检索结果-南通市图书馆

Prediction of return of spontaneous circulation in outof-hospital cardiac arrest with non-shockable initial rhythm using point-of-care testing: a retrospective observational study

在线全文

学校读者我要写书评

暂无评论

World Journal of Emergency Medicine 2023年第2期14卷 89-95页

作者： Kota shinada Hiroyuki Koami Ayaka Matsuoka Yuichiro Sakamoto Department of Emergency and Critical Care Medicine Faculty of MedicineSaga UniversitySaga CitySaga Prefecture 849-8501Japan Division of Translational Research in Intensive Care Medicine Faculty of MedicineSaga UniversitySaga CitySaga Prefecture 849-8501Japan

BACKGROUND:Out-of-hospital cardiac arrest(OHCA) is a public health concern, and many studies have been conducted on return of spontaneous circulation(ROSC) and its prognostic *** thromboelastometry(ROTEM?), a point-of-care testing(POCT) method, has been useful for predicting ROSC in patients with OHCA, but very few studies have focused on patients with non-shockable rhythm. We examined whether the parameters of POCT could predict ROSC in patients with OHCA and accompanying non-shockable ***:This is a single-center, retrospective observational study. Complete blood count,blood gas, and ROTEM POCT measurements were used. This study included patients with nontraumatic OHCA aged 18 years or older who were transported to the emergency department and evaluated using POCT between January 2013 and December 2021. The patients were divided into the ROSC and non-ROSC groups. Prehospital information and POCT parameters were compared using receiver operating characteristic(ROC) curve analysis, and further logistic regression analysis was ***:Sixty-seven and 135 patients were in the ROSC and non-ROSC groups,respectively. The ROC curves showed a high area under the curve(AUC) for K^(+) of 0.77(95%confidence interval [CI]:0.71–0.83) and EXTEM amplitude 5 min after clotting time(A5) of 0.70(95%CI:0.62–0.77). The odds ratios for ROSC were as follows:female sex 3.67(95%CI:1.67–8.04);K^(+)0.64(95%CI:0.48–0.84);and EXTEM A5 1.03(95%CI:1.01–1.06).CONCLUSION:In OHCA patients with non-shockable rhythm, K^(+) level and the ROTEM parameter EXTEM A5 may be useful in predicting ROSC.

关键词： Rotational thromboelastometry Blood coagulation disorders Extrinsic pathway Potassium

Huge capacity spacial division multiplexing transmission and integrated optical switching technologies(Invited Paper)

在线全文

学校读者我要写书评

暂无评论

Chinese Optics Letters 2016年第12期14卷 12-16页

作者： Naoya Wada Ben J.Puttnam Ruben S.Luis Werner Klaus Jun Sakaguchi Jose M.D.Mendinueta Yoshinari Awaji Satoshi shinada Hideaki Furukawa National Institute of Information and Communications Technology Tokyo 184-8795 Japan

We review the research and development of beyond Pb/s capacity space-division-multiplexed transmission technology using multi-core optical fibers for satisfying the ever-increasing traffic demand. Moreover, we present an optical packet and circuit integrated network technology to improve switching capacity and flexibility in network nodes for the rapid traffic fluctuation and the data service diversification.

关键词： switching multiplexing satisfying fluctuation traffic packet frames transmit throughput overhead

Highly-Efficient Conversion of Primary Amides to Nitriles Using Indium(III) Triflate as the Catalyst

在线全文

学校读者我要写书评

暂无评论

International Journal of Organic Chemistry 2014年第1期4卷 1-6页

作者： Tomoko Mineno Mamika shinada Kazuki Watanabe Hitoshi Yoshimitsu Hiroyuki Miyashita Hisao Kansui Laboratory of Medicinal Chemistry Faculty of Pharmacy Takasaki University of Health and Welfare Takasaki Japan Laboratory of Natural Medicines Faculty of Pharmaceutical Sciences Sojo University Kumamoto Japan Laboratory of Organic Chemistry for Life Sciences Faculty of Pharmacy Takasaki University of Health and Welfare Takasaki Japan Laboratory of Organic Chemistry Faculty of Pharmaceutical Sciences Sojo University Kumamoto Japan

Indium(III) triflate, a trivalent indium reagent, was shown to be a highly-efficient catalyst for the conversion of primary amides to the corresponding nitriles. The successful reactions required 5 mol% of indium(III) triflate, and toluene was proved to be the most suitable solvent. Various amides were subjected to this method, and each produced the corresponding nitriles in excellent yields.

