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Integrating Conjugate Gradients Into Evolutionary Algorithms for Large-Scale Continuous Multi-Objective Optimization

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IEEE/CAA Journal of Automatica Sinica 2022年第10期9卷 1801-1817页

作者： Ye Tian Haowen chen Haiping Ma Xingyi Zhang kay chen tan Yaochu Jin the Information Materials and Intelligent Sensing Laboratory of Anhui Province Institutes of Physical Science and Information TechnologyAnhui UniversityHefei 230601China the Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefei 230601China IEEE the Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education School of Artificial IntelligenceAnhui UniversityHefei 230601China the Department of Computing The Hong Kong Polytechnic UniversityHong Kong SARChina the Faculty of Technology Bielefeld UniversityBielefeld 33619Germany

Large-scale multi-objective optimization problems(LSMOPs)pose challenges to existing optimizers since a set of well-converged and diverse solutions should be found in huge search *** evolutionary algorithms are good at solving small-scale multi-objective optimization problems,they are criticized for low efficiency in converging to the optimums of *** contrast,mathematical programming methods offer fast convergence speed on large-scale single-objective optimization problems,but they have difficulties in finding diverse solutions for ***,how to integrate evolutionary algorithms with mathematical programming methods to solve LSMOPs remains *** this paper,a hybrid algorithm is tailored for LSMOPs by coupling differential evolution and a conjugate gradient *** the one hand,conjugate gradients and differential evolution are used to update different decision variables of a set of solutions,where the former drives the solutions to quickly converge towards the Pareto front and the latter promotes the diversity of the solutions to cover the whole Pareto *** the other hand,objective decomposition strategy of evolutionary multi-objective optimization is used to differentiate the conjugate gradients of solutions,and the line search strategy of mathematical programming is used to ensure the higher quality of each offspring than its *** comparison with state-of-the-art evolutionary algorithms,mathematical programming methods,and hybrid algorithms,the proposed algorithm exhibits better convergence and diversity performance on a variety of benchmark and real-world LSMOPs.

关键词： Conjugate gradient differential evolution evolutionary computation large-scale multi-objective optimization mathematical programming

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CAutoCSD-Evolutionary Search and Optimisation Enabled Computer Automated Control System Design

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International Journal of Automation and computing 2004年第1期1卷 76-88页

作者： Kiam Heong Ang Gregory C.Y. kay chen tan Hiroshi Kashiwagi Department of Electronics and Electrical Engineering University of Glasgow Glasgow G12 8LT UKDepartment of Electronics and Electrical Engineering University of Glasgow Glasgow G12 8LT UKDepartment of Electronics and Electrical Engineering University of Glasgow Glasgow G12 8LT UKDepartment of Mechanical Engineering and Material Science Kumamoto University Japan

This paper attempts to set a unified scene for various linear time-invariant (LTI) control system design schemes, by transforming the existing concept of “computer-aided control system design” (CACSD) to novel “computer-automated control system design” (CAutoCSD). The first step towards this goal is to accommodate, under practical constraints, various design objectives that are desirable in both time and frequency domains. Such performance-prioritised unification is aimed at relieving practising engineers from having to select a particular control scheme and from sacrificing certain performance goals resulting from pre-commitment to such schemes. With recent progress in evolutionary computing based extra-numeric, multi-criterion search and optimisation techniques, such unification of LTI control schemes becomes feasible, analytical and practical, and the resultant designs can be creative. The techniques developed are applied to, and illustrated by, three design problems. The unified approach automatically provides an integrator for zero-steady state error in velocity control of a DC motor, and meets multiple objectives in the design of an LTI controller for a non-minimum phase plant and offers a high-performance LTI controller network for a non-linear chemical process.

