检索结果-南通市图书馆

Open-Shell Oligomers and Polymers: Theory, Characterization Methods, Molecular Design, and Applications

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2024年第4期42卷 417-436页

作者： Xue-qing Wang Cheng song Ting Lei key Laboratory of Polymer Chemistry and Physics(Ministry of Education) School of Materials Science and EngineeringPeking UniversityBeijing100871China

Open-shell oligomers and polymers have exhibited intriguing electronic and magnetic properties, making them highly desirable for a wide range of applications, including ambipolar organic field-effect transistors (OFETs), photodetectors, organic thermoelectrics, and spintronics. Although open-shell ground states have been observed in certain small molecules and doped organic semiconductors, the exploration of open-shell ground-state conjugated polymers is still limited, and the strategies for designing these polymers remain obscure. This review aims to briefly introduce the theory and characterization methods of open-shell conjugated polymers, along with an overview of recent progress and applications. The objective is to stimulate further advancements and investigations in this promising area by shedding light on the potential of open-shell conjugated polymers and the challenges that lie ahead.

关键词： Conjugated polymers Open-shell molecules High-spin ground state Donor-acceptor(D-A)polymers Optoelectronic and magnetic properties

Disruption of cyclin D1 degradation leads to the development of mantle cell lymphoma

在线全文

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2024年第7期14卷 2977-2991页

作者： ke Lu Ming Zhang Hongyu Qin Siyu Shen Haiqing song Hua Jiang Chunxiang Zhang Guozhi Xiao Liping Tong qing Jiang Di Chen Research Center for Computer-aided Drug Discovery Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China Faculty of Pharmaceutical Sciences Shenzhen Institute of Advanced TechnologyShenzhen 518055China Oncology Department Johns Hopkins University School of MedicineBaltimoreMD 21205USA Division of Spine Surgery the First Affiliated Hospital of Guangxi Medical UniversityNanning 530021China Division of Sports Medicine and Adult Reconstructive Surgery Department of Orthopedic SurgeryNanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolState Key Laboratory of Pharmaceutical BiotechnologyNanjing UniversityNanjing 210008China fWenzhou Institute University of Chinese Academy of SciencesWenzhou 325000China Department of Cardiology Basic Medicine Innovation Center for Cardiometabolic Diseases of Ministry of EducationInstitute of Cardiovascular Researchthe Affiliated HospitalSouthwest Medical UniversityLuzhou 646000China School of Medicine Southern University of Science and TechnologyShenzhen 518055China

Cyclin D1 has been recognized as an oncogene due to its abnormal upregulation in different types of ***,we demonstrated that cyclin D1 is SUMOylated,and we identified Itch as a specific E3 ligase recognizing SUMOylated cyclin D1 and mediating SUMO-induced ubiquitination and proteasome degradation of cyclin *** generated cyclin D1 mutant mice with mutations in the SUMOylation site,phosphorylation site,or both sites of cyclin D1,and found that double mutant mice developed a Mantle cell lymphoma(MCL)-like *** showed that arsenic trioxide(ATO)enhances cyclin D1 SUMOylation-mediated degradation through inhibition of cyclin D1 deSUMOylation enzymes,leading to MCL cell *** of severe combined immunodeficiency(SCID)mice grafted with MCL cells with ATO resulted in a significant reduction in tumor *** this study,we provide novel insights into the mechanisms of MCL tumor development and cyclin D1 regulation and discover a new strategy for MCL treatment.

关键词： Cyclin D1 SUMOylation Mantle cell lymphoma Arsenic trioxide SENP2 Proteasome degradation

High-responsivity on-chip waveguide coupled germanium photodetector for 2 μm waveband

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Photonics Research 2024年第1期12卷 115-122页

作者： JIANING WANG XI WANG YIHANG LI YANFU YANG qingHAI song ke XU Guangdong Provincial key Laboratory of Semiconductor Optoelectronic Materials and Intelligent Photonic Systems Harbin Institute of TechnologyShenzhen 518055China Department of Electronic&Information Engineering Harbin Institute of TechnologyShenzhen 518055China Department of Science Harbin Institute of TechnologyShenzhen 518055China

Recently,the emerging 2μm waveband has gained increasing interest due to its great potential for a wide scope of *** with the existing optical communication windows at shorter wavelengths,it also offers distinct advantages of lower nonlinear absorption,better fabrication tolerance,and larger free carrier plasma effects for silicon photonics,which has been a proven device *** much progress has been witnessed for silicon photonics at the 2μm waveband,the primary challenge still exists for on-chip *** the maturity and compatibility of the waveguide coupled photodetectors made of germanium,the 2μm regime is far beyond its cutoff *** this work,we demonstrate an efficient and high-speed on-chip waveguidecoupled germanium photodetector operating at the 2μm *** weak sub-bandgap absorption of epitaxial germanium is greatly enhanced by a lateral separation absorption charge multiplication *** detector is fabricated by the standard process offered by a commercial *** device has a benchmark performance with responsivity of 1.05 A/W and 3 dB bandwidth of 7.12 GHz,which is able to receive high-speed signals with up to 20 Gbit/s data *** availability of such an efficient and fast on-chip detector circumvents the barriers between silicon photonic integrated circuits and the potential applications at the 2μm waveband.

