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A Patient with Intravenous Immunoglobulin-Responsive Lower Motor Neuron Syndrome

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International Journal of Clinical Medicine 2012年第3期3卷 190-193页

作者： Takaomi Kessoku Takashi Koide katsunori Akiyama Sachiko Irie Tadayuki Ishihara Fumihito Yoshii 2Department of Neurology Hiratsuka City Hospital Hiratsuka Japan Department of Internal Medicine Hiratsuka City Hospital Hiratsuka Japan Department of Neurology Hiratsuka City Hospital Hiratsuka Japan Department of Neurology Kitasato University School of Medicine Sagamihara Japan Department of Neurology National Hakone Hospital Odawara Japan Department of Neurology Tokai University School of Medicine Isehara Japan

We report a 50-year-old woman who developed localized proximal muscle weakness, in addition to transient elevation of antibodies to GM-1 ganglioside, without multifocal conduction block. She was treated with intravenous immunoglobulin (IVIg) and steroid pulse therapy, which were effective for over 10 years. Her clinical course and laboratory tests were consistent with lower motor neuron syndrome (LMNS) with localized proximal muscle weakness. We suggest that some patients diagnosed as LMNS may remain responsive to IVIg or steroid pulse therapy for a long time.

关键词： Lower Motor Neuron Syndrome (LMNS) Multifocal Motor Neuropathy (MMN) Localized Proximal Muscle Weakness Intravenous Immunoglobulin (IVIg) Anti-GM1 Ganglioside Antibody

A Novel Transglutaminase From Bacillus subtilis Spores

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A Novel Transglutaminase From Bacillus subtilis Spores

Outcomes and Prognostic Factors for Adenocarcinoma/Adenosquamous Carcinomas Treated with Radical Hysterectomy and Adjuvant Therapy

The Eighth China-Japan-Korea Joint Symposium on Enzyme Engineering

作者： Kenzo Yokozeki Shunich Suzuki katsunori Kobayashi Shigeru Yamanaka Yuzuru Eto AminoScience Laboratories Global Foods ＆ Amino Acids CompanyAjinomoto Co.Inc.

＜正＞（Introduction）Transglutaminase（TGase;EC 2.***.2.13）is an acyltransferase that catalyzes cross-linking reactions between theγ-carboxyamide groups of glutamine residues in proteins and primary amine groups of v...

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Open Journal of Obstetrics and Gynecology 2014年第14期4卷 909-915页

作者： Masayuki Yamaguchi Yoko Yamagishi Nobumichi Nishikawa Masayuki Sekine Takehiro Serikawa katsunori Kashima Takayuki Enomoto Department of Obstetrics and Gynecology Graduate School of Medical and Dental Sciences Niigata University Niigata City Japan

Objective: To determine outcomes and prognostic factors for early-stage cervical adenocarcinoma/ adenosquamous carcinomas (AC/ASC) patients who are treated with radical hysterectomy and adjuvant therapy to optimize their treatment. Methods: We retrospectively reviewed the medical records of 26 patients with International Federation of Gynecologists and Obstetricians stage IB-IIB cervical AC/ASC who were treated with radical hysterectomy and adjuvant therapy. Overall survival (OS) and progression-free survival (PFS) were calculated using the Kaplan-Meier method and compared using the log-rank test. The prognostic significance of various clinical features was determined by using multivariate analysis with the Cox proportional hazards regression model. Results: Univariate analysis revealed that OS was significantly shorter in patients with lymph node metastasis and lymphovascular space invasion. Similarly, PFS was significantly shorter for patients with lymph node metastasis and parametrial invasion. Furthermore, multivariate analysis showed that lymph node metastasis was the only independent predictor for PFS (hazard ratio: 6.47, 95% confidence interval: 1.33 - 31.44, p = 0.021). However, the use of adjuvant chemoradiotherapy did not have any significant effect on either OS or PFS, regardless of lymph node metastasis. Conclusions: Lymph node metastasis is an independent prognostic factor for poor survival in cervical AC/ASC patients treated with radical hysterectomy and adjuvant therapy. In addition, adjuvant chemoradiotherapy does not improve their survival, regardless of lymph node metastasis, which suggests that novel or personalized adjuvant therapeutic strategies with fewer adverse effects than existing strategies are needed.