关键词： Linear time invariant (LTI) proportional plus integral plus derivative (PID) control system design (CSD) computer aided control system design (CACSD) performance index genetic algorithms (GA) evolutionary computation (EC) process control r

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Integrating Conjugate Gradients Into Evolutionary Algorithms for Large-Scale Continuous Multi-Objective Optimization

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IEEE/CAA Journal of Automatica Sinica 2022年第10期

作者： Ye Tian Haowen chen Haiping Ma Xingyi Zhang kay chen tan Yaochu Jin

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Principled Design of Translation, Scale, and Rotation Invariant Variation Operators for Metaheuristics

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Chinese Journal of Electronics 2023年第1期32卷 111-129页

作者： TIAN Ye ZHANG Xingyi HE cheng tan kay chen JIN Yaochu Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education Institutes of Physical Science and Information Technology Anhui University School of Artificial Intelligence Anhui University School of Electrical and Electronic Engineering Huazhong University of Science and Technology Department of Computing The Hong Kong Polytechnic University Faculty of Technology Bielefeld University

A large number of metaheuristics have been proposed and shown high performance in solving complex optimization problems. While most variation operators in existing metaheuristics are empirically designed,new operators are automatically designed in this work,which are expected to be search space independent and thus exhibit robust performance on different *** work first investigates the influence of translation invariance, scale invariance, and rotation invariance on the search behavior and performance of some representative operators. This work then deduces the generic form of translation, scale, and rotation invariant operators, and proposes a principled approach for the automated design of operators, which searches for high-performance operators based on the deduced generic form. The experimental results demonstrate that the operators generated by the proposed approach outperform state-of-the-art ones on a variety of problems with complex landscapes and up to 1000decision variables.

关键词： Deep learning Metaheuristics Reinforcement learning Benchmark testing Search problems Robustness Behavioral sciences

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Plastid genome evolution of a monophyletic group in the subtribe Lauriineae(Laureae,Lauraceae)

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Plant Diversity 2022年第4期44卷 377-388页

作者： Chao Liu Huan-Huan chen Li-Zhou tang Phyo kay Khine Li-Hong Han Yu Song Yun-Hong tan College of Biological Resource and Food Engineering Yunnan Engineering Research Center of Fruit WineQujing Normal UniversityQujingYunnan655011China Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection(Ministry of Education) Guangxi Key Laboratory of Landscape Resources Conservation and Sustainable Utilization in Lijiang River BasinGuangxi Normal UniversityGuilinGuangxi541004China Center for Integrative Conservation Xishuangbanna Tropical Botanical GardenChinese Academy of SciencesMenglaYunnan666303China Southeast Asia Biodiversity Research Institute Chinese Academy of SciencesYezinNay Pyi Taw05282Myanmar

Litsea,a non-monophyletic group of the tribe Laureae(Lauraceae),plays important roles in the tropical and subtropical forests of Asia,Australia,Central and North America,and the islands of the ***,intergeneric relationships between Litsea and Laurus,Lindera,Parasassafras and Sinosassafras of the tribe Laureae remain *** this study,we present phylogenetic analyses of seven newly sequenced Litsea plastomes,together with 47 Laureae plastomes obtained from public databases,representing six genera of the *** results highlight two highly supported monophyletic groups of Litsea *** is composed of 16 Litsea taxa and two Lindera *** 18 plastomes of these taxa were further compared for their gene structure,codon usage,contraction and expansion of inverted repeats,sequence repeats,divergence hotspots,and gene *** complete plastome size of newly sequenced taxa varied between 152,377 bp(Litsea auriculata)and 154,117 bp(Litsea pierrei).Seven of the 16 Litsea plastomes have a pair of insertions in the IRa(trnL-trnH)and IRb(ycf2)*** 18 plastomes of Litsea and Lindera taxa exhibit similar gene features,codon usage,oligonucleotide repeats,and inverted repeat *** codons with the highest frequency among these taxa favored A/T endings and each of these plastomes had nine divergence hotspots,which are located in the same *** also identified six protein coding genes(accD,ndhJ,rbcL,rpoC2,ycf1 and ycf2)under positive selection in Litsea;these genes may play important roles in adaptation of Litsea species to various environments.