关键词： waveguide responsivity wave

Nonlinear Filtering With Sample-Based Approximation Under Constrained Communication:Progress, Insights and Trends

在线全文

学校读者我要写书评

暂无评论

IEEE/CAA Journal of Automatica Sinica 2024年第7期11卷 1539-1556页

作者： Weihao song Zidong Wang Zhongkui Li Jianan Wang qing-Long Han IEEE the State key Laboratory for Turbulence and Complex Systems Department of Mechanics and Engineering ScienceCollege of Engineering Peking University the Department of Computer Science Brunel University London the School of Aerospace Engineering Beijing Institute of Technology the School of Science Computing and Engineering Technologies Swinburne University of Technology

The nonlinear filtering problem has enduringly been an active research topic in both academia and industry due to its ever-growing theoretical importance and practical *** main objective of nonlinear filtering is to infer the states of a nonlinear dynamical system of interest based on the available noisy measurements. In recent years, the advance of network communication technology has not only popularized the networked systems with apparent advantages in terms of installation,cost and maintenance, but also brought about a series of challenges to the design of nonlinear filtering algorithms, among which the communication constraint has been recognized as a dominating concern. In this context, a great number of investigations have been launched towards the networked nonlinear filtering problem with communication constraints, and many samplebased nonlinear filters have been developed to deal with the highly nonlinear and/or non-Gaussian scenarios. The aim of this paper is to provide a timely survey about the recent advances on the sample-based networked nonlinear filtering problem from the perspective of communication constraints. More specifically, we first review three important families of sample-based filtering methods known as the unscented Kalman filter, particle filter,and maximum correntropy filter. Then, the latest developments are surveyed with stress on the topics regarding incomplete/imperfect information, limited resources and cyber ***, several challenges and open problems are highlighted to shed some lights on the possible trends of future research in this realm.

关键词： Communication constraints maximum correntropy filter networked nonlinear filtering particle filter sample-based approximation unscented Kalman filter

The medium-temperature dependence of jet transport coefficient in high-energy nucleus-nucleus collisions

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第7期35卷 173-191页

作者： Man Xie qing-Fei Han En-ke Wang Ben-Wei Zhang Han-Zhong Zhang key Laboratory of Atomic and Subatomic Structure and Quantum Control(MOE) Guangdong Basic Research Center of Excellence for Structure and Fundamental Interactions of MatterInstitute of Quantum Matter South China Normal UniversityGuangzhou510006China Guangdong-Hong Kong Joint Laboratory of Quantum Matter Guangdong Provincial Key Laboratory of Nuclear ScienceSouthern Nuclear Science Computing CenterSouth China Normal UniversityGuangzhou 510006China key Laboratory of Quark and Lepton Physics(MOE)and Institute of Particle Physics Central China Normal UniversityWuhan430079China

The medium-temperature T dependence of the jet transport coefficient̂q was studied via the nuclear modification factor RAA(p_(T))and elliptical flow parameter v_(2)(p_(T))for large transverse momentum p_(T) hadrons in high-energy nucleus-nucleus *** a next-to-leading-order perturbative QCD parton model for hard scatterings with modified fragmentation functions due to jet quenching controlled by q,we check the suppression and azimuthal anisotropy for large p_(T) hadrons,and extract q by global fits to RAA(pT)and v_(2)(pT)data in A+A collisions at RHIC and LHC,*** numerical results from the best fits show that q∕T^(3) goes down with local medium-temperature T in the parton jet *** with the case of a constant q∕T^(3),the going-down T dependence of q∕T^(3) makes a hard parton jet to lose more energy near T_(c) and therefore strengthens the azimuthal anisotropy for large pT *** a result,v_(2)(p_(T))for large pT hadrons was enhanced by approximately 10%to better fit the data at RHIC/*** the first-order phase transition from QGP to the hadron phase and the additional energy loss in the hadron phase,v_(2)(p_(T))is again enhanced by 5-10%at RHIC/LHC.

关键词： Jet quenching Jet transport parameter Hadron suppression Elliptic flow coefficient Energy loss asymmetry

On the Quantum Cohomology of Blow-ups of Four-dimensional Quadrics

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2024年第1期40卷 313-328页

作者： Jian Xun HU Hua Zhong ke Chang Zheng LI Lei song School of Mathematics Sun Yat-sen UniversityGuangzhou 510275P.R.China

We propose a conjecture relevant to Galkin’s lower bound conjecture,and verify it for the blow-ups of a four-dimensional quadric at a point or along a projective *** also show that Conjecture O holds in these two cases.

