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The Land- Potential Knowledge System (LandPKS): mobile apps and collaboration for optimizing climate change investments

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Ecosystem Health and Sustainability 2016年第3期2卷 31-38页

作者： Jeffrey E.Herrick Adam Beh Edmundo Barrios Ioana Bouvier Marina Coetzee david dent Emile Elias Tomislav Hengl Jason W.Karl Hanspeter Liniger John Matuszak Jason CNeff Lilian Wangui Ndungu Michael Obersteiner keith d.shepherd Kevin C.Urama Rik van den Bosch Nicholas P.Webb U.S.department of Agriculture-Agricultural Research Service New Mexico State UniversityJornada Experimental Range MSC 3JERBox 30003Las CrucesNew Mexico 88003-8003 USA World Agroforestry Centre United Nations AvenueGigiriP.O.Box 30677Nairobi00100Kenya U.S.Agency for International development 3014th StreetSW SA-44(Rm 848)WashingtonD.C.20024 USA Namibia University of Science and Technology 13 Storch StreetPrivate Bag 13388WindhoekNamibia Merchants of Light Ltd Forncett EndNorfolkEngland ISRIC-World Soil information Droevendaalsesteeg 36708PB WageningenThe Netherlands Center for the development and Environment University of BernHallerstrasse 103012BernSwitzerland U.S.department of State/OES 2201 C St.NWWashingtonD.C.20520USA Environmental Studies Program University of Colorado at BoulderCampus Box 397BoulderColorado 80309 USA RCMRd SERVIR-Eastern&Southern AfricaP.O.Box 63200618 RuarakaNairobiKenya International Institute for Applied Systems Analysis Schlossplatz 1 A-2361LaxenburgAustria African development Bank Avenue Jean-Paul II01 BP 1387Abidjan 01Côte d’Ivoire

Massive investments in climate change mitigation and adaptation are projected during coming *** of these investments will seek to modify how land is *** return on both types of investments can be increased through an understanding of land potential:the potential of the land to support primary production and ecosystem services,and its resilience.A Land-Potential Knowledge System(LandPKS)is being developed and implemented to provide individual users with point-based estimates of land potential based on the integration of simple,geo-tagged user inputs with cloud-based information and *** system will rely on mobile phones for knowledge and information exchange,and use cloud computing to integrate,interpret,and access relevant knowledge and information,including local knowledge about land with similar *** system will initially provide management options based on long-term land potential,which depends on climate,to-pography,and relatively static soil properties,such as soil texture,depth,and *** mod-ules will provide more specific management information based on the status of relatively dynamic soil properties such as organic matter and nutrient content,and of *** paper includes a discus-sion of how this system can be used to help distinguish between meteorological and edaphic drought.

关键词： agriculture analytics crowdsourcing expert systems extension knowledge management land evaluation land-use planning mobile apps sustainability sustainable land management

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Hybridisation in kiwi(Apteryx;Apterygidae)requires taxonomic revision for the Great Spotted Kiwi

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Avian Research 2021年第2期12卷 195-207页

作者： Lara d.shepherd Alan J.d.Tennyson Hugh A.Robertson Rogan M.Colbourne Kristina M.Ramstad Museum of New Zealand Te Papa Tongarewa Wellington 6011New Zealand Biodiversity Group department of Conservation PO Box 10420Welling-ton 6011New Zealand department of Biology and Geology University of South Carolina Aiken471 University ParkwayAikenSC 29801USA

Background:Kiwi(Apteryx spp.)are flightless ratites from New Zealand whose numbers and distributions have declined following human *** of the kiwi species are known to hybridise but the extent of hybridization is ***:We reviewed hybridisation in kiwi(Apteryx spp.)and present new genetic data examining the extent of hybridisation between Rowi(***)and Little Spotted Kiwi(***)at Okarito,the location of the only remaining natural population of the threatened *** also genetically examined the syntype specimens of *** Potts,1872,collected from near Okarito in the 1870s,which have unusual ***:We found evidence of recurrent hybridisation between Rowi and Little Spotted Kiwi over the last 150 years,including one F1 hybrid found in the last 15 years,despite Little Spotted Kiwi’s likely extinction on the mainland in the ***,we found little evidence of introgression of Little Spotted Kiwi alleles into the extant Rowi *** syntype specimens of *** were also found to be hybrids between Little Spotted Kiwi and ***:Our genetic analyses indicate that,although we detected multiple instances of hybridisation between Rowi and Little Spotted Kiwi,it does not appear to be an ongoing threat to *** the syntype specimens of *** are hybrids and therefore not representative of the prevailing usage of the name for the Great Spotted Kiwi(***),we resurrect the nomen oblitum *** Sclater and Hochstetter,1861 for the large spotted kiwi species.

