检索结果-南通市图书馆

Influence of Different Sterilization Conditions on the Growth and Exopolysaccharide of Streptococcus thermophilusand Co-Cultivation with Lactobacillus delbrueckiisubsp. bulgaricusOLL1073R-1

引用

Advances in Microbiology 2015年第11期5卷 760-767页

作者： Junko Nishimura Seiya Makino katsunori kimura Emiko Isogai Tadao Saito Laboratory of Nutrition and Life Sciences Department of Biotechnology and Environmental Engineering Faculty of Engineering Hachinohe Institute of Technology Hachinohe Japan Laboratory of Animal Products Chemistry Graduate School of Agricultural Science Tohoku University Sendai Japan Food Science Research Labs. Meiji Co. Ltd. Odawara Japan Laboratory of Animal Microbiology Graduate School of Agricultural Science Tohoku University Sendai Japan

The sterilization conditions between experiment and dairy industrial level are different and concern about influence on product’s qualities. In this study, the fermentation properties of Streptococcus thermophilus, alone and in combination with Lactobacillus delbrueckii subsp. bulgaricus, were evaluated in skim milk that had been subjected to distinct sterilization conditions. Growth, organic acid generation, and EPS production were determined using pasteurized or autoclaved milk. When S. thermophilus was cultivated in pasteurized skim milk, the growth was strain-dependent. On the other hand, growth of S. thermophilus was accelerated in autoclaved milk. Exocellular polysaccharide (EPS) production by L. bulgaricus was not affected by the combination of S. thermophilus strains. Thus, we observed that yogurt fermented by L. bulgaricus was minimally affected by the combination of S. thermophilus strains;growth of L. bulgaricus was maintained under the constant environment. These results should facilitate the development of fermented milk produced from L. bulgaricus in the dairy industry.

关键词： Streptococcus thermophilus Lactobacillus delbrueckii subsp. bulgaricus Sterilization Formic Acid Exopolysaccharide

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of water saturation and loading rate on direct shear tests of andesite

引用

Journal of Rock Mechanics and Geotechnical Engineering 2022年第2期14卷 653-662页

作者： Tianshu Bao Kimihiro Hashiba katsunori Fukui Department of Systems Innovation The University of TokyoTokyo113-8656Japan

For estimating the long-term stability of underground framework,it is vital to learn the mechanical and rheological characteristics of rock in multiple water saturation ***,the majority of previous studies explored the rheological properties of rock in air-dried and water saturated conditions,as well as the water effects on compressive and tensile *** this study,andesite was subjected to direct shear tests under five water saturation conditions,which were controlled by varying the wetting and drying *** tests were conducted at alternating displacement rates under three vertical *** results reveal that the shear strength decreases exponentially as water saturation increases,and that the increase in shear strength with a tenfold increase in displacement rate is nearly constant for each of the vertical *** on the findings of the shear tests in this study and the compression and tension tests in previous studies,the influences of both water saturation and loading rate on the Hoek-Brown failure criterion for the andesite was *** results indicate that the brittleness index of the andesite,which is defined as the ratio of uniaxial compressive strength to tensile strength,is independent of both water saturation and loading rate and that the influences of the water saturation dependence and the loading rate dependence of the failure criterion can be converted between each other.

关键词： Direct shear test Water saturation Loading rate dependence Failure criterion

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Geographic differences in low-dose aspirin-associated gastroduodenal mucosal injury

引用

World Journal of Gastroenterology 2015年第25期21卷 7709-7717页

作者： katsunori Iijima Tooru Shimosegawa Division of Gastro- enterology Tohoku University Graduate School of Medicine

