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World Journal of Gastroenterology 2005年第12期11卷 1779-1784页

作者： Yi-yin Jan Chun-Nan Yeh Ta-Sen Yeh Tse-ching Chen Department of Surgery Department of Pathology

AIM: To analyze the prognostic factors influencing the overall survival of peripheral cholangiocarcinoma (PCC)patients undergoing surgical treatment during 25 years at a single ***: This study retrospectively reviewed prospectively collecting data about 373 patients with histologically proven PCC who underwent surgical treatment between 1977 and ***: Three hundred and seventy-three PCC patients (159 men and 214 women) underwent surgical treatment from 1977 to 2001. Among them, 187 PCC patients underwent hepatectomy and 135 had curative resection (curative resectability rate: 36.2%). The follow-up duration ranged from 1.05 to 167.6 mo (mean/median = 14.1/7.2 mo).Overall cumulative survival rates at 1, 3, and 5 years were 32.5%, 9.2%, and 4.1%, respectively. Univariate log-rank analysis identified the following as adverse influences on overall survival: presence of symptoms, absence of mucobilia, elevated CEA and CA 19-9 levels, non-papillary tumor type, receiving non-hepatectomy, advanced tumor staging, lack of post-operative chemotherapy, and radiotherapy. Meanwhile, multivariate Cox's proportional hazard analysis demonstrated that absence of mucobilia,non-papillary tumor type, advanced tumor staging, nonhepatectomy, and lack of post-operative chemotherapy were the five independent prognostic factors that adversely affected overall ***: Favorable overall survival of PCC patients undergoing surgical treatment depends on early tumor stage, presence of mucobilia, papillary tumor type, hepatic resection, and post-operative chemotherapy.

关键词：手术治疗肝切除手术化学治疗外周性胆管癌

Synchronous colorectal cancer: Clinical, pathological and molecular implications

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World Journal of Gastroenterology 2014年第22期20卷 6815-6820页

作者： Alfred King-yin lam Sally Sze-Yan Chan Melissa Leung Cancer Molecular Pathology Griffith Health InstituteGriffith UniversityGold Coast QLD 4222QueenslandAustralia

Synchronous colorectal carcinoma refers to more than one primary colorectal carcinoma detected in a single patient at initial presentation.A literature review has shown that the prevalence of the disease is approximately 3.5%of all colorectal *** disease has a male to female ratio of 1.8:*** mean age at presentation of patients with synchronous colorectal cancer is in the early half of the seventh *** with inflammatory bowel diseases(ulcerative colitis and Crohn’s disease),hereditary non-polyposis colorectal cancer,familial adenomatous polyposis and serrated polyps/hyperplastic polyposis are known to have a higher risk of synchronous colorectal *** predisposing factors account for slightly more than 10%of synchronous colorectal *** colorectal carcinoma is more common in the right colon when compared to solitary colorectal *** pathological examination,some synchronous colorectal carcinomas are mucinous *** are usually associated with adenomas and metachronous colorectal *** of the patients with synchronous colorectal cancer have two carcinomas but up to six have been reported in one *** with synchronous colorectal carcinoma havea higher proportion of microsatellite instability cancer than patients with a solitary colorectal ***,limited data have revealed that in many synchronous colorectal carcinomas,carcinomas in the same patient have different patterns of microsatellite instability status,p53 mutation and K-ras ***,the prognosis of patients with synchronous colorectal carcinoma is not significantly different from that in patients with solitary colorectal carcinoma,although a marginally better prognosis has been reported in patients with synchronous colorectal carcinoma in some series.A different management approach and long-term clinical follow-up are recommended for some patients with synchronous colorectal cancer.

关键词： Synchronous carcinoma Colorectal carci-noma Preval

玻璃体腔注射Bevacizumab联合Ahmed青光眼阀植入治疗新生血管性青光眼

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中国实用眼科杂志 2011年第8期29卷 779-784页

作者：张海涛王保君胡俊喜徐英英 Wai-ching lam 新乡医学院第一附属医院眼科河南省新乡市453100 加拿大多伦多大学西部医院眼科

目的观察玻璃体腔注射Bevacizumab联合Ahmed青光眼阀植入治疗新生血管性青光眼（NVG）的术后疗效和并发症。方法回顾性临床病例对照研究。选择新乡医学院第一附属医院眼科在2007年至2008年2月间接受过玻璃体腔注射Bevacizumab0．05mL／1... 详细信息

