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Tropical cyclogenesis:Controlling factors and physical mechanisms

Tropical Cyclone Research and Review 2023年第3期12卷 165-181页

作者： V.P.m.Rajasree Xi Cao Hamish Ramsay kelly m.nú~nez ocasio Gerard Kilroy George R.Alvey III m.nhee Chang Chaehyeon Chelsea nam Hironori Fudeyasu Hsu-Feng Teng Hui Yu India meteorological Departm.nt GoaIndia Chinese Academy of Sciences BeijingChina CSIRO EnvironmentAspendaleVictoriaAustralia national Center for Atmospheric Research ColoradoUSA Institut f¨ur Physik der Atmosph¨are Deutsches Zentrum f¨ur Luft-undBerlinGermany Cooperative Institute for marine and Atmospheric Studies University of MiamiMiamiFloridaUSA nOAA/Atlantic Oceanographic and meteorological Laboratory/Hurricane Research Division MiamiFloridaUSA Korea Institute of Science and Technology SeoulRepublic of Korea Colorado State University ColoradoUSA Yokohama national University YokohamaJapan national Center for Atmospheric Research/Pacific Science Association ColoradoUSA Shanghai Typhoon Institute/China meteorological Adm.nistration ShanghaiChina

In this review,advances in the understanding of the controlling factors and physical mechanisms of tropical cyclogenesis(TCG)are summarized from recent(2018–2022)research on TCG,as presented in the Tenth International Workshop on Tropical Cyclones(IWTC-10).Observational,theoretical,and numerical modeling studies published in recent years have advanced our knowledge on the influence of large-scale environm.ntal factors on ***,studies have shown clearly that appropriate convective coupling with tropical equatorial waves enhances the developm.nt chances of *** recently,illum.nating research has been carried out on analyzing the mechanisms by which oscillations and teleconnections(El ni˜no Southern Oscillation(EnSO)in particular)modulate TCG globally,in association with changes in the sea surface temperature(SST).In addition to this,recent research has diligently addressed different aspects of *** studies have reported the applicability of unified theories and physical mechanisms of TCG in different ocean ***,research has been carried out on TCG under different flow pattern regimes,dry air intrusion,importance of marsupial pouch,genesis of medicanes,wind shear,convection and vertical ***,studies have discussed the possibility of near equatorial TCG provided that there is enough supply of background vertical vorticity and relatively low vertical wind *** has been made to understand the role of climate change on global and regional ***,there are still significant gaps which need to be addressed in order to better understand TCG prediction.

关键词： Tropical cyclogenesis AEW EnSO SST marsupial pouch Dry air intrusion moderate shear Convection near equatorial TCG Climate change

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Kinetics of glyphosate and am.nomethylphosphonic acid sorption onto m.ntmorillonite clays in soil and their translocation to genetically modified corn

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Journal of Environm.ntal Sciences 2024年第1期135卷 669-680页

作者： meichen Wang kelly J Rivenbark Timothy D Phillips Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical SciencesTexas A&M UniversityTX 77845USA

The co-occurrence of glyphosate(GLP)and am.nomethylphosphonic acid(AmPA)in contam.nated water,soil,sedim.nt and plants is a cause for concern due to potential threats to the ecosystem and hum.n health.A major route of exposure is through contact with contam.nated soil and consumption of crops containing GLP and AmPA ***,clay-based sorption strategies for mixtures of GLP and AmPA in soil,plants and garden produce have been very *** this study,in vitro soil and in vivo genetically modified corn models were used to establish the proof of concept that the inclusion of clay sorbents in contam.nated soils will reduce the bioavailability of GLP and AmPA in soils and their adverse effects on plant *** of chemical concentration(1–10 mg/kg),sorbent dose(0.5%-3%in soil and 0.5%-1%in plants)and duration(up to 28 days)on sorption kinetics were *** time course results showed a continuous GLP degradation to *** inclusion of calcium m.ntmorillonite(Cm)and acid processed m.ntmorillonite(APm)clays at all doses significantly and consistently reduced the bioavailability of both chemicals from soils to plant roots and leaves in a dose-and time-dependent m.nner without detectable *** treated with 0.5%and 1%APm inclusion showed the highest growth rate(p≤0.05)and lowest chemical bioavailability with up to 76%reduction in roots and57%reduction in *** indicated that m.ntmorillonite clays could be added as soil supplem.nts to reduce hazardous mixtures of GLP and AmPA in soils and plants.