关键词： Litsea Phylogenetic analysis Divergent hotspots Gene evolution

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Systematic Synthesis of Dedicated Hybrid Transmission

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Automotive Innovation 2019年第3期2卷 231-239页

作者： Lin Li Haijun chen Ferit Küçükay Institute of Automotive Engineering Technische Universität BraunschweigBrunswick 38106Germany

The great diversity of dedicated hybrid transmissions(DHTs)requires a method to identify solutions among all potential concepts involved in each ***,a DHT synthesis tool is developed on the basis of general transmission *** the first synthesis step,transmission structures are generated with only conventional functions such as driving with only the internal combustion *** machines are then installed in the transmissions to achieve further hybrid functions,including boosting,eCVT and electric driving *** number of generated transmission concepts increases exponentially with each synthesis *** evaluations are carried out successively to identify the most suitable DHT concepts among the many possible *** generated DHT concepts are evaluated in terms of structural feasibility,driving modes,drivability and load factors on transmission *** example of DHT synthesis involving planetary gear sets is explained in *** best five DHT structures are identified out of more than 120 billion solutions.

关键词： Dedicated hybrid transmission Transmission design Synthesis Structural evaluation

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Clinical and socioeconomic determinants of survival in biliary tract adenocarcinomas

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1374-1383页

作者： Laura Sahyoun kay chen Cynthia Tsay George chen Petr Protiva Department of Gastroenterology and Hepatology Weill Cornell MedicineNew YorkNY 10065United States Gastroenterology Section Jennifer Moreno VA San Diego Healthcare SystemSan DiegoCA 92161United States Division of Gastroenterology Department of MedicineUniversity of California San DiegoLa JollaCA 92093United States Department of Gastroenterology and Hepatology John Hopkins HospitalBaltimoreMD 21287United States Department of Digestive Diseases Yale New Haven HospitalNew HavenCT 06520United States Department of Gastroenterology VA Connecticut Health Care SystemWest HavenCT 06516United States

BACKGROUND Despite advances in detection and treatments,biliary tract cancers continue to have poor survival ***,there is limited data investigating the significance of socioeconomic status,race/ethnicity,and environmental factors in biliary tract cancer *** from the Surveillance,Epidemiology,and End Results database for biliary and gallbladder adenocarcinomas were extracted from 1975 to ***-conomic data included smoking,poverty level,education,adjusted household income,and percentage of foreign-born persons and urban *** was calculated with Cox proportional hazards models for death in the 5-year period following *** Our study included 15883 gallbladder,11466 intrahepatic biliary,12869 extrahepatic biliary and 7268 ampulla of Vater adenocarcinoma *** analyzing county-specific demographics,patients from counties with higher incomes were associated with higher survival rates[hazard ratio(HR)=0.97,P<0.05].Similarly,counties with a higher percentage of patients with a college level education and counties with a higher urban population had higher 5-year survival rates(HR=0.96,P=0.002 and HR=0.97,P=0.004,respectively).CONCLUSION Worse survival outcomes were observed in lower income counties while higher income and education level were associated with higher 5-year overall survival among gallbladder and biliary malignancies.

关键词： Biliary tract cancers Survival Outcomes research Socioeconomic factors Healthcare disparities

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Reactive oxygen species and nitric oxide scavenging nanoparticles alleviating rheumatoid arthritis through adjusting the seeds and growing soils

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Acta Pharmaceutica Sinica B 2023年第12期13卷 5016-5029页

作者： Peng Hua Ruifeng Liang Yanbei Tu Yuying Yin Man-kay Law Meiwan chen State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoMacao SARChina State Key Laboratory of Analog and Mixed-Signal VLSI IME and FST-ECEUniversity of MacaoMacao SARChina