目的观察玻璃体腔注射Bevacizumab联合Ahmed青光眼阀植入治疗新生血管性青光眼（NVG）的术后疗效和并发症。方法回顾性临床病例对照研究。选择新乡医学院第一附属医院眼科在2007年至2008年2月间接受过玻璃体腔注射Bevacizumab0．05mL／1．25mg和Ahmed青光眼阀植入术的NVG患者，术前及术后定期随访检查，记录抗青光眼药物数量、Snellen视力、Godmann压平式眼压计测量的IOP等项目。手术成功标准：术后IOP处于6～21mmHg范围内，不再使用或不需额外增加抗青光眼药物治疗，不需进一步抗青光眼手术治疗，术眼视力未丧失光感。结果纳入分析35例（35只眼），随访时间（24．6±14.2）月。Ahmed青光眼阀植入术后IOP比术前降低（P〈0．01），其中术前、术后6月、1年和3年分别为（44．9±4．8）mmHg、（1822±4．0）mmHg、（15．5±3．3）mmHg和（9．8±2．6）mmHg（1mmHg=0．133kPa）；抗青光眼药物数量术后较术前减少（P〈0．01），其中术前、术后6月、1年和3年分别为（3．3±0．5）种、（0．9±0．5）种、（0．8±0．9）种和（0．8±0．6）种。最后一次随访时，视力较术前保持稳定19例（54．3％），改善4例（11．4％），下降12例（34．3％），丧失光感3例（8．6％）。经3年随访，失败病例7例（20．0％o经Kaplan—Meier生存分析，术后1年、2年、3年累计生存率分别为82．9％、74．1％和71．0％。经Cox逐步回归分析，术前视力较差（〈20／400）与术后生存时间具有相关性（RR=3．571，P〈0．05）。术后并发症8例（22．9％），其中前房出血2例（5．7％），脉络膜渗液2例（5．7％），其余并发症较少见，未发生需要取出引流阀的并发症。结论玻璃体腔注射Bevacizumab联合Ahmed青光眼阀植入术安全有效，可作为新生血管性青光眼临床治疗方法之一。

关键词： Ahmed青光眼阀新生血管性青光眼 Bevacizumab 玻璃体注射

Primary squamous cell carcinoma of the liver:A successful surgically treated case

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World Journal of Gastroenterology 2006年第33期12卷 5419-5421页

作者： Hsiang-Lin Lee Yu-yin Liu Chun-Nan Yeh Kun-Chun Chiang Tse-ching Chen Yi-yin Jan Department of Surgery Chang Gung Memorial Hospital Chang Gung University Taiwan China Department of Pathology Chang Gung Memorial Hospital Chang Gung University Taiwan China

Primary squamous cell carcinoma (SCC) of the liveris rare. Totally nine such cases have been reportedin the literature. Primary SCC of the liver has beenreported to be associated with hepatic teratoma,hepatic cyst, or hepatolithiasis. Complete remission ofpoorly differentiated SCC of the liver could be achievedby systemic chemotherapy followed by surgery orremarkably respond to hepatic arterial injection of lowdose chemotherapeutic drugs. Here we report the fi rstcase of primary SCC of the liver presenting as a solidtumor and receiving successful hepatic resection with9-mo disease free survival.

关键词：原发性鳞状细胞癌肝癌手术治疗临床

基于IMB模型的风险预警护理对良性前列腺增生患者康复的影响

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青岛医药卫生 2024年第1期56卷 1-5页

作者：常秀梅陈海燕丁洁琼潘晓芳殷亚江苏医药职业学院附属东台医院江苏东台224200 东台市人民医院江苏东台224200

目的探讨基于信息-动机-行为技巧(IMB)模型的风险预警护理对良性前列腺增生患者康复的影响。方法选取我院2022年08月到2023年08月收治的82例良性前列腺增生患者,应用随机数字表法将其分为观察组与对照组,各组均为41例。所有患者均采... 详细信息

目的探讨基于信息-动机-行为技巧(IMB)模型的风险预警护理对良性前列腺增生患者康复的影响。方法选取我院2022年08月到2023年08月收治的82例良性前列腺增生患者,应用随机数字表法将其分为观察组与对照组,各组均为41例。所有患者均采取经尿道等离子电切术治疗,对照组采取围术期常规护理,观察组在对照组基础上增加IMB模型的风险预警护理,分别在护理前后应用自我护理能力量表(ESCA)对患者自我护理能力进行评价,对比两组首次下床时间、尿管拔除时间、首次进食时间和住院时间,最后对比两组并发症发生情况。结果护理后两组的健康知识水平、自我护理技能、自护责任感、自我概念相关ESCA评分均升高,且观察组高于对照组(P<0.05);观察组患者首次下床时间、尿管拔除时间、首次进食时间和住院时间明显低于对照组(P<0.05);观察组术后并发症发生率明显低于对照组(P<0.05)。结论基于IMB模型的风险预警护理对良性前列腺增生患者围术期护理效果显著,可提升患者自我护理能力,促进其早日康复,辅助降低术后并发症发生率。

