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Solitary extraovarian primary peritoneal carcinoma with direct invasion into the liver,diaphragm and lung without peritoneal dissemination or distant metastasis

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Hepatobiliary & Pancreatic Diseases International 2024年第3期23卷 322-325页

作者： Billy Ho Hung cheung Wong hoi She Siu Lun Ho Albert Chi Yan Chan Chung Mau Lo Tan To cheung Department of Surgery The University of Hong KongHong KongChina Department of Pathology The University of Hong KongHong KongChina

To the Editor:Extraovarian primary peritoneal carcinoma(EOPPC)is an uncommon malignancy with many similarities to epithelial ovarian carcinoma in histological,clinical,and etiological aspects[1].This phenomenon is explained by their common embryonal origin,in which both develop from the coelomic epithelium in the early embryological *** their similarities,the incidence of EOPPC is significantly lower than that of epithelial ovarian carcinoma(6.78 cases per million vs.120.5 cases per million)[1].

关键词： peritoneal invasion metastasis

Post-fontan circulation hepatocellular carcinoma:Open and laparoscopic hepatectomy

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Hepatobiliary & Pancreatic Diseases International 2024年第1期23卷 90-93页

作者： Karin KY Ho Wong hoi She Simon HY Tsang Kevin S Lo Tan To cheung Department of Surgery The University of Hong Kong102 Pok Fu Lam RoadHong KongChina Department of Anaesthesiology Queen Mary Hospital102 Pok Fu Lam RoadHong KongChina

To the Editor:Fontan-associated liver disease shows increasing incidence as advances in pediatric cardiology have prolonged life expectancy in patients with single ventricle congenital heart defects[1].Their unique physiology and procedure-related sequelae present an increasingly relevant challenge in hepatic *** hereby reported a series of patients suffering from hepatocellular carcinoma(HCC)who successfully underwent open and laparoscopic hepatectomy.

关键词： hepatocellular hepatectomy surgery

High Microplastic Contamination in Juvenile Tri-Spine Horseshoe Crabs:A Baseline Study of Nursery Habitats in Northern Beibu Gulf,China

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Journal of Ocean University of China 2022年第3期21卷 521-530页

作者： WANG Xueping LO hoi Shing FU Yijian WU Zhou QIN Danmei HUANG Xing ZHU Jingmin cheung Siu Gin KWAN Kit Yue College of Marine Sciences Beibu Gulf UniversityQinzhou535011China Guangxi Key Laboratory of Marine Disaster in the Beibu Gulf Qinzhou535011China Department of Chemistry City University of Hong KongHong Kong SARChina State Key Laboratory of Marine Pollution City University of Hong KongHong Kong SARChina Guangxi Key Laboratory of Beibu Gulf Marine Biodiversity Conservation Qinzhou535011China

Microplastics(MPs)are ubiquitous in marine sedimentary *** occurrence in horseshoe crabs and interactions with the sedimentary environment has not been *** this study,MPs,mostly microfibers,were found in all extracted gastrointestinal tract(GIT)samples of the juvenile Tachypleus tridentatus from the northern Beibu Gulf,*** MP concentrations(4–53 items ind-1)were higher than those in most marine benthic invertebrates(<15 items ind-1)reported in Chinese waters,despite their generally low level in habitat sediments(9–1818 items kg-1).The correlation between the juveniles and sediments was not evident,but the abundance in juvenile horseshoe crab GITs decreased with *** findings were relevant to the life-history characteristics of the species,typically with limited dispersal capability and their spending nine years or longer time living in mangrove wetlands during low tides,with apparent ontogenetic changes in their *** baseline data enable a better understanding of MP availability in benthic macroinvertebrates,and the ecological risks present in the ecosystems.

