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Serum matrix metalloproteinase 3 in detecting remitting seronegative symmetrical synovitis with pitting edema syndrome: A case report

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World Journal of Clinical Cases 2018年第5期6卷 84-87页

作者： Tsuneaki kenzaka ken Goda Department of Internal Medicine Hyogo Prefectural Kaibara Hospital Division of Community Medicine and Career Development Kobe University Graduate School of Medicine

We report a case of remitting seronegative symmetrical synovitis with pitting edema(RS3 PE) syndrome in a 71-year-old woman. She referred to our hospital with finger stiffness, edema of both hands and feet, pain of bilateral shoulder, wrist, metacarpophalangeal, proximal interphalangeal, and ankle joints. Rheumatoid factor was negative, human leukocyte antigen-B7 antigen was positive. Moreover, matrix metalloproteinase 3(MMP-3) was high. She was diagnosed with RS3 PE syndrome, and treatment with prednisolone(15 mg/d) was started. One week after prednisolone treatment initiation, CRP decreased to negative, and joint pain was almost completely resolved. However, hand stiffness persisted, and MMP-3 level was still high. Thus, prednisolone dose was increased to 20 mg/d, and the stiffness resolved. Twenty days after treatment initiation, MMP-3 was normalized. MMP-3 was more indicative of RS3 PE syndrome symptoms than CRP. Thus, MMP-3 seems to be more sensitive to RS3 PE syndrome symptoms.

关键词： Serum matrix metalloproteinase 3 Remitting seronegative symmetrical synovitis with pitting edema syndrome

Intensive chemotherapy and sequential hematopoietic stem cell transplantation:Is it necessary for high-risk T-cell lymphoblastic lymphoma?

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Cancer Communications 2021年第3期41卷 273-274页

作者： ken H.Young Division of Hematopathology Department of PathologyDuke University Medical CenterDuke University Cancer InstituteDurhamNC 27710USA

Adult T-cell lymphoblastic lymphoma(T-LBL)is characterized by its rarity and poor prognosis,however,it is currently being treated without any internationally recognized therapies[1].Acute lymphocytic leukemia(ALL)-like chemotherapy,such as the Berlin-Frankfurt-Muenster(BFM)regimen or the fractionated cyclophosphamide,vincristine,doxorubicin,and dexamethasone(hyperCVAD)regimen,is currently being widely used[2].

关键词： chemotherapy lymphoma lymphoblastic

Modeling on the shock wave in spheres hypervelocity impact on flat plates

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Defence Technology（防务技术） 2019年第4期15卷 457-466页

作者： ken Wen Xiao-Wei Chen De-Ning Di State Key Laboratory of Explosion Science and Technology Beijing Institute of Technology Beijing 100081 China Institute of Systems Engineering China Academy of Engineering Physics Mianyang Sichuan 621999 China Advanced Research Institute of Multidisciplinary Science Beijing Institute of Technology Beijing 100081 China

In hypervelocity impacts of projectiles into thin flat targets,shock initiation and interaction dominate the responses of projectiles and targets,and especially dominate the features of the debris *** estimate the geometric features of the wave front during the first complete propagation in the sphericalprojectile,the Geometric Propagation Model(GPM)is built in this paper to describe the geometry of the shock wave front,which proposes an ellipse contour as a function of time and equivalent *** GPM identifies the geometric features of the wave front as a function of time and impact velocity *** with the GPM and SPH simulation,the shock pressure distribution and attenuation in the spherical-projectile have been ***,the attenuation of shock pressure and speed are presented as a function of impact velocity,respectively,and a method for obtaining the equivalent speed of the shock wave is proposed by the *** GPM may be applicable to hypervelocity events involving any monolithic materials as long as the equivalent speed could be supplied from numerical *** GPM proposed in this paper and the corresponding shock wave analysis provide a new insight into the processes of the quantitative analysis of the initiation of the debris cloud.

