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慢性后负荷增加对先天性左室流出道梗阻患者左室心肌功能的影响

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世界核心医学期刊文摘(心脏病学分册) 2007年第9期 32-33页

作者： Lam Y.-Y. kaya m.g. Li W. 杜媛 AdultCongenital Heart Unit Royal Brompton Hospital London United Kingdom

本研究观察了压力超负荷距离对先天性主动脉缩窄和主动脉瓣狭窄(AS)患者左室(LV)功能的影响。利用m型超声和组织多普勒成像(TDI)技术测定连续46例LV流出道梗阻患者(23例主动脉缩窄和23例AS)

关键词：患者 AS 主动脉缩窄主动脉狭窄先天性心脏病后负荷压力负荷收缩幅度收缩速度功能

mineralogy,m-type tetrad effect and radioactivity of altered granites at the *** garadi shear zone,central Eastern Desert,Egypt

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Chinese Journal Of geochemistry 2011年第2期30卷 153-164页

作者： El Nahas H.A. El Feky m.g. mira H. Nuclear materials Authority P.O. Box 530 Cairo Egypt

The g. Abu garadi area is covered mainly by metasediments, alkali feldspar granites and stream sediments. The alkali feldspar granite is traversed by a major strike-slip fault trending in an N-S direction as well as two subordinate sets of faults trending NW to WNW for the first one and NE for the second one. These faults represent the shear zones affected by m.g.atic (syngenetic) as well as hydrothermal (epigenetic) activities causing alteration of the granitic rocks. The most common alteration features are albitization, greisenization and koalinitization. The mass balance calculations of the studied altered samples show enrichments in Zr, Y, Ni, U, Th and ga and depletions in Zn, Sr, Nb, Ba, Pb, Cu and V. Only the greisenized samples exhibit a significant enrichment in Nb, ∑REE budget and pronounced lanthanide tetrad effect (m-type), especially TE1,4, while weakly expressed tetrad effects are for the other albitized and koalinitized samples. mineralogically, the common accessory minerals in the altered samples include samarskite-(Y), betafite, uranothorite, zircon, fluorite and cassiterite. The greisenized granites contain high eU and eTh than the other altered types, where they are characterized by an assemblage of the radioactive minerals; samarskite-(Y), betafite, uranothorite in addition to zircon. The inter-element relationships between U and Th and also their ratios illustrate that the radioelement distribution in these granites is mainly governed by m.g.atic processes, in addition to post-m.g.atic ones. The distribution of chemical elements and the fractionation of some isovalents within the shear zone are largely controlled by the newly formed mineral phases. With respect to uranium mobilization, uranium m.g.ated from the host alkali feldspar granites of g. Abu garadi, while the shear zones acted as traps for the m.g.ated uranium. moreover, U m.g.ated in the shear zone during greisenization and albitization, and m.g.ated out during koalinitization.

关键词： m 类型四个效果改变的花岗石 g。Abu garadi 砍地区中央东方沙漠埃及

ON THE CONVERgENCE OF PROJECTOR-SPLINES FOR THE NUmERICAL EVALUATION OF CERTAIN TWO-DImENSIONAL CPV INTEgRALS

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Journal of Computational mathematics 2002年第2期20卷 113-120页

作者： Santi, Elisabetta Cimoroni, m.g. Department of Energetica University of L'Aquila-67040 Roio Poggio-L'Aquila 意大利

Focuses on a study that proposed product formulas based on projector-splines for the numerical evaluation of two-dimensional Cauchy principal value integrals. Preliminaries; Convergence of quadrature rules using proje... 详细信息

关键词： D Cauchy principal value integral Tensor product projector-splines.

SYNTHESIS,CHARACTERIZATION,THERmAL DEgRADATION AND ELECTROCHEmICAL PROPERTIES OF OLIgO-4-m-TOLYLAZOmETHINEPHENOL

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Chinese Journal of Polymer Science 2006年第6期24卷 647-656页

作者： smet kaya Yasin Bayrakli Department of Chemistry Faculty of Sciences and Artsanakkale Onsekiz Mart UniversityTR-17020 anakkaleTurkey

