69, 95% CI: 1.62–15.81, P = 0.01) and final minimal lumen diameter (MLD) (HR: 0.37, 95% CI: 0.13–0.90, P = 0.03 ) as independent predictors of MACE, DM with renal impairment (HR: 6.64, 95% CI: 1.32–33.36, P = 0.02), HBA1C on admission (HR: 1.79, 95% CI: 1.09–2.94, P = 0.02), as independent predictors of MACE at long term follow-up. Conclusions The study demonstrates that DMis a predictive factor for MACE in elderly CTOpatients treatedwith PCI, type of stent, final minimal lumen diameter and DMwith renal impairment, and HBA1C level on admission are predictors of MACE.

关键词： Chronic total occlusion Diabetes Drug eluting stent Elderly patient Percutaneous coronary intervention

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Effects of an oral iron chelator, deferasirox, on advanced hepatocellular carcinoma

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World Journal of Gastroenterology 2016年第40期22卷 8967-8977页

作者： Issei Saeki Naoki Yamamoto Takahiro Yamasaki Taro Takami Masaki Maeda Koichi Fujisawa Takuya Iwamoto Toshihiko Matsumoto Isao Hidaka Tsuyoshi Ishikawa Koichi uchida kenji Tani Isao Sakaida Department of Gastroenterology and Hepatology Yamaguchi University Graduate School of Medicine Yamaguchi 755-8505 Japan Yamaguchi University Health Administration Center Yamaguchi 755-8511 Japan Department of Oncology and Laboratory Medicine Yamaguchi University Graduate School of Medicine Yamaguchi 755-8505 Japan Department of Human Nutrition Faculty of Nursing and Human Nutrition Yamaguchi 755-8502 Japan Center of Research and Education for Regenerative Medicine Yamaguchi University Graduate School of Medicine Yamaguchi Prefectural University Yamaguchi 755-8505 Japan Department of Veterinary Surgery Joint Faculty of Veterinary Medicine Yamaguchi University Yamaguchi 755-8511 Japan

AIM To evaluate the inhibitory effects of deferasirox(DFX) against hepatocellular carcinoma(HCC) through basic and clinical *** In the basic study, the effect of DFX was investigated in three hepatoma cell lines(Hep G2, Hep3 B, and Huh7), as well as in an N-nitrosodiethylamine-induced murine HCC model. In the clinical study, six advanced HCC patients refractory to chemotherapy were enrolled. The initial dose of DFX was 10 mg/kg per day and was increased by 10 mg/kg per day every week, until the maximum dose of 30 mg/kg per day. The duration of a single course of DFX therapy was 28 consecutive days. In the event of dose-limiting toxicity(according to the Common Terminology Criteria for Adverse Events v.4.0), DFX dose was *** Administration of DFX inhibited the proliferation of hepatoma cell lines and induced the activation of caspase-3 in a dose-dependent manner in vitro. In the murine model, DFX treatment significantly suppressed the development of liver tumors(P < 0.01), and significantly upregulated the mR NA expression levels of hepcidin(P < 0.05), transferrin receptor 1(P < 0.05), and hypoxia inducible factor-1α(P < 0.05) in both tumor and non-tumor tissues, compared with control mice. In the clinical study, anorexia and elevated serum creatinine were observed in four and all six patients, respectively. However, reduction in DFX dose led to decrease in serum creatinine levels in all patients. After the first course of DFX, one patient discontinued the therapy. We assessed the tumor response in the remaining five patients; one patient exhibited stable disease, while four patients exhibited progressive disease. The one-year survival rate of the six patients was 17%.CONCLUSION We demonstrated that DFX inhibited HCC in the basic study, but not in the clinical study due to dose-limiting toxicities.

关键词：肝肿瘤 Hepatocellular 癌先进舞台 Iron-chelator Deferasirox

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STUDY ON MIXING PERFORMANCE TEST FOR NEW-TYPE MIXER

STUDY ON MIXING PERFORMANCE TEST FOR NEW-TYPE MIXER

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第三届北京国际水泥与混凝土学术会议

作者： kenji Maeda Kazuie Yamada Akira uchida Maeda Corporation TokyoJapan Koichi KishitaniProfessor of Ninon Univ.