Aspirin, even at low doses, has been known to cause upper gastro-intestinal complications, such as gastroduodenal ulcers, despite the definite benefits from its antithrombotic effects. Helicobacter pylori(H. pylori) is major pathogen responsible for gastroduodenal ulcerformation. There have been conflicting results about the potential interaction between these two ulcerogenic factors and the geographic areas involved. In Western countries, the prevalence of gastroduodenal ulcers is consistently higher in H. pylori-positive low-dose aspirin(LDA) users than in H. pylori-negative ones, suggesting that H. pylori infection exacerbates LDA-induced gastroduodenal mucosal injury in these geographic areas. Meanwhile, previous studies from Japan have generally reported a similar prevalence of LDA-induced gastroduodenal mucosal injury regardless of the presence of H. pylori infection, indicating that the infection is not an overall exacerbating factor for drug-induced injury. H. pylori infection could have a synergistic or antagonistic interaction with LDA use in adverse gastroduodenal events depending on gastric acid secretion. It is wellrecognized that the net effect of H. pylori infection on gastric acid secretion shows considerable geographic variation at the population level. While gastric acid secretion levels were not decreased and were wellpreserved in most patients with H. pylori infection from Western countries, the majority of Japanese patients with H. pylori infection exhibited decreased gastric acid secretion. Such large geographic differences in the net effect of H. pylori infection on gastric acid secretion could be at least partly responsible for the geographically distinct interaction between LDA use and H. pylori infection on adverse gastroduodenal lesions.

关键词： Helicobacter pylori Low-dose aspirin Gastricacid secretion Gastroduodenal ulcers Geographicvariation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

LESS-INVASIVE LASER THERAPY AND DIAGNOSIS USING A TABLETOP MID-INFRARED TUNABLE LASER

引用

Journal of Innovative Optical Health Sciences 2010年第4期3卷 285-292页

作者： HISANAO HAZAMA katsunori ISHII KUNIO AWAZU Graduate School of Engineering Osaka University 2-1 YamadaokaSuitaOsaka 565-0871Japan Research Institute of Nuclear Engineering University of Fukui 3-9-1 BunkyoFukuiFukui 910-8507Japan Institute for Chemical Research Kyoto University GokashoUjiKyoto 611-0011Japan

Since numerous characteristic absorption lines caused by molecular vibration exist in the midinfrared(MIR)wavelength region,selective excitation or selective dissociation of molecules is possible by tuning the laser wavelength to the characteristic absorption lines of target *** applying this feature to the medical fields,less-invasive treatment and non-destructive diagnosis with absorption spectroscopy are possible using tunable MIR lasers.A high-energy nanosecond pulsed MIR tunable laser was obtained with difference-frequency generation(DFG)between a Nd:YAG and a tunable Cr:forsterite *** MIR-DFG laser was tunable in a wavelength range of 5.5–10μm and generated laser pulses with energy of up to 1.4mJ,a pulse width of 5 ns,and a pulse repetition rate of 10 *** removal of atherosclerotic lesion was successfully demonstrated with the MIR-DFG laser tuned at a wavelength of 5.75μm,which corresponds to the characteristic absorption of the ester bond in cholesterol esters in the atherosclerotic *** have developed a non-destructive diagnostic probe with an attenuated total reflection(ATR)prism and two hollow optical *** absorption spectrum of cholesterol was measured with the ATR probe by scanning the wavelength of the MIR-DFG laser,and the spectrum was in good agreement with that measured with a commercial Fourier transform infrared spectrometer.

关键词： Mid-infrared tunable laser difference-frequency generation selective treatment attenuated total reflection spectroscopy hollow optical fiber

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Electron transmission and quantum current distribution of C_(70) molecule

引用

Science China(Physics,Mechanics & Astronomy) 2008年第2期51卷 126-132页

作者： katsunori Tagami3 MASARU Tsukada Nano Technology Research Centre 120-5 Waseda University

The characteristics of electron transmission through C70 molecule bridge in which two atomic chain leads are connected to long-axis carbon atoms are investigated theoretically by using tight-binding approach based on the Green's function with only one π orbital electron per carbon atom. Electron transmission through C70 molecule from the input to the output terminal is obtained. From the spectrum, the switching feature of the electron transmission through C70 is found, and the oscil-lation property based on the quantized level is explained. The quantum current distributions inside C70 molecule bridge are calculated and simulated by the quan-tum current density theory based on Fisher-Lee formula at the energy point E = -0.2 eV, where the transmission spectrum shows a peak. The maximum and the mini-mum bond quantum currents are presented, and the reason why the currents are distributed nonuniformly is explained by the phase difference of the atomic orbits. The result shows that the currents at each atomic site agree with Kirchhoff quan-tum current conservation law.

