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VKFQ:A Verifiable keyword Frequency Query Framework with Local Differential Privacy in Blockchain

Computers, Materials & Continua 2024年第3期78卷 4205-4223页

作者： Youlin ji Bo Yin ke Gu School of Computer and Communication Engineering Changsha University of Science and TechnologyChangsha410114China

With its untameable and traceable properties,blockchain technology has been widely used in the field of data *** to preserve individual privacy while enabling efficient data queries is one of the primary issues with secure data *** this paper,we study verifiable keyword frequency(KF)queries with local differential privacy in *** the numerical and the keyword attributes are present in data objects;the latter are sensitive and require privacy ***,prior studies in blockchain have the problem of trilemma in privacy protection and are unable to handle KF *** propose an efficient framework that protects data owners’privacy on keyword attributes while enabling quick and verifiable query processing for KF *** framework computes an estimate of a keyword’s frequency and is efficient in query time and verification object(VO)size.A utility-optimized local differential privacy technique is used for privacy *** data owner adds noise locally into data based on local differential privacy so that the attacker cannot infer the owner of the keywords while keeping the difference in the probability distribution of the KF within the privacy *** propose the VB-cm tree as the authenticated data structure(ADS).The VB-cm tree combines the Verkle tree and the Count-Min sketch(CM-sketch)to lower the VO size and query *** VB-cm tree uses the vector commitment to verify the query *** fixed-size CM-sketch,which summarizes the frequency of multiple keywords,is used to estimate the KF via hashing *** conduct an extensive evaluation of the proposed *** experimental results show that compared to theMerkle B+tree,the query time is reduced by 52.38%,and the VO size is reduced by more than one order of magnitude.

关键词： Security data sharing blockchain data query privacy protection

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Biogenesis of Rab14-positive Endosome Buds at Golgi-endosome Contacts by the RhoBTB3-SHIP164-Vps26B Complex

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当代医学科学（英文） 2024年第4期44卷 864-866页

作者： jing-ru WANG Jun-yao ZHANG Wei-ke.ji Department of Biochemistry and Molecular Biology School of Basic MedicineTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Biochemistry and Molecular Biology School of Basic MedicineTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Cell Architecture Research Center Huazhong University of Science and TechnologyWuhan 430030China State key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Huazhong University of Science and TechnologyWuhan 430030China Shenzhen Bay Laboratory Shenzhen 518132China

As one of the basic processes of cellular activity,endocytosis sorting determines the fate of many proteins on the endosomal membranes,thus affecting a variety of important cellular processes,such as nutrient uptake,cell signal transduction,intracellular ion homeostasis,*** dysregulation is closely related to various neurological diseases,metabolic disease,and immune disorders[1].Early endosomes(EEs)are crucial in cargo sorting within vesicular trafficking,cargos destined for the plasma membrane or the Golgi are first sorted into the specific membrane structure of the EE-EE buds,and then separated from the EE by membrane fission,and further returned to the plasma membrane or Golgi through a recycling *** that are destined for degradation remain in EE,and as the endosome matures,they are ultimately degraded in the ***,the EE buds play a key role in cargo sorting[2].Currently,the molecular mechanism of EE bud biogenesis is still not fully understood,and the molecular mechanism of membrane lipid regulation during budding is still unknown.

关键词： PHASE-SEPARATION PROTEIN VPS13

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Physical layer security of FSO communication system based on G-G correlation channel

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Optoelectronics Letters 2024年第11期20卷 658-662页

作者： ZHONG Ruijing ji jianhua WANG Zhenhong WANG ke SONG Yufeng College of Electronics and Information Engineering Shenzhen University

In this paper, the eavesdropping model based on eavesdroppers near legitimate users, and the effect of atmospheric channel correlation on the physical layer security(PLS) of the free-space optical(FSO) link are analyzed.

