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Acta Oceanologica Sinica 2023年第6期42卷 16-23页

作者： Zhixin Li Meng Zhang keda liang Jing Wang College of Physics and Optoelectronic Engineering Ocean University of ChinaQingdao 266100China

A series of experiments are designed to propose a new method to study the characteristics of convex mode-2internal solitary waves(ISWs)in optical remote sensing images using a laboratory-based optical remote sensing simulation *** corresponding wave parameters of large-amplitude convex mode-2 ISWs under smooth surfaces are investigated along with the optical remote sensing characteristic *** mode-2 ISWs in the experimentally obtained optical remote sensing image are produced by their overall modulation effect on the water surface,and the extreme points of the gray value of the profile curve of bright-dark stripes appear at the same location as the real optical remote sensing *** present data extend to a larger range than previous studies,and for the characteristics of large amplitude convex mode-2 ISWs,the experimental results show a second-order dependence of wavelength on *** is a close relationship between optical remote sensing characteristic parameters and wave parameters of mode-2 ISWs,in which there is a positive linear relationship between the bright-dark spacing and wavelength and a nonlinear relationship with the amplitude,especially when the amplitude is very large,there is a significant increase in bright-dark spacing.

关键词： mode-2 internal solitary waves optical remote sensing characteristic parameter wave characteristic

Experimental study on the variation of optical remote sensing imaging characteristics of internal solitary waves with wind speed

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Journal of Oceanology and Limnology 2024年第2期42卷 408-420页

作者： Zhe CHANG Lina SUN Tengfei LIU Meng ZHANG keda liang Junmin MENG Jing WANG School of Physics and Optoelectronic Engineering Ocean University of ChinaQingdao 266100China First Institute of Oceanography Ministry of Natural ResourcesQingdao 266061China Technology Innovation Center for Ocean Telemetry Ministry of Natural ResourcesQingdao 266061China

Optical remote sensing has been widely used to study internal solitary waves(ISWs).Wind speed has an important effect on ISW imaging of optical remote *** light and dark bands of ISWs cannot be observed by optical remote sensing when the wind is too *** relationship between the characteristics of ISWs bands in optical remote sensing images and the wind speed is still *** influence of wind speeds on the characteristics of the ISWs bands is investigated based on the physical simulation experiments with the wind speeds of 1.6,3.1,3.5,3.8,and 3.9 m/*** experimental results show that when the wind speed is 3.9 m/s,the ISWs bands cannot be observed in optical remote sensing images with the stratification of h_(1)∶h_(2)=7∶58,ρ_(1)∶ρ_(2)=1∶*** the wind speeds are 3.1,3.5,and 3.8 m/s,which is lower than 3.9 m/s,the ISWs bands can be obtained in the simulated optical remote sensing *** location of the band’s dark and light extremum and the band’s peak-to-peak spacing are almost not affected by wind ***-significant wind speeds can cause a greater gray difference of the light-dark *** provided a scientific basis for further understanding of ISW optical remote sensing imaging.

关键词： internal solitary wave(ISW) optical remote sensing wind speed characteristics of ISWs bands

Experimental Study on the Variation of Optical Imaging Characteristics with Zenith Angle due to Internal Solitary Waves in Sunglint

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Journal of Ocean University of China 2024年第4期23卷 943-952页

作者： LIU Tengfei SUN Lina CHANG Zhe ZHANG Meng liang keda MENG Junmin WANG Jing School of Physics and Optoelectronic Engineering Ocean University of ChinaQingdao 266100China First Institute of Oceanography Ministry of Natural ResourcesQingdao 266061China Technology Innovation Center for Ocean Telemetry Ministry of Natural ResourcesQingdao 266061China

Internal solitary waves(ISWs)change the roughness of the sea surface,thus producing dark and bright bands in optical ***,reasons for changes in imaging characteristics with the solar zenith angle remain *** this paper,the optical imaging pattern of ISWs in sunglint under different zenith angles of the light source is investigated by collecting optical images of ISWs through physical *** experiment involves setting 10 zenith angles of the light source,which are divided into area a the optical images of ISWs in the three areas show dark-bright mode,single bright band,and bright-dark mode,which are consistent with those observed by optical remote *** addition,this study analyzed the percentage of the dark and bright areas of the bands and the change in the relative gray difference and found changes in both areas under different zenith angles of the light *** MODIS and ASAR images display a similar brightness-darkness distance of the same ***,the relationship between the brightness-darkness distance and the characteristic half-width of ISWs is determined in accordance with the eKdV theory and the imaging mechanism of ISWs of the SAR ***,the relationship between them in the experiment is almost consistent with the theoretical result.

