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Rectal angiolipoma diagnosed after surgical resection: A case report

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World Journal of Gastroenterology 2007年第3期13卷 467-469页

作者： Mitsuru Ishizuka Hitoshi Nagata Kazutoshi Takagi Toru Horie Akihito abe keiichi Kubota Department of Gastroenterological Surgery Dokkyo University School of Medicine Tochigi Japan

Angiolipoma is a common benign tumor with a char- acteristic vascular component that usually occurs in subcutaneous tissue. Although lipomas are frequently encountered at colonoscopy as submucosal tumors, an- giolipomas are rarely found in the gastrointestinal tract including the large intestine. Here we report a 77-year old Japanese man who underwent transanal resection of a tumor that was diagnosed tentatively as a leiomyoma. Histologically, the tumor consisted of mature fat cells and blood vessels. Immunohistochemically, the tumor cells were negative for c-kit and HMB-45, which are consis- tently expressed in tumors such as gastrointestinal stro- mal tumor and angiomyolipoma. The tumor was there- fore diagnosed as an angiolipoma. This is thought to be the first case report of a surgically resected angiolipoma of the rectum.

关键词： Angiolipoma Angiomyolipoma Gastrointestinal stromal tumor

Curative resection with endoscopic submucosal dissection of early gastric cancer in Helicobacter pylori-negative Ménétrier’s disease:A case report

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World Journal of Gastroenterology 2022年第5期28卷 594-601页

作者： Koh Fukushi Kenichi Goda Hitoshi Kino Masayuki Kondo Mimari Kanazawa Ken Kashima Akira Kanamori keiichiro abe Tsunehiro Suzuki keiichi Tominaga Hidetsugu Yamagishi Atsushi Irisawa Department of Gastroenterology Dokkyo Medical UniversityMibu 321-0293TochigiJapan Department of Diagnostic Pathology Dokkyo Medical UniversityMibu 321-0293TochigiJapan

BACKGROUND Adult-onset Ménétrier’s disease is strongly associated with Helicobacter pylori(***)infection and an elevated risk of *** of early-stage gastric cancer developed in ***-negative Ménétrier’s disease are extremely *** report a case of early gastric cancer in ***-negative Ménétrier’s disease that was curatively resected with endoscopic submucosal dissection(ESD).CASE SUMMARY A 60-year-old woman was referred to our hospital after her medical examination detected ***-enhanced upper gastrointestinal(UGI)radiography revealed translucency of the nodule-aggregating surface with giant *** tests showed hypoproteinemia and were negative for serum *** immunoglobulin G *** 99mTc-DTPA-human serum albumin scintigraphy showed protein loss from the *** endoscopy showed a 40-mm protruding erythematous lesion on giant rugae of the greater curvature of lower gastric body,suggesting early-stage gastric cancer due to Ménétrier’s *** bloc resection with ESD was performed for diagnosis and *** of ESD showed well-differentiated tubular *** cancer was confined to the mucosa,and complete curative resection was *** hyperplasia and atrophy of the gastric glands were observed in non-tumor areas,histologically corresponding to Ménétrier’s *** years after ESD,gastric cancer had not recurred,and Ménétrier’s disease remained in remission with spontaneous regression of giant gastric *** Complete curative resection was achieved through ESD in a patient with earlystage gastric cancer and ***-negative Ménétrier’s disease.

关键词： Ménétrier’s disease Helicobacter pylori Gastric cancer Endoscopic resection Endoscopic submucosal dissection Case report

Case Report: Anaplastic Astrocytoma Treated with Postoperative Radiotherapy Using Flattening Filter-Free Volumetric Arc Therapy (FFF-VMAT) during Pregnancy—Acceptable Fetal Dosimetry

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Journal of Cancer Therapy 2020年第11期11卷 738-744页

作者： Tomoyuki Noyama Wataru Takahashi Yuki Nozawa Kanabu Nawa Hideomi Yamashita Osamu abe keiichi Nakagawa Department of Radiology The University of Tokyo Hospital Bunkyo-ku Tokyo Japan

