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Impact of postoperative sexual function on health-related quality of life after robot-assisted radical prostatectomy

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Current Urology 2024年第2期18卷 148-154页

作者： Yuya Iwahashi Ryusuke Deguchi Satoshi Muraoka Takahito Wakamiya Shimpei Yamashita kazuro kikkawa Yasuo Kohjimoto Isao Hara Department of Urology Wakayama Medical UniversityWakayamaJapan

Background:We investigated potential disparities in health-related quality of life,particularly concerning urinary function,between patients with preserved and those with impaired sexual function after robot-assisted radical prostatectomy(RARP).Materials and methods:BetweenDecember 2012 and April 2020,704men underwent RARP in our *** study included 155 patients with a preoperative 5-item International Index of Erectile Function(IIEF-5)of≥12 points and an assessable IIEF-5 at 12 months ***-related quality of life was assessed using the 8-item Short-Form Health Survey and Expanded Prostate Cancer Index Composite(EPIC)preoperatively and at 3,6,and 12months postoperatively.A logistic regression analysis andWilcoxon rank sum tests were ***:Patients were grouped according to the median IIEF-5 score 12 months after surgery:those with preserved sexual function(n=71)and those with impaired sexual function(n=84).The mental component summary of the 8-item Short-Form Health Survey was better in the group with preserved sexual function at 6 months postoperatively than in the group with impaired sexual function(p<0.01).In the EPIC,the group with preserved sexual function performed better not only in the sexual domain but also in the urinary domain at all time points comparedwith the groupwith impaired sexual function(p<0.01).In the comparison of the urinary subdomains of the EPIC,there were no significant differences in urinary function or incontinence,but there were significant differences in urinary distress and irritative/obstructive scores(p<0.01).Conclusions:Patients with preserved postoperative sexual function after RARP showed better urinary function than those with impaired sexual ***,preserved sexual function is closely associated with urinary function.

关键词： Prostatectomy Robot-assisted radical prostatectomy Health-related quality of life Sexual function Urinary function

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All-Optical Signal Processing with Super-Continuum Generated from Optical Fibers

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光学学报 2003年第S1期23卷 21-22页

作者： kazuro Kikuchi Research Center for Advanced Science and Technology University of Tokyo 4-6-1 Komaba Meguro-Ku Tokyo 153-8904 Japan

Super-continuum (SC) generated from optical fibers has many attractive applications in optical communication systems. Discussing the mechanism of wideband and flat SC generation, we describe all-optical signal process... 详细信息

关键词：伐日 in of be on gene All-Optical Signal Processing with Super-Continuum Generated from Optical Fibers SC with

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Modified magnetic resonance angiography of the liver using sensitivity encoding in comparison with digital subtraction angiography and CT arterial portography

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Hepatobiliary & Pancreatic Diseases International 2005年第2期4卷 185-191页

作者： Masahiko Fujii Hideaki Kawamitsu kazuro Sugimura First Affiliated Hospital Zhejiang University School of Medicine Hangzhou 310003 China Division of Ra diology Kobe Graduate School of Medicine Hyogo 6500017 Japan

BACKGROUND: Over 355 patients have received ortho- topic liver transplantation ( OLT) at this hospital since 1993. Preoperative imaging studies of both hepatic vessels and parenchyma in these recipients bettered surgical plan- ning or even precluded the necessity of surgery. Here we report our preliminary results of modified magnetic reso- nance angiography ( MRA ) using sensitivity encoding ( SENSE) through comparative study with conventional digital subtraction angiography (DSA) and CT arterial por- tography (CTAP). METHODS: Sixteen patients with suspected liver diseases were included in the study. All of them received both dy- namic MRI of the liver using SENSE and digital DSA with CTAP within a two-week interval. The four-phase MRA was reconstructed from source images of the coronal dy- namic study. The arterial phase of the modified MRA was compared with DSA in the evaluation of hepatic arteries and the portal phase compared with CT portography recon- structed from source images of CTAP. In dynamic study of the liver, a fixed dose (20 ml) of contrast medium and scan timing were used. RESULTS: The main branches and variations of the hepatic arterial system were well shown on the modified MRA, al- though the marginal branches of hepatic arteries were of poor quality. The figures of portal veins on MRA were as clear as or superior to those of CTAP. In addition, the su- prarenal inferior vena cava (IVC) was well demonstrated on MRA and/or non contrast-enhanced coronal balanced fast-field echo (b-FFE) scan sequence in most cases. MRI detected most parenchymal lesions of the liver and hemo- dynamics of these lesions could be evaluated on source ima- ges of the modified MRA. MRI/MRA also serendipitously revealed several extrahepatic disease entities or variations that were not found on DSA/CTAP. CONCLUSIONS: The modified MRA using SENSE is a cost-effective modality of examination for the demonstra- tion of the whole hepatic vascular system. Combined with MRI, it has t