关键词： C70 molecule electron transmission quantum current distribution

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Discovery and application of 6π-azaelectrocyclization to natural product synthesis and synthetic biology

引用

Science China Chemistry 2012年第1期55卷 19-30页

作者： TANAKA katsunori KATSUMURA Shigeo FUKASE Koichi Department of Chemistry Graduate School of ScienceOsaka University1-1 Machikaneyama Department of Chemistry and Open Research Center on Organic Tool Molecules School of Science and TechnologyKwansei Gakuin University

While elucidating the inhibitory mechanism of a hydrolytic enzyme by aldehyde-containing natural product,we discovered a reaction involving a rapid 6π-azaelectrocyclization of azatrienes generated from aldehyde with lysine *** electrocyclic reaction of the 1-azatriene system,a cyclization precursor,exhibited a significant substituent *** chiral piperidine synthesis and a one-pot library synthesis of pyridines on solid-supports were applied to synthesize pyridine/indole alkaloid-type natural ***,we developed lysine-based labeling and engineering of biomolecules and living cells based on the rapid 6π-*** labels and oligosaccharide structures were introduced efficiently and selectively into surface lysines under the mild conditions;notable effects of N-glycans on proteins and living cells were visualized for the first time by PET and noninvasive fluorescence imaging.

关键词： 6π-azaelectrocyclization enzyme inhibition lysine natural product synthesis synthetic biology labeling chemical engineering living cells N-glycan in vivo imaging tumor targeting

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Gastric carditis:Is it a histological response to high concentrations of luminal nitric oxide?

引用

World Journal of Gastroenterology 2006年第36期12卷 5767-5771页

作者： katsunori Iijima Tooru Shimosegawa Division of Gastroenter-ology Tohoku University Graduate School of Medicine Sendai Miyagi Japan

During the last decade, inflammation (carditis) and in- testinal metaplasia localized to immediately below the human gastro-oesophageal junction have received much attention in relation to the rising incidence of cancer at this site. Since these histological findings are frequently observed even among those who are H pylori-negative, the causative factors for such histologic events at the human gastro-oesophageal junction remain obscure. A series of recent studies have demonstrated that a high level of salivary nitrite is sustained over several hours after the ingestion of a high nitrate meal, and that the nitrite in swallowed saliva is rapidly converted to nitric oxide by an acid catalyzed chemical reaction at the gastro-oesophageal junction. Eventually, a substantial amount of nitric oxide diffuses from the lumen into the adjacent tissue. Therefore, the human gastro-oesopha- geal junction is likely to be a region of high nitrosative stress. Considering the life-time exposure of the gastro- oesophageal junction to cytotoxic levels of nitric oxide, this may account for the high prevalence of inflamma- tion, intestinal metaplasia, and subsequent development of neoplasia at this site. Although gastric acid, pepsin, and bile acid have been intensively investigated as a cause of adenocarcinoma at the gastro-oesophageal junction and the distal esophagus, nitric oxide and the related nitrosative stress should also be examined.

关键词： Nitric oxide Gastro-oesophageal junction Dietary nitrate Carditis Intestinal metaplasia at gastro-oesophageal junction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Physicochemical characterization of forest and sugarcane leaf combustion’s particulate matters using electron microscopy,EDS,XRD and TGA

引用

Journal of Environmental Sciences 2021年第1期33卷 296-310页

作者： Hay Mon Oo Preechar Karin Nuwong Chollacoop katsunori Hanamura Faculty of Engineering King Mongkut's Institute of Technology LadkrabangBangkok 10520Thailand National Metal and Materials Technology Center National Science and Technology Development AgencyPathum Thani 12120Thailand School of Engineering Tokyo Institute of TechnologyTokyo 152-8552Japan