关键词： horseshoe crab invertebrate fiber intertidal cellophane

Recurrent pyogenic cholangitis:An indication for liver transplantation

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Hepatobiliary & Pancreatic Diseases International 2022年第4期21卷 396-398页

作者： Wong hoi She Wing Chiu Dai James YY Fung Tan To cheung Albert CY Chan Chung Mau Lo Department of Surgery The University of Hong Kong102 Pok Fu Lam RoadHong KongChina

To the Editor:Recurrent pyogenic cholangitis(RPC),also known as Hong Kong disease[1],is an unique disease entity with a decreasing *** is characterized by the formation of intrahepatic biliary pigmented stones,which r... 详细信息

关键词： cholangitis obstruction liver

Acute pancreatitis induced by transarterial chemoembolization:a single-center experience of over 1500 cases

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Hepatobiliary & Pancreatic Diseases International 2016年第1期15卷 93-98页

作者： Wong hoi She Albert CY Chan Tan To cheung Kenneth SH Chok See Ching Chan Ronnie TP Poon Chung Mau Lo Division of Hepatobiliary & Pancreatic Surgery and Liver Transplantation Department of SurgeryThe University of Hong Kong

BACKGROUND： Acute pancreatitis is a relatively rare but po- tentially lethal complication after transarterial chemotherapy. This study aimed to review the complications such as acute pancreatitis after transarterial chemotherapy with or without embolization for hepatocellular carcinoma. METHODS： A total of 1632 patients with hepatocellular car- cinoma who had undergone transarterial chemoembolization from ]anuary 2000 to February 2014 in a single-center were reviewed retrospectively. We investigated the potential com- plications of transarterial chemoembolization, such as acute pancreatitis and acute pancreatitis-related complications. RESULTS： Of the 1632 patients with hepatocellular carcinoma who had undergone 5434 transarterial chemoembolizations, 1328 were male and 304 female. The median age of these pa- tients was 61 years. Most （79.6%） of the patients suffered from HBV-related hepatoceUular carcinoma. The median tumor size was 5.2 cm. Of the 1632 patients, 145 patients underwent transarterial chemoembolization with doxorubicin elut- ing bead, making up a total of 538 episodes. The remaining patients underwent transarterial chemoembolization with cisplatin. Seven （0.4%） patients suffered from acute pancre- atitis post-chemoembolization. Six patients had chemoembo- lization with doxorubicin and one had chemoembolization with cisplatin. Patients who received doxornbicin eluting bead had a higher risk of acute pancreatitis [6/145 （4.1%） vs 1/1487 （0.1%）, P〈0.0001]. Two patients had anatomical arterial variations. Four patients developed acute pancreatitis- related complications including necrotizing pancreatitis （n=3） and pseudocyst formation （n=1）. All of the 4 patients resolved after the use of antibiotics and other conservative treatment. Three patients had further transarterial chemoembolization without any complication. CONCLUSIONS： Acute pancreatitis after transarterial chemo- embolization could result in serious complications, especially after treatment wit

关键词： transarterial chemoembolization acute pancreatitis hepatocellular carcinoma

Seismic performance of cable-sliding friction bearing system for isolated bridges

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Earthquake Engineering and Engineering Vibration 2012年第2期11卷 173-183页

作者： cheung Pakchiu State Key Laboratory of Disaster Reduction in Civil Engineering Tongji University

During past strong earthquakes, highway bridges have sustained severe damage or even collapse due to excessive displacements and/or very large lateral forces. For commonly used isolation bearings with a pure friction sliding surface, seismic forces may be reduced but displacements are often unconstrained. In this paper, an alternative seismic bearing system, called the cable-sliding friction bearing system, is developed by integrating seismic isolation devices with displacement restrainers consisting of cables attached to the upper and lower plates of the bearing. Restoring forces are provided to limit the displacements of the sliding component. Design parameters including the length and stiffness of the cables, friction coefficient, strength of the shear bolt in a fixed-type bearing, and movements under earthquake excitations are discussed. Laboratory testing of a prototype bearing subjected to vertical loads and quasi-static cyclic lateral loads, and corresponding numerical finite element simulation analysis, were carried out. It is shown that the numerical simulation shows good agreement with the experimental force-displacement hysteretic response, indicating the viability of the new bearing system. In addition, practical application of this bearing system to a multi-span bridge in China and its design advantages are discussed.

