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合成MRI在O-RADS MRI 3~5分卵巢附件肿物良恶性鉴别中的价值

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磁共振成像 2024年第5期15卷 148-153,161页

作者：李海蛟曹崑李晓婷孙楠罗瑶薛珂杨于昕孙应实北京大学肿瘤医院暨北京市肿瘤防治研究所医学影像科恶性肿瘤发病机制及转化研究教育部重点实验室北京100142 北京联影智能影像技术研究院磁共振科研合作部北京100089

目的探索合成MRI(synthetic MRI,syMRI)对卵巢-附件影像报告和数据系统(Ovarian-Adnexal Reporting and Data System,O-RADS)MRI 3~5分的卵巢附件占位良恶性鉴别的效能。材料与方法回顾性分析在2021年8月至2023年6月期间于我院就诊的10... 详细信息

目的探索合成MRI(synthetic MRI,syMRI)对卵巢-附件影像报告和数据系统(Ovarian-Adnexal Reporting and Data System,O-RADS)MRI 3~5分的卵巢附件占位良恶性鉴别的效能。材料与方法回顾性分析在2021年8月至2023年6月期间于我院就诊的100例盆腔占位患者病例及影像资料,共计附件肿块126例,所有占位的O-RADS MRI评分均为3~5分。以手术病理或至少1年的随访结果为诊断标准。所有患者均在3.0 T MRI扫描仪上进行盆腔MRI扫描,包括syMRI及扩散加权成像(diffusion-weighted imaging,DWI)序列。在附件区病灶的实性成分的最大层面勾画感兴趣区,以获得syMRI定量参数[T1、质子密度(proton density,PD)、T2^(*)、R2^(*)]及表观扩散系数(apparent diffusion coefficient,ADC)值。采用独立样本t检验或Mann-Whitney U检验比较各参数的差异,通过logistic回归分析建立syMRI及syMRI+ADC诊断模型,采用受试者工作特征(receiver operating characteristic,ROC)曲线比较各参数及模型的诊断效能,DeLong检验比较各模型ROC曲线下面积(area under the curve,AUC)的差异。结果入组100例患者共126个病灶,其中良性55例,恶性71例。T1、T2^(*)、R2^(*)及ADC值在两组间差异有统计学意义(P<0.05),其鉴别卵巢附件良恶性病变的AUC分别为0.739[95%置信区间(confidence interval,CI):0.652~0.826]、0.780(95%CI:0.698~0.862)、0.783(95%CI:0.699~0.866)及0.674(95%CI:0.576~0.772)。syMRI及syMRI+ADC模型的AUC分别为0.860(95%CI:0.791~0.929)及0.879(95%CI:0.818~0.940),二者之间差异无统计学意义,均高于ADC值(P<0.05)。结论syMRI在鉴别O-RADS MRI 3~5分卵巢附件病变的良恶性中具有很好的效能。

关键词：卵巢肿瘤磁共振成像合成MRI 卵巢-附件影像报告和数据系统鉴别诊断

Microstructural evolution and fracture mechanism of a new AlZn-Mg-Cu-Zr alloy processed by equal-channel angular pressing

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Rare Metals 2022年第10期41卷 3546-3551页

作者： Hong-Li Liu Ping Li ke-Min xue Chen-Hao Qian Rui Hua School of Materials Science and Engineering Hefei University of TechnologyHefei230009China

Equal-channel angular pressing(ECAP) is considered to be one of the most effective processing procedures to produce ultrafine-grained(UFG) materials.A new AI-ZnMg-Cu-Zr alloy was subjected to ECAP experiment in Route B_(C)(i.e.,rotated 90° in the same sense between each pass).The effect of ECAP on the microstructural evolution and fracture mechanism of the alloy was analyzed by optical microscope(OM),X-ray diffraction(XRD),tensile test(at room temperature),and scanning electron microscope(SEM).The results show that the main strengthening phase of the alloy is MgZn_(2),whose content increases apparently after ECAP,the dislocation density increases by one order of magnitude,the hardness value of the 1 pass ECAPed sample increases by 53 %,the ultimate tensile strength(UTS)increases by 29 %,and the true strain increases by 15.4 %.But the further increase in the strength with the passes increasing would cost a slight drop in the true *** morphology of the tensile dimples is converted from elongated one to equiaxed one with a uniform distribution of size and depth after pressing.

