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On the Edge of Web-Based Multiple Sequence Alignment Services

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Tsinghua Science and Technology 2012年第6期17卷 629-637页

作者： ken D. Nguyen Department of Information Technology Clayton State University

There are many web-based multiple sequence alignment services accessible around the world. However, many researchers working on biological sequence analysis still struggle with inefficient, unfriendly user interface, and limited capability multiple sequence alignment software. In this study, we provide a comprehensive survey of regional and continental facilities that provide web-based alignment services. We also analyze and identify much needed services that are not available through these existing service providers. We then implement a web-based model to address these needs. From that perspective, our web-based multiple sequence alignment server, SeqAna, provides a unique set of services that none of these studied facilities have. For example, SeqAna provides a multiple sequence alignment scoring and ranking service. This service, the only of its kind, allows SeqAna＇s users to perform multiple sequence alignment with several alignment tools and rank the results of these alignments in the order of quality. With this service, SeqAna＇s users will be able to identify which alignment tools are more appropriate for their specific set of sequences. In addition, SeqAna＇s users can customize a small alignment sample as a reference for SeqAna to automatically identify the best tool to align their large set of sequences.

关键词： bioinformatics multiple sequence alignment web-services multiple sequence ranking

On ‘Conditionals in English and FOPL’:A Reply to Abbott (2006)

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外国语 2007年第6期30卷 2-20页

作者： ken Turner School of Languages University of Brighton UK

A recent defence of the material analysis of natural indicative conditionals is examined. This defence, it is argued, is initially plausible but ultimately flawed. The empirical and logical case against the material analysis of natural indicative conditionals is made. The empirical and logical arguments are overwhelming and the conclusion is inevitable: natural language indicatives are not material conditionals.

关键词：英语语用学指示条件原始逻辑关联逻辑直观逻辑

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Influence of Heat Treatment on Hydroformability of TRIP Seamless Steel Tube

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Journal of Iron and Steel Research International 2014年第7期21卷 695-701页

作者： Zi-cheng ZHANG ken-ichi MANABE School of Mechanical Engineering and Automation Northeastern University Department of Mechanical Engineering Tokyo Metropolitan University

A low-carbon TRIP seamless steel tube, which is expected to be used in the hydroforming process, was successfully fabricated using piercing, cold-drawing and two-stage heat treatment process. The two-stage heat treatment is one crucial step because it significantly affects the microstructure and mechanical properties of TRIP seam less steel tube. In order to obtain the TRIP seamless steel tube with high hydroformability, several different heat treatment processes were conducted. The effects of heat treatment conditions （intercritical annealing （IA） and isothermal bainite treatment （IBT）） on the TRIP seamless steel tube hydroformability which was determined by free hydraulic bulge test were analyzed. Two different internal pressure boosting velocities of 0.2 and 0.5 MPa/s of free hydraulic bulge tests were adopted to determine the effective stress vs. effective strain curve of TRIP seamless steel tube. The results showed that for the predetermined IA condition, the maximum bulge height increased, but the maximum burst internal pressure decreased, with the increase of IBT holding time from 4 to 6 rain. For the predetermined IBT condition, the maximum bulge height decreased, but the maximum burst internal pressure increased, with the increase of IA holding time from 5 to 10 rain. By analyzing the free hydraulic bulge test results, it was found that the maximum bulge heights of TRIP seamless steel tubes with the internal pressure boosting velocity of 0.5 MPa/s were higher than those when the internal pressure boosting velocity was 0.2 MPa/s. This means that an appropriate deformation rate should be chosen to obtain the optimal hydroformability of TRIP seamless steel tube. In addition, the effective stress vs. effective strain curves of TRIP seamless steel tubes were ohtained with free hydraulic bulge test.

关键词： TRIP steel heat treatment hydroformability seamless tube hydraulic bulge test

Subsidence Analysis and Burial History of the Late Carboniferous to Early Jurassic Soutpansberg Basin,Limpopo Province,South Africa

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Acta Geologica Sinica(English Edition) 2016年第6期90卷 2000-2007页

作者： Ntokozo MALAZA LIU ken ZHAO Baojin Department of Geology University of Fort Hare Worley Parsons 39 Melrose BoulevardMelrose Arch

The subsidence history of the Soutpansberg Basin was reconstructed by a tectonic subsidence analysis coupled with backstripping calculations based on data of newly interpreted sequence boundaries. Furthermore, burial and time plots were constructed in order to understand the burial and thermal history of the basin. Input data were based on facies, lithostratigraphic models and tectonic interpretations. The studied succession is up to 1000 m and is underlain by the Achaean Limpopo Mobile Belt. The subsidence within the basin supports the primary graben system which must have been centred within the present basins, and later became a region of faulting. The subsidence and burial history curves suggests two phases of rapid subsidence during the Early-Late Permian （300–230 Ma） and Middle Triassic （215–230 Ma）. The areas of greater extension subsided more rapidly during these intervals. Two slow subsidence phases are observed during the Late Triassic （215–198 Ma） and Early Jurassic （198–100 Ma）. These intervals represent the post-rift thermal subsidence and are interpreted as slow flexural subsidence. Based on these observations on the subsidence curves, it is possible to infer that the first stage of positive inflexion （300 Ma） is therefore recognised as the first stage of the Soutpansberg Basin formation.