INTRODUCTION Various types of concrete mixers have been used for mixing concrete, but they all use the same method. They stir up concrete to obtain even consistency. Our new mixer, instead of mixing , employs a kneading process to improve consistency. This process is very similar to what has traditionally been used in making Japanese noodles. In a typical noodle making, materials are first mixed into dough and then kneaded.

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How to reducePT-GVHD (post- transfusion graft versus host disease) cases

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中国输血杂志 2001年第S1期14卷 285-286页

作者： Takeo Juji Motoko Nishimura Shigeharu uchida Shigeki Mitsunaga Kazunori Nakajima kenji Tadokoro The Japanese Red Cross Central Blood Center The Japanese Red Cross Central Blood CenterThe Japanese Red Cross Central Blood CenterThe Japanese Red Cross Central Blood CenterThe Japanese Red Cross Central Blood CenterTokyo Western Blood CenterJapanese

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Morbidity of Open Saphenous Vein Harvesting after Preoperative Ultrasonic Mapping

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Open Journal of Thoracic Surgery 2015年第1期5卷 4-9页

作者： Susumu Isoda Tamizo Kimura Katsunori Tanaka kenji Nishimura Nozomu Yamanaka Shin-ichi Taguchi Keiji uchida Norihisa Karube Kiyotaka Imoto Department of Cardiovascular Surgery Yokohama City University Medical Center Yokohama Japan Department of Cardiovascular Surgery National Defense Medical College Tokorozawa Japan

Preoperative echography of a saphenous vein graft (SVG) was studied. In 58 cases of consecutive coronary artery bypass grafting, 31 patients underwent SVG echography. Preoperative assessment revealed vein caliber, branching, or varicose saphenous veins. The location of the saphenous vein was marked. Saphenous veins were harvested by the open harvest technique, and the caliber of the veins and the availability of the anastomosis device were recorded. Postoperative morbidity was recorded. Preoperative findings revealed that four (6.5%) of 62 femoral saphenous veins were estimated as “not graftable” because of being a varicose vein or having a small caliber. Seven of 32 lower saphenous veins were estimated as “not graftable”. The mean discrepancy of the caliber was 0.6 mm undersized with preoperative estimation. During harvesting, one of 31 patients had a wrong marking. We were able to use all harvested veins. The morbidity of saphenous harvesting was observed in two (6.5%) of 31 patients. One patient whose marking was wrong had minor skin necrosis. Another patient experienced a hematoma because of the excess effect of warfarin. Preoperative ultrasonic mapping of the saphenous vein reduced useless harvesting, provided information concerning anastomosis device availability, and seemed to reduce morbidity because dissection can be minimal.

关键词： Saphenous Vein Ultrasonic Mapping Coronary Artery Bypass Grafting

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Hepatic clearance measured with ^(99m)Tc-GSA single-photon emission computed tomography to estimate liver fibrosis

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World Journal of Gastroenterology 2014年第44期20卷 16714-16720页

作者： Masahiko Taniguchi Atsutaka Okizaki kenji Watanabe Koji Imai Koichiro uchida Takahiro Einama Noriyuki Shuke Naoyuki Miyokawa Hiroyuki Furukawa Division of Gastroenterologic and General Surgery Department of Surgery Asahikawa Medical College Department of Radiology Asahikawa Medical College Department of Pathology Asahikawa Medical College

AIM: To evaluate the clinical utility of hepatic clearance(HC) measured with technetium-99m-diethylenetriaminepenta-acetic acid-galactosyl human serum albumin(99mTc-GSA) single-photon emission computed tomography(SPECT) to estimate the degree of liver ***:Seventy-eight consecutive patients who underwent initial hepatectomy due to hepatocellular carcinoma were enrolled in this *** green clearance(ICG R15),quantitative indices estimated by 99mTc-GSA[the receptor index(LHL15 and HH15)and HC via SPECT analysis],and conventional liver function tests were performed before *** among the quantitative indices for liver functional reserve,conventional liver function tests,andthe degree of liver fibrosis were ***:The degree of liver fibrosis was correlated with ICG R15,HH15,LHL15,and *** showed the best correlation with conventional liver function *** to multivariate analysis,HC and LHL15 were significant independent predictors of severe *** was the most valuable index for predicting severe ***:HC measured with 99mTc-GSA SPECT is a reliable index for assessing liver fibrosis before hepatectomy.