关键词： Apteryx Apteryx haastii dNA Hybridisation Kiwi Taxonomy

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Symptom presentation and evolution in the first 48 hours after injury are associated with return to play after concussion in elite Rugby Union

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Journal of Sport and Health Science 2024年第3期13卷 387-397页

作者： Ross Tucker Matt Cross keith Stokes Lindsay Starling Rosy Hyman Simon Kemp Stephen West Martin Raftery Eanna Falvey James Brown Institute of Sport and Exercise Medicine(ISEM) Department of ExerciseUniversity of StellenboschTygerberg 7505South Africa World Rugby Ltd. Dublin D02 AE93Ireland Premiership Rugby London SW1V 1PXUK Centre for Health and Injury and Illness Prevention in SportUniversity of BathClaverton Down BA27AYUK UK Collaborating Centre on Injury and Illness Prevention in Sport(UKCCIIS) University of BathClaverton Down BA27AYUK Rugby Football Union London TW27BAUK London School of Tropical Medicine London WC1E 7HTUK Sport Injury Prevention Research Centre Faculty of KinesiologyUniversity of CalgaryCalgary T2N 1N4Canada department of Medicine School of Medicine and HealthUniversity College CorkCork T12 EC8PIreland Carnegie Applied Rugby Research(CARR)centre Carnegie School of SportLeeds Beckett UniversityLeeds LS63QSUK

Background:Return to play(RTP)in elite rugby is managed using a 6-stage graduated RTP protocol,which can result in clearance to play within 1 week of *** aimed to explore how symptom,cognitive,and balance presentation and evolution during concussion screens 2 h(head injury assessment(HIA2)and 48 h(HIA3)after injury were associated with time to RTP)to identify whether a more conservative graduated RTP may be ***:A retrospective cohort study was conducted in 380 concussed rugby players from elite men’s rugby over 3 consecutive *** were classified as shorter or longer returns,depending on whether RTP occurred within 7 days(allowing them to be considered to play the match 1 week after injury)or longer than 8 days,***,cognitive,and balance performance during screens was assessed relative to baseline(normal or abnormal)and to the preceding screen(improving or worsening).Associations between sub-test abnormalities and RTP time were explored using odds ratios(OR,longer ***).Median day absence was compared between players with abnormal or worsening results and those whose results were normal or ***:Abnormal symptom results during screens 2 h and 48 h after concussion were associated with longer return time(HIA2:OR=2.21,95%confidence interval(95%CI):1.39-3.50;HIA3:OR=3.30,95%CI:1.89-5.75).Worsening symptom number or severity from the time of injury to 2 h and 48 h post-injury was associated with longer return(HIA2:OR=2.49,95%CI:1.36-4.58;HIA3:OR=3.34,95%CI:1.10-10.15).Median days absence was greater in players with abnormal symptom results at both HIA2 and *** and balance performance were not associated with longer return and did not affect median days ***:Symptom presentation and evolution within 48 h of concussion were associated with longer RTP *** may guide a more conservative approach to RTP,while still adhering to individualized concussion management principles.