关键词： A

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Historical biogeography and evolutionary diversification of Lilium(Liliaceae): New insights from plastome phylogenomics

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Plant Diversity 2024年第2期46卷 219-228页

作者： Nian Zhou ke Miao Changkun Liu Linbo jia jinjin Hu Yongjiang Huang Yunheng ji CAS key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunmingYunnan 650201China University of Chinese Academy of Sciences Beijing 100049China key Laboratory of Bio-Resources and Eco-Environment of Ministry of Education College of Life SciencesSichuan UniversityChengduSichuan 610065China Yunnan key Laboratory for Integrative Conservation of Plant Species with Extremely Small Population Kunming Institute of BotanyChinese Academy of SciencesKunmingYunnan 650201China

Here, we infer the historical biogeography and evolutionary diversification of the genus Lilium. For this purpose, we used the complete plastomes of 64 currently accepted species in the genus Lilium(14plastomes were newly sequenced) to recover the phylogenetic backbone of the genus and a timecalibrated phylogenetic framework to estimate biogeographical history scenarios and evolutionary diversification rates of Lilium. Our results suggest that ancient climatic changes and geological tectonic activities jointly shaped the distribution range and drove evolutionary radiation of Lilium, including the Middle Miocene Climate Optimum(MMCO), the late Miocene global cooling, as well as the successive uplift of the Qinghai-Tibet Plateau(QTP) and the strengthening of the monsoon climate in East Asia during the late Miocene and the Pliocene. This case study suggests that the unique geological and climatic events in the Neogene of East Asia, in particular the uplift of QTP and the enhancement of monsoonal climate, may have played an essential role in formation of uneven distribution of plant diversity in the Northern Hemisphere.

关键词： Asian monsoon Climatic changes Distribution range Evolutionary complexity Radiative diversification Species diversity Qinghai-Tibet Plateau(QTP)

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Network analysis reveals context-dependent structural complexity of social calls in serrate-legged small treefrogs

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Current Zoology 2024年第2期70卷 253-261页

作者： ke Deng Qiao-Ling He Tong-Liang Wang ji-Chao Wang jian-Guo Cui CAS key Laboratory of Mountain Ecological Restoration and Bioresource Utilization&Ecological Restoration and Biodiversity Conservation key Laboratory of Sichuan Province Chengdu Institute of BiologyChinese Academy of SciencesChengdu 610041China University of Chinese Academy of Science Beijing 100049China Ministry of Education key Laboratory for Ecology of Tropical lslands Key Laboratory of Tropical Animal and Plant Ecology of Hainan ProvinceCollege of Life SciencesHainan Normal UniversityHaikou 571158China

Vocal communication plays an important role in survival,reproduction,and animal social *** and mammals produce com-plex vocal sequence to convey context-dependent *** are conspicuous features of the behavior of most anuran species(frogs and toads),and males usually alter their calling strategies according to ecological context to improve the attractiveness/***,very few studies have focused on the variation of vocal sequence in *** the present study,we used both conventional method and network analysis to investigate the context-dependent vocal repertoire,vocal sequence,and call network structure in serrate-legged small treefrogs Kurixalus *** found that male *** modified their vocal sequence by switching to different call types and increasing repertoire size in the presence of a competitive ***,compared with before and after the playback of advertisement calls,males emited fewer advertisement calls,but more aggressive calls,encounter calls,and compound calls during the playback *** analysis revealed that the mean degree,mean closeness,and mean betweenness of the call networks significantly decreased during the playback period,which resulted in lower *** addition,the increased proportion of one-way motifs and average path length also indicated that the connectivity of the call network decreased in competitive ***,the vocal sequence of *** did not display a clear small-world network structure,regardless of *** study presents a paradigm to apply network analysis to vocal sequence in anurans and has important implications for understanding the evolution and function of sequence patterns.

关键词： call network centrality Kurixalus odontotarsus vocal repertoire vocal sequence.

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Floquet-Engineering Topological Phase Transition in Graphene Nanoribbons by Light

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Chinese Physics Letters 2024年第9期41卷 69-87页

作者： Anhua Huang Shasha ke.ji-Huan Guan Jun Li Wen-Kai Lou SKLSM Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China College of Materials Science and Opto-electronic Technology Center of Materials Science and Optoelectronics EngineeringUniversity of Chinese Academy of SciencesBeijing 100049China Department of Physics School of Physical Science and TechnologyXiamen UniversityXiamen 361005China

Quasi-one-dimensional(1D)graphene nanoribbons(GNRs)play a crucial role in advancement of nextgeneration *** studies have suggested their potential to exhibit unique symmetry-protected topological phases defined by a𝑍2 *** employing both the tight-binding model and the Floquet theory,our investigation demonstrates the effective control of the topological phase within quasi-1D armchair GNRs(AGNRs)using elliptically polarized light,unveiling rich topological phase ***,we observe that varying the amplitude of the light can induce transitions in the band gap(𝐸g)of AGNRs,leading to multiple changes in the system’s𝑍2 ***,for heterojunctions composed of different AGNR segments,the junction state can be either created or eliminated by the application of elliptically polarized light.

