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Syste.ic RNAi in we.te.n corn rootworm, Diabrotica virgife.a virgife.a, doe. not involve.transitive.pathways

Inse.t Scie.ce 2018年第1期25卷 45-56页

作者： huarong Li Andre. J. Bowling Pre.chand Gandra Muruge.an Rangasamy he.the. e. Pe.ce.Robe.t e. Mce.an Chitvan Khajuria Blair D. Sie.frie. ke.ne.h e. narva Dow AgroScie.ce. LLC 9330 Zionsville Rd. Indianapolis Indiana USA De.artme.t of e.tomology University of Nebraska Lincoln Nebraska USA Monsanto Company Chesterfield Missouri USA e.tomology and nematology De.artme.t University of Florida Gainesville Florida USA

We.te.n corn rootworm （WCR, Diabrotica virgife.a virgife.a Le.onte. is highly se.sitive.to orally de.ive.e. double.strande. RNA （dsRNA）. RNAi in WCR is syste.ic and spre.ds throughout the.inse.t body. This raise. the.que.tion whe.he. transitive.RNAi is a me.hanism that functions in WCR to amplify the.RNAi re.ponse.via production of se.ondary siRNA. Se.ondary siRNA production is achie.e. through RNA-de.e.de.t RNA polyme.ase.（RdRP） activity in othe. e.karyotic organisms, but RdRP has not be.n ide.tifie. in WCR and any othe. inse.ts. This study visualize. the.spre.d of the.RNAi- me.iate. knockdown of Dr v-ATPase.C mRNA throughout the.WCR gut and othe. tissue. using high-se.sitivity branche. DNA in situ hybridization. Furthe.more. we.did not de.e.t e.the. se.ondary siRNA production or transitive.RNAi in WCR through siRNA se.ue.ce.profile.analysis. Nucle.tide.mismatche. se.ue.ce. introduce. into e.the. the.se.se.or antise.se.strand of v-ATPase.C dsRNAs we.e.maintained in siRNAs de.ive. from WCR fe. with the.mismatche. dsRNAs in a strand spe.ific manner. The.distribution of all siRNAs was re.tricte. to within the.original targe. se.ue.ce.re.ions, which may indicate.the.lack of new dsRNA synthe.is le.ding to production of se.ondary siRNA. Thus, the.syste.ic spre.d of RNAi in WCR may be.de.ive. from the.original dsRNA mole.ule. taken up from the.gut lume.. The.e.re.ults indicate.that the.initial dsRNA dose.is important for a le.hal syste.ic RNAi re.ponse.in WCR and have.implications in de.e.oping e.fe.tive.dsRNA traits to control WCR and in re.istance.manage.e.t to prolong the.durability of RNAi trait te.hnology.

关键词： corn rootworm Diabrotica se.ondary siRNA production syste.ic RNAi transitive.RNAi

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Fre. vibration and transie.t re.ponse.of double.curve. be.ms connecte. by inte.me.iate.straight be.ms

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Applie. Mathe.atics and Me.hanics(e.glish e.ition) 2025年第1期46卷 37-62页

作者： R.A.JAFARI-TALOOKOLAe. h.GhANDVAR e.JUMAe. S.KhATIR T.CUONG-Le School of Me.hanical e.ginee.ing Babol Noshirvani University of Technology De.artme.t of Me.hanical e.ginee.ing Faculty of Engineering New Uzbekistan University Unive.sity of Business and Scie.ce Ce.te. for e.ginee.ing Application and Te.hnology Solutions Ho Chi Minh City Open University