关键词： orthotopic liver transplantation magnetic resonance imaging magnetic resonance angiography digital subtraction angiography

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Background-Free Optical Sampling System Using Si Avalanche Photodiode as Two-Photon Absorber

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光学学报 2003年第S1期23卷 587-588页

作者： Kenji Taira Ryo Ohta Yasuyuki Ozeki Yutaka Fukuchi Kazuhiro Katoh kazuro Kikuchi Optical Device Laboratory Research Center for Advanced Science and Technology University of Tokyo 4-6-1 Komaba Meguro-Ku Tokyo 153-8904 JapanOptical Device Laboratory Research Center for Advanced Science and Technology University of Tokyo 4-6-1 Komaba Meguro-Ku Tokyo 153-8904 JapanOptical Device Laboratory Research Center for Advanced Science and Technology University of Tokyo 4-6-1 Komaba Meguro-Ku Tokyo 153-8904 JapanOptical Device Laboratory Research Center for Advanced Science and Technology University of Tokyo 4-6-1 Komaba Meguro-Ku Tokyo 153-8904 JapanOptical Device Laboratory Research Center for Advanced Science and Technology University of Tokyo 4-6-1 Komaba Meguro-Ku Tokyo 153-8904 JapanOptical Device Laboratory Research Center for Advanced Science and Technology University of Tokyo 4-6-1 Komaba Meguro-Ku Tokyo 153-8904 Japan

The introduction of a double-chopping scheme eliminates the background level in the optical sampling system, where a Si avalanche photodiode acts as a two-photon absorber. We successfully demonstrate background-free o... 详细信息

关键词： APD of for in as TPA Background-Free Optical Sampling System Using Si Avalanche Photodiode as Two-Photon Absorber EAM GHz test were dBm rate MLL

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Classification of Emphysema Subtypes: Comparative Assessment of Local Binary Patterns and Related Texture Features

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Advances in Computed Tomography 2015年第3期4卷 47-55页

作者： Mizuho Nishio Hisanobu Koyama Yoshiharu Ohno kazuro Sugimura Division of Functional and Diagnostic Imaging Research Department of Radiology Kobe University Graduate School of Medicine Kobe Japan Advanced Biomedical Imaging Research Center Kobe University Graduate School of Medicine Kobe Japan Division of Radiology Department of Radiology Kobe University Graduate School of Medicine Kobe Japan

The purpose of this study was to assess usefulness of local binary patterns (LBP) and related texture features, namely completed local binary patterns (CLBP) and local ternary patterns (LTP), for the classification of emphysema subtypes on low-dose CT images. Fifty patients (34 men and 16 women;age, 67.5 ± 10.1 years) who underwent low-dose CT (60 mAs) were included. They were comprised of 17 never smokers, 13 smokers without COPD, and 20 smokers with COPD. By consensus reading of low-dose CT images from these patients, two radiologists selected 3681 nonoverlapping regions of interest (ROIs) and annotated them as one of the following three classes: normal tissue, centrilobular emphysema, and paraseptal emphysema. From these ROIs, histogram of CT densities, LBP, CLBP, and LTP were calculated, and the 3 types of texture histograms were concatenated with the CT density histogram. These 3 types of histograms (referred to as combined LBP, combined CLBP, and combined LTP) were used to classify ROI using linear support vector machine. For each type of the combined histogram, the accuracy of classification was determined by patient-based 10-fold cross validation. The best accuracy of combined LBP, combined CLBP, and combined LTP were 81.36%, 82.99%, and 83.29%, respectively. Compared to the classification accuracies obtained with combined LBP, those with combined LTP or combined CLBP were consistently improved. In conclusion, the results of this study suggest that, on low-dose CT, LTP and CLBP were more useful for the classification of emphysema subtypes than LBP.

