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An experimental study in etiologic effect of pancreas divisum on chronic pancreatitis and its pathogenesis

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World Journal of Gastroenterology 1998年第6期4卷 78-80页

作者： HE Hui, LU Wei fu, ke Ya zhu and ZHANG Yi Min

AIM To investigate the etiologic association of pancreas divisum (PD) with chronic pancreatitis and to clarify its pathogenesis. METHODS A PD canine model was established in 32 dogs. The dogs were randomly divided into 4 groups ( n =8). Group Ⅰ: The communicating branch between the dorsal and ventral pancreatic ducts was partly ligated. Group Ⅱa: The communicating branch was amputated and completely ligated. Group Ⅱb: The dorsal duct was amputated and ligated at 2mm distance to the minor papilla. Group Ⅲ: A sham operation without any amputation or ligation was performed. Before and after operation, the activities of serum phospholipase A2 (PLA2) and amylase (Ams) were assayed and the basal pressures of the ducts were measured when secretin was injected. Pancreatic ductography and the pathologic examination were made. RESULTS The activities of serum PLA2 and Ams in Group Ⅰ,Ⅱa and Ⅱb were significantly increased 5-80 days after operation. At sacrifice, the basal pressures of the ventral duct were significantly higher 30min-60min after provocation in Group Ⅰ, Ⅱa and Ⅱb. The pressures of the dorsal duct were significantly increased in Group Ⅱb but no difference in Group Ⅰ and Ⅱa. Under light microscopy the fibrosis of interlobus and periducts, the destruction of acini and infiltration of inflammatory cell in dorsal and ventral pancreas were found in Group Ⅱb. But in Group Ⅰ and Ⅱa, these findings were present only in ventral pancreas. The electron microscopy showed that in ventral pancreas of Groups Ⅰ and Ⅱa and the dorsal and ventral pancreas of Group Ⅱb, the rough endoplasmic reticulum of the acinar cells showed granules scaling, fusion and dilatation. The zymogen granules decreased and the mitochondria was swollen. CONCLUSION PD is one of etiologic factors in chronic pancreatitis. The pathogenesis is the functional obstruction of the minor papilla at the peak stage of secretion.

关键词： pancreatitis/etiology pancreatitis/physiopathology paucreas divism/physiopathology paucreas divism/etiology chronic diseases

Socioeconomic status is associated with worldwide stroke incidence and case-fatality rates

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Socioeconomic status is associated with worldwide stroke inc...

Staged dendrite suppression for high safe and stable lithium-sulfur batteries

2019年浙江省医学会中毒学学术大会

作者： Yu-Ming Wang ke-fu zhu Qin-Zhang Qin-Yi Zhou Wen-Jing Zhou Dan-Feng Deng Zhao-Di Wang Yun-Mei Yang Department of Geriatrics First Affiliated HospitalSchool of MedicineZhejiang University Department of Cardiology Zhejiang Hospital The Department of Mathematical Sciences University of Texas at Dallas

Objectives:Stroke has been one of the leading causes of death worldwide and a major global health *** review systematically investigated the association of stroke incidence rate as well as early(28 days or 1 month)case-fatality rate with patient socioeconomic status across the world according to the Human Development Index(HDI)***:PubMed was searched to identify relevant epidemiological studies on ***-based studies related with the incidence and early case-fatality rate of stroke between 1990 and September,2018 were *** association of incidence and case-fatality rate of stroke with HDI and its components was assessed with Spearman coefficient.A total of 83 eligible population-based articles from 36 countries were *** correlation coefficient demonstrated that there was a negative correlation between stroke incidence and HDI on a global level(r=-0.217,P=0.025).In subtype analysis,there was a significantly negative correlation between intracerebral hemorrhage(ICH) and HDI(r=-0.502,P ke(IS)(r=0.307,P=0.038).There also was a statistically significant between the early case-fatality rate and HDI on a global level(r=-0.610,Pke incidence and case-fatality ***,more medical resources and adequate policies need to emphasis on the lower socioeconomic status ***,tailored prevention programs are also required to control the risk factors of stroke in the relatively high socioeconomic regions.