关键词： Indium(III) Triflate Primary Amides Nitriles

Molecular Basis for Sesterterpene Diversity Produced by Plant Terpene Synthases

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plant Communications 2020年第5期1卷 41-52页

作者： Qingwen Chen Jianxu Li Zhixi Liu Takaaki Mitsuhashi Yuting Zhang Haili Liu Yihua Ma Juan He Tetsuro shinada Tsutomu Sato Yong Wang Hongwei Liu Ikuro Abe Peng Zhang Guodong Wang State Key Laboratory of Plant Genomics and National Center for Plant Gene Research Institute of Genetics and Developmental BiologyThe Innovative Academy of Seed DesignChinese Academy of SciencesBeijing 100101China National Key Laboratory of Plant Molecular Genetics Center for Excellence in Molecular Plant SciencesShanghai Institute of Plant Physiology and EcologyChinese Academy of SciencesShanghai 200032China Graduate School of Pharmaceutical Sciences University of Tokyo7-3-1 HongoBunkyo-kuTokyo 113-0033Japan State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China Key Laboratory of Synthetic Biology Institute of Plant Physiology and EcologyShanghai Institutes for Biological SciencesChinese Academy of SciencesShanghai 200032China University of Chinese Academy of Sciences Beijing 100039China Graduate School of Science Osaka City University3-3-138 SugimotoSumiyoshiOsaka 558-8585Japan Department of Applied Biological Chemistry Faculty of AgricultureGraduate School of Science and TechnologyNiigata University8050 Ikarashi-2Niigata 950-2181Japan

Class I terpene synthase(TPS)generates bioactive terpenoids with diverse *** synthase(sester-TPS,C25),a branch of class I TPSs,was recently identified in ***,the catalytic mechanisms of sester-TPSs are not fully ***,we first identified three nonclustered functional sester-TPSs(AtTPS06,AtTPS22,and AtTPS29)in Arabidopsis ***06 utilizes a type-B cyclization mechanism,whereas most other sester-TPSs produce various sesterterpene backbones via a type-A cyclization *** then determined the crystal structure of the AtTPS18–FSPP complex to explore the cyclization mechanism of plant *** used structural comparisons and site-directed mutagenesis to further elucidate the mechanism:(1)mainly due to the outward shift of helix G,plant sester-TPSs have a larger catalytic pocket than do mono-,sesqui-,and di-TPSs to accommodate GFPP;(2)type-A sester-TPSs have more aromatic residues(five or six)in their catalytic pocket than classic TPSs(two or three),which also determines whether the type-A or type-B cyclization mechanism is active;and(3)the other residues responsible for product fidelity are determined by interconversion of AtTPS18 and its close ***,this study improves our understanding of the catalytic mechanism of plant sester-TPS,which ultimately enables the rational engineering of sesterterpenoids for future applications.

关键词： terpenoid terpene synthase sesterterpene cyclization mechanism crystal structure

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

等离子体显示开启显示世界之梦

现代显示 2004年第3期 6-12页

作者： Tsutae shinada 杨兰兰富士通实验室东南大学显示技术研究中心

阐述彩色PDP发展的历史,PDP发展引发的新显示市场以及等离子体显示技术的前景。

关键词：等离子体显示屏壁挂电视等离子体电视

在线全文

学校读者我要写书评

暂无评论

粉末活性炭的制造

水处理信息报导 2003年第1期 37-37页

作者： shinada,Katsuhi－ko

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

尼可地尔治疗急性心衰患者的有效性和安全性

首都食品与医药 2016年第12期23卷 96-96页

作者： Akihiro Shirakabe Noritake Hata Shinya Yokoyama Takuro shinada Nobuaki Kobayashi Kuniya Asai Kyoichi Mizuno 刘栋不详 fjcc 北京四环科宝制药有限公司 100070

（接5月下）我们通过超声心动显像仪来评价左心室的几何结构变化，包括实验组和对照组的左心室体积变化。第三实验目的通过监测给药尼可地尔后血液动力学的变化来确定尼可地尔的安全性。

关键词：尼可地尔安全性心衰患者有效性急性治疗血液动力学结构变化

在线全文

学校读者我要写书评

暂无评论

尼可地尔治疗急性心衰患者的有效性和安全性

首都食品与医药 2016年第18期23卷 104-104页

作者： Akihiro Shirakabe(日本) Noritake Hata(日本) Shinya Yokoyama(日本) Takuro shinada(日本) Nobuaki Kobayashi(日本) Kuniya Asai(日本) Kyoichi Mizuno(日本) 刘栋(译) 不详北京四环科宝制药有限公司 100079

急性心衰(AHF)患者由于急性肺水肿造成急性呼吸衰竭性供氧不足逐渐或者快速转变为心衰(HF)的信号或症状。欧洲心脏病协会出版的指导原则推荐未合并极低血压的患者应用扩血管药物优于离子通道药物。急性心衰急性期运用硝酸酯类药物治疗... 详细信息

急性心衰(AHF)患者由于急性肺水肿造成急性呼吸衰竭性供氧不足逐渐或者快速转变为心衰(HF)的信号或症状。欧洲心脏病协会出版的指导原则推荐未合并极低血压的患者应用扩血管药物优于离子通道药物。急性心衰急性期运用硝酸酯类药物治疗是黄金定律,然而却少有报道尼可地尔治疗急性心衰的有效性。尼可地尔既具有类硝酸酯特性又能激活ATP-敏感的钾离子通道从而平衡静脉和动脉的舒张。文献证明肺动脉导管介入动态监测的慢性心衰患者静脉快滴尼可地尔可改善血液流变学参数。Minami等进一步研究表明,使用非介入心脏血流变监测的急性心衰患者在急性期使用尼可地尔的治疗有效性。

关键词：急性心衰尼可地尔有效性安全性