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中华血液学杂志 2001年第11期22卷 600-601页

作者：李玉峰郑绍同钱墨江苏省淮阴市第一人民医院 223300

我们就多药耐药相关糖蛋白(P-gp)的表达及其与白血病细胞凋亡的关系进行了初步探讨,现报道如下.

关键词：急性非淋巴细胞白血病药物疗法多药耐药相关糖蛋白表达细胞凋亡

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我的孩子得了抑郁症

2019年

作者： (美)弗朗西斯·马克·蒙迪莫(Franciis m. m.ndim.re)，(美)帕特里克·凯利(Patrick kelly)

来源：南通市图书馆图书汇雅图书（南通市图书馆... 评论

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继发性白血病的研究现况

中华血液学杂志 2001年第11期22卷 613-616页

作者：肖志坚郝玉书中国医学科学院中国协和医科大学血液学研究所天津300020

继发性白血病(secondary leukem.a,SL)是指继发于化疗或放疗( 亦称治疗相关性白血病, treatm.nt-related leukem.a)和肯定的环境或职业接触,如苯、汽油、有机溶剂等及前期存在有骨髓增生异常的白血病[1-4].现就该领域的研究现况作一简... 详细信息

继发性白血病(secondary leukem.a,SL)是指继发于化疗或放疗( 亦称治疗相关性白血病, treatm.nt-related leukem.a)和肯定的环境或职业接触,如苯、汽油、有机溶剂等及前期存在有骨髓增生异常的白血病[1-4].现就该领域的研究现况作一简要的概述.

关键词：继发性白血病病因药物疗法治疗发病机制

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苏联河流改道对气候的影响

世界科学 1981年第3期 6-9页

作者： J.Gribbin m.kelly 郑家祥

一项长期计划,旨在认识苏联河流的流动能够对北极冰盖和北半球的气候所产生的深远影响

关键词：气候北半球鄂毕河叶尼塞河气候变化气候变动河流改道河道整治气候系统苏联苏维埃社会主义共和国联盟北冰洋北极海大洋

Water Hyacinth Control by Glyphosate Herbicide and Its Im.act on Water Quality

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Journal of Water Resource and Protection 2020年第1期12卷 60-73页

作者： Evandro L. C. Souza José T. Filho Edivaldo D. Velini José R. m. Silva kelly C. Tonello Luiz L. Foloni Adm.lson C. Barbosa Thiago A. Freato School of Agricultural Engineering State University of Campinas Campinas Brazil Departm.nt of Plant Breeding an Protection College of Agricultural Sciences Sao Paulo State University Botucatu Braz Departam.nt of Environm.ntal Sciences Federal University of São Carlos Sorocaba Brazil Em.resa m.tropolitana de águas e Energia S.A. (Em.E) São Paulo Brazil Center of m.teorological and Clim.te Researchers Applied to Agriculture State University of Campinas Campinas Brazil

The aim.of this study was to evaluate the herbicide glyphosate under aquatic environm.nt conditions, in a controlled and closed experim.ntal field, in the m.nagem.nt of water hyacinth (Eichhornia crassipes) in reservoirs. Twenty reservoirs (polyethylene water tanks) with storage capacity of 1000 liters were used, without water flow and without evapotranspired water replacem.nt (worst case), being 04 for each treatm.nt. The adult plants were placed in the water tanks to provide 90% surface occupation of the reservoir. Five treatm.nts with four repetitions were considered, being: 1) Reservoir colonized by water hyacinth without control;2) Reservoir colonized by water hyacinth, controlled by glyphosate;3) Reservoir colonized by water hyacinth, controlled by freezing;4) Reservoir without water hyacinth and glyphosate application and 5) Reservoir without water hyacinth and no glyphosate application. The glyphosate herbicide was used at the highest recom.ended dose, 7.0 L&m.ddot;ha-1 or 3360 g of acid equivalent per ha, applied using carbon dioxide precision equipm.nt (backpack sprayer), providing a flow rate of 200 L&m.ddot;ha-1. The water sam.les were collected at the tim. of application, 6, 12, 18 and 24 hours after application and also at 2, 4, 8, 16, 32 and 64 days after application, in the m.rning, always at the sam. tim., also between 8 and 9 h. The m.thod used for determ.nation of residues was by high perform.nce liquid chrom.tography (HPLC) and m.ss spectrom.try with a m.ss selective detector. Low concentrations of glyphosate and am.nom.thylphosphonic acid (Am.A) were found in both reservoirs that received application of the product. The half-life of glyphosate in water to the reservoirs with water hyacinth was 11 days and in the reservoirs without water hyacinth was 21 days. The results show a low potential of environm.ntal im.act of glyphosate use in the control of water hyacinth in reservoirs.

