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Blocking the Aryl Hydrocarbon Receptor Alleviates Myocardial Ischemia/Reperfusion Injury in Rats

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Current Medical Science 2022年第5期42卷 966-973页

作者： Jin-xu WANG Bei-bei WANG Shu-zhang YUAN ke xue Jin-sheng ZHANG Ai-jun XU Department of Anesthesiology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Anesthesiology Huashan Hospital of Fudan UniversityShanghai 200040China Henan University of Traditional Chinese Medicine Zhengzhou 450000China

Objective Restoring the blood perfusion of ischemic heart tissues is the main treatment for myocardial ***,the accompanying myocardial ischemia reperfusion injury(IRI)would aggravate myocardial *** studies have confirmed that aryl hydrocarbon receptor(AhR)is closely correlated to kidney and intestinal *** present study aimed to explore the relationship between AhR and myocardial *** An oxygen glucose deprivation/reoxygenation(OGD/R)model of H9c2 cells and an ischemia/reperfusion(I/R)model of Sprague-Dawley rat myocardium were ***/R cells and myocardial IRI rats were treated with different concentrations of the AhR antagonist CH-223191 or agonist 6-formylindolo[3,2-b]carbazole(FICZ).Under the conditions of normoxia and hypoxia/reoxygenation,the activity of cardiomyocytes,lactate dehydrogenase(LDH)and cell reactive oxygen species(ROS)were *** rats,myocardial pathological damage and markers of myocardial injury were *** According to the results of the cell viability,LDH and ROS tests in vitro,both CH-223191 and FICZ showed no myocardial protection under OGD/R ***,the histological staining and analysis of myocardial injury marker LDH in vitro revealed that CH-223191 could significantly reduce the myocardial *** AhR exhibited a different effect on myocardial IRI in vitro and in *** vivo,CH-223191 could significantly alleviate the myocardial IRI,suggesting that inhibition of AhR may play a role in myocardial protection,and AhR may serve as a potential treatment target for myocardial IRI.

关键词： aryl hydrocarbon receptor ischemia/reperfusion injury myocardial protection CH-223191 6-formylindolo[3,2-b]carbazole

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大型制冷站调试中的关键问题及解决方案

价值工程 2024年第25期43卷 84-86页

作者：王立伟张军王洋鲁克学周卫东山东电力建设第三工程公司青岛266100

制冷站是现代工业生产中不可或缺的设备之一,其主要设备制冷机压缩机采用磁浮轴承进行压缩气态氟利昂,具有高效、节能、安全等优点。本文主要围绕沙特红海公共事业和基础设施PPP项目制冷站调试过程中遇到的关键问题展开研究,并提出相应... 详细信息

制冷站是现代工业生产中不可或缺的设备之一,其主要设备制冷机压缩机采用磁浮轴承进行压缩气态氟利昂,具有高效、节能、安全等优点。本文主要围绕沙特红海公共事业和基础设施PPP项目制冷站调试过程中遇到的关键问题展开研究,并提出相应的解决方案。通过对实际案例分析,总结了制冷站调试过程中的典型问题及其解决方法,旨在为制冷站调试工程师提供参考和借鉴。

关键词：制冷站制冷机磁浮轴承调试问题解决方案

HPT工艺参数对Al-Zn-Mg-Cu合金强韧化机理研究

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蚌埠学院学报 2024年第2期13卷 24-29页

作者：刘海娟张家玺丁永根薛克敏安徽文达信息工程学院智能制造学院安徽合肥231201 合肥工业大学材料科学与工程学院安徽合肥230009

针对A1-Zn-Mg-Cu合金进行了HPT变参数正交实验,以探讨HPT工艺参数对合金力学性能的影响。通过多角度力学性能测试,包括抗拉强度和延伸率等,与常温试件的力学性能进行了比对,分析了变化规律;利用SEM对A1-Zn-Mg-Cu合金在高温下的断口形态... 详细信息

