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The Association between Perceived Injustice Following Traumatic Injury and Its Impact on Pain-Related, Mental Health and Functional Health Outcomes: A Systematic Review

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Pain Studies and Treatment 2024年第2期12卷 33-47页

作者： Jonathan kelly Dominic Harmon Medical School University of Limerick Limerick Ireland

Background: There is growing evidence suggesting that those who suffer traumatic injury display high levels of perceived injustice which impedes their recovery, both physically and mentally. Aim: The aim of this systematic review was to examine the association between perceived injustice and pain-related, mental health and functional outcomes in patients who have suffered a traumatic injury. Methods: In May 2023, a systematic review of the literature was performed on the electronic databases of PubMed, Google Scholar, Embase, and the Cochrane Database of Systemic Reviews. Papers were collected and analysed as per PRISMA guidelines for systematic reviews. The outcomes of interest were pain intensity, pain interference, disability, depression, anxiety, and quality of life. The initial search identified 59 papers. Of these papers, five studies met the inclusion criteria and were subsequently analysed (N = 1172). Each of the papers was published in peer-reviewed journals in the English language. Individuals with pain or pathology prior to the trauma and those who were not hospitalised following the trauma were excluded from the study. Results: Of the papers reviewed, each study indicated significant associations between perceived injustice and pain, disability, depression, anxiety, post-traumatic stress disorder, as well as reduced return to work status. Conclusion: This systematic review investigated the relationship between perceived injustice and pain-related, mental health, and functional outcomes in trauma patients. The results highlight the negative role that perceived injustice has on recovery following traumatic injury. Further, it provokes the need for future research regarding the implementation of therapeutic interventions and the development of predictive models of injustice.

关键词： Perceived Injustice Trauma Pain Outcomes Mental Health Outcomes Disability

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Acute Colonic Pseudo-Obstruction (ACPO): An Expanding Colon with Unusual Risk Factors

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Open Journal of Internal Medicine 2024年第2期14卷 167-174页

作者： kelly Schulte Alyson Terry Grace Boyle Dmitriy Scherbak HCA Healthone Sky Ridge Medical Center Lone Tree Colorado USA

The distention of the colon without mechanical or anatomical obstruction, Acute Colonic Pseudo-obstruction (ACPO), is a common condition occurring in the critically ill. ACPO in the setting of an acute pulmonary embolism and embolic stroke is a rarity. A 76-year-old female with shortness of breath, left hemiparesis and right-sided paresthesias presented with acute pulmonary embolism and acute infarcts of the left caudate nucleus, thalamus and occipital lobe. Her hospitalization was complicated with persistent distention of the large bowel without dilation of the small bowel. Empiric antibiotics were initiated without improvement and laboratory studies including Clostridium difficile were negative. She underwent nasogastric decompression and two decompressive colonoscopies with a resolution of her symptoms. This case illustrates an example of acute abdominal distension, without underlying etiology, in the setting of acute embolism of the pulmonary and cerebral vasculature. Early identification and action with decompressive colonoscopy were key to preventing further bowel damage or rupture.

关键词： Acute Colonic Pseudo-Obstruction ACPO Ogilvie’s Syndrome Colonic Dilation Acute Embolic Infarcts Cerebrovascular Accident Pulmonary Embolism PE

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Predicting Malaria Dynamics in Burundi Using Deep Learning Models

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Journal of Applied Mathematics and Physics 2024年第8期12卷 2904-2917页

作者： Daxelle Sakubu kelly Joelle Gatore Sinigirira David Niyukuri Doctoral School University of Burundi Bujumbura Burundi Department of Mathematics University of Burundi Bujumbura Burundi The South African Department of Science and Technology-National Research Foundation (DST-NRF) Centre of Excellence in Epidemiological Modelling and Analysis (SACEMA) Stellenbosch University Cape Town South Africa

Malaria continues to be a major public health problem on the African continent, particularly in Sub-Saharan Africa despite the ongoing efforts and significant progress that has been made. In the case of Burundi, malaria remains a major public health concern in the general population. In the literature, there are limited malaria prediction models for Burundi knowing that such tools are much needed for intervention design. In this study, deep-learning models are built to estimate malaria cases in Burundi. The forecast of malaria cases was carried out both at the provincial and national levels. Long short term memory (LSTM) model, a type of deep learning model, has been used to achieve best results using climate-change related factors such as temperature, rainfall, relative humidity, together with malaria historical data and human population. With this model, the results showed that different parameter tuning can be used to determine the minimum and maximum expected malaria cases. The univariate version of that model (LSTM), which learns from previous dynamics of malaria cases, gives more precise estimates, but both univariate and multivariate models have the same overall trends at the province level and country level.