关键词： internal solitary waves optical imaging characteristic laboratory simulation zenith angle sunglint

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欧洲投资银行气候投融资发展回顾与经验启示

海外投资与出口信贷 2024年第4期 24-27页

作者：王浩杰梁可达中国中铁国际集团有限公司

近年来,多边开发银行为减缓与适应气候变化募集了大量的绿色资金,有力支持了世界经济和社会稳健、可持续发展。欧投行是其中典型代表。自20世纪90年代起,欧投行逐步将气候金融纳入优先发展方向,在国际金融市场上率先发行绿色债券,推动... 详细信息

近年来,多边开发银行为减缓与适应气候变化募集了大量的绿色资金,有力支持了世界经济和社会稳健、可持续发展。欧投行是其中典型代表。自20世纪90年代起,欧投行逐步将气候金融纳入优先发展方向,在国际金融市场上率先发行绿色债券,推动碳排放交易系统,积极与他方寻求合作广开资金渠道,并在发展过程中不断创新,努力转型为全球首家气候银行。欧投行气候投融资的成功经验值得其他多边开发银行及政策性金融机构借鉴。

关键词：气候变化投融资绿色开放合作

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南海东沙岛北部第二模态内孤立波特性研究

中国海洋大学学报（自然科学版） 2021年第11期51卷 16-21页

作者：崔海吉李志鑫张猛黄松松梁可达王晶中国海洋大学信息科学与工程学院山东青岛266100

高分一号是中国自主发射的光学遥感卫星,空间分辨率达到2、8和16 m,因此可以为尺度较小的第二模态内孤立波研究提供强有力的数据支撑。本文基于2014—2020年共7年高分一号光学遥感图像研究了南海东沙岛北部第二模态内孤立波特性,研究结... 详细信息

高分一号是中国自主发射的光学遥感卫星,空间分辨率达到2、8和16 m,因此可以为尺度较小的第二模态内孤立波研究提供强有力的数据支撑。本文基于2014—2020年共7年高分一号光学遥感图像研究了南海东沙岛北部第二模态内孤立波特性,研究结果表明:在海水层结不变,海域第二模态内孤立波的光学遥感图像条纹亮暗次序与第一模态内孤立波的相反;第二模态内孤立波的波峰线远短于第一模态内孤立波的波峰线;南海东沙岛北部第二模态内孤立波在夏季被光学遥感观测到的概率最大;绝大部分第二模态内孤立波尾随在第一模态内孤立波之后,可能是第一模态内孤立波与地形凸起相互作用而产生了第二模态内孤立波。这一研究结果对于进一步研究全球海域第二模态内孤立波的特性奠定了良好基础。

关键词：高分一号卫星光学遥感图像第二模态内孤立波东沙岛北部

Experimental Study on the Variation of Optical Imaging Characteristics with Zenith Angle due to Internal Solitary Waves in Sunglint

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The dopaminergic system and Alzheimer's disease

中国海洋大学学报（自然科学英文版） 2024年第4期 943页

作者： LIU Tengfei SUN Lina CHANG Zhe ZHANG Meng liang keda MENG Junmin WANG Jing

来源：博看期刊评论

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Neural Regeneration Research 2025年第9期20卷 2495-2512页

作者： Yuhan Zhang Yuan liang Yixue Gu International Medical College Chongqing Medical UniversityChongqingChina College of Pharmacy Chongqing Medical UniversityChongqingChina Department of Neurology The First Affiliated Hospital of Chongqing Medical UniversityChongqing Key Laboratory of NeurologyChongqingChina