关键词： topological polarized Transition

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Diabetes and susceptibility to COVID-19:Risk factors and preventive and therapeutic strategies

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World Journal of Diabetes 2024年第8期15卷 1663-1671页

作者： jing-Wen Liu Xiao Huang Ming-ke Wang ji-Shun Yang School of Pharmacy Bengbu Medical UniversityBengbu 233000Anhui ProvinceChina Naval Medical Center Naval Medical UniversityShanghai 200052China

Coronavirus disease 2019(COVID-19)is a highly infectious disease caused by a novel human coronavirus called severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).Diabetes is a well-known risk factor for infectious diseases with high prevalence and increased ***,we elucidated the possible factors for the increased vulnerability of diabetic patients to SARS-CoV-2 infection and the more severe COVID-19 *** worsened prognosis of patients with both COVID-19 and diabetes may be attributable to host receptor angiotensinconverting enzyme 2-assisted viral ***,insulin resistance is often associated with impaired mucosal and skin barrier integrity,resulting in microbiota dysbiosis,which increases susceptibility to viral *** may also be associated with higher levels of pro-inflammatory cytokines resulting from an impaired immune system in diabetics,inducing a cytokine storm and excessive *** review describes diabetes mellitus and its complications,explains the risk factors,such as disease characteristics and patient lifestyle,which may contribute to the high susceptibility of diabetic patients to COVID-19,and discusses preventive and therapeutic strategies for COVID-19-positive diabetic patients.

关键词： Diabetes mellitus SARS-CoV-2 COVID-19 Susceptibility Prevention Treatment

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Demethylase-assisted site-specific detection of N^(1)-methyladenosine in RNA

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Chinese Chemical Letters 2024年第5期35卷 397-401页

作者： Jun Xiong ke-ke Chen Neng-Bin Xie Wei Chen Wen-Xuan Shao Tong-Tong ji Si-Yu Yu Yu-Qi Feng Bi-Feng Yuan College of Chemistry and Molecular Sciences Research Center of Public HealthRenmin Hospital of Wuhan UniversitySchool of Public HealthWuhan UniversityWuhan 430071China Department of Laboratory Medicine Zhongnan Hospital of Wuhan UniversityWuhan UniversityWuhan 430071China

The dynamic RNA modifications have been viewed as new posttranscriptional regulator in modulating gene expression as well as in a broad range of physiological processes.N^(1)-methyladenosine(m^(1)A)is one of the most prevalent modifications existing in multiple types of ***-depth investigation of the functions of m^(1)A requires the site-specific assessment of m^(1)A stoichiometry in ***,we established a demethylase-assisted method(DA-m^(1)A)for the site-specific detection and quantification of m^(1)A in RNA.N^(1)-methyl group in m^(1)A could result in the stalling of reverse transcription at m^(1)A site,thus producing the truncated *** AlkB is a demethylase that can demethylate m^(1)A to produce adenine in RNA,thus generating full-length cDNA from AlkB-treated *** of the produced amounts of full-length cDNA by quantitative real-time PCR can achieve the site-specific detection and quantification of m^(1)A in *** the DA-m^(1)A method,we examined and successfully confirmed the previously well-characterized m^(1)A sites in various types of RNAs with low false positive *** addition,we found that the level of m^(1)A was significantly decreased at the bromodomain containing 2(BRD2)mRNA position 1674 and CST telomere replication complex component 1(CTC1)mRNA position 5643 in human hepatocellular carcinoma *** results suggest that these two m^(1)A sites in mRNA may be involved in liver *** together,the DA-m^(1)A method is simple and enables the rapid,cost-effective,and site-specific detection and quantification of m^(1)A in RNA,which provides a valuable tool to decipher the functions of m^(1)A in human diseases.