关键词： isolated bridge cable-sliding friction bearing isolation device seismic performance restrained displacement earthquake damage

Indications of pro-inflammatory cytokines in laparoscopic and open liver resection for early-stage hepatocellular carcinoma

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Hepatobiliary & Pancreatic Diseases International 2024年第3期23卷 257-264页

作者： Kevin Tak-Pan Ng Li Pang Jia-Qi Wang Wong hoi She Simon Hing-Yin Tsang Chung Mau Lo Kwan Man Tan To cheung Department of Surgery HKU-SZH&School of Clinical MedicineLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongChina State Key Laboratory of Liver Research The University of Hong KongHong KongChina

Background:Our clinical practice of laparoscopic liver resection(LLR)had achieved better short-term and long-term benefits for patients with hepatocellular carcinoma(HCC)over open liver resection(OLR),but the underlying mechanisms are not *** study was to find out whether systemic inflammation plays an important ***:A total of 103 patients with early-stage HCC under liver resection were enrolled(LLR group,n=53;OLR group,n=50).The expression of 9 inflammatory cytokines in patients at preoperation,postoperative day 1(POD1)and POD7 was quantified by Luminex Multiplex *** relationships of the cytokines and the postoperative outcomes were compared between LLR and ***:Seven of the circulating cytokines were found to be significantly upregulated on POD1 after LLR or OLR compared to their preoperative *** to OLR,the POD1 levels of granulocytemacrophage colony-stimulating factor(GM-CSF),interleukin-6(IL-6),IL-8,and monocyte chemoattractant protein-1(MCP-1)in the LLR group were significantly *** POD1 levels of these cytokines were significantly correlated with longer operative time and higher volume of blood loss during *** levels of these cytokines were positively associated with postoperative liver injury,and the length of hospital ***,a high level of IL-6 at POD1 was a risk factor for HCC recurrence and poor disease-free survival after liver ***:Significantly lower level of GM-CSF,IL-6,IL-8,and MCP-1 after liver resection represented a milder systemic inflammation which might be an important mechanism to offer better short-term and long-term outcomes in LLR over OLR.

关键词： Laparoscopic liver resection Open liver resection Hepatocellular carcinoma Postoperative cytokines Inflammatory responses

Astrocytes. a New Target that Unlocks Brain Disorder Secrets and Drug Discoveries

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中国药理通讯 2013年第3期30卷 8-9页

作者： Albert cheung hoi Yu Neuroscience Research Institute Key Laboratory for Neuroscience (Ministry of Education) Key Laboratory for Neuroscience (National Health and Family Planning Commission) Department of Neurobiology School of Basic Medical Sciences Health Science Center Peking University Beijing 100191 China

Monolithically integrated high-resolution full-color GaN-on-Si micro-LED microdisplay

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Photonics Research 2023年第1期11卷 109-120页

作者： LONGHENG QI XU ZHANG WING cheung CHONG kei MAY LAU Department of Electronic and Computer Engineering The Hong Kong University of Science and TechnologyHong KongChina

Full-color micro-LED displays are being widely developed and regarded as a primary option in current microdisplay technologies to fulfill the urgent demands of metaverse applications in the next *** this paper,a monolithic full-color micro-LED microdisplay with a resolution of 423 pixels per inch is demonstrated through the integration of a blue GaN-on-Si display module and a quantum dots photoresist(QDs-PR)color conversion *** 400×240 active-matrix blue micro-LED display with a dominant wavelength of 440 nm was monolithically fabricated using GaN-on-Si epiwafers and flip-chip bonded on a custom-designed complementary metal-oxide semiconductor backplane.A color conversion module was independently fabricated on a *** substrate by applying red and green QDs-PR arrays and a color filter array through the standard lithography *** the blue GaN-on-Si micro-LED display module and the lithography-based QDs-PR color conversion module,a full-color micro-LED display was achieved with a wide color gamut up to 104%of the standard red,green,and blue and a maximum brightness of over 500 *** influence of blue light leakage resulting from the possible misalignment of flip-chip bonding and crosstalk in the bottom GaN-on-Si display was investigated in which the percentages of efficient pumping light for the blue,green,and red subpixels are around95%,89%,and 92%,*** prototype demonstrates potential scalability and low-cost volume production of high-resolution full-color micro-LED microdisplays soon.

关键词： lithography pumping complementary