关键词： Adjuvant Therapy Cervical Adenocarcinoma Cervical Adenosquamous Carcinoma Lymph Node Metastasis Prognostic Factors

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利用近红外彩色成像技术监测松萎蔫病

南京林业大学学报（自然科学版） 2011年第4期35卷 150-151页

作者： katsunori Nakamura Mamoru Takehana Tsuneo Itagaki Hayato Tashiro Kazumasa Ohta Osamu Nakakita Tohoku Research Center Forestry and Forest Products Research Institute Morioka Iwate 020-0123 Japan

有效监测患病株方法的缺失是导致对松萎蔫病难以成功控制的主要原因之一。利用航空手段调查该病导致的针叶颜色变化已被证明是一种可靠的方法。为了克服该方法固有的缺点,笔者引用了近红外彩色胶片航拍方法。该项技术在获得正摄航拍图像... 详细信息

有效监测患病株方法的缺失是导致对松萎蔫病难以成功控制的主要原因之一。利用航空手段调查该病导致的针叶颜色变化已被证明是一种可靠的方法。为了克服该方法固有的缺点,笔者引用了近红外彩色胶片航拍方法。该项技术在获得正摄航拍图像时,通过图像处理可以增强松针颜色变化,获得较直接拍摄图像更明显的色差。因为图像可以在室内仔细处理,因此能解决飞行时间缺乏等问题。但是,该方法也存在对被压木无法获得其影像而漏检的缺陷。笔者研发的计算机软件可以将目标树标记在计算机图像文件上,并且标记树的地理位置数据和背景航拍图像并传输到装有内置GPS接收器的掌上电脑中,借助软件产生的图像导航定位系统,有利于地面接近标记树,从而可以现场检查和校正标记树的数据,并将修正数据传回至主机。此方法利用最新航拍图像技术建立对每株树处理和管理的连续资料,大大改善了防控松萎蔫病的措施。

关键词：松萎蔫病红外航空图像地理信息系统监测

世界上首次使用在日本发电站的500kV交联聚乙烯绝缘铝护套电力电缆

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电线电缆 1991年第5期 21-26页

作者： katsunori Ogawa 周汉亮

1988年,在日本电力开发公司(EPDC)所属的 Shimogo 发电站和东京电力公司(TEPO)的 Imaichi 发电站,采用了500 kV 交联聚乙烯绝缘(XLPE)铝护套电力电缆,这是国际上首次实际应用。自1983年以来,对该产品进行了开发研究工作。在质量控制上... 详细信息

1988年,在日本电力开发公司(EPDC)所属的 Shimogo 发电站和东京电力公司(TEPO)的 Imaichi 发电站,采用了500 kV 交联聚乙烯绝缘(XLPE)铝护套电力电缆,这是国际上首次实际应用。自1983年以来,对该产品进行了开发研究工作。在质量控制上精心研究,从而消除了绝缘中杂质,并在整个挤出长度上及较厚绝缘中消除了各种缺陷。在上述两发电站中成功地完成了敷设及安装工作,目前正处于良好运行中。

关键词：电力电缆铝护套发电厂日本

Cerebral Infarction after Spine Surgery: Report of Two Cases

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Open Journal of Orthopedics 2013年第4期3卷 204-207页

作者： katsunori Fukutake Hiroshi Takahashi Yuichiro Yokoyma Yasuaki Iida Ryo Takamatsu Kazumasa Nakamura Akihito Wada Department of Orthopaedic Surgery Toho University School of Medicine Tokyo Japan Department of Orthopaedic Surgery Toho University School of Medicine Tokyo Japan.

There has been an increase in spinal surgery for the elderly, with a corresponding potential increase in perioperative complications. In our department, 1833 patients underwent spinal surgery under general anesthesia from April 2001 to October 2012, and 2 of 260 patients aged ≥75 years old had postoperative cerebral infarction. An analysis of the pathogenic mechanism and potential risk factors showed that a history of cerebral infarction was a significant risk factor. Blood pressure rapidly increased on arousal from anesthesia, and particularly on extubation. The change in blood pressure was examined as a potential risk factor for cerebral infarction, but no significant relationship was observed. This result requires further examination in more patients with cerebral infarction after spinal surgery.