关键词： N^(1)-methyladenosine RNA modification AlkB demethylase RNA epigenetics Quantitative real-time PCR Hepatocellular carcinoma

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Effects of phosphorus limitation on sinking velocities of phytoplankton during summer in the Changjiang River Estuary

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Acta Oceanologica Sinica 2024年第6期43卷 131-141页

作者： Xinchi You Qiang Hao jie Zhu Wei Zhang Haiyan jin Dewang Li Huanhong ji Yu ke Feng Zhou Ocean College Zhejiang UniversityZhoushan 316021China State key Laboratory of Satellite Ocean Environment Dynamics Second Institute of OceanographyMinistry of Natural ResourcesHangzhou 310000China key Laboratory of Marine Ecosystem Dynamics Second Institute of OceanographyMinistry of Natural ResourcesHangzhou 310012China Donghai Laboratory Zhoushan 316021China East China Sea Ecological Center Ministry of Natural ResourcesShanghai 201206China key Laboratory of Marine Ecological Monitoring and Restoration Technologies Ministry of Natural ResourcesShanghai 201206China Observation and Research Station of Yangtze River Delta Marine Ecosystems Ministry of Natural ResourcesZhoushan 316021China

The sinking of phytoplankton is critical to organic matter transportation in the ocean and it is an essential process for the formation of coastal hypoxic *** study was based on a field investigation conducted during the summer of 2022 in the Changjiang River(Yangtze River) Estuary(CJE) and its adjacent *** settling column method was employed to measure the sinking velocity(SV) of different size fractions of phytoplankton at the surface of the sea and to analyze their environmental control *** findings reveal significant spatial variation in phytoplankton SV(-0.55-2.41 m/d) within the ***-speed sinking was predominantly observed in phosphate-depleted regions beyond the CJE *** the same time,an upward trend was more commonly observed in the phosphate-rich regions near the CJE *** SV ranges for different sizefractionated phytoplankton,including micro-(>20 μm),nano-(2-20 μm),and picophytoplankton(0.7-2 μm),were-0.50-4.74 m/d,-1.04-1.59 m/d,and-1.24-1.65 m/d,*** analysis revealed a significant negative correlation between SV and dissolved inorganic phosphorus(DIP),implying that the influence of DIP contributes to *** variations in phytoplankton alkaline phosphatase activity suggested a significant increase in SV across all size fractions in the event of phosphorus *** communities with limited photo synthetic capacity(maximum photochemical efficience,Fv/Fm ked decrease in SV following phosphate *** findings suggest that phosphorus limitation is the primary driver of elevated SV in the *** study enhances the comprehension of the potential mechanisms underlying hypoxic zone formation in the CJE,providing no

关键词： phytoplankton sinking velocity Changjiang River Estuary phosphorus limitation alkaline phosphatase

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Fast X-ray imaging beamline at SSRF

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Nuclear Science and Techniques 2024年第9期35卷 68-81页

作者： ke Li Hong-Lan Xie Ya-Nan Fu Fei-Xiang Wang Guo-Hao Du jian-Feng ji Biao Deng Ti-Qiao Xiao Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China

The fast X-ray imaging beamline(BL16U2)at Shanghai Synchrotron Radiation Facility(SSRF)is a new beamline that provides X-ray micro-imaging capabilities across a wide range of time scales,spanning from 100 ps toμs and *** beamline has been specifically designed to facilitate the investigation of a wide range of rapid phenomena,such as the deformation and failure of materials subjected to intense dynamic *** addition,it enables the study of high-pressure and high-speed fuel spray processes in automotive *** light source of this beamline is a cryogenic permanent magnet undulator(CPMU)that is cooled by liquid *** CPMU can generate X-ray photons within an energy range of 8.7-30 *** beamline offers two modes of operation:monochromatic beam mode with a liquid nitrogen-cooled double-crystal monochromator(DCM)and pink beam mode with the first crystal of the DCM out of the beam *** X-ray imaging methods were implemented in BL16U2:single-pulse ultrafast X-ray imaging,microsecond-resolved X-ray dynamic imaging,millisecond-resolved X-ray dynamic micro-CT,and high-resolution quantitative ***,BL16U2 is equipped with various in situ impact loading systems,such as a split Hopkinson bar system,light gas gun,and fuel spray *** the completion of the final commissioning in 2021 and subsequent trial operations in 2022,the beamline has been officially available to users from 2023.

关键词： Multiple time-scale X ray imaging Single-pulse X ray imaging Dynamic 2D imaging Dynamic micro-CT

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