关键词： Glyphosate AmPA Adsorption Soil remediation Plant Hydroponic system

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A rat model of multicompartm.ntal traumatic injury and hemorrhagic shock induces bone marrow dysfunction and profound anemia

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Animal models and Experim.ntal medicine 2024年第3期7卷 367-376页

作者： Lauren S.kelly Jennifer A.m.nley Erick E.Pons Kolenkode B.Kannan Elizabeth m.Whitley Letitia E.Bible Philip A.Efron Alicia m.mohr Departm.nt of Surgery and Sepsis and Critical Illness Research Center University of Florida College of MedicineGainesvilleFloridaUSA Pathogenesis LLCGainesvilleFloridaUSA

Background:Severe trauma is associated with systemic inflammation and organ *** rodent trauma models are the mainstay of postinjury research but have been criticized for not fully replicating severe hum.n *** aim of this study was to create a rat model of multicompartm.ntal injury which recreates profound traumatic ***:male Sprague-Dawley rats were subjected to unilateral lung contusion and hemorrhagic shock(LCHS),multicompartm.ntal polytrauma(PT)(unilateral lung contusion,hemorrhagic shock,cecectomy,bifemoral pseudofracture),or na?ve ***,plasma toll-l ike receptor 4(TLR4),hemoglobin,spleen to body weight ratio,bone marrow(Bm)erythroid progenitor(CFU-GEmm,BFU-E,and CFU-E)growth,plasma granulocyte colony-stimulating factor(G-CSF)and right lung histologic injury were assessed on day 7,with significance defined as p valuesma resulted in markedly more profound inhibition of weight gain compared to LCHS(p=0.0002)along with elevated plasma TLR4(pmoglobin(pnd enlarged spleen to body weight ratios(p=0.004).Both LCHS and PT dem.nstrated suppression of CFU-E and BFU-E growth compared to naive(pma G-CSF was elevated in PT compared to both na?ve and LCHS(pnd PT dem.nstrated significant histologic right lung injury with poor alveolar wall integrity and interstitial ***:multicompartm.ntal injury as described here establishes a reproducible model of multicompartm.ntal injury with worsened anemia,splenic tissue enlargem.nt,weight loss,and increased inflammatory activity compared to a less severe *** may serve as a more effective model to recreate profound traumatic injury to replicate the hum.n inflammatory response postinjury.

关键词： anemia i nflammation polytrauma pseudofracture shock

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Genome and clonal hematopoiesis stability contrasts with imm.ne,cfDnA,mitochondrial,and telomere length changes during short duration spaceflight

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Precision Clinical medicine 2024年第1期7卷 1-13页