关键词： Stroke Epidemiology Incidence Socioeconomic status Mortality

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Journal of Energy Chemistry 2025年第1期100卷 674-683页

作者： Jun Jiang Zhenjie Lu Yanwen Ding Shujun Liu Zhijie Qi Tian Tang Yunfan Zhang Zhiyuan Ma Jingwen Sun Liang Xue Wenyao Zhang Pan Xiong Xin Wang Junwu zhu Yongsheng fu key Laboratory for Soft Chemistry and functional Materials of Ministry of Education Nanjing University of Science and Technology Jiangsu Pylon Battery Co.Ltd

The unavoidable dendrite growth and shuttle effect have long been stranglehold challenges limiting the safety and practicality of lithium-sulfur ***,we propose a dual-action strategy to address the lithium dendrite issue in stages by constructing a multifunctional surface-negatively-charged nanodiamond layer with high ductility and robust puncture resistance on polypropylene （PP） *** uniformly loaded compact negative layer can not only significantly enhance electron transmission efficiency and promote uniform lithium deposition,but also reduce the formation of dendrite during early deposition *** importantly,under the strong puncture stress encountered during the deterioration of lithium dendrite growth under limiting current,the high ductility and robust puncture resistance（145.88 MPa） of as-obtained nanodiamond layer can effectively prevent short circuits caused by unavoidable lithium *** Li||Li symmetrical cells assembled with nanodiamond layer modified PP demonstrated a stable cycle of over 1000 h at 2 mA cm-2with a polarization voltage of only 29.3 ***,the negative charged layer serves as a physical barrier blocking lithium polysulfide ions,effectively mitigating capacity *** improved cells achieved a capacity decay of only 0.042%per cycle after 700 cycles at 3 C,demonstrating effective suppression of dendrite growth and capacity attenuation,showing promising prospect.

关键词： Lithium-sulfur batteries Staged dendrite suppression Shuttle effect Surface-negatively-charged nanodiamond

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硝化抑制剂在农业上应用的研究进展

土壤通报 2002年第4期33卷 310-315页

作者：黄益宗冯宗炜王效科张福珠中国科学院生态环境研究中心北京100085

本文综述了硝化抑制剂在农业上应用的研究进展 ,包括硝化抑制剂的种类和作用机理、硝化抑制剂对农作物生长和产量的影响以及对环境保护的作用等。

关键词：硝化抑制剂农业应用研究进展氮肥

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Bifunctional bridging capping layer enables 24.5% efficiency of perovskite solar cells with polymer-based hole transport materials

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Science China Chemistry 2025年第1期 350-359页

作者： Can zhu Yiyang Wang Lei Meng Beibei Qiu Jing Li Shucheng Qin ke Hu Xin Jiang Wenbin Lai Minchao Liu Zhe Liu Chenxing Lu Jinyuan Zhang Yongfang Li Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Organic Solids Institute of Chemistry Chinese Academy of Sciences School of Chemical Science University of Chinese Academy of Sciences key Laboratory of Solid State Optoelectronic Devices of Zhejiang Province College of Physics and Electronic Information Engineering Zhejiang Normal University key Laboratory of Photochemical Conversion and Optoelectronic Materials Technical Institute of Physics and ChemistryChinese Academy of Sciences Laboratory of Advanced Optoelectronic Materials College of Chemistry Chemical Engineering and Materials ScienceSoochow University

Developing a bridge capping layer between perovskite and hole transport layer materials（HTMs） in the n-i-p perovskite solar cells（pero-SCs） is an effective approach to modify the morphology of HTMs and passivate the perovskite ***, we select the quinoxaline-based bifunctional passivation agent, quinoxalin-6-yl-methylamine hydrochloride（Qx MACl）,as the bridging layer, and a D-A copolymer PBQ12 containing the same quinoxaline unit as an HTM for the n-i-p pero-SCs. Due to the π-π stacking among the common quinoxaline units in the bridge layer and HTM, Qx MACl induces the π-π stacking of the PBQ12 film and improves the film morphology of HTMs with better conductivity. Additionally, Qx MACl can effectively passivate the perovskite surface, and PBQ12 possesses appropriate energy levels and high hole mobility. The pero-SCs based on FAPbI3with PBQ12/Qx MACl treatment showed a higher power conversion efficiency（PCE） of 24.05% and outstanding stability, maintaining 95.4% and 92.1% of its initial PCE after 750 h of storage and after over 800 h of thermal annealing at 85 °C, respectively. To further enhance the PCE of the PBQ12/Qx MACl-based devices, we developed a non-metal ion dopant for the PBQ12 HTM. Through trace doping of PBQ12 HTM by the non-metal ion dopant, the PCE of the PBQ12/Qx MACl-based devices reached 25.24%（the calibrated PCE of 24.55% by the National Institute of Metrology, China）.