关键词： Brain injury Concussion management General return to play Medical management

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EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors

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Signal Transduction and Targeted Therapy 2024年第2期9卷 679-692页

作者： keith Al-Hasani Safiya Naina Marikar Harikrishnan Kaipananickal Scott Maxwell Jun Okabe Ishant Khurana Thomas Karagiannis Julia J.Liang Lina Mariana Thomas Loudovaris Thomas Kay Assam El-Osta Epigenetics in Human Health and disease Program Baker Heart and Diabetes Institute75 Commercial RoadMelbourne 3004 VICAustralia department of diabetes Central Clinical SchoolMonash UniversityMelbourne 3004 VICAustralia Epigenetics in Human Health and disease Laboratory Central Clinical SchoolMonash UniversityMelbourne 3004 VICAustralia School of Science STEM CollegeRMIT UniversityMelbourne 3001 VICAustralia Immunology and diabetes Unit St Vincent’s Institute of Medical ResearchFitzroy 3065 VICAustralia department of Medicine and Therapeutics The Chinese University of Hong KongSha TinHong Kong SAR Hong Kong Institute of diabetes and Obesity Prince of Wales HospitalThe Chinese University of Hong Kong3/F Lui Che Woo Clinical Sciences Building30-32-Ngan Shing StreetSha TinHong Kong SAR Li Ka Shing Institute of Health Sciences The Chinese University of Hong KongSha TinHong Kong SAR Biomedical Laboratory Science Department of TechnologyFaculty of HealthUniversity College CopenhagenCopenhagenDenmark

β-cells are a type of endocrine cell found in pancreatic islets that synthesize,store and release *** type 1 diabetes(T1d),T-cells of the immune system selectively destroy the insulin-producingβ-*** of these cells leads to a lifelong dependence on exogenous insulin administration for ***,there is an urgent need to identify novel therapies that stimulateβ-cell growth and induceβ-cell *** and others have shown that pancreatic ductal progenitor cells are a promising source for regeneratingβ-cells for T1d owing to their inherent differentiation *** transcriptional suppression is refractory to exocrine reaction and tightly controls the regenerative potential by the EZH2 *** the present study,we show that transient stimulation of exocrine cells,derived from juvenile and adult T1d donors to the FdAapproved EZH2 inhibitors GSK126 and Tazemetostat(Taz)influence a phenotypic shift towards aβ-like cell *** transition from repressed to permissive chromatin states are dependent on bivalent H3K27me3 and H3K4me3 chromatin *** EZH2 is fundamental toβ-cell regenerative *** pancreatic ductal cells exhibit insulin production and secretion in response to a physiological glucose challenge ex *** pre-clinical studies underscore the potential of small molecule inhibitors as novel modulators of ductal progenitor differentiation and a promising new approach for the restoration ofβ-like cell function.

关键词： EZH2 struction inhibitors

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Tree structure and diversity shape the biomass of primary temperate mountain forests

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Forest Ecosystems 2024年第4期11卷 568-579页

作者： dheeraj Ralhan Ruffy Rodrigo Heather keith Annemiek Irene Stegehuis Jakob Pavlin Yumei Jiang Milos Rydval Juliana Nogueira Alexandre Fruleux Marek Svitok Martin Mikolas daniel Kozak Martin dusatko Pavel Janda Oleh Chaskovsky Catalin-Constantin Roibu Miroslav Svoboda Czech University of Life Sciences Prague Faculty of Forestry and Wood SciencesKamycka 129Suchdol16521 Praha 6Czech Republic department of Forest Science Biliran Province State UniversityBiliran6549Philippines Griffith Climate Action Beacon Griffith UniversityParklands DriveSouthportGold CoastQueensland4222Australia Laboratoire de Geologie IPSLCNRSUMR 8538Ecole Normale SuperieurePSL UniversityParisFrance Univ.Lille Institut Mines-TelecomUniv.ArtoisJuniaULR 4515LGCgELaboratoire de Genie Civil et Geo-EnvironnementF-59000LilleFrance department of Biology and General Ecology Faculty of Ecology and Environmental SciencesTechnical University in ZvolenMasaryka 2496001ZvolenSlovakia Institute of Forest Management Ukrainian National Forestry UniversityLvivUkraine Forest Biometrics Laboratory–Faculty of Forestry Stefan Cel Mare University of SuceavaUniversitații Street Number.13Suceava720229Romania