作者： J.Sebastian Garcia-medina Karolina Sienkiewicz S.Anand narayanan Eliah G.Overbey Kirill Grigorev Krista A.Ryon marissa Burke Jacqueline Proszynski Braden Tierney Caleb m.Schmidt nuria m.ncia-Trinchant Remi Klotz Veronica Ortiz Jonathan Foox Christopher Chin Deena najjar Irina matei Irenaeus Chan Carlos Cruchaga Ashley Kleinm.n JangKeun Kim Alexander Lucaci Conor Loy Omary mzava Iwijn De Vlam.nck Anvita Singaraju Lynn E.Taylor Julian C.Schmidt michael A.Schmidt kelly Blease Juan moreno Andrew Boddicker Junhua Zhao Bryan Lajoie Andrew Altomare Semyon Kruglyak Shawn Levy m.n Yu Duane C.Hassane Susan m.Bailey kelly Bolton Jaime mateus Christopher E.mason Departm.nt of Physiology and Biophysics Weill Cornell MedicineCornell UniversityNew YorkNY 10021USA The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine Weill Cornell MedicineNew YorkNY 10021USA Departm.nt of Imm.nology Weill Cornell MedicineCornell UniversityNew YorkNY 10021USA Departm.nt of Stem Cell Biology and Regenerative medicine Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCA 90033USA Space Exploration Technologies Corporation HawthomeCA 90250USA Sovaris Aerospace BoulderCO 80302USA Advanced Pattern Analysis&Hum.n Perform.nce Group BoulderCO 80302USA Children's Cancer and Blood Foundation Laboratories Departments of Pediatrics and Cell and Developmental BiologyDrukier Institute for Children's HealthMeyer Cancer CenterWeill Cornell MedicineNew YorkNY 10021USA meyer Cancer Center Weill Cornell MedicineNew YorkNY 10065USA Departm.nt of nutrition and Integrative Physiology Florida State UniversityTallahasseeFL 32306USA Departm.nt of Systems Engineering Colorado State UniversityFort CollinsCO 80523USA Elem.nt Biosciences San DiegoCA 10055USA Departm.nt of Environm.ntal and Radiological Health Sciences Colorado State UniversityFort CollinsCO 80523USA Cell and molecular Biology Program Colorado State UniversityFort CollinsCO 80523USA BioAstra Inc New YorkNYUSA Washington University St Louis Oncology Division St.LouisMO 63100USA meinig School of Biomedical Engineering Cornell UniversityIthacaNY 14853USA The Feil Family Brain and m.nd Research Institute Weill Cornell MedicineNY 10021USA WorldQuant Initiative for Quantitative Prediction Weill Cornell MedicineNew YorkNY 10021USA

Background The Inspiration4(I4)mission,the first all-civilian orbital flight mission,investigated the physiological effects of short-duration spaceflight through a multi-omic *** advances,there remains much to learn about hum.n adaptation to spaceflight's unique challenges,including microgravity,imm.ne system perturbations,and radiation *** To provide a detailed genetics analysis of the mission,we collected dried blood spots pre-,during,and post-flight for DnA *** length was measured by quantitative PCR,while whole genome and cfDnA sequencing provided insight into genomic stability and imm.ne adaptations.A robust bioinformatic pipeline was used for data analysis,including variant calling to assess mutational *** Telomere elongation occurred during spaceflight and shortened after return to ***-free DnA analysis revealed increased imm.ne cell signatures *** significant clonal hematopoiesis of indeterm.nate potential(CHIP)or whole-genome instability was *** long-term gene expression changes across imm.ne cells suggested cellular adaptations to the space environm.nt persisting m.nths *** Our findings provide valuable insights into the physiological consequences of short-duration spaceflight,with telomere dynamics and imm.ne cell gene expression adapting to spaceflight and persisting after return to *** sequencing data will serve as a reference point for studying the early developm.nt of CHIP in astronauts,an understudied phenom.non as previous studies have focused on career *** study will serve as a reference point for future commercial and non-commercial spaceflight,low Earth orbit(LEO)missions,and deep-space exploration.

关键词： genomes clonal hematopoiesis stability imm.ne mitochondria ribosomes spaceflight

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Elucidating regulatory processes of intense physical activity by multi-omics analysis

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military medical Research 2024年第4期 479-499页

作者： Ernesto S.nakayasu marina A.Gritsenko Young-mo Kim Jennifer E.Kyle kelly G.Stratton Carrie D.nicora nathalie m.noz Kathleen m. navarro Daniel Claborne Yuqian Gao Karl K.Weitz Vanessa L. Paurus Kent J. Bloodsworth Kelsey A. Allen Lisa m. Bramer Fernando m.ntes Kathleen A. Clark Grant Tietje Justin Teeguarden Kristin E.Burnum-Johnson Biological Sciences Division Pacific Northwest National Laboratory Environm.ntal and molecular Sciences Division Pacific Northwest National Laboratory Centers for Disease Control and Prevention National Institute for Occupational Safety and Health Western States Division Computational Analytics Division Pacific Northwest National Laboratory national Security Directorate Pacific Northwest National Laboratory Los Angeles County Fire Departm.nt Centers for Disease Control and Prevention National Institute for Occupational Safety and Health Respiratory Health Division Environm.ntal and molecular Toxicology Oregon State University