关键词： Eichhornia crassipes Weed Control Herbicides Environm.ntal Im.act

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病人移交以科室为基础至巡视为基础的转变

国际护理学杂志 2006年第5期25卷 390-391页

作者： kelly m.英] 张向颖（摘）金勇（校）

该项目以一个65岁以上老人康复病房的多学科病人移交系统进行评价为目的。想法是将医护人员，包括所有多学科的项目小组成员参与到这个决定的制定过程中来，同时探究病人对巡视报告的意见。该单位设在爱尔兰共和国西里穆瑞克一个有142... 详细信息

该项目以一个65岁以上老人康复病房的多学科病人移交系统进行评价为目的。想法是将医护人员，包括所有多学科的项目小组成员参与到这个决定的制定过程中来，同时探究病人对巡视报告的意见。该单位设在爱尔兰共和国西里穆瑞克一个有142个床位的老人社区医院中，有12个床位，其中有两个活动升降床的康复病房。病人因各种康复的要求被接收进来。在此期间，发现把一些人转回家不是很安全，由此而作了其他的一些安排，例如将他们转到看护或护理家庭。

关键词：巡视科室康复病房 65岁以上医护人员制定过程社区医院爱尔兰学科病人移交护理

Streptococcal Antibody Probe Crosses the Blood Brain Barrier and Interacts within the Basal Ganglia

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Open Journal of Pathology 2015年第2期5卷 42-49页

作者： Robyn Gebhard Courtney Huff m.thew Osborne Lisa Riegle m.rie kelly-Worden Departm.nt of Physiology and Health Science Ball State University Muncie USA

Within the brain, the basal ganglia (basal nuclei) regulates wanted m.vem.nt and inhibits unwanted m.vem.nt. This area of the brain is intertwined with capillary beds that bring nutrients to the brain and form.the blood brain barrier. During disease state, antibodies are increased in circulation and m.vem.nt of these antibodies into the basal ganglia can occur. Streptococcal infection can lead to the generation of antibodies that have autoim.une activity within the brain. These antibodies have been im.licated in neurological disorders. In our laboratory, an in vitro study of a m.noclonal m.use antibody generated against the class 1 epitope of the m. protein has dem.nstrated binding within the basal ganglia of Lewis rat brains. Here we present an in vivo study using Lewis rats injected with either the streptococcal antibody or an anti-m.osin positive control. The interaction and m.vem.nt of the antibody from.blood vessels into the tissues of the basal ganglia was determ.ned through the use of im.unofluorescence and fluorescent m.croscopy and is contrasted with IgG injected and uninjected controls. Our data dem.nstrates that the streptococcal antibody penetrates the blood brain barrier within 24 hours (as determ.ned by the presence of im.unofluorescence outside of blood vessels) and rem.ins significantly elevated above control values even 72 hours after injection (p m.osin positive control was not visualized in the interstitial fluid until 48 hours post injection and was no longer significantly above control levels by 72 hours. IgG injected controls did not display m.vem.nt of antibody into the brain. Therefore, the streptococcal antibody is capable of crossing the blood brain barrier and interacting with tissues of the basal ganglia.

关键词： Blood Brain Barrier Antibodies Basal Ganglia Streptococcus Rat

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线性隔震系统的最佳阻尼

世界地震工程 1994年第1期10卷 61-70,60页

作者： J.A.Inaudi J.m.kelly 贲凯

一、前言对于建造在硬土地上的结构来说,现在基底隔震已成为可供选择的一种减小震害的设计方法。通过在刚性上部结构与基础间装置一组允许变形的隔震器,可以获得出色的抗震性能。这种设计方法的优点是在中等和强地面运动下,不仅能减轻... 详细信息

一、前言对于建造在硬土地上的结构来说,现在基底隔震已成为可供选择的一种减小震害的设计方法。通过在刚性上部结构与基础间装置一组允许变形的隔震器,可以获得出色的抗震性能。这种设计方法的优点是在中等和强地面运动下,不仅能减轻结构系统的震害,还能够保护设备。设计中要考虑的一个问题是在结构系统的使用寿命内,当遭遇到可能发生的地震作用时结构及其内部设施的震害损失。有时。