Primary forests are spatially diverse terrestrial ecosystems with unique characteristics,being naturally regenerative and heterogeneous,which supports the stability of their carbon storage through the accumulation of live and dead ***,little is known about the interactions between biomass stocks,tree genus diversity and structure across a temperate montane primary ***,we investigated the relationship between tree structure(variability in basal area and tree size),genus-level diversity(abundance,tree diversity)and biomass stocks in temperate primary mountain forests across Central and Eastern *** used inventory data from726 permanent sample plots from mixed beech and spruce across the Carpathian *** used nonlinear regression to analyse the spatial variability in forest biomass,structure,and genus-level diversity and how they interact with plot-level tree age,disturbances,temperature and *** found that the combined effects of genus and structural indices were important for addressing the variability in biomass across different spatial *** processes in disturbance regimes and uneven tree age support forest hete rogeneity and the accumulation of live and dead biomass through the natural regeneration,growth and decay of the forest *** complexities in basal area index,supporte d by genus-level abundance,positively influence total biomass stocks,which was modulated by tree age and *** forests showed higher tree density and basal area than mixed beech forests,though mixed beech still contributes significantly to biomass across *** heterogeneity was strongly influenced by complexities in forest composition(tree genus diversity,structure).We addressed the importance of primary forests as stable carbon stores,achieved through structure and *** such ecosystems is critical for ensuring the stability of the primary forest,carbon store and biodiversity into the future.

关键词： Biodiversity indicators Biomass carbon stock Ecosystem functioning Forest composition Primary forest structure Tree size distribution

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Effects of improved fallow with Sesbania sesban on maize productivity and Striga hermonthica infestation in Western Kenya

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Journal of Forestry Research 2010年第3期21卷 379-386,400页

作者： Hans Sjogren keith d.shepherd Anders Karlsson department of Forest Ecology and Management Swedish University of Agricultural Sciences World Agroforestry Centre (ICRAF)

Striga hermonthica is a major constraint to smallholder sub-sistence agriculture production in the sub-Saharan African region. Low soil fertility and overall environmental degradation has contributed to the build-up of the parasitic weed infestation. Improved cropping systems have to be introduced to address the interrelated problems of S. her-monthica and soil fertility decline. Thus, the effects of improved fallow with leguminous shrub Sesbania sesban on maize yields and levels of S. hermonthica infestation on farm land in the bimodal highlands of western Kenya were investigated. The experimental treatments were arranged in a phased entry, and randomized complete block scheme were six months Sesbania fallow, 18 months Sesbania fallow, six months natural fallow consisting of regrowth of natural vegetation without cultivation, 18 months natural fallow, continuous maize cropping without fertilizer application, and continuous maize cropping with P and N fertilization. Results show that Sesbania fallows significantly （p0.05） increase maize yield relative to continuous unfertilized maize. S. hermonthica plant populations decrease in continuous maize between the first season （mean = 428 000 ± 63 000 ha-1） and second season （mean=51 000 ± 15 000 ha-1）, presumably in response to good weed management. S. hermonthica seed populations in the soil decrease throughout the duration of the experi-ment in the continuous maize treatments. Short-duration Sesbania fal-lows can provide modest yield improvements relative to continuous unfertilized maize, but short-duration weedy fallows are ineffective. Continuous maize cultivation with good weed control may provide more effective S. hermonthica control than fallowing.

关键词： agroforestry crop yield improved fallow residual effect root parasite soil fertility replenishment

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Paleoecological Response of Corals to the End-Triassic Mass Extinction： An Integrational Analysis

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Journal of Earth Science 2018年第4期29卷 879-885页

作者： George d Stanley Jr Hannah M E shepherd Autumn J Robinson University of Montana Paleontology Center Missoula MT 59812 USA

The end-Triassic （also Triassic-Jurassic） mass extinction severely affected life on planet Earth 200 million years ago. Paleoclimate change triggered by the volcanic eruptions of the Central Atlantic Magmatic Province （CAMP） caused a great loss of marine biodiversity, among which 96% coral genera were get lost. However, there is precious little detail on the paleoecology and growth forms lost between the latest Triassic extinction and the Early Jurassic recovery. Here a new pilot study was conducted by analyzing corallite integration levels among corals from the latest Triassic and Early Jurassic times. Integration levels in corals from the Late Triassic and Early Jurassic were determined through both the Paleobiology database as well as from a comprehensive museum collection of fossil corals. Results suggest that in addition to a major loss of diversity following the end-Triassic mass extinction, there also was a significant loss of highly integrated corals as clearly evidenced by the coral data from the Early Jurassic. This confirms our hypothesis of paleoecological selectivity for corals following the end-Triassic mass extinction. This study highlights the importance of assigning sim- ple to advanced paleoecological characters with integration levels, which opens a useful approach to understanding of mass extinction and the dynamics of the recovery.