Background: Physiological and biochemical processes across tissues of the body are regulated in response to the high dem.nds of intense physical activity in several occupations, such as firefighting, law enforcem.nt, military, and sports. A better understanding of such processes can ultimately help improve hum.n perform.nce and prevent illnesses in the work ***: To study regulatory processes in intense physical activity simulating real-life conditions, we performed a multi-omics analysis of 3 biofluids(blood plasma, urine, and saliva) collected from 11 wildland firefighters before and after a 45 m.n, intense exercise regim.n. Omics profiles post-vs. pre-exercise were compared by Student's t-test followed by pathway analysis and comparison between the different omics ***: Our multi-omics analysis identified and quantified 3835 proteins, 730 lipids and 182 metabolites combining the 3 different types of samples. The blood plasma analysis revealed signatures of tissue damage and acute repair response accompanied by enhanced carbon metabolism to meet energy dem.nds. The urine analysis showed a strong, concomitant regulation of 6 out of 8 identified proteins from the renin-angiotensin system supporting increased excretion of catabolites, reabsorption of nutrients and maintenance of fluid balance. In saliva, we observed a decrease in 3 pro-inflammatory cytokines and an increase in 8 antimicrobial peptides. A systematic literature review identified 6 papers that support an altered susceptibility to respiratory ***: This study shows simultaneous regulatory signatures in biofluids indicative of homeostatic maintenance during intense physical activity with possible effects on increased infection susceptibility, suggesting that caution against respiratory diseases could benefit workers on highly physical dem.nding jobs.

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国际护理知识网络建设的调查研究

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International Journal of nursing Sciences 2024年第3期11卷 374-380,I0004,I0005页

作者： margareth Santos Zanchetta Suzanne Fredericks Kateryna metersky Geraldine martorella Pammla Petrucka Laurie Clune kelly Graziani Giacchero Vedana Cristina Rosa Soares Lavareda Baixinho Cristianne maria Famer Rocha Sara Campagna Sally Zhang He márcia Teles de Oliveira Gouveia marcelo medeiros Denize Bouttelet m.nari Daniel Gonzalo Eslava Albarracin Carlos Aguilera-Serrano Walterlania Silva Santos Toronto metropolitan University TorontoCanada Florida State University TallahasseeUSA University of Saskatchewan ReginaCanada University of Regina ReginaCanada State of Sao Paulo University Ribeirao PretoBrazil Lisbon Superior School of nursing LisbonPortugal Federal University of Rio Grande do Sul Porto AlegreBrazil University of Turin TurinItaly Scarborough Health network ScarboroughCanada Federal University of Piauí TeresinaBrazil Federal University of Goias GoianiaBrazil Fundacion Universitaria Cafam BogotaColombia University of malaga MalagaSpain University of Brasília Ceil^andiaBrazil

本文报告了为创建护理知识网络(nursing Knowledge network,nKn)对不同国家护理院校进行环境扫描调查所收集到的信息。采用在线方式(2021年2-10月)进行环境扫描,探索研究领域的确定、现有资源、预期收益、教学研究创新、知识传播障碍及... 详细信息

本文报告了为创建护理知识网络(nursing Knowledge network,nKn)对不同国家护理院校进行环境扫描调查所收集到的信息。采用在线方式(2021年2-10月)进行环境扫描,探索研究领域的确定、现有资源、预期收益、教学研究创新、知识传播障碍及网络的预期贡献。目标信息提供者包括来自13个国家63所大学的200名护理教师。要求每所大学有1名参与者回答问卷。共有42所大学(约70%)回复,包括巴西21所,加拿大4所,葡萄牙和西班牙各3所,哥伦比亚、墨西哥、秘鲁和美国各2所,智利、意大利和巴拉圭各1所。其分享了相关信息和见解:通过护理高等教育机构之间的协作和交流,全球可以加强共同创新和研究合作能力;较少被研究的领域是知识网络生成证据、为当地科学实践提供信息的潜在重点。这些信息将为进一步了解护理发展,以及地方、区域和全球护理证据应用和传播相关的政府政策与计划制订提供参考。

