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SARS-COV-2 infection(coronavirus disease 2019)for the gastrointestinal consultant

World Journal of Gastroenterology 2020年第14期26卷 1546-1553页

作者： kaveh hajifathalian.srihari mahadev Robert E Schwartz Shawn Shah Kartik Sampath Felice Schnoll-Sussman Robert S Brown Jr David Carr-Locke David E Cohen Reem Z Sharaiha Division of Gastroenterology and Hepatology Weill Cornell MedicineNew York-Presbyterian HospitalNew YorkNY 10021United States

The current pandemic due to the severe acute respiratory syndrome coronavirus 2 has caused an extreme burden for health care systems globally,and the number of cases is expected to continue to increase,at least in the immediate *** virus is estimated to have infected more than 1.5 million *** available reports suggest that gastrointestinal(GI)involvement in coronavirus disease 2019(COVID-19)is common and in some cases the GI symptoms may precede the respiratory *** addition to direct effects of severe acute respiratory syndrome coronavirus 2,the infected patients remain at risk for the complications commonly managed by gastroenterology and hepatology *** most commonly reported GI manifestation of COVID-19 is diarrhea,which is reported in a third to up to more than half of the *** to moderate elevation of the liver enzymes are also common,although no case of acute liver failure has been reported so *** of the medications used for treatment of COVID-19 can also be associated with GI symptoms or liver injury and can be included in the differential diagnosis in these *** the diagnosis of the infection is currently based on RNA analysis in respiratory samples,the available literature on fecal shedding of this virus suggests that fecal RNA testing might prove to be a useful diagnostic *** is reasonable to delay all non-urgent endoscopic procedures during the peak of the pandemic and use additional protective equipment such as N95 respirators during endoscopy while most patients can be considered high risk for having been exposed to the virus.

关键词： SARS-CoV-2 COVID-19 Gastroenterology Hepatology Liver

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