关键词： coral loss integration level end-Triassic mass extinction paleoecology

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Attribution of Fano resonant features to plasmonic particle size, lattice constant, and dielectric wavenumber in square nanoparticle lattices

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Photonics Research 2014年第1期2卷 15-23页

作者： drew deJarnette Justin Norman d.keith Roper Microelectronics and Photonics Graduate Program University of ArkansasFayettevilleArkansas 72701USA department of Chemical Engineering University of ArkansasFayettevilleArkansas 72701USA

Fano resonances between plasmons and diffracted light offer tunable energies and locales,but attribution of Fano resonance features to geometry and physicochemistry of metal nanostructures and adjacent dielectrics has been confounded by complexity and computational *** work shows predictable modal shifts of Fano resonance in square lattices of plasmonic nanostructures can be attributed directly to changes in medium wavenumber,particle size,and lattice constant that alter plasmon polarizability and diffractive *** 45 to 80 nm radius particles,a window of lattice constants that support Fano resonances is identified in a range from 500 to 900 *** constants that support high intensity resonances are determined by individual particle polarizability and medium *** resonance wavelengths redshift from diffracted photon energies as local refractive index(RI)changes due to coupling with particle polarizability in the *** sensitivities for quadrupole,dipole,and Fano resonances are 150,348,and 541 nm,respectively,per RI *** resonance intensity may be enhanced more than tenfold by selecting nanoparticle sizes and lattice *** quantitative effects of such parametric changes are rapidly and intuitively distinguished using a semi-analytic approach,consisting of an exact expression for particle polarizability,a trigonometric description of diffraction,and a semianalytical coupled dipole approximation.

关键词： lattice particle wave

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ANALYZING MARKET COMPETITION BETWEEN AIRBUS ANd BOEING USING A dUO HIERARCHICAL GRAPH MOdEL FOR CONFLICT RESOLUTION

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Journal of Systems Science and Systems Engineering 2017年第6期26卷 683-710页

作者： He, Shawei Hipel, keith W. Kilgour, d. Marc College of Economics & Management Nanjing University of Aeronautics and Astronautics Nanjing China department of Systems design Engineering University of Waterloo Waterloo Canada Centre for International Governance Innovation Waterloo Canada Balsillie School of International Affairs Waterloo Canada department of Mathematics Wilfrid Laurier University Waterloo Canada

A duo hierarchical graph model for conflict resolution is developed to investigate market competition between Airbus and Boeing over aircraft sales in the Asia Pacific region. The duo hierarchical graph model, a significant extension of the graph model for conflict resolution methodology, contains two common decision makers, who take part in two related subconflicts, as well as local decision makers, who participate in only one subconflict. New stability definitions are proposed to describe forms of sanction unique to the hierarchical model. The interrelationships between stabilities in the overall graph model and in the two local models are investigated. Then the duo hierarchical graph model is applied to the competition between Airbus and Boeing in both the wide and narrow body markets in the Asia-Pacific region. The two types of Asian airlines have different operating strategies, so that the two markets constitute sub-competitions that can be modelled naturally using the duo hierarchical graph model. The stability results indicate a resolution for all decision makers that implies marketing strategies for the aircraft manufacturers and guidelines for aircraft purchase by the airlines. Thus, this model provides decision makers with a comprehensive understanding of the dynamics of the comoetition and guidance in identifving beneficial actions.