关键词： Hypervelocity impact Shock wave Numerical simulation Debris cloud formation

Numerical Study for Hysteresis Phenomena of Shock Wave Reflection in Overexpanded Axisymmetric Supersonic Jet

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Journal of Thermal Science 2006年第3期15卷 220-225页

作者： Tsuyoshi Yasunobu ken Matsuoka Hideo Kashimura ShigeruMatsuo ToshiakiSetoguchi Corresponding Author Department of Control and Information Systems EngineeringKitakyushuCollege of Technology5-20-1 ShiiKokuraminamiKitakyushuJapan Kitakyushu College of Technology 5-20-1 ShiiKokuraminamiKitakyushuJapan(Student) Kitakyushu College of Technology 5-20-1 ShiiKokuraminamiKitakyushuJapan Department of Mechanical Engineering Saga University1HonjoSagaJapan

When the high-pressure gas is exhausted to the vacuum chamber from the supersonic nozzle, the overexpanded supersonic jet is formed at specific condition. In two-dimensional supersonic jet, furthermore, it is known that the hysteresis phenomena for the reflection type of shock wave in the flow field is occurred under the quasi-steady flow and for instance, the transitional pressure ratio between the regular reflection （RR） and Mach reflection （MR） is affected by this phenomenon. Many papers have described the hysteresis phenomena for underexpanded supersonic jet, but this phenomenon under the overexpanded axisymmetric jet has not been detailed in the past papers. The purpose of this study is to clear the hysteresis phenomena for the reflection type of shock wave at the overexpanded axisymmetric jet using the TVD method and to discuss the characteristic of hysteresis phenomena.

关键词： compressible flow axisymmetric flow supersonic jet regular reflection Mach reflection

The deterministic condition for the ground reaction force acting point on the combined knee valgus and tibial internal rotation moments in early phase of cutting maneuvers in female athletes

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Journal of Sport and Health Science 2024年第3期13卷 376-386页

作者： Issei Ogasawara ken Ohta Gajanan S.Revankar Shoji Konda Yohei Shimokochi Hideyuki Koga ken Nakata Department of Health and Sport Sciences Graduate School of MedicineOsaka UniversityToyonaka 560-0043Japan Sports Sensing Co. LTD.Fukuoka 815-0035Japan Department of Neurology Graduate School of MedicineOsaka UniversitySuita 565-0871Japan Department of Health and Sport Management Osaka University of Health and Sport SciencesSennan-gun 590-0496Japan Department of Joint Surgery and Sports Medicine Graduate School of Medical and Dental SciencesTokyo Medical and Dental UniversityBunkyo-ku 113-8519Japan

Background:Combined knee valgus and tibial internal rotation(VL+IR)moments have been shown to stress the anterior cruciate ligament(ACL)in several in vitro cadaveric *** utilize this knowledge for non-contact ACL injury prevention in sports,it is necessary to elucidate how the ground reaction force(GRF)acting point(center of pressure(CoP))in the stance foot produces combined knee VL+IR moments in risky maneuvers,such as ***,the effects of the GRF acting point on the development of the combined knee VL+IR moment in cutting are still ***:We first established the deterministic mechanical condition that the CoP position relative to the tibial rotational axis differentiates the GRF vector’s directional probability for developing the combined knee VL+IR moment,and theoretically predicted that when the CoP is posterior to the tibial rotational axis,the GRF vector is more likely to produce the combined knee VL+IR moment than when the CoP is anterior to the tibial rotational ***,we tested a stochastic aspect of our theory in a lab-controlled in vivo *** females performed 60˚cutting under forefoot/rearfoot strike conditions(10 trials each).The positions of lower limb markers and GRF data were measured,and the knee moment due to GRF vector was *** trials were divided into anterior-and posterior-CoP groups depending on the CoP position relative to the tibial rotational axis at each 10 ms interval from 0 to 100 ms after foot strike,and the occurrence rate of the combined knee VL+IR moment was compared between trial ***:The posterior-CoP group showed significantly higher occurrence rates of the combined knee VL+IR moment(maximum of 82.8%)at every time point than those of the anterior-CoP trials,as theoretically predicted by the deterministic mechanical ***:The rearfoot strikes inducing the posterior CoP should be avoided to reduce the risk of non-contact ACL injury associated with the com

关键词： Center of pressure Deterministic condition Foot strike pattern Injury mechanism Moment of ground reaction force

Toward a typology of sustainability for cities

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Journal of Traffic and Transportation Engineering(English Edition) 2014年第3期1卷 180-195页

作者： ken Doust Windana Research Pty Ltd & Research Centre for Integrated Transport Innovation(rCITI) University of New South WalesSydneyAustralia