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Primary parenchymal squamous cell carcinoma of the kidney:A case report

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World Journal of Clinical Cases 2025年第4期13卷 34-40页

作者： Zhi-Hui Zheng Bo Shao Chao-Min Xu ke Wang Jia-zhu Wen Li-Kang Luo Jia-Cheng Guan Department of Ultrasound The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Department of Radiology Shulan(Quzhou)HospitalQuzhou 324000Zhejiang ProvinceChina Department of Radiology The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Department of Pathology The Second people’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina

BACKGROUND Primary squamous cell carcinoma(SCC)of the renal parenchyma is extremely rare,with only nine cases *** SUMMARY This study reports a 51-year-old man with primary SCC of the renal *** patient was admitted with recurrent dull pain and discomfort in the right lumbar region,which had worsened over 2 weeks,accompanied by painful gross *** antigen(SCCA)levels were elevated,and imaging revealed a renal mass with associated *** patient underwent laparoscopic unilateral nephrectomy and lymph node *** pathology confirmed highly differentiated SCC with necrosis in the right renal parenchyma,with negative renal pelvis and *** pathological stage was *** months after surgery,the tumor recurred with involvement of the liver,right psoas major muscle,and inferior vena *** patient refused chemotherapy and succumbed to the disease 6 months postoperatively due to disease *** We report a case of primary SCC of the renal parenchyma,a rare renal *** clinical symptoms,laboratory tests,and imaging findings are nonspecific,making accurate and timely diagnosis *** to the literature,for patients with renal calculi accompanied by a renal mass,elevated serum SCCA levels,and magnetic resonance imaging showing cystic or cystic-solid masses within the kidney with pseudocapsules and heterogeneous mild enhancement,the possibility of this disease should be considered.

关键词： Renal tumor Renal parenchyma Squamous cell carcinoma Renal calculi Computed tomography Case report

Dirac cohomology of unitary representations of equal rank exceptional groups

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Science China Mathematics 2007年第4期50卷 515-520页

作者： fu-hai zhu ke LIANG School of Mathematical Sciences and LPMC Nankai UniversityTianjin 300071China

In this paper, we consider the unitary representations of equal rank exceptional groups of type E with a regular lambda-lowest K-type and classify those unitary representations with the nonzero Dirac cohomology.

关键词： Dirac cohomology unitary representation K-type exceptional group 22E46 22E47

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Tracking dynamic evolution of catalytic active sites in photocatalytic CO2 reduction by in situ time-resolved spectroscopy

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Rare Metals 2020年第6期39卷 607-609页

作者： Guo-zhu Chen ke-Jun Chen Jun-Wei fu Min Liu School of Physics and Electronics State Key Laboratory of Powder MetallurgyCentral South UniversityChangsha 410083China

In situ time-resolved spectroscopy is an effective method to monitor the catalysis reaction in real time and reveal the catalytic mechanistic *** dynamic evolution of coordination and electronic structures of catalytic active sites during the CO2 reduction reaction is still a "black box," impeding the design of high-efficiency *** a recent report published in ***.,by multiple in situ time-resolved spectroscopy.

关键词： spectroscopy. resolved catalytic

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Chemokine ligand 20 enhances progression of hepatocellular carcinoma via epithelial-mesenchymal transition

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World Journal of Gastroenterology 2015年第2期21卷 475-483页

作者： ke-zhu Hou Zhi-Qiang fu Hua Gong Department of First General Surgery Shidong Hospital

AIM: To identify the mechanisms of chemokine ligand 20(CCL20)-induced hepatocellular carcinoma(HCC) metastasis and evaluate it as a prognostic marker. METHODS: Expression of CCL20 was evaluated by immunohistochemistry in HCC tissues from 62 patients who underwent curative resection. The relationship between CCL20 expression and clinicopathologic features was analyzed. Univariate and multivariate analyses were performed to evaluate its predictive value for recurrence and survival of HCC patients. The expression levels ofepithelial-mesenchymal transition(EMT)-and signaling pathway-related proteins were evaluated by Western blotting and immunocytochemistry. The effects of CCL20 on HCC cell proliferation and migration were analyzed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenoltetrazolium bromide(MTT) and Transwell assays. RESULTS: CCL20 immunoreactivity was detected in all 62 patient specimens. CCL20 expression was associated with preoperative alpha-fetoprotein level(P = 0.043), tumor size(P = 0.000), tumor number(P = 0.008), vascular invasion(P = 0.014), and tumor differentiation(P = 0.007). Patients with high CCL20 expression had poorer recurrence-free and overall survivals compared to those with low CCL20 expression(both P ke changes in HCC cells and increased their proliferation and migration ability(P ke phenotype in HCC cells, and increased expression of phosphorylated AKT, β-catenin and vimentin, and decreased E-cadherin expression(P < 0.05). The correlation analysis revealed that high CCL20 expression in HCC tissue specimens was negatively correlated with E-cadherin expression(13.33%, 4/30), and positively correlated with vimentin(90.0%, 27/30), β-catenin(96.67%, 29/30) and p-AKT(76.67%, 23/30) ***: CCL20 expression is associated with HCC recurrence and patient survival and promotes HCC cell proliferation and migration by in

关键词： Chemokine ligand 20 Phosphoinositide kinase-3/AKT