关键词： Emphysema COPD Texture Analysis Low-Dose CT

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Safety and efficacy of metallic stent for unresectable distal malignant biliary obstruction in elderly patients

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World Journal of Gastroenterology 2018年第1期24卷 69-75页

作者： Yuji Sakai Tomohisa Iwai Kenji Shimura Katsushige Gon Kazuya Koizumi Masashi Ijima kazuro Chiba Seigo Nakatani Harutoshi Sugiyama Toshio Tsuyuguchi Terumi Kamisawa Iruu Maetani Mitsuhiro Kida Department of Gastroenterology and Nephrology Graduate School of MedicineChiba UniversityChiba 260-8670Japan Department of Gastroenterology Kitasato University School of MedicineKanagawa 252-0375Japan Department of Gastroenterology Asahi Central HospitalChiba 289-2511Japan Division of Gastroenterology and Hepatology Department of Internal MedicineToho University Ohashi Medical CenterTokyo 153-8515Japan Gastroenterology Medicine Center Shonan Kamakura General HospitalKanagawa 247-8533Japan Department of Gastroenterology Subaru Health Insurance Society Ota Memorial HospitalGunma 373-8585Japan Department of Gastroenterology Tokyo Metropolitan Cancer and Infectious Diseases CenterKomagome HospitalTokyo 113-8677Japan

AIM To study the safety of insertion of metallic stents in elderly patients with unresectable distal malignant biliary *** Of 272 patients with unresectable distal malignant biliary obstruction, 184 patients under the age of 80 were classified into Group A, and 88 subjects aged 80 years or more were classified into Group B. The safety of metallic stent insertion, metal stent patency period, and the obstruction rate were examined in each *** In Group B, patients had a significantly worse per-formance status, high blood pressure, heart disease, cerebrovascular disease, and dementia; besides the rate of patients orally administered antiplatelet drugs or anticoagulants tended to be higher(P < 0.05). Metallic stents were successfully inserted in all patients. The median patency period was 265.000 ± 26.779(1-965) d; 252.000 ± 35.998(1-618) d in Group A and 269.000 ± 47.885(1-965) d in Group B, with no significant difference between the two groups. Metallic stent obstruction occurred in 82 of the 272(30.15%) patients; in 53/184(28.80%) patients in Group A and in 29/88(32.95%) of those in Group B, showing no significant difference between the two groups. Procedural accidents due to metal stent insertion occurred in 24/272(8.8%) patients; in 17/184(9.2%) of patients in Group A and in 7/88(8.0%) of those in Group B, with no significant difference between the two groups, *** These results suggested that metallic stents can be safely inserted to treat unresectable distal malignant biliary obstruction even in elderly patients aged 80 years or more.

关键词： Elderly patients Metallic stent Malignant biliary obstruction

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Immunoglobulin G4-related gastrointestinal diseases, are they immunoglobulin G4-related diseases?

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World Journal of Gastroenterology 2013年第35期19卷 5769-5774页

作者： Satomi Koizumi Terumi Kamisawa Sawako Kuruma Taku Tabata kazuro Chiba Susumu Iwasaki Yuka Endo Go Kuwata Koichi Koizumi Tooru Shimosegawa Kazuichi Okazaki Tsutomu Chiba Department of Internal Medicine Tokyo Metropolitan Komagome Hospital Division of Gastroenterology Tohoku University Department of Gastroenterology and Hepatology Kansai Medical University Department of Gastroenterology Kyoto University

In immunoglobulin G4(IgG4)-related disease(RD),organ enlargement or nodular lesions consisting of abundant infiltration of lymphocytes and IgG4-positive plasma cells and fibrosis are seen in various *** infiltration of many IgG4-positive plasma cells is detected in the gastric and colonic mucosa and major duodenal papilla of patients with autoimmune pancreatitis,it cannot be diagnosed as a gastrointestinal lesion involved in IgG4-RD,because none of the following is observed in these lesions:a mass-like formation;dense fibrosis;or obliterative *** on our review of the literature,there appear to be two types of IgG4-related gastrointestinal *** is a gastrointestinal lesion showing marked thickening of the wall of the esophagus and stomach,consisting of dense fibrosis with abundant infiltration of IgG4-positive plasma cells,which usually show submucosal *** other is an IgG4-related pseudotumor occurring in gastrointestinal regions such as the stomach,colon,and major duodenal papilla,showing polypoid or mass-like *** solitary IgG4-related gastrointestinal lesions that are not associated with other IgG4-RD appear to be difficult to *** is of utmost importance to rule out ***,these lesions may respond to steroid *** avoid unnecessary resection,IgG4-related gastrointestinal diseases should be considered in the differential diagnosis.