Background: Postoperative irradiation for brain tumor in pregnant women is a matter of concern. Aim: We aimed to assess the safety of radiotherapy for brain tumors in pregnancy. We here report a successful treatment for anaplastic astrocytoma during pregnancy: surgery + postoperative irradiation. We wish to emphasize how we devised irradiation procedure to achieve both therapeutic effectiveness and safety to the fetus/infant. Case Presentation: A 34-year-old pregnant woman suffered with brain anaplastic astrocytoma. Tumor resection under craniotomy was performed with success. We decided to conduct postoperative radiotherapy at 25 weeks of gestation to reduce the risk of recurrence. We used a flattening filter-free volumetric arc therapy (FFF-VMAT) technique, which can achieve lower out-of-field dose than VMAT with a flattening filter or helical tomotherapy. We prescribed 60 Gy over 30 fractions. During actual beam delivery, surface and rectal dose to the patient (mother) were measured. The total fetal dose was estimated at 0.006 - 0.018 Gy, which is under the threshold set by the ICRP. A male healthy infant was born vaginally at the 37th week of pregnancy. The patient (mother) and the infant are healthy at the time of writing. Conclusion: FFF-VMAT is a good choice for brain tumors during pregnancy.

关键词： Pregnancy Radiotherapy Flattening Filter-Free Volumetric Arc Therapy An-aplastic Astrocytoma Fetal Dose

Whole circumferential endoscopic submucosal dissection of superficial adenocarcinoma in long-segment Barrett's esophagus:A case report

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World Journal of Gastrointestinal Surgery 2021年第10期13卷 1285-1292页

作者： keiichiro abe Kenichi Goda Akira Kanamori Tsunehiro Suzuki Akira Yamamiya Yoichi Takimoto Takahiro Arisaka Koki Hoshi Takeshi Sugaya Yuichi Majima keiichi Tominaga Makoto Iijima Shinichi Hirooka Hidetsugu Yamagishi Atsushi Irisawa Department of Gastroenterology Dokkyo Medical UniversityMibu 321-0293TochigiJapan Department of Pathology The Jikei University School of MedicineNishishimbashi 105-8471TokyoJapan Academic Institutional Research Center Dokkyo Medical UniversityMibu 321-0293TochigiJapan

BACKGROUND Esophageal adenocarcinoma(EAC)derived from long-segment Barrett’s esophagus(LSBE)is extremely rare in ***-related EAC is often difficult to diagnose in the horizontal *** the tumor has spread throughout the LSBE,whole circumferential endoscopic submucosal dissection(ESD)should be performed,which is difficult to complete ***,whole circumferential ESD can bring refractory postoperative *** hereby report a case of EAC involving the whole circumference of the LSBE,achieving complete endoscopic removal without *** SUMMARY An 85-year-old man with the chief complaint of dysphagia underwent *** suspected a flat-type cancerous lesion that extended the whole circumference of the LSBE(C 3.5,M 4.0)using narrow-band imaging magnification endoscopy(NBI-M).We achieved circumferential en bloc resection of the lesion safely with special ESD *** of the ESD specimens demonstrated that the superficial EAC extended the whole circumference of the LSBE,and papillary or well-differentiated tubular adenocarcinoma was confined in the lamina propria mucosa showing a vertical negative *** prevent post-ESD stenosis,we performed endoscopic local injection of steroids,followed by oral administration of *** was no evidence of esophageal refractory stenosis or tumor recurrence 30 mo after *** summary,we experienced a rare case of LSBE-related *** horizontal tumor extent was accurately diagnosed by ***,we achieve whole circumferential ESD safely without postoperative refractory *** NBI-M,ESD,and steroid therapy enabled the curative resection of superficial full circumferential LSBE-related EAC without refractory postoperative stenosis.

