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成人脊柱畸形多节段融合内固定术后假关节形成

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骨科动态 2006年第3期2卷 147-154页

作者： YONGJUNG J. KIM keith h. bridwell LAWRENCE G. LENKE KYU-JUNG Ch. Ch.RLES C. EDWARDS Ⅱ ANTh.NY S. RINELLA 白剑强（译）夏群（译）费礼起（校） Investigation performed at Wash.ngton University Medical Center St. Louis Missouri 天津市天津医院 300211

背景：自从现代脊柱内固定技术应用于临床以来，鲜有详细的关于成人脊柱畸形采用脊柱融合内固定术后假关节形成的报道。本研究的目的是分析成人脊柱融合内固定术后假关节形成的趋势、危险因素，并应用脊柱侧凸研究学会-24评价表对结果... 详细信息

背景：自从现代脊柱内固定技术应用于临床以来，鲜有详细的关于成人脊柱畸形采用脊柱融合内固定术后假关节形成的报道。本研究的目的是分析成人脊柱融合内固定术后假关节形成的趋势、危险因素，并应用脊柱侧凸研究学会-24评价表对结果进行评分。方法：对同一机构的232例手术治疗成人脊柱畸形的病例进行临床和影像学评估。患者平均年龄40．8岁，初次手术150例，翻修术82例。所有患者均接受了长节段（4个或4个以上椎体）的固定融合，至少有2年以上的随访。临床结果的评估采用脊柱侧凸协会的问卷调查表。结果：40例患者有假关节形成。与假关节形成有关的因素包括术前患者胸腰椎后凸大于20。（p〈0．0001）、年龄超过55岁（p〈0．001）、融合S，节段（相比融合L5或更近端的节段，p=0．002）、融合多于12个节段（p=0．037）。问卷调查得出的有假关节形成患者的评分平均低于无假关节形成患者的评分（p=0．001）。结论：用长节段的现代脊柱融合内固定治疗成人脊柱畸形后，假关节发生率为17％，且临床随访效果不满意。可信水平：预后性研究，Ⅱ级。详细的可信水平描述参见作者须知。

关键词：假关节形成内固定术后脊柱畸形多节段成人脊柱内固定技术影像学评估问卷调查表

Cancer risk in primary sclerosing ch.langitis: Epidemiology,prevention, and surveillance strategies

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World Journal of Gastroenterology 2019年第6期25卷 659-671页

作者： Brian M Fung keith D Lindor James h.Tabibian UCLA-Olive View Internal Medicine Residency Program Olive View-UCLA Medical Center Office of th. University Provost Arizona State University Division of Gastroenterology Department of MedicineOlive View-UCLA Medical Center

Primary sclerosing ch.langitis(PSC) is a rare ch.lestatic liver disease ch.racterized by progressive fibroinflammatory destruction of th. intra-and/or extrah.patic biliary ducts. Wh.le its features and disease course can be variable,most patients with.PSC h.ve concurrent inflammatory bowel disease and will eventually develop liver cirrh.sis and end-stage liver disease, with.liver transplantation representing th. only potentially curative option. Importantly,PSC is associated with.a significantly increased risk of malignancy compared to th. general population, mainly ch.langiocarcinoma, gallbladder carcinoma,h.patocellular carcinoma, and colorectal cancer, with.nearly 50% of death. in patients with.PSC being due to cancer. Th.refore, robust surveillance strategies are needed, th.ugh.uncertainty remains regarding h.w to best do so. In th.s review, we discuss th. epidemiology, prevention, and surveillance of cancers in patients with.PSC. Wh.re evidence is limited, we present pragmatic approach.s based on currently available data and expert opinion.

关键词： Bile duct diseases Ch.langiocarcinoma Gallbladder carcinoma h.patocellular carcinoma Colorectal cancer Ch.moprotection Inflammatory bowel disease

Esoph.geal lich.n planus:A case report and review of th. literature

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World Journal of Gastroenterology 2013年第14期19卷 2278-2281页

作者： Jennifer A Nielsen Robert M Law keith h.Fiman Cory A Roberts Division of Research ProPathDallasTX 75247United States Division of Dermatopath.logy ProPathDallas TX 75247United States Gastroenterology Consultants South.est LLP Sugar LandTX 77478United States Division of Gastrointestinal Path.logy ProPathDallasTX 75247United States

Esoph.geal involvement by lich.n planus(ELP),previously th.ugh. to be quite rare,is a disease much.more common in women and frequently th. initial manifestation of mucocutaneous lich.n planus(LP).Considering th.t th. symptoms of ELP do not present in a predictable manner,ELP is perh.ps more under-recognized th.n *** date,four cases of squamous cell carcinoma in association with.ELP h.ve been reported,suggesting th.t timely and accurate diagnosis of ELP is of importance for appropriate *** th.s case report,a 69-year-old female presented with.dysph.gia and *** reported a h.story of oral LP but h.d no active oral or skin *** examination revealed severe strictures and web-like areas in th. *** examination demonstratedextensive denudation of th. squamous epith.lium,scattered intraepith.lial lymph.cytes,rare eosinoph.ls and dyskeratotic *** immunofluorescence sh.wed rare cytoid bodies and was used to exclude oth.r primary immunobullous *** using clinical,endoscopic,and h.stologic data,a broad list of differential diagnoses can be narrowed,and th. accurate diagnosis of ELP can be made,wh.ch.is essential for proper treatment and subsequent follow-up.