The oxidative polycondensation reaction conditions of 4-m-tolylazomethinephenol （4-TAmP） in the presence of air O2 and NaOCl as oxidants were studied in an aqueous alkaline medium between 50 and 90℃. The structures of the obtained monomer and oligomer were confirmed by FT-IR, UV-Vis, ^1H- and ^13C-NmR and elemental analysis techniques. The physical characterization was made by Tg-DTA, size exclusion chromatography （SEC） and solubility tests. At the optimum reaction conditions, the yield of oligo-4-m-tolylazomethinephenol （O-4-TAmP） was found to be 62.50% （for air O2 oxidant） and 90.0% （for NaOCl oxidant）, respectively. According to the SEC analysis, the number-average molecular weight （mn）, weight-average molecular weight （mw） and polydispersity index （PDI） values of O-4-TAmP were found to be 2310, 2610 g tool 1 and 1. 13, respectively, using air O2, and 1390, 1710 g mol^-1 and 1.23, using NaOCl, respectively. According to Tg-DTA analyses, O-4-TAmP was more stable than 4-TAmP against thermal decomposition. The weight losses of 4-TAmP and O-4-TAmP were found to be 68% and 58% at 1000℃. Electrical conductivity of the O-4-TAmP was measured, showing that the polymer is a typical semiconductor. Electrochemically, the highest occupied molecular orbital （HOmO）, the lowest unoccupied molecular orbital （LUmO） and electrochemical energy gaps （E＇g） for 4-TAmP are -5.96, -3.22 and 2.74 eV, respectively. The HOmO, LUmO and （E＇g） for O-4-TAmP are -5.78, -3.44 and 2.34 eV, respectively. According to UV-Vis measurements, optical band gaps （Eg） of 4-TAmP and O-4-TAmP were found to be 3.45 and 3. 1 0 eV, respectively.

关键词： Air O2 NaOCl Oligo-4-m-tolylazomethinephenol Oxidative polycondensation Thermal analysis Band gap Conductivity

mineralogical, REE-geochemical and fluid inclusion studies on some uranium occurrences, gabal gattar, Northeastern Desert, Egypt

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Chinese Journal Of geochemistry 2011年第4期30卷 430-443页

作者： El-Feky m.g. Nuclear materials Authority

Altered granite occurrences (gII and gV) at gabal (g.) gattar are the most important mineralized rocks hosting U-mineralization in Egypt. This mineralized granite is affected by multi-stage hydrothermal alteration proc-esses along brittle structures. This alteration comprises pre-ore alkali-metasomatism and ore-stage hydrothermal hematitization, silicification, kaolinitization, fluoritization, carbonatization and episyenitization. Autoradiographic examination indicates that primary uranium mineralization is present as massive or disseminated ores along tectonic fractures, interstitially in granular minerals, and as cements of breccias. Uraninite, pitchblende and coffinite are the main primary minerals, while uranophane and kasolite are the secondary ones. galena, chalcopyrite, pyrrohtite and pyrite are the most abundant sulphides in association with uranium mineralizations. Hydrothermal alterations at the gII occurrence exhibit an increase in Ni, Cu, Zn, Pb, mo, Nb, Rb beside HREEs and a decrease in Ba, Co, Sr, and V, while alterations at the gV occurrence show enrichment in Ni, Cu, Pb, mo, Nb, Y, HREEs and depletion in Zn, Ba, Co, Rb, Sr, and V. Hydrothermal alteration during the late m.g.atic stage is also identified through the development of unusual REE patterns and fractionation of ratios like Zr/Hf and Y/Ho out of the CHARAC (Charge Radius Con-trolled) range. Non-chondritic Y/Ho ratio at gV is of larger value than chondritic one which may result from wa-ter-rock interaction or print from the encompassing sedimentary rocks. Fluid inclusion studies on quartz and fluorite revealed that temperatures of the mineralizing fluids range between 126 and 240℃ at pressure ≤0.5×108 Pa and give salinity values ranging between 1 wt% and 7.8 wt% NaCl equivalent.

关键词：稀土元素地球化学流体包裹体铀矿化矿物学埃及全球信息基础设施东北部沙漠

Heterogeneity of mature oligodendrocytes in the central nervous system

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Neural Regeneration Research 2025年第5期20卷 1336-1349页

作者： Chao Weng Adam m.R.groh moein Yaqubi Qiao-Ling Cui Jo Anne Stratton g.R.Wayne moore Jack P.Antel Neuroimmunology Unit Montreal Neurological Institute-HospitalDepartment of Neurology and NeurosurgeryMcGill UniversityMontrealQCCanada Department of Neurology Renmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina

mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous *** evidence has challenged the classical view of the functionally static mature oligodendrocyte and revealed a gamut of dynamic functions such as the ability to modulate neuronal circuitry and provide metabolic support to *** the recognition of potential heterogeneity in mature oligodendrocyte function,a comprehensive summary of mature oligodendrocyte diversity is *** delve into early 20th-century studies by Robertson and Río-Hortega that laid the foundation for the modern identification of regional and morphological heterogeneity in mature ***,recent morphologic and functional studies call into question the long-assumed hom.g.neity of mature oligodendrocyte function through the identification of distinct subtypes with varying myelination ***,modern molecular investigations,employing techniques such as single cell/nucleus RNA sequencing,consistently unveil at least six mature oligodendrocyte subpopulations in the human central nervous system that are highly transcriptomically diverse and vary with central nervous system *** and disease related mature oligodendrocyte variation denotes the impact of pathological conditions such as multiple sclerosis,Alzheimer's disease,and psychiatric ***,caution is warranted when subclassifying mature oligodendrocytes because of the simplification needed to make conclusions about cell identity from temporally confined *** studies leveraging advanced techniques like spatial transcriptomics and single-cell proteomics promise a more nuanced understanding of mature oligodendrocyte *** research avenues that precisely evaluate mature oligodendrocyte heterogeneity with care to understand the mitigating influence of species,sex,central nervous system region,age,and disease,