关键词： Quantum cohomology blow-up quadric hypersurface

Rheological Behaviors of Polymers with Nanoparticles Tethered at Each End

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2024年第3期42卷 400-406,I0009页

作者： song-Qi Zhang Wen-qing Wang Jia-Ping Lin Li-Quan Wang Shanghai key Laboratory of Advanced Polymeric Materials Key Laboratory for Ultrafine Materials of Ministry of EducationSchool of Materials Science and EngineeringEast China University of Science and TechnologyShanghai 200237China

The polymer with nanoparticles tethered at each end is a unique model for unraveling the effect of chain ends on the polymer dynamics. We investigated the rheological behavior of this kind of polymer by using nonequilibrium molecular dynamics simulation. The effect of polymer lengths and nanoparticle radii on the complex moduli and viscosity was examined. The dependence of complex moduli on the frequency becomes less pronounced as the polymer is short or the nanoparticle is large. The shear thinning behavior was revealed for these systems, and the scaling exponent of complex viscosity with respect to the frequency was found to change from-1/2 to-3/4 as the polymer shortens or the nanoparticle enlarges. The rheological behavior was further explained by analyzing the mean square distance of nanoparticles. The simulation results were compared with the existing experimental finding, showing an agreement. The work provides information for understanding the chain end effect on polymer rheology.

关键词： Polymer rheology Modulus Viscosity Molecular dynamics

A newly proposed heatstroke-induced coagulopathy score in patients with heat illness: A multicenter retrospective study in China

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Traumatology 2024年第2期27卷 83-90页

作者： qing-Wei Lin Lin-Cui Zhong Long-Ping He qing-Bo Zeng Wei Zhang qing song Jing-Chun song Department of Critical Care Medicine The 908th Hospital of Chinese PLA Logistic Support ForcesNanchang360104Jiangsu ProvinceChina Department of Emergency Medicine The 900th Hospital of Chinese PLA Logistic Support ForcesFuzhou350000China Department of Critical Care Medicine Hainan Hospital of Chinese PLA General HospitalSanya572013Hainan ProvinceChina

Purpose:In patients with heatstroke, disseminated intravascular coagulation (DIC) is associated with greater risk of in-hospital mortality. However, time-consuming assays or a complex diagnostic system may delay immediate treatment. Therefore, the present study proposes a new heatstroke-induced coagulopathy (HIC) score in patients with heat illness as an early warning indicator for ***:This retrospective study enrolled patients with heat illness in 24 Chinese hospitals from March 2021 to May 2022. Patients under 18 years old, with a congenital clotting disorder or liver disease, or using anticoagulants were excluded. Data were collected on demographic characteristics, routine blood tests, conventional coagulation assays and biochemical indexes. The risk factors related to coagulation function in heatstroke were identified by regression analysis, and used to construct a scoring system for HIC. The data of patients who met the diagnostic criteria for HIC and International Society on Thrombosis and Haemostasis defined-DIC were analyzed. All statistical analyses were performed using SPSS ***:The final analysis included 302 patients with heat illness, of whom 131 (43.4%) suffered from heatstroke, including 7 death (5.3%). Core temperature (OR = 1.681, 95% CI 1.291 - 2.189, p ke, and therefore used to construct an HIC scoring system because of their close relation with abnormal coagulation. A total score ≥ 3 indicated HIC, and HIC scores correlated with the score for International Society of Thrombosis and Hemostasis-DIC (r = 0.8848, p ke patients. Meanwhile, the mortality rate of HIC (19.4%) was lower than that of DIC (46.7%). When HIC developed into DIC, parameters of coagulation dysfunct

关键词： Heat illness Heatstroke Coagulation disorders Diagnosis Disseminated intravascular coagulation

Pituitary metastasis from lung adenocarcinoma:A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第15期12卷 2597-2605页

作者： qing Wang Xiao-Wei Liu ke-Yu Chen Department of Critical Care Medicine Chengdu First People’s HospitalChengdu 610000Sichuan ProvinceChina Department of Neurosurgery Chengdu Second People's HospitalChengdu 610017Sichuan ProvinceChina Department of the First Clinical Medical College Lanzhou UniversityLanzhou 730000Gansu ProvinceChina Evidence Based Medicine Center School of Basic Medical SciencesLanzhou UniversityLanzhou 730000Gansu ProvinceChina

BACKGROUND Pituitary gland metastasis is an unusual event,and pituitary metastasis from lung adenocarcinoma is extremely rare and associated with poor *** date,approximately 15 cases have been *** SUMMARY Here,we present the case of a 64-year-old woman with pituitary metastasis derived from lung adenocarcinoma,which was difficult to distinguish from other sellar *** patient presented to the neurosurgery clinic with blurred vision and intermittent *** hospitalization,brain computed tomography(CT)and magnetic resonance imaging revealed a pituitary *** CT revealed irregular nodules in the basal segment of the lower lobe of the left lung,which were likely lung *** emission tomography-CT revealed a carbohydrate metabolism tumor in the lungs and sellar region,which was considered *** pathological examination of the sellar tumor revealed lung *** Excision of pituitary metastases combined with radiotherapy and chemotherapy should be a priority treatment for patients with pituitary metastasis.

关键词： Pituitary metastasis Lung adenocarcinoma Prolactin Sellar region tumors Case report