关键词： Esoph.geal lich.n planus Esoph.gus Immunofluorescence Immunobullous disorders Diagnostic accuracy

Origin of th. Caribbean Plate Conference Siguenza, Spain, May 29-June 2, 2006

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Episodes 2006年第4期29卷 299-300页

作者： keith h. James Maria Antonieta Lorente h.norary Departmental Fellow Institute of Geograph. and Earth.Sciences University of Wales Aberystwyth.UK Stratigraph. Professor Postgraduate Program Universidad Central de Venezuela Caracas Venezuela

An international research.conference, entitled ＂Geology of th. area between North.and South.America, with.focus on th. origin of th. Caribbean Plate＂, took place in Siguenza, Spain, from May 29-June 2, 2006. Fifty five people from 11 countries attended th. meeting, wh.ch.was ch.ired by Drs. Albert W. Bally, Mafia Antonieta Lorente and David G. Roberts. Siguenza auth.rities and volunteers lent a great deal of enth.siastic support, wh.le BP, Repsol, Sh.ll, Statoil and SEPM provided financial encouragement.

关键词：加勒比海西班牙地质环境国际研究会议行业交流

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分布式计算系统在英国学术界的应用

计算机工程与应用 1992年第8期28卷 60-62页

作者： keith h. Bennet 杨宏戟英国达拉姆大学工程与计算机学院

英国学术界的分布计算系统可分为两个层次:在局部地区,大多数教学与科研机构的计算机系统都由局部网络连接起来;在全国范围内,各地区的局部网络又由“联合学术网”(Joint Academic Network——JANET)连接。本文将在这两个层次上介绍英... 详细信息

英国学术界的分布计算系统可分为两个层次:在局部地区,大多数教学与科研机构的计算机系统都由局部网络连接起来;在全国范围内,各地区的局部网络又由“联合学术网”(Joint Academic Network——JANET)连接。本文将在这两个层次上介绍英国分布式系统的现状和发展趋势。达拉姆大学即将装配的分布式计算机系统将作为一个实例同时介绍。

关键词：分布式计算系统英国应用

Increased ph.sical activity, ph.sician recommendation, and senior center participation

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h.alth 2013年第12期5卷 8-18页

作者： James h. Swan keith Turner Sh.lpa Sh.sh.dh.ra David Sanders Clinical Eth.cs Center Memorial Health System Springfield USA Department of Psych.logy Sociology and Social Work Angelo State University San Angelo USA Programs in Applied Gerontology University of North Texas Denton USA

Ph.sical activity is a recognized preventive h.alth.measure for seniors and an important focus for senior centers. Th.s paper employs th. Andersen Beh.vioral Model to explore increased ph.sical activity and participation in th.ee types of senior center activities: ph.sical fitness, dance/aerobic classes, and ch.ir exercises. Data were collected in 2006 on 798 and in 2007 on 742 participants at 21 multipurpose senior centers in a large urban county. Logistic regression analysis (PROC RLOGIST in SAS-callable SUDAAN) was employed to predict increased ph.sical activity, with.modes of center participation in ph.sical activity as mediating factors. Predisposing and enabling factors predicted both.engaging in center-based exercise programs and increases in ph.sical activity;but th. strongest predictors of increases in ph.sical activity were needed factors: ph.sician recommendations to increase exercise and to lose weigh.. Implications are th.t both.SCs and h.alth.are providers are important to promote ph.sical activity in th. older population.

关键词： Ph.sical Activity Senior Centers Ph.sician Recommendations Patient Compliance Andersen Beh.vioral Model

Th. Effect of Organo-Mineral Fertilizer Applications on th. Yield of Winter Wh.at, Spring Barley, Forage Maize and Grass Cut for Silage

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Journal of Environmental Protection 2015年第2期6卷 103-109页

作者： Grace h. Smith.keith Ch.ney Ch.rles Murray Minh.Son Le h.rper Adams University Newport UK United Utilities Group PLC Lingley Mere Business Park Warrington UK

Biosolids were applied with.urea to produce a granulated organo-mineral fertiliser (OMF) for application by farm fertiliser equipment to a range of agricultural crops. Th. recommended rates of nitrogen, ph.sph.te and potash.were calculated for th. test crops using “Th. Fertiliser Manual”, wh.ch.assesses th. nutrient requirement based on previous cropping, rainfall and soil index. Th. OMF produced similar crop yields compared to ammonium nitrate fertiliser wh.n applied as a top-dressing to winter wh.at, forage maize and grass cut for silage in th. cropping years 2010 to 2014. In 2012 th. grain yield of spring barley top-dressed with.OMF was significantly lower th.n th. conventional fertiliser treatment, due to dry conditions following application. For th.s reason it is recommended th.t OMF is incorporated into th. seedbed for spring sown crops and Th. Safe Sludge Matrix guidelines followed. Th. experimental work presented sh.ws th.t OMF can be used in sustainable crop production systems as a source of nitrogen and ph.sph.rus for a range of agricultural crops.

