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LPS诱导的巨噬细胞来源外泌体促进巨噬细胞抗结核分枝杆菌自噬

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蚌埠医学院学报 2024年第4期49卷 438-442,447页

作者：方芳杨珂佳王瑞祥钱中清蚌埠医科大学检验医学院安徽蚌埠233030 蚌埠医科大学慢性疾病免疫学基础与临床安徽省重点实验室安徽蚌埠233030

目的:探讨LPS诱导的巨噬细胞来源外泌体对巨噬细胞抗结核分枝杆菌(***)自噬的作用及机制研究。方法:使用THP-1细胞诱导建立H37Ra感染巨噬细胞模型,抽提并鉴定巨噬细胞外泌体;抽提LPS诱导的巨噬细胞外泌体与H37Ra感染巨噬细胞共培养,使用... 详细信息

目的:探讨LPS诱导的巨噬细胞来源外泌体对巨噬细胞抗结核分枝杆菌(***)自噬的作用及机制研究。方法:使用THP-1细胞诱导建立H37Ra感染巨噬细胞模型,抽提并鉴定巨噬细胞外泌体;抽提LPS诱导的巨噬细胞外泌体与H37Ra感染巨噬细胞共培养,使用Dil荧光标记外泌体,荧光显微镜观察外泌体吸收情况,采用荧光定量PCR、流式细胞术、Western blotting等方法,明确外泌体对巨噬细胞抗***自噬的影响。结果:成功抽提并鉴定LPS刺激的巨噬细胞外泌体,吸收普通外泌体的巨噬细胞自噬水平无明显变化,吸收LPS诱导的外泌体后的巨噬细胞其自噬水平显著提高,共培养时加入外泌体抑制剂后促进巨噬细胞自噬作用消失;H37Ra感染的巨噬细胞吸收LPS诱导的外泌体后,其自噬水平增强,显著提高对***的杀伤能力及人白细胞介素12的分泌。结论:LPS诱导的巨噬细胞来源外泌体可促进巨噬细胞抗***自噬。

关键词：巨噬细胞外泌体结核分枝杆菌自噬

Privacy-Preserving Decision Protocols Based on Quantum Oblivious Key Distribution

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Computers, Materials & Continua 2020年第9期64卷 1915-1928页

作者： kejia Zhang Chunguang Ma Zhiwei Sun Xue Zhang Baomin Zhou Yukun Wang School of Computer Science and Technology Harbin Engineering UniversityHarbin150001China School of Mathematical Science Heilongjiang UniversityHarbin150080China State Key Laboratory of Networking and Switching Technology Beijing University of Posts and TelecommunicationsBeijing100876China Center for Quantum Computing Peng Cheng LaboratoryShenzhen518055China College of Computer Science and Engineering Shandong University of Science and TechnologyQingdao266590China School of Artificial Intelligence Shenzhen PolytechnicShenzhen518055China Department of Electrical and Computer Engineering National University of Singapore117583Singapore

Oblivious key transfer(OKT)is a fundamental problem in the field of secure multi-party *** makes the provider send a secret key sequence to the user obliviously,i.e.,the user may only get almost one bit key in the sequence which is unknown to the ***,a number of works have sought to establish the corresponding quantum oblivious key transfer model and rename it as quantum oblivious key distribution(QOKD)from the well-known expression of quantum key distribution(QKD).In this paper,a new QOKD model is firstly proposed for the provider and user with limited quantum capabilities,where both of them just perform computational basis measurement for single *** we show that the privacy for both of them can be protected,since the probability of getting other’s raw-key bits without being detected is exponentially ***,we give the solutions to some special decision problems such as set-member decision and point-inclusion by announcing the improved shifting strategies followed ***,the further discussions and applications of our ideas have been presented.

关键词： Quantum cryptography quantum computing privacy-preserving quantum oblivious key distribution set-member decision point-inclusion decision

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2023年美国绿色化学挑战奖评述

广东化工 2024年第17期51卷 81-82,95页

作者：韩佳豪许昊天闫柯佳王开亚南京航空航天大学江苏南京211106

面对着日益严重的环境问题和能源危机,人们提高了对绿色化学的重视程度。美国绿色化学挑战奖就是一个表彰在绿色化学领域做出卓越贡献的人才的奖项。今年的美国绿色化学挑战奖已于10月23日在美国环保署网站上公布,学术奖授予了密歇根大... 详细信息