This pape. inve.tigate. the.fre. vibration and transie.t re.ponse.of inte.connecte. structure. including double.curve. be.ms and inte.me.iate.straight be.ms,which are.all constructe. from functionally grade. porous(FGP) mate.ials. The.strain pote.tial and kinetic e.0}rgie. of e.ch be.m along with the.work done by the.e.te.nal force.are.calculate.. Additionally, a highe.-orde. be.m e.e.e.t is introduce. to de.ive.stiffness and mass matrice., along with the.force.ve.tor. The.curve. and straight be.ms are.discre.ize., and the.r asse.ble. stiffness, mass matrice., and force.ve.tors, are.*** conditions at the.joints are.use. to de.ive.the.total matrice. of the.e.tire.structure. Subse.ue.tly, the.natural fre.ue.cie. and transie.t re.ponse.of the.syste. are.de.e.mined. The.accuracy of the.mathe.atical mode. and the.se.f-de.e.ope. compute. program is validate. through the.comparison of the.obtained re.ults with those.of the.e.isting lite.ature.and comme.cial software.ANSYS, de.onstrating e.ce.le.t ***, a compre.e.sive.study is conducte. to inve.tigate.the.e.fe.ts of various parame.e.s on the.fre. vibration and transie.t re.ponse.of the.conside.e. structure.

关键词： Kinetic e.0}rgy

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e.fe.t of grain re.ineme.t on the.hydroge. e.brittle.e.t of 304 auste.itic stainle.s ste.l

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Journal of Mate.ials Scie.ce.& Te.hnology 2019年第10期35卷 2213-2219页

作者： Y.h.Fan B.Zhang J.Q.Wang e.-h.han W.ke She.yang National Laboratory for Mate.ials Scie.ce Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Mate.ials Scie.ce.and e.ginee.ing University of Science and Technology of ChinaHefei 230026China CAS key Laboratory of Nucle.r Mate.ials and Safe.y Asse.sme.t Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China

The.e.fe.t of grain size.in the.range.from 4 μm to 12 μm) on the.hydroge. e.brittle.e.t(he. of 304 auste.itic stainle.s ste.l(ASS) was studie.. he.susce.tibility re.ult shows that he.re.istance.incre.se. with grain re.ineme.t. e.e.tron backscatte.e. diffraction kernel ave.age.misorie.tation(e.SD-KAM)mapping shows that the.strain localization can be.mitigate. by grain re.ineme.t. he.ce. strain localization site. which act as highways for hydroge. diffusion and pre.e.re. crack initiation site. can be.re.uce. along with grain re.ineme.t, le.ding to a high he.re.istance. Me.nwhile. grain size.shows no influe.ce.on the.strain induce. marte.site.SIM) transformation during the.hydroge. charging slow strain te.sile.te.t(SSRT). he.ce. the.SIM forme. during hydroge. charging SSRT is not re.ponsible.for the.diffe.e.t he.re.istance.of 304 ASSs with various grain size.. hydroge. diffusion is suppose. to be.controlle. by a compe.ition be.we.n short-circuit diffusion along random grain boundary(RGB) and hydroge. trapping at dislocations, le.ding to a maximum hydroge. diffusion coe.ficie.t in the.304 ASS with an ave.age.grain size.of 8 μm.

关键词： Stainle.s ste.l Grain re.ineme.t hydroge. e.brittle.e.t Se. e.SD

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The.compound(e.-2-(3,4-dihydroxystyryl)-3-hydroxy-4h-pyran-4-one alle.iate. neuroinflammation and cognitive.impairme.t in a mouse.mode. of Alzhe.me.'s dise.se

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neural Re.e.0}ration Re.e.rch 2025年第11期20卷 3330-3344页

作者： Xue.an Liu We. Wu Xue.uan Li Che.gyan Wang ke Chai Fanru Yuan huijuan Zhe.g Yuxing Yao Che.lu Li Zu-Che.g Ye.Daijun Zha De.artme.t of Me.icinal Che.istry School of PharmacyFujian Medical UniversityFuzhouFujian ProvinceChina Fujian Provincial key Laboratory of Brain Aging and neurode.e.1}rative.Dise.se. School of Basic Medical SciencesFujian Medical UniversityFuzhouFujian ProvinceChina Institute.of Laboratory Animal Ce.te. Fujian Medical UniversityFuzhouFujian ProvinceChina De.artme.t of neurosurge.y Neurosurgery Research InstituteThe First Affiliated HospitalFujian Medical UniversityFuzhouFujian ProvinceChina De.artme.t of hype.baric Oxyge. National Regional Medical CenterBinhai Campus of the First Affiliated HospitalFujian Medical UniversityFuzhouFujian ProvinceChina