关键词： aging central nervous system diseases electron microscopy heterogeneity immunohistochemistry myelin sheath natural history neuroglia oligodendroglia single-cell gene expression analysis

Effect of sodium replacement on the quality characteristics of pastırma(a dry-cured meat product)

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Food Science and Human Wellness 2023年第1期12卷 266-274页

作者： BarışYalınkılıç güzin Kaban mükerrem kaya Department of gastronomy and Culinary Arts Faculty of Fine Arts and Architectureİstanbul Gedik UniversityKartalIstanbul 34876Turkey Department of Food Engineering Faculty of AgricultureAtatürk UniversityErzurum 25240Turkey

This study aims to investigate the effect of sodium replacement on the quality characteristics of pastı*** this purpose,pastırma production with four different salt mixtures(Ⅰ.100%NaCl;Ⅱ.50%NaCl+50%KCl;Ⅲ.40%NaCl+40%KCl+20%CaCl_(2);Ⅳ.30%NaCl+40%KCl+20%CaCl_(2)+10%mgCl_(2))were carried out using traditional *** use of different salt mixtures for pastırma had no statistically significant effect on the microbial counts and residual nitrite of the final *** a*and b*values were affected by this *** salt mixture containing CaCl_(2) or CaCl_(2)+mgCl_(2) significantly decreased the pH values and sensory *** eighteen volatile compounds were affected by the salt ***^(+),K^(+),Ca^(2+),and mg^(2+)had a certain increase depending on their ratio in the salt *** highest Cathepsin activity in all pastırma samples was observed in Cathepsin B+*** salt mixture with NaCl+KCl+CaCl_(2)+mgCl_(2) increased acid lipase ***,this mixture had no significant effect on neutral lipase activity.

关键词： Pastırma Chloride salts Volatile compounds Cathepsin Lipase

SCIENTIFIC PRINCIPLES FOR mODIFICATION OF WATER-SOLUBLE POLYmERS. FORmATION OF mACROmOLECULAR COmPLEXES

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Chinese Journal of Polymer Science 1998年第3期16卷 268-278页

作者： PAUTOV V.D. ANUFRIEVA E.V. KRAKOVYAK m.g. Institute of macromolecular Compounds RAS Bolshoy pr. 31 St. Petersburg 199004 RussiaInstitute of Macromolecular Compounds RAS Bolshoy pr. 31 St. Petersburg 199004 RussiaInstitute of Macromolecular Compounds RAS Bolshoy pr. 31 St. Petersburg 199004 Russia

The study of nanosecond dynamics of macromolecules with the lumines-cent methods make it possible to investigate the formation and functioning of polymericcomplexes, polymeric conjugates and macromolecular metal complexes, which are widelyused for solving many practical tasks. The nanosecond dynamics of macromolecules are ahighly sensitive indicator of interpolymer complexes (IPC) formation. It enables us to solvethe problems of studying IPC formation and stability and to investigate the interpolymerreactions of exchange and substitution. The investigation of changes in the rotational mo-bility of globular protein molecules as a whole makes it possible to determine the complexcomposition and its stability, and to control the course of polymer-protein conjugate forma-tion reaction. The nanosecond dynamics of polymers interacting with surfacants' ions (S)are the sensitive indicator of the S-polymer complex formation. A method for determin-ing the equilibrium constants of the S-polymer complex formation was developed on thebasis of the study of polymer chains mobility. It is established that nanosecond dynamicsinfluences the course of chemical reactions in polymer chains. moreover, the marked effectof the nanosecond dynamics is also revealed in the study of photophysical processes (theformation of excimers and energy m.g.ation of electron excitation) in polymers with pho-toactive groups. It was found that the efficiency of both processes increases with increasingthe mobility of side chains, the carriers of photoactive groups.

关键词： modification of water-soluble polymers Formation of complexes

Adult neurogenesis in the mammalian brain

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Frontiers in Biology 2013年第3期8卷 295-304页

作者： Simon m.g. BRAUN Sebastian JESSBERgER Brain Research Institute Faculty of Medicine University of Zurich 8057 Zurich Switzerland Neuroscience Center Zurich University of Zurich and ETH Zurich Switzerland

New neurons are generated throughout life in distinct areas of the mammalian brain. This process, called adult neurogenesis, has challenged previously held concepts about adult brain plasticity and opened novel therapeutic avenues to treat certain neuro-psychiatric diseases. Here, we review the current knowledge regarding the fate and potency of neural stem cells （NSCs）, as well as the mechanisms underlying neuronal differentiation and subsequent integration. Furthermore, we discuss the functional significance of adult neurogenesis in health and disease, and offer brief insight into the future directions of the adult neurogenesis field.

关键词： adult neurogenesis hippocampus stem cell memory neuropsychiatric disease