关键词： Hierarchical Graph Model Airbus and Boeing stability results strategic resolutions

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Prehospital transdermal glyceryl trinitrate for ultra- acute ischaemic stroke: data from the RIGHT- 2 randomised sham- controlled ambulance trial

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Stroke & Vascular Neurology 2024年第1期9卷 38-49,I0035-I0046页

作者： Jason Philip Appleton Lisa J Woodhouse Craig S Anderson Sandeep Ankolekar Lesley Cala Mark dixon Timothy J England Kailash Krishnan Grant Mair keith W Muir John Potter Christopher I Price Marc Randall Thompson G Robinson Christine Roffe Else C Sandset Jeffrey L Saver Angela Shone Aloysius Niroshan Siriwardena Joanna M Wardlaw Nikola Sprigg Philip M Bath Stroke University Hospitals Birmingham NHS Foundation TrustBirminghamUK Institute of Applied HealthResearch University of Birmingham College of Medical and Dental SciencesBirminghamUK Stroke Trials Unit Mental Health and Clinical NeurosciencesUniversity of NottinghamNottinghamUK Faculty of Medicine The George Institute for Global HealthSydneyNew South WalesAustralia The George Institute China at Peking University Health Science Center BeijingChina Neurology Royal Prince Alfred HospitalSydney Health PartnersSydneyNew South WalesAustralia department of Neurology King's College Hospital NHS Foundation TrustLondonUK Faculty of Health and Medical Sciences University of Western AustraliaCrawleyWestern AustraliaAustralia East Midlands Ambulance Service NHS Trust NottinghamUK Stroke Queen's Medical CentreNottingham University Hospitals NHS TrustNottinghamUK Centre for Clinical Brain Sciences Dementia Research InstituteUniveristy of EdinburghEdinburghUK Institute of Neurology and Psychology University of GlasgowGlasgowUK Bob Champion Research and Education Building University of East AngliaNorwichUK Institute of Neuroscience Newcastle UniversityNewcastle upon TyneUK department of Neurology Leeds Teaching Hospitals NHS TrustLeedsUK department of Cardiovascular Sciences and NIHR Leicester Biomedical Research Centre University of LeicesterLeicesterUK Stroke Research in Stoke Institute for Science and Technology in MedicineKeele UniversityStoke-on TrentUK department of Neurology Oslo University HospitalOsloNorway Research and development Norwegian Air Ambulance FoundationOsloNorway department of Neurology and Comprehensive Stroke Center David Geffen School of MedicineUCLALos AngelesCaliforniaUSA Research and Graduate Services University of NottinghamNottinghamUK Community and Health Research Unit University of LincolnLincolnUK

Background The effect of transdermal glyceryl trinitrate(GTN,a nitrovasodilator)on clinical outcome when administered before hospital admission in suspected stroke patients is ***,we assess the safety and efficacy of GTN in the prespecified subgroup of patients who had an ischaemic stroke within the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2(RIGHT-2).Methods RIGHT-2 was an ambulance-based multicentre sham-controlled blinded-endpoint study with patients randomised within 4hours of *** primary outcome was a shift in scores on the modified Rankin scale(mRS)at day *** outcomes included death;a global analysis(Wei-Lachin test)containing Barthel Index,EuroQol-5d,mRS,telephone interview for cognitive status-modified and Zung depression scale;and neuroimaging-determined‘brain frailty’*** were reported as n(%),mean(Sd),median[IQR],adjusted common OR(acOR),mean difference or Mann-Whitney difference(MWd)with 95%*** 597 of 1149(52%)patients had a final diagnosis of ischaemic stroke;age 75(12)years,premorbid mRS>2107(18%),Glasgow Coma Scale 14(2)and time from onset to randomisation 67[45,108]***‘brain frailty’was common:median score 2[2,3](range 0–3).At day 90,GTN did not influence the primary outcome(acOR for increased disability 1.15,95%CI 0.85 to 1.54),death or global analysis(MWd 0.00,95%CI-0.10 to 0.09).In subgroup analyses,there were non-significant interactions suggesting GTN may be associated with more death and dependency in participants randomised within 1hour of symptom onset and in those with more severe *** In patients who had an ischaemic stroke,ultra-acute administration of transdermal GTN in the ambulance did not improve clinical outcomes in a population with more clinical and radiological frailty than seen in previous in-hospital *** IS ALREAdY KNOWN ON THIS TOPIC⇒Transdermal glyceryl trinitrate(GTN)was associat-ed with less death and dependency in those w

关键词： Glasgow nitrate random

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