针对A1-Zn-Mg-Cu合金进行了HPT变参数正交实验,以探讨HPT工艺参数对合金力学性能的影响。通过多角度力学性能测试,包括抗拉强度和延伸率等,与常温试件的力学性能进行了比对,分析了变化规律;利用SEM对A1-Zn-Mg-Cu合金在高温下的断口形态进行观察,以揭示高温高压下A1-Zn-Mg-Cu合金的破坏机制。研究内容将为该技术在工业上的推广与应用奠定一定的理论与技术基础。

关键词： HPT正交实验变形工艺参数 A1-Zn-Mg-Cu合金破坏机制

A filter algorithm for multi-measurement nonlinear system with parameter perturbation

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2006年第10期7卷 1717-1722页

作者： GUO Yun-fei WEI Wei xue An-ke MAO Dong-cai School of Electrical Engineering Zhejiang University Hangzhou 310027 China Institute of Intelligence Information and Control Technology Hangzhou Dianzi University Hangzhou 310018 China

An improved interacting multiple models particle filter (IMM-PF) algorithm is proposed for multi-measurement nonlinear system with parameter perturbation. It divides the perturbation region into sub-regions and assigns each of them a particle filter. Hence the perturbation problem is converted into a multi-model filters problem. It combines the multiple meas- urements into a fusion value according to their likelihood function. In the simulation study, we compared it with the IMM-KF and the H-infinite filter; the results testify to its advantage over the other two methods.

关键词： IMM-PF Parameter perturbation Multi-measurement

Graphene-immobilized flower-like Ni3S2 nanoflakes as a stable binder-free anode material for sodium-ion batteries

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International Journal of Minerals,Metallurgy and Materials 2018年第1期25卷 88-93页

作者： Yu Han Shuang-yu Liu Lei Cui Li Xu Jian Xie xue-ke Xia Wen-Kui Hao Bo Wang Hui Li Jie Gao State key Laboratory of Advanced Transmission Technology Global Energy lnterconnection Research InstituteBeijing 102211China State key Laboratory of Silicon Materials School of Materials Science and EngineeringZhejiang UniversityHangzhou 310027China

A binder-free Ni3S2 electrode was prepared directly on a graphene-coated Ni foam （G/Ni） substrate through surface sulfiding of substrate using thiourea as the sulfur source in this work. The Ni3S2 showed a flower-like morphology and was uniformly distributed on the G/Ni surface. The flower-like Ni3S2 was composed of cross-arrayed nanoflakes with a diameter and a thickness of 1-2 μm and -50 nm, re- spectively. The free space in the flowers and the thin feature of Ni3S2 buffered the volume changes and relieved mechanical strain during re- peated cycling. The intimate contact with the Ni substrate and the fixing effect of graphene maintained the structural stability of the Ni3S2 electrode during cycling. The G/Ni-supported Ni3S2 maintained a reversible capacity of 250 mAh·g^-1 after 100 cycles at 50 mA·g^-1, demon- strating the good cycling stability as a result of the unique microstructure of this electrode material.

关键词： graphene Ni3S2 nanoflakes sodium-ion battery electrochemical performance

Monogamy of quantum correlations in the one-dimensional anisotropic XXXYYY model

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Chinese Physics B 2014年第1期23卷 60-65页

作者：徐帅宋学科叶柳 School of Physics & Material Science Anhui University

In this paper, the monogamy properties of some quantum correlations, including the geometric quantum discord, concurrence, entanglement of formation and entropy quantum discord, in the anisotropic spin-1/2 XY model with stag- gered Dzyaloshinskii-Moriya （DM） interaction have been investigated using the quantum renormalization group （QRG） method. We summarize the monogamy relation for different quantum correlation measures and make an explicit compar- ison. Through mathematical calculations and analysis, we obtain that no matter whether the QRG steps are carried out, the monogamy of the given states are always unaltered. Moreover, we conclude that the geometric quantum discord and concurrence obey the monogamy property while other quantum correlation measures, such as entanglement of formation and quantum discord, violate it for this given model.