关键词： Al-Zn-Mg-Cu-Zr alloy Equal-channel angular pressing Microstructural evolution Crystallite size Mechanical properties Fracture mechanism

Synaptic remodeling in mouse motor cortex after spinal cord injury

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Neural Regeneration Research 2021年第4期16卷 744-749页

作者： ke-xue Zhang Jia-Jia Zhao Wei Chai Ji-Ying Chen Department of Pediatric Surgery Chinese PLA General HospitalBeijingChina Department of Anesthesiology Shunyi District HospitalBeijingChina Department of Orthopedics Chinese PLA General HospitalBeijingChina

Spinal cord injury dramatically blocks information exchange between the central nervous system and the peripheral nervous *** resulting fate of synapses in the motor cortex has not been well *** explore synaptic reorganization in the motor cortex after spinal cord injury,we established mouse models of T12 spinal cord hemi-section and then monitored the postsynaptic dendritic spines and presynaptic axonal boutons of pyramidal neurons in the hindlimb area of the motor cortex in *** results showed that spinal cord hemisection led to the remodeling of dendritic spines bilaterally in the motor cortex and the main remodeling regions changed over *** made previously stable spines unstable and eliminated spines more unlikely to be *** was a significant increase in new spines in the contralateral motor ***,the low survival rate of the new spines demonstrated that new spines were still *** of presynaptic axonal boutons found no significant *** results suggest the existence of synapse remodeling in motor cortex after spinal cord hemi-section and that spinal cord hemi-section affected postsynaptic dendritic spines rather than presynaptic axonal *** study was approved by the Ethics Committee of Chinese PLA General Hospital,China(approval No.201504168S)on April 16,2015.

关键词： central nervous system plasticity recovery regeneration repair spinal cord injury synapses

基于COOC平台的“医学信息分析”混合式教学满意度及影响因素研究

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教育教学论坛 2024年第1期 13-16页

作者：吕亚兰浦科学刘家秀重庆医科大学医学信息学院重庆400016

研究对“医学信息分析”课程开展混合式教学,分析学生对教学的满意度及其影响因素。通过问卷调查,采用Logistic回归分析满意度影响因素。调查结果显示学生对混合式教学满意度评价中位数和四分位数为4.39(4.00,4.92)分;研究对象对混合式... 详细信息

研究对“医学信息分析”课程开展混合式教学,分析学生对教学的满意度及其影响因素。通过问卷调查,采用Logistic回归分析满意度影响因素。调查结果显示学生对混合式教学满意度评价中位数和四分位数为4.39(4.00,4.92)分;研究对象对混合式教学带来的学习收获(58.5%)、师生互动(68.3%)和生生互动(68.3%)表示很满意。Logistic回归显示教师对COOC平台的熟悉程度显著影响教学满意度,熟悉程度越低,学生对教学的满意度越低,OR(95%CI):0.071(0.006,0.851)。学生对“医学信息分析”混合式教学的满意度较高;教师对网络学习平台的应用能力显著影响教学满意度。

关键词： COOC平台混合式教学满意度影响因素

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机器人辅助妇科肿瘤手术卫生经济学评价进展

中国药物经济学 2024年第1期19卷 35-39,43页

作者：陈春岚司雨欣浦科学重庆医科大学医学信息学院重庆400016

机器人手术系统作为新一代的微创手术系统,为妇科肿瘤学领域开展更精细、复杂的手术提供了良好的保障,优化了妇科肿瘤患者的临床疗效。然而,与传统腹腔镜或开腹手术相比,机器人辅助手术(RAS)的成本-效益引起了社会的广泛关注。本文聚焦... 详细信息

机器人手术系统作为新一代的微创手术系统,为妇科肿瘤学领域开展更精细、复杂的手术提供了良好的保障,优化了妇科肿瘤患者的临床疗效。然而,与传统腹腔镜或开腹手术相比,机器人辅助手术(RAS)的成本-效益引起了社会的广泛关注。本文聚焦国内外已发表的相关经济学评价证据,分析机器人辅助妇科肿瘤手术的经济学评价研究现状和热点,探讨目前相关研究存在的问题,并对未来发展方向进行预测,旨在为国内妇科领域手术机器人配置规划以及开展相关经济学评价提供决策和参考依据。

关键词：机器人辅助手术妇科肿瘤经济学评价成本-效果研究进展

Interchange reconnection between an active region and a coronal hole

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Research in Astronomy and Astrophysics 2014年第2期14卷 221-228页

作者： Lin Ma Zhong-Quan Qu Xiao-Li Yan Zhi-ke xue Yunnan Observatories Chinese Academy of Sciences University of Chinese Academy of Sciences

With data from the Atmospheric Imaging Assembly and the Helioseismic and Magnetic Imager onboard the Solar Dynamics Observatory, we present a mag- netic interaction between an isolated coronal hole （CH） and an emerging active re- gion （AR）. The AR emerged nearby the CH and interacted with it. Bright loops con- stantly formed between them, which led to a continuous retreat of the CH boundaries （CHBs）. Meanwhile, two coronal dimmings respectively appeared at the negative po- laxity of the AR and the east boundary of the bright loops, and the AR was partly disturbed. Loop eruptions followed by a flare occurred in the AR. The interaction was also accompanied by many jets and an arc-shaped brightening that appeared to be observational signatures of magnetic reconnection at the CHBs. By comparing the observations with the derived coronal magnetic configuration, it is suggested that the interaction between the CH and the AR excellently agreed with the model of inter- change reconnection. It appears that our observations provide obvious evidence for interchange reconnection.