关键词： Immunoglobulin G4 Autoimmune pancreatitis Gastritis Colonic polyp Ulcerative colitis

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Comparison of DWI and PET/CT in evaluation of lymph node metastasis in uterine cancer

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World Journal of Radiology 2012年第5期4卷 207-214页

作者： Kazuhiro Kitajima Erena Yamasaki Yasushi Kaji Koji Murakami kazuro Sugimura Department of Radiology Kobe University Graduate School of Medicine Kobe 650-0017 Japan Department of Radiology Dokkyo University School of Medicine Mibu 321-0293 Japan Division of Nuclear Medicine Department of Diagnostic Radiology Keio University School of Medicine Tokyo 160-8582 Japan

AIM: To investigate diffusion-weighted imaging (DWI) and positron emission tomography and computed tomography (PET/CT) with Ⅳ contrast for the preoperative evaluation of pelvic lymph node (LN) metastasis in uterine cancer. METHODS: Twenty-five patients with endometrial or cervical cancer who underwent both DWI and PET/CT before pelvic lymphadenectomy were included in this study. For area specific analysis, LNs were divided into eight regions: both common iliac, external iliac, internal iliac areas, and obturator areas. The classification for malignancy on DWI was a focally abnormal signal intensity in a location that corresponded to the LN chains on the T1WI and T2WI. The criterion for malignancy on PET/CT images was increased tracer uptake by the ***: A total of 36 pathologically positive LN areas were found in 9 patients. With DWI, the sensitivity, specificity, positive predictive value, negative predictive value and accuracy for detecting metastatic LNs on an LN area-by-area analysis were 83.3%, 51.2%, 27.3%, 93.3% and 57.0%, respectively, while the corresponding values for PET/CT were 38.9%, 96.3%, 70.0%, 87.8% and 86.0%. Differences in sensitivity, specificity and accuracy were significant (P < 0.0005). CONCLUSION: DWI showed higher sensitivity and lower specificity than PET/CT. Neither DWI nor PET/CT were sufficiently accurate to replace lymphadenectomy.

关键词： Uterine cancer Lymph node metastasis Magnetic resonance imaging Diffusion-weighed imaging Positron emission tomography and computed tomography

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Jumbo biopsy is useful for the diagnosis of colonic prolapsing mucosal polyps with diverticulosis

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World Journal of Gastroenterology 2006年第10期12卷 1634-1636页

作者： Shingo Kato Kazutoshi Hashiguchi Ryuichi Yamamoto Mitsuru Seo Takashi Matsuura kazuro Itoh Akinori Iwashita Soichiro Miura Fukuoka Japan Self Defense Forces Hospital Japan Second Department of Internal Medicine National Defense Medical CollegeTokorozawa CityJapan Second Department of Internal Medicine National Defense Medical College Tokorozawa CityJapan KKR Hamanomachi Hospital Department of Pathology Chikushi Hospital Fukuoka UniversityJapan

We report here a case of multiple prolapsing mucosal polyps with diverticulosis in the sigmoid colon. A 52-year- old man was admitted to our hospital because of bloody diarrhea. Colonoscopy and barium enema showed multiple diverticula, markedly thickened mucosal folds and polypoid lesions with mucus on the top of them in the sigmoid colon. Endoscopic ultrasonography showed thickening of the mucosal and submucosal layers. Several endoscopic biopsy specimens were taken from the polypoid lesions. Histological examination revealed only chronic inflammatory cell infiltration. In order to obtain a definite diagnosis, we performed endoscopic jumbo biopsy for the polypoid lesions after obtaining informed consent. Histological examination revealed marked lymphocyte infiltration, hemosiderin deposits and fibromuscular obliteration in the lamina propria, features similar to those of mucosal prolapsing syndrome. After anti-diarrhetic treatment, clinical findings were improved. Thus, jumbo biopsy is useful for diagnosis and treatment of prolapsing mucosal polyps.

关键词： Colon Diverticulum Jumbo biopsy Prolapsing mucosal polyp

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基于光纤Bragg光栅的掺铒光纤激光器

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中国激光 2000年第7期27卷 581-585页

作者：郭玉彬菊池和朗长春邮电学院通信工程系长春130012 东京大学先端科学技术研究中心

研制了基于光纤Bragg光栅的掺铒单模光纤激光器。用 980nmLD作抽运源 ,在 1 56 μm波段获得了谱线宽为 0 1nm的激光输出。最大输出光功率为 1 73mW。输出功率稳定性为± 0 .0 2dB ,波长稳定性为 0 0 5dB。阈值抽运光功率为 7mW ,斜率... 详细信息

研制了基于光纤Bragg光栅的掺铒单模光纤激光器。用 980nmLD作抽运源 ,在 1 56 μm波段获得了谱线宽为 0 1nm的激光输出。最大输出光功率为 1 73mW。输出功率稳定性为± 0 .0 2dB ,波长稳定性为 0 0 5dB。阈值抽运光功率为 7mW ,斜率效率为 3%。

关键词：光纤激光器布拉格掺铒

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