关键词： Malaria Prediction Deep Learning Long-Short-Term Memory (LSTM) Burundi

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A rat model of multicompartmental traumatic injury and hemorrhagic shock induces bone marrow dysfunction and profound anemia

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Animal Models and Experimental Medicine 2024年第3期7卷 367-376页

作者： Lauren S.kelly Jennifer A.Munley Erick E.Pons Kolenkode B.Kannan Elizabeth M.Whitley Letitia E.Bible Philip A.Efron Alicia M.Mohr Department of Surgery and Sepsis and Critical Illness Research Center University of Florida College of MedicineGainesvilleFloridaUSA Pathogenesis LLCGainesvilleFloridaUSA

Background:Severe trauma is associated with systemic inflammation and organ *** rodent trauma models are the mainstay of postinjury research but have been criticized for not fully replicating severe human *** aim of this study was to create a rat model of multicompartmental injury which recreates profound traumatic ***:Male Sprague-Dawley rats were subjected to unilateral lung contusion and hemorrhagic shock(LCHS),multicompartmental polytrauma(PT)(unilateral lung contusion,hemorrhagic shock,cecectomy,bifemoral pseudofracture),or na?ve ***,plasma toll-l ike receptor 4(TLR4),hemoglobin,spleen to body weight ratio,bone marrow(BM)erythroid progenitor(CFU-GEMM,BFU-E,and CFU-E)growth,plasma granulocyte colony-stimulating factor(G-CSF)and right lung histologic injury were assessed on day 7,with significance defined as p values<0.05(*).Results:Polytrauma resulted in markedly more profound inhibition of weight gain compared to LCHS(p=0.0002)along with elevated plasma TLR4(p<0.0001),lower hemoglobin(p<0.0001),and enlarged spleen to body weight ratios(p=0.004).Both LCHS and PT demonstrated suppression of CFU-E and BFU-E growth compared to naive(p<0.03,p<0.01).Plasma G-CSF was elevated in PT compared to both na?ve and LCHS(p<0.0001,p=0.02).LCHS and PT demonstrated significant histologic right lung injury with poor alveolar wall integrity and interstitial ***:Multicompartmental injury as described here establishes a reproducible model of multicompartmental injury with worsened anemia,splenic tissue enlargement,weight loss,and increased inflammatory activity compared to a less severe *** may serve as a more effective model to recreate profound traumatic injury to replicate the human inflammatory response postinjury.

关键词： anemia i nflammation polytrauma pseudofracture shock

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Psychiatric Sequelae of Chronic Pruritic Dermatoses

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Open Journal of Medical Psychology 2024年第2期13卷 25-38页

作者： kelly Frasier Vivian Li Kathleen Click Christina Dudzik Michelle Sobotka Evadne Rodriguez Karina Stech Nuvance Health/Vassar Brothers Medical Center Poughkeepsie NY USA School of Osteopathic Medicine Kansas City University Kansas City MO USA Touro College of Osteopathic Medicine Middleton Campus Middletown NY USA Abrazo Health Network Goodyear AZ USA School of Medicine University of Missouri-Columbia Columbia MO USA Lewis Katz School of Medicine at Temple University Philadelphia PA USA

This comprehensive review investigates the significant psychological impact and profound psychological comorbidities found in individuals suffering from chronic pruritic dermatoses, including atopic dermatitis, chronic urticaria, and prurigo nodularis. Highlighting the complex, reciprocal relationship between pruritus and psychiatric conditions such as depression, anxiety, and sleep disturbances, this paper elucidates the comprehensive impact of dermatological disorders on the skin in addition to the far-reaching effects on an individual’s psychological well-being. By evaluating the efficacy of integrated psychodermatological interventions, including cognitive behavioral therapy, mindfulness practices, pharmacological treatments, and innovative telepsychiatry and digital health solutions, this review aims to lay the foundation for a more holistic approach to treatment of concurrent dermatological and psychiatric conditions. Future research endeavors should delve deeper into the mechanistic foundation of the pruritus-psychiatry interface, the refinement of tailored treatment strategies, and the evaluation of long-term patient outcomes. In doing so, this review seeks to contribute to the optimization of patient care and well-being, underscoring the pivotal role of addressing both dermatological and psychological needs in achieving comprehensive health outcomes.