Normalizing inflamed soils including reactive oxygen species(ROS),nitric oxide(NO),cellfree DNA,and regulating infammation-related seeds such as macrophages,neutrophils,fibroblasts,represent a promising strategy to maintain synovial tissue homeostasis for rheumatoid arthritis(RA)***,ROS scavenging amphiphilic block copolymer PEGylated bilirubin and NO-scavenging PEGylated o-phenylenediamine were fabricated to self-assemble into a dually responsive nanoparticle loaded with JAK inhibitor notopterol(Not@BR/oPDA-PEG,NBOP NPs).The simultaneous ROS and NO depletion combined with JAK-STAT pathway inhibition could not only promote M2 polarization to reduce further ROS and NO generation,but also decrease cytokines and chemokines to prevent immune cell ***,NBOP NPs responded to high level ROS and NO,and disintegrated to release notopterol in inflamed joints as the hydrophobic heads BR and oPDA were transformed into hydrophilic *** released notopterol could inhibit the JAK-STAT pathway of infammatory cells to reduce the secretion of pro-inflammatory cytokines and *** strategy represented an effective way to regulate RA soils and seeds through breaking the positive feedback loop of inflammation aggravation,achieving an excellent anti-RA efficacy in a collagen-induced arthritis rat *** together,our work offered a reference to adjust RA soils and seeds for enhanced RA treatment.

关键词： Bilirubin o-Phenylenediamine Notopterol ROS and NO scavenging JAK-STATpathway Anti-inflammatory Cartilage protection Rheumatoid arthritis

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A Multi-Channel CMOS Analog Front-End Interface IC with 157.8 d B Current Detection Dynamic Range

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Chinese Journal of Electronics 2024年第2期33卷 393-402页

作者： Kunyu WANG Wenjing XU chengbin ZHANG Yanjun YANG Man-kay LAW Li ZHOU Jie chen Ming chen Institute of Microelectronics of the Chinese Academy of Science University of Chinese Academy of Sciences Zunyi Normal University Institute of Microelectronics and Dept.of ECE FST University of Macau

A high dynamic range and low-noise CMOS(complementary metal-oxide-semiconductor transistor)front-end interface integrated circuit(IC) with multi-channel detection is presented in this paper. Two different current detection channels, composed of a trans-impedance amplifier(TIA) and an integrator-differentiator TIA, are used to boost the current detection range. A capacitance-coupled instrument amplifier(CCIA) is also included to realize high precision voltage detection. A fourth-order sigma-delta modulator using a second-order loop filter and a second-order noise shaping integral quantizer is adopted to realize effective number of bits above 16 bits. The presented interface IC is implemented in 0.18-μm CMOS process with supply voltage of 3.3 V, and a proto-type electrochemical sensor platform with miniaturized sensor array is developed to verify the functionality of the interface IC. Measurement results indicate that the designed interface IC achieves 157.8 d B current detection dynamic range, and the measured input-referred current noise and voltage noise floor are 1.04 p A and 58.4 n V within 10 k Hz integration bandwidths,respectively.

关键词： Integrated circuits Sigma-delta modulation Semiconductor device measurement Voltage measurement Current measurement Noise Bandwidth

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Deep Neural Network-based Speaker-Aware Information Logging for Augmentative and Alternative Communication

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Journal of Artificial Intelligence and Technology 2021年第2期1卷 138-143页

作者： Gang Hu Szu-Han kay chen Neal Mazur Department of Computer Information State University of New York Buffalo StateBuffaloNY 14222 USA Department of Communication Disorders and Sciences State University of New YorkFredoniaNY 14063 USA

People with complex communication needs can use a high-technology augmentative and alternative communication device to communicate with ***,researchers and clinicians often use data logging from high-tech augmentative and alternative communication devices to analyze augmentative and alternative communication user ***,existing automated data logging systems cannot differentiate the authorship of the data log when more than one user accesses the *** issue reduces the validity of the data logs and increases the difficulties of performance ***,this paper presents a solution using a deep neural network-based visual analysis approach to process videos to detect different augmentative and alternative communication users in practice *** approach has significant potential to improve the validity of data logs and ultimately to enhance augmentative and alternative communication outcome measures.

关键词： augmentative and alternative communication(AAC) outcome measures visual logs hand tracking deep learning

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