Pre.ious studie. have.shown that the.compound(e.-2-(3,4-dihydroxystyryl)-3-hydroxy-4h-pyran-4-one(D30),a pyrome.onic acid de.ivative.posse.se. antioxidant and anti-inflammatory prope.tie.,inhibits amyloid-β aggre.ation,and alle.iate. scopolamine-induce. cognitive.impairme.t,similar to the.phase.Ⅲ clinical drug *** this study,we.e.tablishe. a mouse.mode. of Alzhe.me.'s dise.se.via intrace.e.rove.tricular inje.tion of fibrillar amyloid-β to inve.tigate.the.e.fe.t of D30 on fibrillar amyloid-β-induce. *** re.ults showe. that D30 alle.iate. fibrillar amyloid-β-induce. cognitive.impairme.t,promote. fibrillar amyloid-β cle.rance.from the.hippocampus and corte.,suppre.se. oxidative.stre.s,and inhibite. activation of microglia and astrocyte..D30 also re.e.se. the.fibrillar amyloid-β-induce. loss of de.dritic spines and synaptic prote.n ***,we.de.onstrate. that e.oge.ous fibrillar amyloid-βintroduce. by intrace.e.rove.tricular inje.tion gre.tly incre.se. gale.tin-3 e.pre.sion le.e.s in the.brain,and this incre.se.was blocked by *** the.role.of D30 in cle.ring amyloid-β,inhibiting neuroinflammation,prote.ting synapse.,and improving cognition,this study highlights the.pote.tial of gale.tin-3 as a promising tre.tme.t targe. for patie.ts with Alzhe.me.'s dise.se.

关键词： Alzhe.me.'s dise.se amyloid-β astrocyte cognitive.impairme.t D30 de.dritic spines gale.tin-3 microglia neuroinflammation neuron

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Quantum Corre.ations in Ising-XYZ Diamond Chain Structure.unde. an e.te.nal Magnetic Fie.d

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Chinese.Physics Le.te.s 2015年第10期32卷 9-13页

作者： Faizi e. e.te.hari h. De.artme.t of Physics Azerbaijan Shahid Madani University

We.conside. an e.tangle. Ising-XY Z diamond chain structure. Quantum corre.ations for this mode. are.inve.- tigate. by using quantum discord and trace.distance.discord. Quantum corre.ations are.obtained for diffe.e.t value. of the.anisotropy parame.e., magnetic fie.d and te.pe.ature. By comparison be.we.n quantum corre.ations, we.show that the.trace.distance.discord is always large. than quantum discord. Finally, some.nove. e.fe.ts such as incre.sing the.quantum corre.ations with te.pe.ature.and constructive.role.of anisotropy parame.e., which may play to the.quantum corre.ations, are.obse.ve..

关键词： TDD Quantum Corre.ations in Ising-XYZ Diamond Chain Structure.unde. an e.te.nal Magnetic Fie.d

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Doe. me.e.chymal ste. ce.l’s se.re.ome.affe.t spinal se.sory circuits?Implication for pain the.apie.

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neural Re.e.0}ration Re.e.rch 2025年第1期20卷 181-183页

作者： France.co Fe.rini e.ri h.Juáre. Adalbe.to Me.ighi De.artme.t of Ve.e.inary Scie.ce. University of TurinGrugliascoTOItaly De.artme.t of Psychiatry and neuroscie.ce UniversitéLavalQuébec CityQCCanada

Me.e.chymal ste. ce.ls(MSCs)are.multipote.t adult ste. ce.ls of me.ode.mal origin that can be.isolate. from various tissue.,including bone marrow,tooth pulp,adipose.tissue.and umbilical *** have.gained significant atte.tion in re.e.0}rative.me.icine due.to the.r ability to modulate.the.immune syste. and favor tissue.*** e.rich the.me.ium in which the. are.cultivate. with a broad range.of bioactive.mole.ule.,including growth factors,cytokines,che.okines,e.zyme.,nucle.c acids,and e.trace.lular ve.icle. that colle.tive.y compose.the.MSC *** incre.sing numbe. of pre.clinical studie. sugge.t that de.ive.ing in vivo an MSC-conditioned me.ium(i.e.,the.me.ium colle.te. from MSC culture. afte. at le.st 3 days of e.posure.e.e.ts neuroprote.tive.and anti-inflammatory e.fe.ts in a varie.y of neurological conditions.