关键词： Basin subsidence Karoo Supergroup Soutpansberg basin Permian-Jurassic

A 32-million year cycle detected in sea-level fluctuations over the last 545 Myr

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Geoscience Frontiers 2020年第6期11卷 2061-2065页

作者： Michael R.Rampino ken Caldeira Departments of Biology and Environmental Studies New York University100 Washington Square EastNew YorkNY10003USA NASA Goddard Institute for Space Studies2880 BroadwayNew YorkNY10025USA Department of Global Ecology Carnegie Institution for Science290 Panama StreetStanfordCA94305USA

Spectral analyses of past relative sea-level oscillations as represented by the ages of 57 Phanerozoic(the last 545 Myr)stratigraphic sequence boundaries from the Canadian Arctic show a strong spectral peak at 32 Myr(>99.9%confidence).These findings concur with previous reports of significant cycles with periods of around 30 Myr in various records of fluctuations of sea level,and in potentially related episodes of tectonism,volcanism,climate,and biotic *** boundaries commonly coincide with stage boundaries based on biostratigraphy,and are correlated with episodes of extinction and times of flood-basalt *** connection between tectonics and sea-level variations may come from changes in rates of ocean-floor spreading and subduction,intraplate stresses from plate-reorganizations,and pulsations of hotspot *** coordinated periodic fluctuations in tectonics,sea level and climate may be modulated by cyclical activity in the Earth’s mantle,although some pacing by astronomical cycles is suspected.

关键词： Sea level Periodicity Sequence boundary

Sufficient Conditions for Maximally Edge-Connected Hypergraphs

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Journal of the Operations Research Society of China 2021年第1期9卷 119-129页

作者： Lin-ken Tong Er-Fang Shan Department of Mathematics Shanghai UniversityShanghai 200444China School of Management Shanghai UniversityShanghai 200444China

The edge-connectivity of a graph or a hypergraph is defined as the minimum number of edges whose removal renders the graph or hypergraph disconnected.A graph or hypergraph is called maximally edge-connected if the edge-connectivity equals its minimum *** this paper,we show that some classical sufficient conditions for graphs to be maximally edge-connected can be generalized to hypergraphs.

关键词： Hypergraph Edge-connectivity Maximally edge-connected

Innovative technologies in manufacturing,mechanics and smart civil infrastructure

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International Journal of Smart and Nano Materials 2018年第4期9卷 261-278,I0003页

作者： ken P.Chong Songye Zhu Department of Mechanical&Aerospace Engineering George Washington UniversityWashingtonDCUSA Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHong Kong SARChina

An overview on converging technologies that are the primary drivers of the 4th Industrial Revolution is presented,followed by new developments in advanced manufacturing,nano-,information-technologies and smart civil infrastructure *** of these transformative technologies is *** are on advanced manufacturing,nano mechanics/materials,sensors,structural control,smart structures/materials,energy harvesting,multi-scale problems and simulation methods.

关键词： Nano-materials smart structures energy harvesting advanced manufacturing simulation and multi-scale problems

The Fabrication of Bio-ceramsite for the Removal of Heavy Metals and Its Toxicity to Bacteria

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Journal of Wuhan University of Technology(Materials Science) 2015年第3期30卷 649-654页

作者：石岩 SUN ken 齐学斌 GAO Qing Farmland Irrigation Research Institute Chinese Academy of Agricultural Sciences School of Environmental and Municipal Engineering North China University of Water Resources and Electric Power School of Water Resource & Environment China University of Geosciences

Bio-ceramsite technology is one of the most effective technologies in the pretreatment of drinking water. In this work, bio-ceramsite was fabricated by Citrobacterfreundii （C. freundii） immobilization on the ceramsite. The findings of the current study suggest that the bio-ceramites showed biosorption abilities for Cd（II） and Pb（II） and the removal efficiency for Pb（II） is lower than Cd（II）. The adsorption mechanism can be attributed to electrostatic attraction and covalent bond. The morphology of the cells changed after the adsorption of Cd（II） and Pb（II） due to the dissociation of the assembly of peptidoglycan and lipopolysaccharide. The fluorescence polarization has shown a significant decrease in membrane fluidity and an increase of permeability of cell membrane. The spectral profile of C. freundii suggests the alteration of carbonyl, amide and phosphonic groups on the cell membrane.

关键词： immobilization biosorption bio-ceramsite dissociation cell membrane

MEETING WITH THE GREEN URBAN PLANNER

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Journal of Green Building 2010年第1期5卷 36-40页

作者： ken Yeang Steffen Lehmann T.R.Hamzah and Yeang Kuala LumpurMalaysia University of Newcastle(Australia)

INTRODUCTION Malaysian architect *** Yeang is an architect-planner and is frequently described as one of the foremost eco-designers,theoreticians,and thinkers in the field of green *** has been described as one of the world’s leading advocates in ecological and passive low-energy *** has designed over one hundred projects,and his theory of“bio-climatic”towers has had an impact around the world,fusing high-tech with organic principles.

关键词： design. passive architect