关键词：信息-动机-行为技巧模型风险预警良性前列腺增生康复水平自护能力

Advanced Metering Infrastructure for Electric Vehicle Charging

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Smart Grid and Renewable Energy 2011年第4期2卷 312-323页

作者： Lun Ka lam King Tim Ko Hoi Yan Tung Hoi ching Tung Wah ching Lee Kim Fung Tsang Loi Lei Lai 不详

The widely adoption of Electric Vehicle (EV) has been identified as a major challenge for future development of smart grids. The ever increasing electric vehicle charging further increases the energy demand. This paper reports the development of an Advanced Metering Infrastructure (AMI) as an effective tool to reshape the load profile of EV charging by adopting appropriate demand side management strategy. This paper presents a total solution for EV charging service platform (EVAMI) based on power line and internet communication. It must be stressed that the development of Third Party Customer Service Platform in this investigation facilitates a single bill to be issued to EV owners. Hence, EV owners understand their energy usage and thus may perform energy saving activity efficiently. Experiment and evaluation of the proposed system show that the throughput achieved is about 5 Mbps at 10 ms end to end delay in Power line Communication. By introducing two dimensional dynamic pricing and charging schedule, the proposed EVAMI successfully reduces 36% peak consumption and increases the “off peak” consumption by 54%. Therefore the EVAMI does not only reduce the peak consumption but also relocates the energy demand effectively.

关键词： Electric Vehicle Charging Advanced Metering Infrastructure Power Line Communication Demand Response

Predicting eczema severity beyond childhood

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世界儿科杂志:英文版 2016年第1期12卷 44-48页

作者： Kam Lun Hon yin-ching K.Tsang Terence Chuen W.Poon Nga Hin Pong Matthew Kwan Shirley Lau Yuen-Chun Chiu Hin-Hei Wong Ting-Fan Leung Department of Pediatrics The Chinese University of Hong KongPrince of Wales HospitalHong KongChina Faculty of Medicine The Chinese University of Hong KongChina

Background:We evaluated factors associated with eczema severity in ***:Nottingham Eczema Severity Score(NESS),family and personal history of atopy,skin prick test for common food and aeroallergens,highest serum IgE level and eosinophil count were *** with paired NESSs(childhood-NESS is NESS performed at10 years)were further ***:Adolescence-NESS(n=383 patients)was associated with eczema onset in infancy,dust mite and food allergen sensitization,dietary avoidance,use of wet wrap,traditional Chinese medicine,immunomodulant(azathioprine or cyclosporine),high IgE level,eosinophil count,but not with family/personal history of ***-two patients had both childhood-NESS and adolescence-NESS(mean follow-up of 6.8 years)showing that adolescence-NESS was associated with childhood-NESS severity grades(P=0.034).Of these patients,48%remained in the same severity grades,whereas 39%improved,and 13%deteriorated from childhood to ***:It is not possible to assure parents that their child can outgrow *** eczema prognosis research,long-term follow-up is warranted.

关键词： atopic dermatitis atopy eczema Nottingham Eczema Severity Score prognosis

Prevalence and risk factors of intestinal parasitism among two indigenous subethnic groups in Peninsular Malaysia

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Infectious Diseases of Poverty 2016年第1期5卷 700-714页

作者： Yuee Teng Chin Yvonne Ai Lian Lim Chun Wie Chong Cindy Shuan Ju Teh Ivan Kok Seng Yap Soo ching Lee Mian Zi Tee Vinnie Wei yin Siow Kek Heng Chua Department of Biomedical Science Faculty of MedicineUniversity of Malaya50603 Kuala LumpurMalaysia Department of Parasitology Faculty of MedicineUniversity of Malaya50603 Kuala LumpurMalaysia Department of Life Sciences School of PharmacyInternational Medical University57000 Kuala LumpurMalaysia Department of Medical Microbiology Faculty of MedicineUniversity of Malaya50603 Kuala LumpurMalaysia

