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Natural Postoperative Bone Metabolic Changes after Total Knee Arthroplasty Determined by Positron Emission Tomography Scans

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Open Journal of Orthopedics 2018年第12期8卷 443-457页

作者： Masakazu Kanetaka Soichiro Kaneko kei wagatsuma Kenji Ishii Kimiteru Ito Shinya Nakamura Hiroshi Hamaji Yukimasa Yamato Yorito Anamizu Fumiaki Tokimura Tsuyoshi Miyazaki Department of Orthopaedic Surgery Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology Tokyo Japan Research Team for Neuroimaging Research Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology Tokyo Japan Department of Diagnostic Radiology Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology Tokyo Japan Department of Spine Surgery Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology Tokyo Japan

Artificial joint replacement surgery is the orthopedic procedure of choice to relieve pain, correct joint deformities, and help patients resume everyday activities. However, the detailed mechanisms regulating peri-implant bone remodeling at the bone-prosthesis interface remain elusive. To address this gap in knowledge, we evaluated the natural postoperative course of bone metabolism by using [18F] NaF positron emission tomography (PET)/computed tomography in 57 patients (104 joints) who underwent asymptomatic total knee arthroplasty (TKA). First, we measured total tracer uptake around TKA to determine the total bone metabolism (TBM) and used the ischial tuberosity as the reference tissue for normalization of PET images. Second, we calculated the TBM ratio (TBMR) by dividing the TBM by tracer uptake in the reference tissue. A moderate increase in TBMR was observed 4 - 5 days after implantation, and its intensity reached the maximum on the seventh postoperative day. The TBMR showed no differences until 12 weeks, after which it decreased slowly and returned to the basal levels. The new parameter TBMR and the unique pattern of postoperative metabolic changes in the bone around the prosthesis may help set accurate interpretation criteria to diagnose complications such as loosening or infections.

关键词： NaF PET Bone Metabolism Total Knee Arthroplasty Ischial Tuberosity

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日本全国范围内各种显像剂实际使用剂量的调查报告

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中华核医学与分子影像杂志 2017年第7期37卷 445-445页

作者：唐军 Hiroshi Watanabe Kazunari Ishii Makoto Hosono Etsuko Imabayashi Koichiro Abe Masayuki Inubushi Kazuko Ohno Yasuhiro Magata Kinya Ono kei Kikuchi kei wagatsuma Tadashi Takase Kyoko Saito Yasuyuki Takahashi 苏州大学附属第二医院核医学科 Department of Radiological Technology Japan Labour Health and Welfare Organization Yokohama Rosai Hospital Department of Radiology Kindai University Faculty of Medicine

目的医疗照射的最优化在世界范围内都是辐射防护所关心的重要问题之一,国际辐射防护委员会和国际原子能机构推荐建立显像剂使用的剂量参考水平（DRLs）作为控制医疗照射最优化的工具。因此,根据最新调查资料构建DRLs已成为各核医学相关... 详细信息

目的医疗照射的最优化在世界范围内都是辐射防护所关心的重要问题之一,国际辐射防护委员会和国际原子能机构推荐建立显像剂使用的剂量参考水平（DRLs）作为控制医疗照射最优化的工具。因此,根据最新调查资料构建DRLs已成为各核医学相关学会和组织的迫切需要。为构建此DRLs,本研究在全日本范围内调查了核医学成人用显像剂的实际使用剂量。方法调查在2014年11月25日至2015年1月16日间进行,使用调查表方式调查了全日本1249个医疗单位各种显像剂的使用情况,调查结果通过网络反馈收集。结果 516个医疗单位反馈了调查结果,反馈率41%。具体显像包括:99Tcm-MDP和99Tcm-HMDP的骨显像,99Tcm-HM-PAO、99Tcm-ECD和123I-IMP的脑血流显像,99Tcm-Tetrofosmin、99Tcm-MIBI和201Tl-Cl的心肌灌注显像,18F-FDG(自产18F或配送的18F)的肿瘤PET显像。以上显像的第75百分剂量分别是为932、937、763、775、200、831、818、180、235和252 MBq。日本90%以上的医疗单位所使用的显像剂剂量在上述剂量值中位数的50%范围内。很多医疗机构采用包装说明书、文本或指南推荐的剂量,比如740 MBq(99Tcm-MDP和99Tcm-HMDP骨显像)、740 MBq(99Tcm-ECD和99Tcm-HM-PAO脑血流显像)和740 MBq(99Tcm-Tetrofosmin和99Tcm-MIBI心肌灌注显像)等。99Tcm-MDP和99Tcm-HMDP（用于骨显像）、99Tcm-HM-PAO（用于脑血流显像）、99TcmTetrofosmin和99Tcm-MIBI（用于心肌灌注显像）等许多显像剂的使用剂量均在欧盟DRLs内,且大多数在日本使用的显像剂剂量均未超过美国核医学与分子影像学会的标准使用剂量上限。结论本调查结果表明,在日本所使用的各种核医学显像剂的剂量比较集中,各医疗机构均能按照文本和指南要求的剂量越来越严格地使用显像剂。此外,日本显像剂的使用剂量均在欧盟和美国核医学与分子影像学会所规定的使用剂量范围内。