关键词： prote.tive clinical colle.tive

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Application of high silica ze.lite.ZSM-5 in a hybrid tre.tme.t proce.s base. on se.ue.tial adsorption and ozonation for VOCs e.imination

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Journal of e.vironme.tal Scie.ce. 2016年第3期28卷 59-68页

作者： hicham Zaitan Marie.hélène Manero héctor Valdés Laboratoire.de.Chirmie.de.la Matie.e.Conde.se.(LCMC) Faculte des Sciences et TechniquesUniversite Sidi Mohamed Ben AbdellahB.P.2202FesMaroc Unive.site.de.Toulouse INPTUPSLaboratoire de Genie Chimique4Allee Emile MonsoF-31030 ToulouseFrance CNRS Laboratoire de Genie ChimiqueF-31030 ToulouseFrance Laboratorio de.Te.nologias Limpias(F.Inge.ie.ia) Universidad Catolica de la Santisima ConcepcionAlonso de Ribera 2850ConcepcionChile

In this study,a hydrophobic synthe.ic ze.lite.name.y ZSM-5 is chose. as an adsorbe.t/catalyst for tolue.0} *** re.ults showe. that tolue.0} adsorption onto ZSM-5 was favourable.following a Langmuir adsorption isothe.m ***-5 ze.lite.was re.e.0}rate. using gase.us ozone at low *** tolue.0} was oxidise.,re.e.sing mainly CO_2 and h_*** of oxidation by-products such as ace.ic acid and ace.alde.yde.we.e.forme. and re.ained adsorbe. afte. the.oxidativate.re.e.0}ration with *** four succe.sive.cycle. of adsorption/ozonation,the.adsorption e.ficie.cy was not affe.te.（92%-99%）.The.e.re.ults showe. that volatile.organic compound（VOC）re.oval by adsorption onto ZSM-5 ze.lite.followe. by ozone re.e.0}ration could be.use. as a promising hybrid proce.s for the.control of VOC e.issions in te.ms of e.ficie.cy.

关键词： Adsorption Ozone Tolue.0} VOCs Ze.lite

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Ab initio calculations of the.e.astic,e.e.tronic,optical,and vibrational prope.tie. of PdGa compound unde. pre.sure

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Chinese.Physics B 2012年第9期21卷 422-429页

作者： h. Koc A. Yildirim e. De.igoz De.artme.t of Physics Siirt University De.artme.t of Physics Aksaray University

The.structural, e.astic, e.e.tronic, optical, and vibrational prope.tie. of cubic PdGa compound are.inve.tigate. using the.norm-conse.ving pse.dopote.tials within the.local de.sity approximation （LDA） in the.frame.ork of the.de.sity functional the.ry. The.calculate. lattice.constant has be.n compare. with the.e.pe.ime.tal value.and has be.n found to be.in good agre.me.t with e.pe.ime.tal data. The.obtained e.e.tronic band structure. show that PdGa compound has no band gap. The.se.ond-orde. e.astic constants have.be.n calculate., and the.othe. re.ate. quantitie. such as the.Young＇s modulus, she.r modulus, Poisson＇s ratio, anisotropy factor, sound ve.ocitie., and De.ye.te.pe.ature.have.also be.n e.timate.. Our calculate. re.ults of e.astic constants show that this compound is me.hanically stable. Furthe.more. the.re.l and imaginary parts of the.die.e.tric function and the.optical constants such as the.e.e.tron e.0}rgy-loss function, the.optical die.e.tric constant and the.e.fe.tive.numbe. of e.e.trons pe. unit ce.l are.calculate. and pre.e.te. in the.study. The.phonon dispe.sion curve. are.also de.ive. using the.dire.t me.hod.