Physical characteristics and quantitative elemental composition of PM and residual ash produced from sugarcane leaves(SCL)combustion were investigated using TEM-EDS compared with forest leaves(FRL).SEM-EDS was used to analyze the microstructure and chemical composition of biomass raw leaves and *** analysis was also performed to investigate the characterization of the crystalline nanostructure,structure of PM,and residual ash compared to the TEM image processing *** oxidation kinetics of biomass raw materials,PM,and residual ash were investigated by *** morphology of fine and ultrafine agglomerate structure of SCL soot and residual ash are not significantly different from the FRL soot and residual *** average diameter sizes of single primary nanoparticles of SCL and FRL soot are approximately 37 nm and 35 nm,while the sizes of residual ash are about 18 nm and 22 nm,*** single primary nanoparticles of soot are mainly composed of curve line crystallites of carbon fringes,while residual ash is composed of straightline lattice *** average fringe lengths of SCL and FRL soot are about 1.25 nm and 1.04 nm from the outer shell and 0.89 nm and 0.74 nm from the inner *** interlayer spacing of curve line carbon fringes of SCL and FRL soot is approximately 0.359 nm and 0.362 nm by the TEM image analysis and it was matched with XRD *** biomass PMs are mainly composed of soot,Si,Ca,and K compounds:SiO_(2),CaCO3,and KCl.

关键词： Biomass combustion Particulate matter Soot Ashes TEM XRD TGA

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pathogenesis and risk factors for gastric cancer after Helicobacter pylori eradication

引用

World Journal of Gastrointestinal Oncology 2016年第9期8卷 663-672页

作者： Reina Ohba katsunori Iijima Department of Gastroenterology Akita University Graduate School of Medicine

Helicobacter pylori(***) infection was thought to be the main cause of gastric cancer,and its eradication showed improvement in gastric inflammation and dec-reased the risk of gastric ***,a number of studies reported the occurrence of gastric cancer after successful *** infected with ***,even after eradication,have a higher risk for the occurrence of gastric cancer when compared with uninfected *** gastric cancer occurs frequently following the endoscopic removal of early gastric *** data indicate that metachronous cancer leads to the occurrence of gastric cancer even after successful eradication of *** pathogenesis of this metachronous cancer remains *** research is needed to identify biomarkers to predict the development of metachronous gastric cancer and methods for gastric cancer *** this article,we review the role of the *** in carcinogenesis and the histological and endoscopic characteristics and risk factors for metachronous gastric cancer after ***,we discuss recent risk predictions and possible approaches for reducing the risk of metachro-nous gastric cancer after eradication.

关键词： Helicobacter pylori Eradication Atrophic gastritis Intestinal metaplasia Metachronous gastric cancer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Gender difference in gastro-esophageal reflux diseases

引用

World Journal of Gastroenterology 2016年第5期22卷 1800-1810页

作者： kiyotaka asanuma katsunori iijima tooru shimosegawa Division of Gastroenterology Tohoku University Graduate School of MedicineMiyagi Prefecture 980-8574Japan

The incidence of esophageal adenocarcinoma(EAC) has risen sharply in western countries over the past 4 decades. This type of cancer is considered to follow a transitional process that goes from gastro-esophageal reflux disease(GERD) to Barrett's esophagus(BE,a metaplastic condition of the distal esophagus), a precursor lesion and ultimately adenocarcinoma. This spectrum of GERD is strongly predominant in males due to an unidentified mechanism. Several epidemiologic studies have des cribed that the prevalence of GERD, BE and EAC in women is closely related to reproductive status, which suggests a possible association with the estrogen level. Recently, we revealed in an in vivo study that the inactivation of mast cells by the anti-inflammatory function of estrogen may account for the gender difference in the GERD spectrum. Other studies have described the contribution of female steroid hormones to the gender difference in these diseases. Estrogen is reported to modulate the metabolism of fat, and obesity is a main risk factor of GERDs. Moreover, estrogen could confer esophageal epithelial resistance to causative refluxate. These functions of estrogen might explain the approximately 20-year delay in the incidence of BE and the subsequent development of EAC in women compared to men, and this effect may be responsible for the male predominance. However, some observational studies demonstrated that hormone replacement therapy exerts controversial effects in GERD patients. Nevertheless, the estrogen-related endocrine milieu may prevent disease progression toward carcinogenesis in GERD patients. The development of innovative alternatives to conventional acid suppressors may become possible by clarifying the mechanisms of estrogen.

关键词： gastro-esophageal reflux disease Barrett'sesophagus esophageal adenocarcinoma estrogen malepredominance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：