关键词：调查诊断参考水平放射性药物放射性活度剂量最优化

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Heterogeneous Round-Trip Trading and the Emergence of Volatility Clustering in Speculation Game

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Journal of Systems Science & Complexity 2022年第1期35卷 221-244页

作者： KATAHIRA kei CHEN Yu Faculty of Engineering Information and SystemsUniversity of TsukubaTennodai 1-1-1TsukubaIbaraki 305-8573Japan Research Fellow of Japan Society for the Promotion of Science Japan. Graduate School of Frontier Sciences The University of Tokyo5-1-5 KashiwanohaKashiwa-shiChiba-ken 277-8563Japan.

This study is a detailed analysis of Speculation Game,a simple agent-based model of financial markets,in which the round-trip trading and the dynamic wealth evolution with variable trading volumes are *** of herding behavior,the authors find that the heterogeneous holding periods in round-trip trades can contribute to the emergence of volatility *** particular,the spontaneous redistribution of market wealth through repetitions of round-trip trades with non-uniform horizons can widen the wealth disparity and establish the Pareto distribution of the capital *** a result,the intermittent placements of relatively big orders from endogenously emerged rich traders can bring on large fluctuations in price *** data are used to support the scenario derived from the model.

关键词： Financial stylized facts heterogeneity Pareto’s law round-trip trading wealth distribution

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An overview of the contribution of acupuncture to thyroid disorders

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Journal of Integrative Medicine 2018年第6期16卷 375-383页

作者： Fung-kei Cheng Hong Kong China

Thyroid dysfunction, affecting people of all ages, not only damages human growth and energy metabo- lism but is also comorbid with other illnesses such as cardiovascular disease, kidney disease and gastroin- testinal disorders. With the increasing acceptance of alternative and complementary therapies, acupuncture, a traditional Chinese medical practice, has also been employed to address this problem. Analysing 29 clinical projects that were retrieved from 29 major digital databases and include 1757 patients aged 7-79 years from China, Italy, Korea, Macedonia and Russia, this narrative review offers an overview of the efficacy, and evaluated the safe and cost-effective use of acupuncture against hyper- thyroidism, hypothyroidism and thyroid-relevant illnesses. Findings indicated reductions in patient symptoms and improvements in biomarkers where acupuncture was used alone or in combination ther- apy. In addition to showing the role of acupuncture as an alternative and complementary medicine or as an adjunctive therapy for curative and rehabilitative purposes, more well-designed researches are needed to achieve reliable data.

关键词： Acupuncture Alternative and complementary medicine Endocrine system Integrative medicine Traditional Chinese medicine Thyroidism

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Ultrasonic vibrating system design and tool analysis

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中国有色金属学会会刊：英文版 2009年第B9期19卷 225-231页

作者： kei-Lin KUO Department of Vehicle Engineering National Taip ei University of Technology

The applications of ultrasonic vibrations for material removal processes exist predominantly in the area of vertical processing of hard and brittle materials. This is because the power generated by vertical vibrating oscillators generates the greatest direct penetration, in order to conduct material removal on workpieces by grains. However, for milling processes, vertical vibrating power has to be transformed into lateral (horizontal) vibration to produce the required horizontal cutting force. The objective of this study is to make use of ultrasonic lateral transformation theory to optimize processing efficiency, through the use of the finite element method for design and analysis of the milling tool. In addition, changes can be made to the existing vibrating system to generate best performance under consistent conditions, namely, using the same piezoelectric ceramics.

关键词：超声振动系统分析工具设计有限元分析方法超声波振动材料去除垂直振动硬脆材料

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The thermal conductivity of the Earth's core and implications for its thermal and compositional evolution

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National Science Review 2021年第4期8卷 18-20页

作者： Kenji Ohta kei Hirose Department of Earth and Planetary Sciences Tokyo Institute of Technology Earth-Life Science Institute Tokyo Institute of Technology Department of Earth and Planetary Science The University of Tokyo

The thermal conductivity of iron alloys is a key to understanding the mechanism of convection in the Earth’s liquid core and its thermal history. The Earth’s magnetic field is formed by a dynamo action that requires...