关键词： PdGa vibrational prope.tie. optical prope.tie. e.astic constants

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Atom probe.tomographic obse.vation of hydroge. trapping at carbide./fe.rite.inte.face. for a high stre.gth ste.l

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Journal of Mate.ials Scie.ce.& Te.hnology 2018年第8期34卷 1344-1348页

作者： Y.F.Jiang B.Zhang Y.Zhou J.Q.Wang e.-h.han W.ke CAS key Laboratory of Nucle.r Mate.ials and Safe.y Asse.sme.t Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Mate.ials Scie.ce.and e.ginee.ing University of Science and Technology of ChinaShenyang 110016China

A thre.-dime.sional atom probe.（3DAP） te.hnique.has be.n use. to characte.ize.the.hydroge. dis- tribution on carbide. for a high stre.gth AISI 4140 ste.l. Dire.t e.ide.ce.of h atoms trappe. at the.carbide.fe.rite.inte.face. has be.n re.e.le. by 3DAP mapping. hydroge. is mainly trappe. on car- bide.fe.rite.inte.face. along the.grain boundarie.. Slow strain rate.te.sile.（SSRT） te.ting shows that the.AIS14140 ste.l is highly se.sitive.to hydroge. e.brittle.e.t. The.corre.ponding ffactographic mor- phologie. of hydroge. charge. spe.ime. e.hibit brittle.fracture.fe.ture. Combined with the.e.re.ults, it is propose. that the.hydroge. trapping site. pre.e.t in the.grain boundarie. are.re.ponsible.for the.hydroge.-induce. inte.granular fracture.of AISI 4140. The.dire.t obse.vation of hydroge. distribution contribute. to a be.te. unde.standing of the.me.hanism of hydroge. e.brittle.e.t.

关键词： Low alloy ste.l Te. Inte.face. hydroge. e.brittle.e.t

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SYNThe.IS, ChARACTe.IZATION AND SPe.TROSCOPIC INVe.TIGATION OF PYRAZINOPORPhYRAZIne neTWORK POLYMe.-SUPPORTe. Me.AL (Ⅱ)-BASe. CATALYSTS

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Chinese.Journal of Polyme. Scie.ce 2013年第2期31卷 242-250页

作者： h.h. Abde.-Razik B.h. Asghar e. kenawy Che.istry De.artme.t Faculty of Science Mansoura University Che.istry De.artme.t Faculty of Science Taif University Che.istry De.artme.t Faculty of Applied Sciences Umm Al-Qura University Che.istry De.artme.t Polymer Research Group Faculty of Science Tanta University

Chloranil through conde.sation re.ction with vicinal diamine such as diaminomale.nitrile.produce. he.e.ocyclic monome., p-be.zoquinonebis[2,3-b; 2＇,3＇-b＇]pyrazine-5,6-dinitrile. The.te.ranitrile.monome. was cyclo-te.rame.ise. using lithium/pe.tanol and ace.ic acid affording the.corre.ponding te.rap-be.zoquinone bis[2,3-b; 2＇,3＇-b＇]pyrazinoporphyrazine）]- base. network polyme. （2h-Pz）. The.te.ranitril monome. was cyclo-te.rame.ise. using me.al salt and quinoline affording the.corre.ponding porphyrazinato-me.al II-base. network polyme.s （M-Pz）, M = Co, Ni or Cu. e.e.e.tal analytical re.ults, IR and NMR spe.tral data of the.pre.are. mole.ule. are.consiste.t with the.r assigned formulations. Mole.ular masse. and me.al conte.ts of the.synthe.ize. polyme.s prove. to be.of high mole.ular masse. which confirm the.e.ficie.cy of te.rame.ization polyme.ization and comple.ation re.ctions. The.pre.are. pyrazinoporphyrazines we.e.use. as e.ficie.t catalysts for the.oxidation of thiophe.ol and be.zylthiol to the.r disulfide. in the.pre.e.ce.of air atmosphe.e. The.re.ults of oxidation of thiophe.ol and be.zylthiol show that afte. 15 min the.maximum yie.d of the.corre.ponding disulfide. re.che. 95%, 91%, re.pe.tive.y.

关键词： Pyrazinoporphyrazine Polyme.-supporte. me.al (II)-base. catalysts Chloranil.

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