关键词：信息网络创新扩散国际教育交流知识管理护理教育护理教师实践护理院校跨文化护理

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Characterization of the first Wolbachia from the genus Scaptodrosophila,a male-killer from the rainforest species ***

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Insect Science 2022年第5期29卷 1401-1413页

作者： kelly m.Richardson michele Schiffer Perran A.Ross Joshua A.Thia Ary A.Hoffm.nn School of Biosciences Bio21 InstituteThe University of MelbourneVictoriaAustralia Daintree Rainforest Observatory James Cook UniversityCape TribulationQueenslandAustralia

The Scaptodrosophila genus represents a large group of drosophilids with a worldwide distribution and a predom.nance of species in Australia,but there is little information on the presence and impacts of Wolbachia endosymbionts in this *** we describe the first Wolbachia infection from this group,wClay isolated from Scaptodrosophila claytoni(van Klinken),a species from the east coast of *** infection is polymorphic in natural populations,occurring at a frequency of around 6%–10%.wClay causes male killing,producing female-biased lines;most lines showed 100%male killing,though in 1 line it wasnes need to be maintained through the introduction of males unless the infection is removed by tetracycline *** is transmitted at a high fidelity(98.6%)through the maternal lineage and has been stable in 2 laboratory lines across 24 generations,suggesting it is likely to persist in *** infection has not been previously described but is closely related to the male-killing Wolbachia recently described from Drosophila pandora based on multilocus sequence typing and the wsp ***-killing Wolbachia are likely to be comm.n in drosophilids but remain difficult to detect because the infections can often be at a low frequency.

关键词： male-killer multilocus sequence typing phenotypic effects Scaptodrosophila Wolbachia

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Switchgrass Biochar Effects on Plant Biomass and microbial Dynamics in Two Soils from Different Regions

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Pedosphere 2015年第3期25卷 329-342页

作者： Charlene n.kelly Francisco C.CALDERón Verónica ACOSTA-mARTínez maysoon m.mIKHA Joseph BEnJAm.n David W.RUTHERFORD Colleen E.ROSTAD Western Carolina University Department of Geosciences and Natural Resources331 Stillwell HallCullowheeNC 28723 (USA) U.S.Geological Survey Denver CO 80225 (USA) USDA-ARS Akron CO 80720 (USA) USDA-ARS Lubbock TX 79403 (USA)

Biochar am.ndm.nts to soils may alter soil function and fertility in various ways, including through induced changes in the microbial comm.nity. We assessed microbial activity and comm.nity composition of two distinct clayey soil types, an Aridisol from Colorado(CO) in the U.S. Central Great Plains, and an Alfisol from Virginia(VA) in the southeastern USA following the application of switchgrass(Panicum virgatum) biochar. The switchgrass biochar was applied at four levels, 0%, 2.5%, 5%, and 10%, approximately equivalent to biochar additions of 0, 25, 50, and 100 t ha-1, respectively, to the soils grown with wheat(Triticum aestivum) in an eight-week growth chamber experim.nt. We measured wheat shoot biomass and nitrogen(n) content and soil nutrient availability and n m.neralization rates, and characterized the microbial fatty acid methyl ester(FAmE) profiles of the soils. net n m.neralization rates decreased in both soils in proportion to an increase in biochar levels, but the effect was more marked in the VA soil, where net n m.neralization decreased from-2.1 to-38.4 mg kg-1. The 10% biochar addition increased soil p H, electrical conductivity, mehlichand bicarbonate-extractable phosphorus(P), and extractable potassium(K) in both soil types. The wheat shoot biomass decreased from 17.7 to 9.1 g with increm.ntal additions of biochar in the CO soil, but no difference was noted in plants grown in the VA soil. The FAmE recovery assay indicated that the switchgrass biochar addition could introduce artifacts in analysis, so the results needed to be interpreted with caution. non-corrected total FAmE concentrations indicated a decline by 45% and 34% with 10% biochar addition in the CO and VA soils, respectively, though these differences became nonsignificant when the extraction efficiency correction factor was applied. A significant decline in the fungi:bacteria ratio was still evident upon correction in the CO soil with biochar. Switchgrass biochar had the potential to caus