面对着日益严重的环境问题和能源危机,人们提高了对绿色化学的重视程度。美国绿色化学挑战奖就是一个表彰在绿色化学领域做出卓越贡献的人才的奖项。今年的美国绿色化学挑战奖已于10月23日在美国环保署网站上公布,学术奖授予了密歇根大学的理查德·莱恩(RichardLaine)教授;小企业奖授予了ModernMeadow公司;变更合成路线奖授予了研究公司Solugen及其工厂BiafoxgeTM;变更溶剂/反应条件奖授予了公司Captis Aire;设计更安全化学品奖授予了高乐氏公司The Clorox Company;气候变化奖则授予了AirCompany。这些获奖者或获奖公司都在绿色化学领域做出了卓越的贡献。本篇文章将对2023年度美国绿色化学挑战奖的获奖者/获奖公司进行介绍。

关键词：美国绿色化学挑战奖绿色能源化学方法

基于FCM-LSTM的软件运行资源变化规律方法研究

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微型电脑应用 2024年第3期40卷 1-6页

作者：李春生王胡景张可佳富宇东北石油大学计算机与信息技术学院黑龙江大庆163319

软件在运行过程中会消耗资源,此过程存在两个问题,一是难以确定资源消耗发生变化的拐点,二是同一软件同一模块运行不同任务时,所产生的数据样本数量级差异过大。基于此,提出一种结合FCM和LSTM的算法研究软件运行资源变化规律的方法,利用... 详细信息

软件在运行过程中会消耗资源,此过程存在两个问题,一是难以确定资源消耗发生变化的拐点,二是同一软件同一模块运行不同任务时,所产生的数据样本数量级差异过大。基于此,提出一种结合FCM和LSTM的算法研究软件运行资源变化规律的方法,利用FCM算法实现不同数量级样本间的群聚,接着把处理后的样本放入LSTM模型进行训练,进而得到资源消耗变化曲线。实验表明,通过资源消耗变化曲线能够确定拐点的类型和其出现的位置区间,进而找到软件运行资源变化规律。另外,通过对比分析,FCM-LSTM模型在解决此问题上的准确率高于其他同类型的传统算法。

关键词：资源消耗 FCM LSTM 软件行为分析

Degradation of bisphenol-A using ultrasonic irradiation assisted by low-concentration hydrogen peroxide

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Journal of Environmental Sciences 2011年第1期23卷 31-36页

作者： kejia Zhang Naiyun Gao Yang Deng Tsair Fuh Lin Yan Ma Lei Li Minghao Sui State Key Laboratory of Pollution Control and Resource Reuse Tongji University Shanghai 200092 China Department of Earth and Environmental Studies Montclair State University Montclair New Jersey 07043 USA Department of Environmental Engineering and Sustainable Environment Research Center 'National' Cheng Kung University Tainan 70101 Taiwan

This study investigated the degradation of bisphenol-A （BPA） by ultrasonic irradiation in the presence of different additives （H2O2, air bubbles and humic acid） under various operating conditions, i.e., ultrasonic frequency, power intensity and power density. The results demonstrated that the BPA degradation followed pseudo first-order kinetics under different experimental conditions. The optimum power intensities were 0.9, 1.8, and 3.0 W/cm2 at the frequencies of 400, 670, and 800 kHz, respectively. At the fixed frequency （800 kHz）, the degradation rate of BPA was shown proportional to the increase of power density applied. With this manner, the BPA sonolysis could be facilitated at H202 dosage being lower than 0.1 mmol/L; while BPA degradation was hindered at H202 concentration in excess of 1 mmol/L. Additionally, BPA removal was shown to be inhibited by the presence of aeration and humic acid during ultrasonic irradiation. The present study suggested that the degradation rate of BPA assisted by ultrasonic irradiation was influenced by a variety of factors, and high BPA removal rate could be achieved under appropriate conditions.

关键词： bisphenol-A (BPA) ultrasonic irradiation power density additives

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基于斯卡那维模型的离子晶体介电性能的研究

人工晶体学报 2024年第6期53卷 991-998页

作者：罗昊成鹏飞党子妍耿可佳孔存存秦新瑞苏耀恒西安工程大学理学院西安710048

本文采用玻恩圆周轨道极化模型、双原子分子离子位移极化模型,分别计算了NaCl晶体中各离子的电子位移极化率和离子位移极化率。进一步采用点偶极子近似和双原子分子平均场近似,考虑在极化离子所产生的附加电场的作用下,基于斯卡那维模... 详细信息

本文采用玻恩圆周轨道极化模型、双原子分子离子位移极化模型,分别计算了NaCl晶体中各离子的电子位移极化率和离子位移极化率。进一步采用点偶极子近似和双原子分子平均场近似,考虑在极化离子所产生的附加电场的作用下,基于斯卡那维模型计算出包含不同离子数目的NaCl晶体的有效电场结构系数,得到了与实测值更为接近的介电常数,与将晶体内部的有效电场视为外施宏观平均电场的Born理论计算值进行对比,误差值从11.4%降至4.3%。研究结果提供了通过斯卡那维模型精确计算离子晶体介电性能的新思路。