关键词： Sun: activity -- Sun: corona -- Sun: magnetic fields -- Sun: evolution

Disappearance of a coronal hole induced by a filament activation

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Research in Astronomy and Astrophysics 2014年第11期14卷 1481-1490页

作者： Lin Ma Zhong-Quan Qu Xiao-Li Yan Zhi-ke xue Yunnan Observatories Chinese Academy of Sciences University of Chinese Academy of Sciences

We present a rare observation of direct magnetic interaction between an activating filament and a coronal hole （CH）. The filament was a quiescent one located at the northwest of the CH. It underwent a nonradial activation, during which filament material constantly fell and intruded into the CH. As a result, the CH was clearly destroyed by the intrusion. Brightenings appeared at the boundaries and in the interior of the CH, meanwhile, its west boundaries began to retreat and the area gradually shrank. It is noted that the CH went on shrinking after the end of the intrusion and finally disappeared entirely. Following the filament activation, three coronal dimmings （D1-D3） were formed, among which D1 and D2 persisted throughout the complete disappearance of the CH. The derived coronal magnetic configuration shows that the filament was located below an extended loop system, which obviously linked D1 to D2. By extrapolating this result, our observations imply that the interaction between the filament and the CH involved direct intrusion of the filament material to the CH and the disappearance of the CH might be due to interchange reconnection between the expanding loop system and the CH＇s open field.

关键词： Sun activity -- Sun filaments -- Sun magnetic fields -- Sun evolution

考虑配电网与电化学储能交互耦合关系的异常运行状态预警方法

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全球能源互联网 2024年第4期7卷 383-392页

作者：范培潇刘学成杨军李勇汇柯学洪华伟张抒凌武汉大学电气与自动化学院湖北省武汉市430072 国网福建省电力有限公司营销服务中心福建省福州市350001 国网福建省电力有限公司电力科学研究院福建省福州市350007

配电网稳定性直接关系到终端用户侧储能的运行质量。针对配电网异常运行场景下用户侧储能系统的安全问题,提出了一种热失控预警方法。该方法通过确立从配电网异常状态到用户侧储能的完整传导路径,识别了锂离子电池热失控的关键特征量,... 详细信息

配电网稳定性直接关系到终端用户侧储能的运行质量。针对配电网异常运行场景下用户侧储能系统的安全问题,提出了一种热失控预警方法。该方法通过确立从配电网异常状态到用户侧储能的完整传导路径,识别了锂离子电池热失控的关键特征量,包括异常电流值/电压值和异常状态持续时长。进而建立了用户侧储能的状态演化模型,分析了这些特征量对储能安全运行状态的影响。仿真结果揭示了不同异常电气量变化对储能安全的具体影响,如异常电流值/电压值与储能异常温度的高正相关性,以及异常状态持续时长的强正相关性。基于此,确定了用户侧储能热失控的触发边界,并为单相接地、两相短路、两相接地、三相短路等不同异常运行状态制定了预防、控制与应对措施。这些措施包括但不限于在故障无法及时消除时准备切断储能,以及加强线路保护建设等。该方法的应用显著提高了配电网与用户侧储能系统的安全稳定性。

关键词：配电网用户侧储能锂电池热失控状态演化模型热失控预警安全稳定性

以客户体验管理提升观众参观科技馆体验的思考——以中国科技馆为例

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自然科学博物馆研究 2024年第1期9卷 72-79页

作者：苑晓饶荣亮陈思思薛珂中国科技馆北京市100101 中国科技馆观众服务部

科技馆要成为观众喜爱的参观目的地,需要不断提升观众参观科技馆过程的体验。本文以中国科技馆为例,介绍科技馆开展客户体验管理的流程和方法:设定目标、梳理关键触点和驱动要素、采集数据、分析数据与改善行动、完善信息化平台。客户... 详细信息

科技馆要成为观众喜爱的参观目的地,需要不断提升观众参观科技馆过程的体验。本文以中国科技馆为例,介绍科技馆开展客户体验管理的流程和方法:设定目标、梳理关键触点和驱动要素、采集数据、分析数据与改善行动、完善信息化平台。客户体验管理需要通过“采集数据—分析数据—改善行动”等步骤,精准改善各触点的观众体验,形成动态的改进机制,持续改善观众参观科技馆体验。希望本文能为致力于提升科普场馆观众参观体验的同行们提供一点启发,共同促进科普事业高质量发展。

关键词：科技馆观众服务观众体验客户体验管理