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Improved rate-distortion optimized video coding using non-integer bit estimation and multiple Lambda search

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Frontiers of Computer Science 2016年第1期10卷 157-166页

作者： Sio kei IM Mohammad Mahdi GHANDI MPI-QMUL Information Systems Research Centre Macao Polytechnic Institute Macao China Department of Electronic Systems Engineering University of Essex Colchestey CO4 3SQ UK

Many modern video encoders use the Lagrangian rate-distortion optimization （RDO） algorithm for mode deci- sions during the compression procedure. For each encoding stage, this approach involves minimizing a cost, which is a function of rate, distortion and a multiplier called Lambda. This paper proposes to improve the RDO process by applying two modifications. The first modification is to increase the ac- curacy of rate estimation, which is achieved by computing a non-integer number of bits for arithmetic coding of the syntax elements. This leads to a more accurate cost computation and therefore a better mode decision. The second modification is to search and adjust the value of Lambda based on the char- acteristics of each coding stage. For the encoder used, this paper proposes to search multiple values of Lambda for the intra-4x4 mode decision. Moreover, a simple shift in Lambda value is proposed for motion estimation. Each of these modi- fications offers a certain gain in RDO performance, and, when all are combined, an average bit-rate saving of up to 7.0% can be achieved for the H.264/AVC codec while the same concept is applicable to the H.265/HEVC codec as well. The extra added complexity is contained to a certain level, and is also adjustable according to the processing resources available.

关键词： rate distortion optimization Lambda adjust-ment non-integer bit estimation H.264/AVC H265/HEVCvideo coding

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Rotary ultrasonic-assisted milling of brittle materials

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中国有色金属学会会刊：英文版 2012年第S3期22卷 793-800页

作者： KUO kei-lin TSAO Chung-chen Department of Vehicle Engineering National Taipei University of Technology Department of Automation Engineering Tahua Institute of Technology

In order to improve the machining efficiency of ultrasonic milling,the easiest and most effective approach was started with the improvement of tool *** main objective of this research was to utilize rotary ultrasonic machining (RUM's) effectiveness in removing brittle materials to extend the applications of this independent,innovative manufacturing method (self-driving rotary ultrasonic machining),and to experimentally investigate its milling application on brittle *** designed tool was used in the conjunction with previously established RUM machine tools,and glass was selected as workpiece for *** interrelationship between feed rate and depth of cut was *** measuring the surface roughness of workpiece,the overall efficacy of utilizing RUM for milling was evaluated and *** assisted milling results in the reduction of milling resistance,which leads to a greater process rate.

关键词： rotary ultrasonic ultrasonic assisted milling brittle material

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Mass balance of saline lakes considering inflow loads of rivers and groundwater: the case of Lake Issyk-Kul, Central Asia

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Journal of Arid Land 2021年第12期13卷 1260-1273页

作者： kei SAITOH Rysbek SATYLKANOV Kenji OKUBO Beppu Geothermal Research Laboratory Institute for Geothermal SciencesGraduate School of ScienceKyoto UniversityOita 8740903Japan Tien Shan High Mountain Research Center Institute of Water Problem and Hydropower of National Academy of Sciences of Kyrgyz RepublicBishkek 720033Kyrgyzstan Graduate School of Environmental and Life Science Okayama UniversityOkayama 7008530Japan

This study aimed to elucidate the influence of inflow water on the salinity concentration process of a saline lake and the mass balance of Lake Issyk-Kul,a tectonic saltwater lake in *** on the survey results and meteorological data from 2012 to 2015,we analyzed the dissolved chemical composition loads due to water ***,we discussed the relationship between the increase in salinity and water inflow into the *** the water quality analysis data,we used the tank model to estimate the river inflow and analyze the loads by the L-Q *** groundwater loads were then estimated from the average annual increase in salinity of the lake over a period of 30 *** results suggest that Lake Issyk-Kul was temporarily freshened between about AD 1500 and 1800 when an outflowing river existed,and thereafter,it became a closed lake in AD 1800 and continued to remain a saline lake until *** chemical components that cause salinization are supplied from the rivers and groundwater in the catchment area,and when they flow into the lake,Ca^(2+),HCO_(3)−and Mg^(2+)precipitate as CaCO_(3) and MgCO_(3).These compounds were confirmed to have been left on the lakeshore as *** model analysis showed that 1.67 mg/L of Ca^(2+)and Mg^(2+)supplied from rivers and groundwater are precipitated as evaporite and in other forms per *** the other hand,salinity continues to remain in the lake water at a rate of 27.5 mg/L per *** are the main causes of increased salinity in Lake *** Na^(+)and Cl^(-)are considered to be derived from geothermal water,they will continue to flow in regardless of the effects of human ***,as long as these components are accumulated in Lake Issyk-Kul as a closed lake,the salinity will continue to increase in the future.

关键词： groundwater geothermal water mass balance salinity saline lake L-Q curve

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Ultrasonic-assisted vibration tapping using taps with different coatings

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中国有色金属学会会刊：英文版 2012年第S3期22卷 764-768页

作者： Chung-chen TSAO kei-lin KUO Tahua University of Science and Technology National Taipei University of Technology

A machine vision for assessing and inspecting the ratio of thread areas associated with fixed frequency (FF) and limited tracing frequency (LTF) ultrasonic-assisted vibration was presented using differently coated taps after tapping of Ti-6Al-4V *** results indicate that TiAlN Micran taps yield the best tapping quality for different coatings and tapping *** Micran coated taps with LTF make the largest improvement over traditional tapping (TT),with an average increase of 30.2%.

关键词： tapping fixed frequency limited tracing frequency Ti-6Al-4V alloys

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