关键词： NaCl晶体电子位移极化率离子位移极化率有效电场结构系数介电常数斯卡那维模型

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Influence of the amplitude ratio between two terahertz pulses on two-dimensional spectroscopy

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Chinese Science Bulletin 2014年第2期59卷 138-146页

作者： Jiangsheng Hu Jinsong Liu Huquan Li kejia Wang Zhengang Yang Shenglie Wang Wuhan National Laboratory for Optoelectronics School of Optical and Electronic Information Huazhong University of Science and Technology

The influence of the amplitude ratio between the two THz pulses on two-dimension THz spectroscopy(2DTS)has been studied theoretically via a classical method in which the expressions for the second-order nonlinearity were derived using perturbation approach,and the THz pulses were not treated as a delta *** types of nonlinear sources i.e.,anharmonicity,nonlinear damping,and nonlinear coupling,are considered in a single mode *** simulation results demonstrated that the amplitude ratio had a notable influence on the 2DTSs,and different sources have different *** study is promising for guiding future experiments.

关键词：太赫兹脉冲振幅比二维谱线性表达式非线性耦合非线性阻尼经典方法非线性源

The mediating role of organizational commitment between calling and work engagement of nurses: A cross-sectional study

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International Journal of Nursing Sciences 2019年第3期6卷 309-314页

作者： Yudi Cao Jingying Liu kejia Liu Mengyu Yang Yanhui Liu School of Nursing Tianjin University of Traditional Chinese MedicineChina

Objective: Nurse shortage is a critical problem for global healthcare *** impacts the quality of clinical *** engagement is the core competence of hospitals,which indicates employee's positive attitude toward organization and *** study aimed to explore the relationships among calling,organizational commitment,and work ***: A cross-sectional study was designed,and 320 nurses from tertiary hospitals in China completed the questionnaires that included demographic information,calling scale,employee engagement scale,and organizational commitment *** correlation was performed to test the correlations among calling,organizational commitment,and work *** regression analyses were performed to explore the mediating role of organizational *** bootstrap method was employed to confirm the mediating ***: Nurses' work engagement score was at the medium degree,whereas calling and organizational commitment were in the medium to high *** results revealed that calling,organizational commitment,work engagement,and each dimension were positively correlated with one another (r=0.145-0.922,P 0.01).The organizational commitment plays a partially mediating effect between calling and work engagement (β =0.603 to 0.333,P 0.01).Conclusions: The mediation effect of organizational commitment was verified,which provided a comprehensive understanding of how calling impacted work ***,administrators should not only promote interventions to increase work engagement but also pay attention to calling and organizational commitment so as to improve their work *** together,increased level of work engagement is required in the current nursing field.

关键词： Nurses Calling Employee engagement Organizational commitment

污水处理厂碳排放核算方法的标准研究与修正建议

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东华大学学报（自然科学版） 2024年第1期50卷 134-144页

作者：郑凯远陈红绳俊蔡冬清薛罡曾可佳于鑫叶沁辉东华大学环境科学与工程学院上海210620 东华大学土壤修复与固废资源化研究所上海210620 上海污染控制与生态安全研究院上海200092

对污水处理厂碳排放量的精准核算方法的标准进行研究。基于我国污水处理厂现有碳核算方法,结合国内外碳核算相关标准与指南,从核算边界、温室气体类型、排放源及排放过程等方面提出修正建议。建议在不引起重复计算的基础上,将核算边界... 详细信息

对污水处理厂碳排放量的精准核算方法的标准进行研究。基于我国污水处理厂现有碳核算方法,结合国内外碳核算相关标准与指南,从核算边界、温室气体类型、排放源及排放过程等方面提出修正建议。建议在不引起重复计算的基础上,将核算边界扩展到污水处理厂及上下游活动,包括上下游管网及下游自然水体;将污水与使用的药剂产生的化石性CO_(2)纳入核算;补充识别厂界内燃料燃烧、运输设备、无组织排放源,增加考虑委外运输、污泥处置的碳排放和多种能源(电力、热力等)、多物质(药剂等)在制造及运输环节的碳排放,并考虑污水处理运行工况对碳排放产生的波动影响。建议将污水处理厂优化运营管理及多元形式的资源能源回收途径纳入碳减排。在此基础上,总结了污水处理厂的碳排放过程及碳排放源。此外,从碳核算边界、排放因子、模型应用、化石性CO_(2)等方面对如何优化污水处理厂碳排放计算进行展望。

关键词：碳排放碳核算碳减排标准研究修正建议污水处理厂