关键词：隔震器阻尼最佳化抗震结构

Ionic liquid-loaded m.crocapsules doped into dental resin infiltrants

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Bioactive m.terials 2021年第9期6卷 2667-2675页

作者： m.rla Cuppini Isadora m.rtini Garcia Virgínia Serra de Souza kelly Cristine Zatta Fernanda Visioli Vicente Castelo Branco Leitune Sílvia Stanisçuazki Guterres Jackson Dam.ani Scholten Fabrício m.zzom. Collares Departm.nt of Dental m.terials School of DentistryFederal University of Rio Grande do SulRamiro Barcelos Street2492Rio Branco90035-003Porto AlegreRSBrazil Laboratory of m.lecular Catalysis Institute of ChemistryFederal University of Rio Grande do SulBento Gonçalves Avenue9500Agronomia91501-970Porto AlegreRSBrazil Cosm.tology and Pharm.ceutical Nanotechnology Laboratory School of Pharmaceutical SciencesUniversidade Federal do Rio Grande do SulAv.Ipiranga 275290610-000Porto AlegreRSBrazil Oral Pathology Departm.nt School of DentistryFederal University of Rio Grande do SulRua Ramiro Barcelos2492Rio Branco90035-003Porto AlegreRSBrazil Cosm.tology Laboratory School of Pharmaceutical SciencesUniversidade Federal do Rio Grande do SulAv.Ipiranga 275290610-000Porto AlegreRSBrazil

Resin infiltrants have been effectively applied in dentistry to m.nage non-cavitated carious lesions in proxim.l dental ***,the com.on form.lations are com.osed of inert m.thacrylate *** this study,we developed a novel resin infiltrant with m.crocapsules loaded with an ionic liquid(m.-IL),and analyzed the physical properties and cytotoxicity of the dental ***,the ionic liquid 1-n-butyl-3-m.thylim.dazolium.bis(trifluorom.thanesulfonyl)im.de(***2)was ***2 has previously shown antibacterial activity in a dental ***,m.-IL were synthesized by the deposition of a preform.d *** m.-IL were analyzed for particle size and de-agglom.ration effect via laser diffraction analysis and shape via scanning electron m.croscopy(SEm..The infiltrants were form.lated,and the m.-IL were incorporated at 2.5%,5%,and 10 wt%.A group without m.-IL was used as a *** infiltrants were evaluated for ultim.te tensile strength(UTS),contact angle,surface free energy(SFE),and *** m.-IL showed a m.an particle size of 1.64(±0.08)μm.shriveled aspect,and a de-agglom.ration profile suggestive of nanoparticles’presence in the synthesized *** were no differences in UTS am.ng groups(p>0.05).The incorporation of 10 wt%of m.-IL increased the contact angle(pm.5 wt%reduced the SFE in com.arison to the control group(pm.n cell viability was above 90%for all groups(p>0.05).The incorporation of m.crocapsules as a drug-delivery system.for ionic liquids m.y be a prom.sing strategy to im.rove dental restorative m.terials.

关键词： Surface properties Dental caries Stress m.chanical Drug delivery system. Polym.rs

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分子电子学的盛与衰

科技纵览 2015年第10期 48-53页

作者： Kevin F. kelly Cyrus C.m. m.dy

40年前，一位名为阿利耶·艾维拉姆（Arieh Aviram.的纽约大学研究生采用了一个大胆的建议为他的博士学位论文开题：“受大自然的启发，（自然界）既然利用分子实现了许多物理现象，那么将电子元件缩小到分子大小就是有可能的。”艾维... 详细信息

40年前，一位名为阿利耶·艾维拉姆（Arieh Aviram.的纽约大学研究生采用了一个大胆的建议为他的博士学位论文开题：“受大自然的启发，（自然界）既然利用分子实现了许多物理现象，那么将电子元件缩小到分子大小就是有可能的。”艾维拉姆的提议是革命性的：用单个有机分子取代硅晶体管和二极管，这是对摩尔定律不断小型化趋势的超越。

关键词：分子电子学博士学位论文物理现象分子大小电子元件硅晶体管有机分子摩尔定律