关键词： Cerebral infarction Spine surgery Complication

A Case of Septic Arthritis of the Shoulder Joint That Developed after Suprascapular Nerve Block

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Open Journal of Orthopedics 2020年第2期10卷 25-32页

作者： Taihei Go Toshiyuki Tsutsui Yasuaki Iida katsunori Fukutake Ryoichi Fukano Kosei Ishigaki Masayuki Sekiguchi Hiroshi Takahashi Department of Orthopedics Toho University Tokyo Japan Department of Orthopedics Sagamihara Chuo Hospital Kanagawa Japan Department of Orthopedics Omori Red Cross Hospital Tokyo Japan Department of Orthopedics Japan Community Health Care Organization Tokyo Kamata Medical Center Tokyo Japan

Septic arthritis of the shoulder is uncommon in the immunocompetent patient with no previous risk factors for joint infection. We treated an immunocompetent patient who developed septic arthritis of the shoulder after suprascapular nerve block for pain due to rotator cuff tear. An 80-year-old man with no underlying disease visited a nearby orthopedics clinic with complaint of left shoulder joint pain. Left suprascapular nerve block was performed, but the pain gradually aggravated. On the day after the block, he had a fever of 39°C and came to our department. On examination, enlargement and tenderness were present at the injection site. Cellulitis at the site was suspected. He was admitted and administration of a cephem anti-biotic was started. Pain subsequently decreased. Magnetic resonance imaging (MRI) performed 4 days after hospitalization showed massive effusion close to the injection site. The effusion spread into the joint cavity through the tear site of the supraspinatus. Septic arthritis of the shoulder was strongly suspected, open irrigation and debridement were performed 11 days after hospitalization. After surgery, pain immediately improved. In our case the extra-articular infection caused by suprascapular nerve block considered to spread into the shoulder joint cavity through the site of rotator cuff tear, although there have been no reports of such cases. This case suggests the possibility that patients with rotator cuff tear may easily develop septic arthritis because extra-articular infection may spread into the joint cavity through the site of tear.

关键词： Septic Arthritis of the Shoulder Joint Suprascapular Nerve Block Rotator Cuff Tear

The Number of Positive Tumor Marker Status Is Beneficial for the Selection of Therapeutic Modalities in Patients with Hepatocellular Carcinoma

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Journal of Clinical and Translational Hepatology 2017年第2期5卷 165-168页

作者： Toru Beppu Shigeki Nakagawa Hidetoshi Nitta Hirohisa Okabe Takayoshi Kaida katsunori Imai Hiromitsu Hayashi Yuki Koga Kunitaka Kuramoto Daisuke Hashimoto Yo-ichi Yamashita Akira Chikamoto Takatoshi Ishiko Hideo Baba Department of Surgery Yamaga City Medical Center Kumamoto Japan Department of Gastroenterological Surgery Graduate School of Life Sciences Kumamoto University Kumamoto Japan Department of Gastroenterological Surgery Graduate School of Life Sciences Kumamoto University Kumamoto Japan

Hepatic resection (HR) and radiofrequency ablation (RFA) are popular local therapies for early-stage hepatocellular carcinoma (HCC).Alpha-fetoprotein,Lens culinaris agglutininreactive fraction of alpha-fetoprotein,and des-c-carboxy prothrombin are well-known and useful tumor markers for *** positive number status of these tumor markers has recently been demonstrated as beneficial for predicting outcome for HCC patients treated with local *** the normal ranges reported have differed by institution,the positivity of tumor markers is consistent and can easily be *** and Wakayama's group clearly demonstrated the following:1) Regardless of the degree of tumor stage,a triple-positive tumor marker profile can predict poor outcome in HCC patients undergoing HR;2) For RFA alone,HCC patients with double-and triple-positive status,having less than three lesions and lesions ≤3 cm in diameter show comparably insufficient outcomes;3) For HCC patients with lesions ≤5 cm in Child-Pugh grade A,HR is preferred over RFA;4) Microvascular invasion rates increased even in the double-positive patients,while poorly differentiated HCC was frequently observed only in the triple-positive patients;and 5) RFA with chemoembolization,anatomical liver resection,and postoperative adjuvant chemoembolization or hepatic arterial chemotherapy might improve the outcome for patients with highly malignant HCC with multiple positive tumor ***,the impacts of these therapies still need to be evaluated in prospective comparative studies.

关键词： Triple-positive tumor markers Double-positive tumor markers Hepatocellular carcinoma Hepatic resection Radiofrequency ablation Alpha-fetoprotein Des-γ-carboxy prothrombin Lens culinaris agglutinin reactive fraction of alpha-fetoprotein

Decomposition of Poly（Amide-imide）Film Enameled on Solid Copper Wire by ATMOSPHERIC Pressure Non-Equilibrium Plasma

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Decomposition of Poly（Amide-imide）Film Enameled on Solid C...