关键词： Endoscopic submucosal dissection Long-segment Barrett's esophagus Superficial esophageal adenocarcinoma Steroid Magnification endoscopy Case report

Stratifying the risk of lymph node metastasis in undifferentiated-type early gastric cancer

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World Journal of Gastroenterology 2015年第9期21卷 2683-2692页

作者： Yukiko Asakawa Masahiko Ohtaka Shinya Maekawa Mitsuharu Fukasawa Yasuhiro Nakayama Tatsuya Yamaguchi Taisuke Inoue Tomoyoshi Uetake Minoru Sakamoto Tadashi Sato Yoshihiko Kawaguchi Hideki Fujii Kunio Mochizuki Masao Hada Toshio Oyama Tomotaka Yasumura Kosaku Omata Atsushi Nishiyama keiichi Naito Hideo Hata Yoshiaki Haba Kazuyuki Miyata Haruhisa Saitoh Yoichi Yamadera Kazuo Miura Akira Kawaoi Tohru abe Hajime Tsunoda Yuji Honda Masayuki Kurosaki Nobuyuki Enomoto First Department of Internal Medicine Faculty of MedicineUniversity of YamanashiYamanashi 409-3898Japan First Department of Surgery Faculty of MedicineUniversity of YamanashiYamanashi 409-3898Japan Department of Pathology Faculty of MedicineUniversity of YamanashiYamanashi 409-3898Japan Department of Surgery Yamanashi Prefectural Central HospitalYamanashi 400-8506Japan Department of Pathology Yamanashi Prefectural Central HospitalYamanashi 400-8506Japan Department of Surgery Social Insurance Yamanashi HospitalYamanashi 400-0025Japan Department of Pathology Social Insurance Yamanashi HospitalYamanashi 400-0025Japan Department of General Surgery Kofu Kyoritsu HospitalYamanashi 400-0034Japan Department of Pathology Kofu Kyoritsu HospitalYamanashi 400-0034Japan Department of Surgery Kofu Municipal HospitalYamanashi 400-0832Japan Department of Pathology Kofu Municipal HospitalYamanashi 400-0832Japan Department of Surgery Yamanashi Kosei HospitalYamanashi 405-0033Japan Department of Surgery Kanoiwa General HospitalYamanashi 405-0018Japan Department of Pathology Kanoiwa General HospitalYamanashi 405-0018Japan Department of Surgery Social Insurance Kajikazawa HospitalYamanashi 400-0601Japan Department of Surgery Kofu National HospitalYamanashi 400-0006Japan Department of Surgery Fujiyoshida Municipal Medical CenterYamanashi 403-0005Japan Division of Gastroenterology and Hepatology Musashino Red Cross HospitalTokyo 180-0023Japan

AIM:To study how lymph node metastasis(LNM) risk is stratified in undifferentiated-type early gastric cancer(undiff-EGC) dependent on combinations of risk ***:Five hundred and sixty-seven cases with undiff-EGC undergoing gastrectomy with lymphadenectomy were examined *** clinicopathological factors of patient age,location,size,an endoscopic macroscopic tumor form,ulceration,depth,histology,lymphatic involvement(LI) and venous involvement(VI),LNM risk was examined and stratified by conventional statistical analysis and datamining ***:LNM was positive in 44 of 567 cases(7.8%).Univariate analysis revealed > 2 cm,protrusion,submucosal(sm),mixed type,LI and VI as significant prognostic factors and > 2 cm and LI-positive were independent factors by multivariate *** preoperatively evaluable factors excluding LVI,sm and > 2 cm were independent *** to the depth and size,cases were categorized into the low-risk group [m and ≤ 2 cm,0%(LNM incidence)],the moderaterisk group(m and > 2 cm,5.6%; and sm and ≤ 2 cm,6.0%),and the high-risk group(sm and > 2 cm,19.3%).On the other hand,LNM occurred in 1.4% in all LI-negative cases,greatly lower than 28.2% in all LI-positive cases,and LNM incidence was low in LInegative cases even in the moderate- and high-risk ***:LNM-related factors in undiff-EGC were depth and size preoperatively while those were LI and size *** these factors,LI was the most significantly correlated factor.

关键词： Undifferentiated-type early gastric cancer Lymph n