关键词： Psychodermatology Chronic Pruritic Dermatoses Psychological Comorbidities Integrated Interventions Pruritus-Psychiatry Interface

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The Impact of Psychosocial Influences on Chronic Wound Healing

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Open Journal of Medical Psychology 2024年第3期13卷 39-57页

作者： kelly Frasier Vivian Li Sara Christoforides Kathleen Daly Alexandra Loperfito Karina Stech Milena Dragovic Nuvance Health/Vassar Brothers Medical Center Poughkeepsie NY USA Lake Erie College of Osteopathic Medicine New York NY USA Medical College of Georgia Augusta University Augusta GA USA Edward Via College of Osteopathic Medicine Blacksburg VA USA Lewis Katz School of Medicine Temple University Philadelphia PA USA College of Osteopathic Medicine California Health Sciences University Clovis CA USA

This comprehensive review explores the intricate dynamics between psychosocial factors and chronic wound healing processes, specifically focusing on prevalent conditions such as pressure ulcers, diabetic foot ulcers, and venous leg ulcers. By examining the roles of psychiatric conditions, including depression, anxiety, and post-traumatic stress disorder (PTSD), this paper illuminates how these factors intricately influence wound healing dynamics, including mechanisms of pain perception and inflammatory responses. Furthermore, we evaluate the effectiveness of integrated biopsychosocial interventions, which encompass a holistic approach to wound care, thereby enhancing healing outcomes for dermatology patients. Future studies should focus on investigating the specific psychosocial determinants that significantly influence wound healing, exploring novel therapeutic strategies, and implementing personalized interventions to meet the unique needs of each patient. Such endeavors hold promise in advancing the fields of psychodermatology and wound management, fostering a deeper understanding and application of psychosocial considerations in dermatological care.

关键词： Psychosocial Factors Chronic Wound Healing Biopsychosocial Interventions Psychiatric Conditions Dermatology Patients

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非洲Okavango裂谷及邻区三维剪切波速度与径向各向异性结构研究

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地球物理学报 2024年第10期67卷 3796-3813页

作者：王拓王旭陈凌喻志超胡少乾 Stephen S.Gao kelly H.Liu 中国科学院地质与地球物理研究所岩石圈演化与环境演变全国重点实验室北京100029 中国科学院大学地球与行星科学学院北京100049 中国地质大学地球物理与空间信息学院地球内部多尺度成像湖北省重点实验室武汉430074 Department of Earth Sciences and Engineering Missouri University of Science and TechnologyRollaMO 65409USA

非洲Okavango裂谷是东非裂谷系最年轻且仍处于发育初期阶段的裂谷,研究其地下结构及变形特征有助于深入了解东非裂谷系裂解初期结构构造特征,并进一步完善对裂谷系裂解动力学机制的认识.本文收集Okavango裂谷区域内41个宽频地震台站的... 详细信息

非洲Okavango裂谷是东非裂谷系最年轻且仍处于发育初期阶段的裂谷,研究其地下结构及变形特征有助于深入了解东非裂谷系裂解初期结构构造特征,并进一步完善对裂谷系裂解动力学机制的认识.本文收集Okavango裂谷区域内41个宽频地震台站的连续波形数据,采用背景噪声技术获取Rayleigh和Love波相速度频散数据,进一步通过直接成像技术获得研究区地下50 km深度范围内的三维剪切波速度和径向各向异性结构.剪切波速度和径向各向异性结果显示,Okavango裂谷的中地壳具有低速和负径向各向异性(V_(SH)V_(SV))的特征,结合前人资料,本文认为Okavango裂谷的发育可能是在先存构造薄弱带上由板内相对运动所提供的水平方向构造应力诱发的.此外,我们的结果还显示,在邻区Zimbabwe克拉通西南部,中、下地壳呈现出负径向各向异性,这一观测支持Okavango岩墙群侵入地壳导致该区域地壳增厚的认识.