关键词：微生物群落结构植物生物量生物炭柳枝稷地上部生物量弗吉尼亚州土壤功能土壤类型

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Back to school after lockdown: The effect of COVID-19 restrictions on children’s device-based physical activity metrics

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Journal of Sport and Health Science 2022年第4期11卷 530-536页

作者： Liezel Hurter melitta m.narry Gareth Stratton kelly mackintosh Applied Sports TechnologyExercise and Medicine Research Centre(A-STEM)Swansea UniversitySwansea SA18ENUK

Background:The coronavirus disease-2019(COVID-19) pandemic and national lockdowns took away opportunities for children to be physically *** study aimed to determ.ne the effect of the COVID-19 lockdown on accelerometer-assessed physical activity(PA) in children in ***:Eight hundred participants(8-18 years old),stratified by sex,age,and socio-economic status,wore Axivity AX3 accelerometers for7 days in February 2021,during the lockdown,and in may 2021,while in *** accelerometer data were processed in R-package GGIR,and cut-point data,average acceleration(AvAcc),intensity gradient,and the acceleration above which the most active X m.nutes are accumulated(mX) metrics were *** mixed models were used to assess the influence of time-point,sex,age,and socioeconomic status(SES) on ***:During lockdown,moderate-to-vigorous PA was 38.4±24.3 m.n/day;sedentary time was 849.4±196.6 m.n/day;mean± *** levels increased significantly upon return to school(all variables p no sex differences during lockdown(p=0.233),girls engaged in significantly less moderate-to-vigorous PA than boys once back in school(p more,boys had more favorable intensity profiles than girls(intensity gradient:p me-points;upper secondary school girls were the least active group,with an average m30 of 195.2 mg(while in school).Conclusion:The lockdown affected boys more than girls,as reflected by the disappearance of the typical sex difference in PA levels during lockdown,although these were re-established on return to *** secondary school(especially girls) might need specific COVID-recovery intervention.

关键词： Accelerometer Intensity gradient mX metrics

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A comparison of the nutritive value of perennial ryegrass,perennial ryegrass and white clover and multispecies-based farmlet systems

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Grassland Research 2023年第2期2卷 129-139页

作者： Shona Baker mary B.Lynch Fionnuala Godwin Tommy m.Boland Alexander C.O.Evans Paul n.C.murphy Alan K.kelly Helen Sheridan11 UCD School of Agriculture and Food Science University College DublinBelfieldIreland Teagasc Environm.ntal Research Centre Johnstown Castle Co.WexfordIreland UCD Earth Institute University College DublinBelfieldIreland

Background:Limited information is available regarding the nutritive value and structural characteristics of multispecies swards when rotationally ***:Three farmlet types were investigated in terms of their nutritive value:Lolium perenne(LP);***+Trifolium repens(LP+TR);and a multispecies sward containing grasses,legumes and herbs(mSS).Farmlets were stocked with beef steers(2.5 livestock units ha−1),grazed on a 1 ha scale to 6 cm(mSS)and 4 cm(LP and LP+TR)***:A greater ash concentration was found in mSS than LP(84 vs.75 g kg−1 Dm).Both LP+TR and mSS had higher crude protein and lower neutral detergent fibre concentrations than *** relative ranking of water soluble carbohydrate and dry matter(Dm)concentration was LP>LP+TR>*** the leaf component of the LP farmlet contributing more to herbage Dm,the organic matter digestibilities of the swards were ***:The mSS and LP+TR farmlets achieved similar forage quality under intensive grazing to ***,it is worth noting that mSS had a higher concentration of acid detergent lignin,which can negatively impact *** investigation is needed to determ.ne optimal grazing m.nagem.nt practices that can m.nimise the effects of higher lignin concentration on digestibility in multispecies swards.

关键词： forage herbs forage quality grazing cattle legumes multispecies swards nitrogen sustainability

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