Sustainability responses must accelerate to avoid major risks to cities. Climate change impact on cities, likely to be significant if global sustainability initiatives are not quickened, is a paramount example of the risk. World wide meetings of city planning practitioners and researchers agree that an urgent agenda is to work together to empower cities and their governments with funds, tools and mentoring to make the responses needed. In the spirit of this urgent agenda, this paper introduces some prac- tical methods for assessing sustainability associated with transport and urban form in our cities. A concept of strategic scans of future scenarios, which underpins the backcasting approach, has been introduced at the 12th World Conference on Transport Research（WCTR） in 2010 and has broken urban and transport planning trend. These strategic scans are based on a sustainability framework, the elements of which provide evidence based drivers of sustainability. The framework culminates in metric visualisations for each of the three pillars of sustainability. The paper details some of the operational aspects of these metrics in the form of environmental sustainability-accessibility space, putting into practice measures of environmental stewardship, social equity, economic efficiency, and the relationship among them. The paper concludes with a call of developing a typology of sustainability performance using the strategic scan methodology to extend the principles of the methodology into a useful tool for city governments and contribute to assembling a database of city forms, transport structures, and their sustainability performances.

关键词： transport sustainability cities backcasting climate change metrics

Efficacy and safety of stellate ganglion block in chronic ulcerative colitis

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World Journal of Gastroenterology 2017年第17期23卷 3193-3194页

作者： Eugene Lipov ken Candido department of anesthesiology advocate illinois masonic medical center

Sympathetic system modulation by stellate ganglion blockade may modulate immune dysfunction and significantly improve symptoms of chronic ulcerative colitis.

关键词： Stellate ganglion block Ulcerative colitis Immune function Chronic ulcerative colitis

Connecting Concepts of Cultural Landscape and Historic Urban Landscape: The Politics of Similarity

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Built Heritage 2018年第3期2卷 53-67页

作者： ken Taylor College of Arts and Social Sciences Australian National UnivesityCanberraAustralia

This paper projects the concept of cultural landscapes into the realm of urban conservation in the context of the Historic Urban Landscape(HUL)*** do this I take an historical overview of how,during the latter half of the 1980s and early 1990s,academic and professional interest in heritage studies started to embrace the cultural landscape *** movement continued through the 2000s with increasing links between theory and practice on urban conservation concerns and the concept of cities as cultural *** this connection the move in 2011 by UNESCO with the Recommendation on the Historic Urban Landscape is particularly *** were two significant *** was increasing questioning of heritage as focusing narrowly on the monuments and sites *** has been the growing appreciation that urban conservation locking onto separate historic towns or specific parts of cities is counter-productive;it ignores towns and cities as holistic entities isolating historic areas virtually as museum pieces separate from the rest of the urban fabric and lacking *** contrast HUL with its landscape approach is a process1 that embraces-city-wide-cultural,natural,tangible and intangible,social,economic,visual and experiential aspects of the physical morphology of the city and the image of the city;it underpins the fundamental concept of urban areas as a series of layers through time that link past,present and future as in the construct of cultural landscape.

关键词： cultural landscape urban conservation historic urban landscape heritagisation charters values communities

Correlation of the largest craters,stratigraphic impact signatures,and extinction events over the past 250 Myr

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Geoscience Frontiers 2017年第6期8卷 1241-1245页

作者： Michael R.Rampino ken Caldeira Department of Biology New York University100 Washington Square EastNew YorkNY 10003USA NASA Goddard Institute for Space Studies2880 BroadwayNew YorkNY 10025USA Carnegie Institute for Science Department of Global Ecology260 Panama St.StanfordCA 94305USA

The six largest known impact craters of the last 250 Myr(≥70 km in diameter),which are capable of causing significant environmental damage,coincide with four times of recognized extinction events at 36(with 2 craters),66,and 145 Myr ago,and possibly with two provisional extinction events at 168 and215 Myr *** impact cratering events are accompanied by layers in the geologic record interpreted as impact *** occurrences of impacts and extinctions can be rejected at confidence levels of99.96%(for 4 impact/extinctions)to 99.99%(for 6 impact/extinctions).These results argue that several extinction events over the last 250 Myr may be related to the effects of large-body impacts.

关键词： Extinctions Impact craters Ejecta layers