Alzheimer's disease is a common neurodegenerative disorder in older *** its prevalence,its pathogenesis remains unclea *** addition to the most widely accepted causes,which in clude excessive amyloid-beta aggregation,tau hyperphosphorylation,and deficiency of the neurotransmitter acetylcholine,numerous studies have shown that the dopaminergic system is also closely associated with the occurrence and development of this *** is a crucial catecholaminergic neurotransmitter in the human ***-associated treatments,such as drugs that target dopamine receptor D and dopamine analogs,can improve cognitive function and alleviate psychiatric symptoms as well as ameliorate other clinical *** r,therapeutics targeting the dopaminergic system are associated with various adverse reactions,such as addiction and exacerbation of cognitive *** review summarizes the role of the dopaminergic system in the pathology of Alzheimer's disease,focusing on currently available dopamine-based therapies for this disorder and the common side effects associated with dopamine-related *** aim of this review is to provide insights into the potential connections between the dopaminergic system and Alzheimer's disease,thus helping to clarify the mechanisms underlying the condition and exploring more effective therapeutic options.

关键词： adverse drug reaction Alzheimer's disease catecholamine dopamine receptor dopamine receptor heterodimers dopaminergic system neurodegenerative disease neurotransmitter signaling pathways traditional Chinese medicine treatment

Epigenetic regulation of the inflammatory response in stroke

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Neural Regeneration Research 2025年第11期20卷 3045-3062页

作者： Jingyi liang Fei Yang Zixiao Li Qian Li School of Basic Medical Sciences Capital Medical UniversityBeijingChina Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina Laboratory for Clinical Medicine Beijing Key Laboratory of Neural Regeneration and RepairCapital Medical UniversityBeijingChina Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina China National Clinical Research Center for Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina National Center for Healthcare Quality Management in Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Chinese Institute for Brain Research BeijingChina Research Unit of Artificial Intelligence in Cerebrovascular Disease Chinese Academy of Medical SciencesBeijingChina Beijing Engineering Research Center of Digital Healthcare for Neurological Diseases BeijingChina Department of Biochemistry and Molecular Biology School of Basic Medical SciencesCapital Medical UniversityBeijingChina Beijing Key Laboratory of Cancer Invasion and Metastasis Research Capital Medical UniversityBeijingChina

Stroke is classified as ischemic or hemorrhagic,and there are few effective treatments for either *** mechanisms play a critical role in secondary brain injury following a stroke,which manifests as cytokine release,blood–brain barrier disruption,neuronal cell death,and ultimately behavioral *** the inflammatory response has been shown to mitigate this cascade of events in experimental stroke ***,in clinical trials of anti-inflammatory agents,longterm immunosuppression has not demonstrated significant clinical benefits for *** may be attributable to the dichotomous roles of inflammation in both tissue injury and repair,as well as the complex pathophysiologic inflammatory processes in *** acute harmful inflammatory responses or inducing a phenotypic shift from a pro-inflammatory to an anti-inflammatory state at specific time points after a stroke are alternative and promising therapeutic *** agents that can modulate inflammation requires a detailed understanding of the inflammatory processes of ***,epigenetic reprogramming plays a crucial role in modulating post-stroke inflammation and can potentially be exploited for stroke *** this review,we summarize current findings on the epigenetic regulation of the inflammatory response in stroke,focusing on key signaling pathways including nuclear factor-kappa B,Janus kinase/signal transducer and activator of transcription,and mitogen-activated protein kinase as well as inflammasome *** also discuss promising molecular targets for stroke *** evidence to date indicates that therapeutic targeting of the epigenetic regulation of inflammation can shift the balance from inflammation-induced tissue injury to repair following stroke,leading to improved post-stroke outcomes.