关键词： monogamy relation geometric quantum discord entanglement of formation entropy quantum discord

径向湍性输运条件下CFETR平行热通量及包层能量沉积模拟

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核聚变与等离子体物理 2024年第1期44卷 65-71页

作者：高泽石王亚磊李彦龙田文喜才来中吴雪科连强李昕泽王占辉西安交通大学西安710049 中国科学技术大学合肥230026 核工业西南物理研究院成都610041

采用BOUT++输运程序与PFCFlux程序的耦合对CFETR包层第一壁上的能量沉积情况进行了模拟。研究发现,当湍性输运系数为50m^(2)·s^(-1)时,最外闭合磁面上的极向平均平行热通量为14058.5MW·m^(-2),进入刮削层的等离子体功率Psol的值为197.... 详细信息

采用BOUT++输运程序与PFCFlux程序的耦合对CFETR包层第一壁上的能量沉积情况进行了模拟。研究发现,当湍性输运系数为50m^(2)·s^(-1)时,最外闭合磁面上的极向平均平行热通量为14058.5MW·m^(-2),进入刮削层的等离子体功率Psol的值为197.4MW;CFETR包层第一壁上的能量沉积主要集中于真空室壁靠近中心螺线管的高场侧区域,最大热通量出现在这一区域的中间部分。

关键词： CFETR BOUT++ PFCFlux 平行热通量能量沉积

Computationally efficient channel estimation and inter-carrier interference suppression for OFDM communication systems

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The Journal of China Universities of Posts and Telecommunications 2009年第6期16卷 17-23页

作者： CAI Meng,ZHANG ke-feng,ZOU xue-cheng,LIU Hao School of Electronics of Science and Technology,Huazhong University of Science and Technology,Wuhan 430074,China School of Electronics of Science and Technology Huazhong University of Science and Technology Wuhan 430074 China

This article puts forward a novel channel estimation and inter-carrier interference（ICI） suppression method for time-varying orthogonal frequency division multiplexing（OFDM） *** proposed adaptive finite impulse response（FIR） filter utilizes the time domain correlation of the *** on the one order auto-regressive（AR） model,a modified Kalman filter is exploited to track the channel *** solving the Yule-Walker equation,the coefficient of the AR process can be obtained from zero order Bessel ***,when the channel is assumed not perfectly known,the above criterion will lead to an impractical *** deal with it,the coefficient of the AR process is taken as a *** a new state space model is deduced and *** results show that the proposed method can work effectively at the speed of 144 km/h with a phase noise of -85 dBc/Hz at 100 kHz *** proposed method yields an improvement bit error rate（BER） compared with three of the existing algorithms with much lower complexity.

关键词： channel estimation OFDM ICI phase noise Kalman filter

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靶向给药系统的研究进展

中国药科大学学报 2012年第1期43卷 9-15页

作者：柯学中国药科大学药剂学教研室南京210009

靶向给药系统一直是药剂学研究的热点,但人体内非常复杂的环境明显影响了靶向治疗的效果。为应对体内复杂环境,近年来科学家们在设计靶向给药系统时采取了多种措施,其中包括智能型给药系统和自适应性给药系统。通过对给药系统进行多重... 详细信息

靶向给药系统一直是药剂学研究的热点,但人体内非常复杂的环境明显影响了靶向治疗的效果。为应对体内复杂环境,近年来科学家们在设计靶向给药系统时采取了多种措施,其中包括智能型给药系统和自适应性给药系统。通过对给药系统进行多重复合设计,可以使给药载体顺利通过血液屏障,靶向到特定细胞,进而深入靶向到细胞器,更好地发挥药物的疗效。本文介绍了这方面的研究进展。

关键词：靶向给药系统自适应性给药系统智能型给药系统研究进展