关键词： Okavango裂谷裂谷发育机制背景噪声剪切波速度径向各向异性

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有说服力的讲故事艺术（英文）

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英语画刊(高中版) 2024年第24期 3-5页

作者： kelly D.Parker

沟通专家凯利·D·帕克说：“讲故事是最强大的营销和领导工具之一。”在这个演讲中，她解释了故事如何让各种提案更令人难忘，并展示了如何讲述一个引人注目的故事，以连接、说服和推动有意义的行动。

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Polycystic Ovarian Syndrome (PCOS): Exploring Its Impact on Obstetrical Outcomes

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Open Journal of Obstetrics and Gynecology 2024年第8期14卷 1111-1123页

作者： Ranjitha Vasa Gayatri Venkataraman kelly Gorman Rythika Francis Elise Zwicklbauer Julia Fisher Polina Safovich Mudar Dalloul Ozgul Muneyyirci-Delale Department of Obstetrics and Gynecology SUNY Downstate Health Science University Brooklyn United States of America Department of Obstetrics and Gynecology Kings County Hospital Center NYC Health and Hospitals Brooklyn United States of America

Polycystic ovarian syndrome (PCOS) disrupts ovulation leading to both infertility and miscarriage;yet, its impact on obstetrical outcomes remains largely uncertain due to conflicting findings. We analyzed data from the CDC Pregnancy Risk Assessment of Monitoring System, specifically Standard Core and Phase 8 responses, with 9549 respondents across the United States through SPSS 28 software in this cross-sectional study. Two variables assessed PCOS status in respondents: history of PCOS and PCOS during pregnancy. With a history of PCOS, there were significantly increased odds of diabetic (OR 1.665, p < 0.001), hypertensive disorders (OR 1.589, p < 0.001) during pregnancy, neonatal mortality (OR 1.550, p < 0.001), cesarean section (C/S) (OR 1.489, p < 0.001), and preterm prelabor rupture of membranes (PPROM) (OR 2.081, p < 0.001). With PCOS diagnosed during pregnancy, there were significantly greater odds of diabetes (OR 3.278, p < 0.001), hypertensive disorders (OR 2.935, p < 0.001) during pregnancy, and significantly decreased risk for small for gestational age (2 standard deviations) (OR 0.337, p = 0.024). PCOS is a significant risk factor that contributes to maternal morbidity. Our results support the hypothesis that PCOS’ impact extends well into a woman’s obstetrical journey, with varying degrees of associated adverse maternal and fetal risks. Preliminary pathophysiologic explanations associated with PCOS gestational diabetes include pre-existing insulin resistance. Meanwhile, altered placentation and endovascular changes associated with PCOS secondary to a baseline deranged metabolic environment predispose patients to developing hypertensive disorders, PPROM, and preterm delivery. Associations between neonatal mortality and C/S can be attributed to elevated maternal body mass index. The pathophysiologic link between PCOS and the above obstetrical outcomes still remains unknown, necessitating further investigation;however, this study identifies the outcomes that

关键词： PCOS Polycystic Ovarian Syndrome Obstetrics Reproduction Pregnancy

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管理控制系统对员工学习影响的会计研究综述(二)

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中国管理会计 2024年第4期 113-120页

作者： Khim kelly Garrison Nuttall 王玮坤(翻译) 宿文迪(翻译) 中佛罗里达大学中欧国际工商学院

本文是关于管理控制系统对员工学习影响的会计研究综述之第二部分,重点确定未来相关研究的高潜领域。第一部分(上期发表的《管理控制系统对员工学习影响的会计研究综述(一)》)回顾了关于不同类型的管理控制系统(正式控制与非正式控制)... 详细信息

本文是关于管理控制系统对员工学习影响的会计研究综述之第二部分,重点确定未来相关研究的高潜领域。第一部分(上期发表的《管理控制系统对员工学习影响的会计研究综述(一)》)回顾了关于不同类型的管理控制系统(正式控制与非正式控制)与不同类型的员工学习(经验学习与替代学习)之间关系的研究成果。本篇将以第一部分的文献综述为背景,重点讨论管理会计研究将如何加深我们对管理控制系统影响员工学习的理解。

关键词：管理控制系统经验学习替代学习

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