关键词： Biosolids Organo-Mineral Fertiliser Crop Yield Winter Wh.at Spring Barley Forage Maize Grass Silage

A Qualitative Assessment of a Modified Multilevel Converter Topology M2LeC for Ligh.weigh. Low-Cost Electric Propulsion

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Engineering（科研） 2020年第7期12卷 496-515页

作者： Paul h. Riley Obrad Dordevic keith Pullen Liliana DeLilo Massimo De Giorgio Sch.ol of Math.matics Computer Science and Engineering University of London London UK Department of Electronics and Electrical Engineering Liverpool John Moore University Liverpool UK Sch.ol of Engineering University of Nottingham Nottingham UK

A Cascade h.Bridge (Ch.) is evaluated for both.electric veh.cle motor traction control and off-veh.cle ch.rging against th. Power ElectronicsUK Automotive Ch.llenge for cost and mass for th. year 2035. By combining th. power electronics with.batteries using low-voltage MOSFET transistors in a series cascade arrangement th. cost and mass targets could be met 12 years earlier (in 2023 and 20 times ligh.er if an application specific integrated circuit (ASIC) is used. A 200 kW peak reference car was used to evaluate cost and mass benefits using four different topologies of power electronics. Veh.cle installation is sh.wn to be simplified as only passive cooling is required removing th. need for liquid cooling systems and th. arrangement is inh.rently safe;no h.gh.voltages are present wh.n th. veh.cle is stationary. Th. inh.rently h.gh.r efficiency of Ch. increases veh.cle range. Th. converter with.integrated batteries can also beh.ve as an integrated on-board battery ch.rger delivering additional off-veh.cle benefits by removing th. need for costly external ch.rgers.

关键词： Power Electronics Electric Veh.cles Cascaded h.Bridge Ch. Modular Multi-Level Converter MMC MLC

No difference in mortality among ALPPS,two-staged h.patectomy,and portal vein embolization/ligation:A systematic review by updated traditional and network meta-analyses

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h.patobiliary & Pancreatic Diseases International 2020年第5期19卷 411-419页

作者： Pasch.lis Gavriilidis Robert P Sutcliffe keith J Roberts Madh.va Pai Duncan Spalding Nagy h.bib Long R Jiao Mikael h.Sodergren Department of h.patopanceaticobiliary Surgery Imperial College Healthcare NHS TrustHammersmith HospitalLondon W120HSUK Department of h.pato-Pancreato-Biliary and Liver Transplant Surgery Queen Elizabeth University Hospitals Birmingham NHS Foundation TrustBirmingham B152THUK

Background:Th.re is an ongoing debate on th. feasibility,safety,and oncological efficacy of th. associating liver partition and portal vein ligation for staged h.patectomy(ALPPS)*** aim of th.s study was to compare ALPPS,two-staged h.patectomy(TSh.,and portal vein embolization(PVE)/ligation(PVL)using updated traditional meta-analysis and network meta-analysis(NMA).Data sources:Electronic databases were used in a systematic literature *** traditional metaanalysis and NMA were performed and *** and major morbidity were selected as primary ***:Nineteen studies including 1200 patients were selected from th. pool of 436 *** th.se patients,315(31%)and 702(69%)underwent ALPPS and portal vein occlusion(PVO),*** mortality based on updated traditional meta-analysis,subgroup analysis of th. randomized controlled trials(RCTs),and both.Bayesian and frequentist NMA did not demonstrate significant differences between th. ALPPS coh.rt and th. PVE,PVL,and TSh.***,analysis of RCTs did not demonstrate significant differences of major morbidity between th. ALPPS and PVO *** ALPPS coh.rt demonstrated significantly more favorable outcomes in h.pertroph. parameters,time to operation,definitive h.patectomy,and R0 margins rates compared with.th. PVO *** contrast,1-year disease-free survival was significantly h.gh.r in th. PVO coh.rt compared to th. ALPPS ***:Th.s study is th. first to use updated traditional meta-analysis and both.Bayesian and frequentist NMA and demonstrated no significant differences in 90-day mortality between th. ALPPS and oth.r h.patic h.pertroph. ***,two h.gh.quality RCTs including 147 patients demonstrated no significant differences in major morbidity between th. ALPPS and PVO coh.rts.

关键词： ALPPS h.patectomy Portal vein embolization Portal vein ligation Network meta-analysis