关键词： DNA methylation histone modification intracerebral hemorrhage ischemic stroke neuroinflammation neuroprotection non-coding RNA RNA methylation subarachnoid hemorrhage treatment

Magneto‑Dielectric Synergy and Multiscale Hierarchical Structure Design Enable Flexible Multipurpose Microwave Absorption and Infrared Stealth Compatibility

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Nano-Micro Letters 2025年第2期17卷 401-416页

作者： Chen Li Leilei liang Baoshan Zhang Yi Yang Guangbin Ji School of Electronic Science and Engineering Nanjing UniversityNanjing 210093People’s Republic of China College of Materials Science and Technology Nanjing University of Aeronautics and AstronauticsNanjing 210016People’s Republic of China

Developing advanced stealth devices to cope with radar-infrared(IR)fusion detection and diverse application scenarios is increasingly demanded,which faces significant challenges due to conflicting microwave and IR cloaking mechanisms and functional integration ***,we propose a multiscale hierarchical structure design,integrating wrinkled MXene IR shielding layer and flexible Fe_(3)O_(4)@C/PDMS microwave absorption *** top wrinkled MXene layer induces the intensive diffuse reflection effect,shielding IR radiation signals while allowing microwave to pass ***,the permeable microwaves are assimilated into the bottom Fe_(3)O_(4)@C/PDMS layer via strong magneto-electric *** theoretical and experimental optimization,the assembled stealth devices realize a near-perfect stealth capability in both X-band(8–12 GHz)and long-wave infrared(8–14μm)wavelength ***,it delivers a radar cross-section reduction of−20 dB m^(2),a large apparent temperature modulation range(ΔT=70℃),and a low average IR emissivity of ***,the optimal device demonstrates exceptional curved surface conformability,self-cleaning capability(contact angle≈129°),and abrasion resistance(recovery time≈5 s).This design strategy promotes the development of multispectral stealth technology and reinforces its applicability and durability in complex and hostile environments.

关键词： Microwave absorption Radar-infrared compatible stealth Wrinkled MXene Magneto-dielectric synergy Multifunction

Potassium and calcium channels in different nerve cells act as therapeutic targets in neurological disorders

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Neural Regeneration Research 2025年第5期20卷 1258-1276页

作者： Qing Qiu Mengting Yang Danfeng Gong Haiying liang Tingting Chen Department of Pharmacology School of PharmacyNantong UniversityNantongJiangsu ProvinceChina Jiangsu Province Key Laboratory of Inflammation and Molecular Drug Target NantongJiangsu ProvinceChina Department of Pharmacy Longyan First Affiliated Hospital of Fujian Medical UniversityLongyanFujian ProvinceChina

The central nervous system, information integration center of the body, is mainly composed of neurons and glial cells. The neuron is one of the most basic and important structural and functional units of the central nervous system, with sensory stimulation and excitation conduction functions. Astrocytes and microglia belong to the glial cell family, which is the main source of cytokines and represents the main defense system of the central nervous system. Nerve cells undergo neurotransmission or gliotransmission, which regulates neuronal activity via the ion channels, receptors, or transporters expressed on nerve cell membranes. Ion channels, composed of large transmembrane proteins, play crucial roles in maintaining nerve cell homeostasis. These channels are also important for control of the membrane potential and in the secretion of neurotransmitters. A variety of cellular functions and life activities, including functional regulation of the central nervous system, the generation and conduction of nerve excitation, the occurrence of receptor potential, heart pulsation, smooth muscle peristalsis, skeletal muscle contraction, and hormone secretion, are closely related to ion channels associated with passive transmembrane transport. Two types of ion channels in the central nervous system, potassium channels and calcium channels, are closely related to various neurological disorders, including Alzheimer's disease, Parkinson's disease, and epilepsy. Accordingly, various drugs that can affect these ion channels have been explored deeply to provide new directions for the treatment of these neurological disorders. In this review, we focus on the functions of potassium and calcium ion channels in different nerve cells and their involvement in neurological disorders such as Parkinson's disease, Alzheimer's disease, depression, epilepsy, autism, and rare disorders. We also describe several clinical drugs that target potassium or calcium channels in nerve cells and could be u

关键词： astrocytes calcium channels central nervous system extracellular ion concentration microglia neurological disorders neurons potassium channels