Background:Intestinal parasitic infections(IPIs)among indigenous people have been widely documented in Malaysia,however,the prevalence of these infections remains *** the past,most studies have focused on specific species of parasites but polyparasitism has received limited *** addition,epidemiology studies on indigenous people tend to consider them as a homogenous group,whereas in reality different sub-ethnic groups have different cultural and living *** in living habits such as personal hygiene practices may predispose different groups to different parasitic *** better understand prevalence and risk factors of intestinal parasitism among different sub-ethnic groups,the present study was conducted among two sub-ethnic groups of indigenous people(Temuan and Mah Meri)residing in Selangor state,***:A cross-sectional study that focused on two distinct sub-ethnic groups was carried out from February to September *** samples were collected from 186 participants and examined using the formalin-ether sedimentation technique.A molecular approach was adopted to conduct a genetic characterisation of the ***,questionnaires were administered to obtain information on the demographics,socioeconomic backgrounds and behavioural risks relating to the participants,as well as information about their *** analyses(*** and multivariate logistic regression analyses)were performed to measure risk ***:For Temuan communities,trichuriasis(64.2%)was the most common infection found,preceding hookworm infection(34%),ascariasis(7.5%),giardiasis(14.2%)and amoebiasis(7.5%).As for the Mah Meri communities,trichuriasis(77.5%)prevailed over ascariasis(21.3%),hookworm(15%),giardiasis(7.5%)and amoebiasis(3.8%).Significant differences in proportions of trichuriasis,ascariasis and hookworm infections were observed between the Temuan and Mah Meri sub-ethnic *** was more

关键词： Intestinal parasites Intestinal parasitism Indigenous people Risk factors Prevalence Sub-ethnic group Temuan sub-ethnic group Mah Meri sub-ethnic group Peninsular Malaysia

世界卫生组织《感染预防与控制专业人员核心能力》实践路径

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华西医学 2023年第3期38卷 326-330页

作者：程棣妍乔甫世界卫生组织传染病流行病学及感染控制合作中心香港大学公共卫生学院中国香港999077 四川大学华西医院医院感染管理部成都610041

2020年,世界卫生组织发布了《感染预防与控制专业人员核心能力》,该文件有助于感染预防与控制专业人员通过相关的培训、实践和评估,使感染预防与控制的能力标准化,是一个实用性指南。将核心能力引入感染预防与控制,是感染预防与控制作... 详细信息

2020年,世界卫生组织发布了《感染预防与控制专业人员核心能力》,该文件有助于感染预防与控制专业人员通过相关的培训、实践和评估,使感染预防与控制的能力标准化,是一个实用性指南。将核心能力引入感染预防与控制,是感染预防与控制作为专业被医学其他专业认可的至关重要的一环。《感染预防与控制专业人员核心能力》也是该领域从业人员从新手成长为专家的职业发展指南。该文详细阐述了该文件中与感染预防与控制专业人员角色和职责有关的内容,以期为我国的从业人员提供职业参考。

关键词：核心能力感染预防与控制实践路径

Traditional Chinese Medicine diagnoses in persons with ketamine abuse

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Journal of Traditional Chinese Medicine 2013年第2期33卷 164-169页

作者： WaikwongTang Ming lam Wingnang Leung Waizhu Sun Tszting Chan Gabor S Ungvari Department of Psychiatry Chinese University of Hong Kong Castle Peak Hospital School of Chinese Medicine Chinese University of Hong Kong Department of Surgery Chinese University of Hong KongHong Kong SARChina School of Psychiatry and Clinical Neurosciences University ofWestern AustraliaPerthAustralia

OBJECTIVES:To explore the distribution of TCM patterns in ketamine users and the inter-rater reliability ofTCM diagnosis amongTCM ***:Eighty-four subjects recruited from substance abuse clinics and non-governmental counseling services catering for ketamine abusers were examined by one or two TCM *** distribution and inter-rater reliability of the TCM diagnoses between the two TCM practitioners were described and ***:Seven TCM patterns were *** four most common patterns were the Heart yin deficiency(29.8%),Kidney Yang deficiency(26.2%),Kidneyyin deficiency(19.0%),and SpleenYang defi-ciency(14.3%).The agreement between the two TCM practitioners was 59%;the kappa for the three most common patterns was 0.472(P=0.003).The proportion of men was lower in the Kidneyyin deficiency group(18.8%),in comparison to the Heart yin deficiency(60.0%,P=0.009) and KidneyYang deficiency group(59.1%,P=0.013).CONCLUSION:The differences between the TCM groups in terms of the source of referral and number of drug uses other than ketamine were of borderline *** research should focus on validating diagnostic tools and improving inter-rater reliability in TCM to enhance the quality of clinical trials ofTCM treatments for ketamine abuse.

关键词：诊断能力氯胺酮中国传统医学中医诊断肾阳虚临床试验中医治疗诊断工具