关键词： Fibrosis Technetium-99m-diethylenetri-aminepenta-a

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Off-Pump Multilayered Sutureless Repair for a Left Ventricular Blowout Rupture after Aortic Dissection Repair

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Open Journal of Thoracic Surgery 2015年第1期5卷 10-14页

A left ventricular (LV) free wall rupture is a highly lethal condition. A 75-year-old female who experienced chest pain was diagnosed as having an acute aortic dissection Stanford type A and underwent emergent surgery. Under cardiopulmonary bypass with LV venting through the right superior pulmonary vein, a proximal aortic stamp was formed. The patient was cooled, selective antegrade brain perfusion was performed, and a hemiarch repair was performed. After the patient was transferred to the intensive care unit, her blood pressure suddenly fell to 50 mmHg. She had a blowout rupture in the left ventricular anterolateral free wall. Since the bleeding hall was not large and the damage to the surrounding left ventricular tissue was not very wide, an off-pump multilayered sutureless repair was performed by using three layers of collagen fleece squares with fibrinogen-based impregnation (TachoComb;CSL Behring, Tokyo, Japan) and three layers of gelatin-resorcin-formalin glue reinforced by an equine pericardial patch (Xenomedica;Edwards Lifesciences, LLC, Irvine, CA). The blow-out rupture seemed to be caused by perioperative myocardial infarction generated by the compression of the left ventricular vent to the LV lateral wall. The patient was free from re-rupture or aneurysm enlargement. The thickness of the hemostatic material seemed to help control the bulging of the aneurysm and to prevent further LV aneurysm enlargement and re-rupture.

关键词： Blowout Cardiac Rupture Sutureless Repair Aortic Dissection TachoComb

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Fibrin Sealant Patch to Treat Dialysis-Associated Hemorrhagic Pericarditis

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Open Journal of Thoracic Surgery 2015年第1期5卷 1-3页

作者： Susumu Isoda Tamizo Kimura Katsunori Tanaka kenji Nishimura Nozomu Yamanaka Shin-ichi Taguchi Norihisa Karube Keiji uchida Kiyotaka Imoto Department of Cardiovascular Surgery Yokohama City University Medical Center Yokohama Japan Department of Cardiovascular Surgery National Defense Medical College Tokorozawa Japan

A 73-year-old male patient with a 3-year history of hemodialysis was admitted for the treatment of pericardial effusion. Echocardiography suggested a diagnosis of effusive pericarditis. Pericardiocentesis was performed several times. Six weeks after the admission, the patient developed cardiac tamponade. Surgical pericardiotomy showed the epicardium had a diffuse shaggy and hemorrhagic surface. To control diffuse oozing, fibrin sealant patches (Tachosil;CSL Behring, Tokyo, Japan) were attached to the epicardium. Oozing was then controlled.

关键词： Fibrin Sealant Patch Hemodialysis Hemorrhage Pericarditis

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超高速氦气系统经皮微球给药研究

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药学学报 2001年第2期36卷 140-144页

作者：金一内田昌希汪成发夏目秀视杉林坚次森本雍宪浙江大学药学院浙江杭州310031 城西大学药学部横店集团康裕药业有限公司浙江东阳322118

目的　研究微球的粒子大小和超高速氦气气流的压力对释放固体微球经皮给药吸收过程的影响。方法利用氦气的超高速流体通过对固体粒子进行加速的方法 ,将药物粉末透过角质层释放到表皮和真皮表面 ,将固体药物粉末通过皮肤释放到体内。结... 详细信息

目的　研究微球的粒子大小和超高速氦气气流的压力对释放固体微球经皮给药吸收过程的影响。方法利用氦气的超高速流体通过对固体粒子进行加速的方法 ,将药物粉末透过角质层释放到表皮和真皮表面 ,将固体药物粉末通过皮肤释放到体内。结果　药物导入率依赖于超高速氦气气流的压力和微球的粒子大小 ,且生物利用度和最高血中浓度也依赖于超高速氦气气流压力的影响。结论　本系统可用于固体药物粉末、多肽类药物。

关键词：微球粒子释放系统超高速氦气系统经皮给药

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