检索结果-南通市图书馆

Lightwave Modulation Techniques for Advanced Modulation Formats

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Communications 2010年第3期7卷 35-42页

作者： Tetsuya kawanishi National Institute of Information and Communications Technology (NICT)

Arbitrary waveform can be synthesized by two orthogonal components: in-phase and quadrature components. Thus, if we can manipulate the two components independently, various complicated modulation can be achieved. This technique is called vector modulation, which is commonly used in wireless radio communication systems where the carrier frequency is lower than 100GHz. On the other hand, in lightwave transmission systems, the carrier frequency is higher than 100THz, and the stability of the signal sources would be much poorer than in radio systems, so that the simplest modulation format (on-off-keying) was often used in commercial systems. However, recently, various modulation techniques such as quadrature amplitude modulation, etc., have been demonstrated by using precise and rapid lightwave control. In this report, we review recent progress in optical vector modulation technologies which can generate highspeed and complicated optical signals. Integrated optical modulators can synthesize multi-level signals in photonic circuits.

关键词： vector modulation integrated optical modulator photonic circuit

An EMG-Based Biomimetic Variable Stiffness Modulation Strategy for Bilateral Motor Skills Relearning of Upper Limb Elbow Joint Rehabilitation

在线全文

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2023年第4期20卷 1597-1612页

作者： Ziyi Yang Shuxiang Guo Keisuke Suzuki Yi Liu Masahiko kawanishi Graduate School of Engineering Kagawa UniversityTakamatsuKagawa761-0396Japan Key Laboratory of Convergence Medical Engineering System and Healthcare Technology School of Life Science and TechnologyBeijing Institute of TechnologyBeijing100081China National Rehabilitation Center for Persons with Disabilities Tokorozawa359-8555Japan Faculty of Medicine Kagawa UniversityTakamatsuKagawa761-0793Japan

Bilateral rehabilitation systems with bilateral or unilateral assistive robots have been developed for hemiplegia patients to recover their one-side ***,the compliant robotic assistance to promote bilateral inter-limb coordination remains a challenge that should be *** this paper,a biomimetic variable stiffness modulation strategy for the Variable Stiffness Actuator(VSA)integrated robotic is proposed to improve bilateral limb coordination and promote bilateral motor skills *** Electromyography(EMG)-driven synergy reference stiffness estimation model of the upper limb elbow joint is developed to reproduce the muscle synergy effect on the affected side limb by independent real-time stiffness ***,the bilateral impedance control is incorporated for realizing compliant patient-robot *** experiments were carried out to evaluate the tracking performance and investigate the multiple task intensities’influence on bilateral motor skills *** results evidence the proposed method could enable bilateral motor task skills relearning with wide-range task intensities and further promote bilateral inter-limb coordination.

关键词： Biomimetic stiffness modulation Compliant physical human-robot interaction(pHRI) Electromyography(EMG) Variable stiffness actuator(VSA) Rehabilitation robotics Synergy-based control Skill relearning

Numerical Analysis of Electrically Tunable Delay-Line with an SSB Modulator

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

光学学报 2003年第S1期23卷 619-620页

作者： Tetsuya kawanishi Masayuki Izutsu Communications Research Laboratory 4-2-1 Nukui-kita Koganei Tokyo 184-8795 JapanCommunications Research Laboratory 4-2-1 Nukui-kita Koganei Tokyo 184-8795 Japan

By using an optical system simulator, we investigated the tunable delay-line with an optical SSB modulator and an optical fiber loop, where the delay can be controlled by the electric signal fed to the modulator.

关键词： SSB be of Numerical Analysis of Electrically Tunable Delay-Line with an SSB Modulator were FBG line into with

High Spatial Resolution Electro -Optic Field -Mapping for Three Orthogonal Field Components in a Micro -Structured Electrode

在线全文

学校读者我要写书评

暂无评论

光学学报 2003年第S1期23卷 831-832页

作者： Yoshiro Matsuo Tetsuya kawanishi Satoshi Oikawa Kaoru Higuma Masayuki Izutsu Basic and advanced research division Communications Research Laboratory 4-2-1 Nukui-kitamachi Koganei Tokyo 184-8795 Japan New technology laboratory Sumitomo-Osaka Cement Co. Ltd 585 Toyotomi-cho Funabashi Chiba 274-8601 Japan

The optically based technique of electro-optic (EO) sampling has been used for diagnosing the internal high-speed signals of integrated *** of the features that make the EO sampling technique very promising is a minimal probe: the EO sampling technique does not require an electrode and ground plane incorporated as part of a probe so that, compared with conventional metal probes, the invasiveness of an EO probe is minimal.

关键词： sampling technique integrated circuits

Low Loss Polarization Maintaining Photonic Crystal Fiber

在线全文

学校读者我要写书评

暂无评论

光学学报 2003年第S1期23卷 31-32页

作者： Masatoshi Tanaka Osamu Tohyama Syun-ichiro Yamaguchi Hirokazu Kubota Satoki kawanishi Mitsubishi Cable Industries LTD4-3 IkejiriItamiHyogoJapanMitsubishi Cable IndustriesLTD4-3 IkejiriItamiHyogoJapanMitsubishi Cable IndustriesLTD4-3 IkejiriItamiHyogoJapanNTT Network Innovation LaboratoriesNTTCorporation1-1Hikarino-okaYokosukaJapanNTT Network Innovation LaboratoriesNTTCorporation1-1Hikarino-okaYokosukaJapan

A low loss polarization maintaining photonic crystal fiber has been fabricated. The fiber loss was 1.3 dB/km at 1550 nm. The polarization crosstalk for a 100-m fiber was -35 dB at 1550 nm.

关键词： PCF of on nm in as Low Loss Polarization Maintaining Photonic Crystal Fiber 双加 PM for

Longitudinal observation of ten family members with idiopathic basal ganglia calcification: A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2019年第12期7卷 1483-1491页

作者： Seiju Kobayashi Kumiko Utsumi Masaru Tateno Tomo Iwamoto Tomonori Murayama Hitoshi Sohma Wataru Ukai Eri Hashimoto Chiaki kawanishi Shinyukai Nakae Hospital Sapporo 0010022 Japan Department of Neuropsychiatry Sapporo Medical University Graduate School of Medicine Sapporo 0608543 Japan Department of Psychiatry Sunagawa City Medical Center Sunagawa 0730196 Japan Tokiwa Child Development Center Tokiwa Hospital Sapporo Japan Department of Neuropsychiatry Sapporo Medical University Graduate School of Medicine Sapporo 0050853 Japan Department of Educational Development Sapporo Medical University Center for Medical Education Sapporo 0608543 Japan Department of Biomedical Engineering Sapporo Medical University School of Medicine Sapporo 0608543 Japan

BACKGROUND Familial idiopathic basal ganglia calcification (FIBGC) is a rare autosomal dominant disorder that causes bilateral calcification of the basal ganglia and/or cerebellar dentate nucleus, among other locations. CASE SUMMARY The aim of this study is to report 10 cases of FIBGC observed in a single family. Seven patients showed calcification on their computed tomography scan, and all of these patients carried the SLC20A2 mutation. However, individuals without the mutation did not show calcification. Three patients among the 7 with calcification were symptomatic, while the remaining 4 patients were asymptomatic. Additionally, we longitudinally observed 10 subjects for ten years. In this paper, we mainly focus on the clinical course and neuroradiological findings in the proband and her *** The accumulation of more case reports and further studies related to the manifestation of FIBGC are needed.

关键词： Idiopathic basal ganglia calcification Fahr’s disease SLC20A2 Diffuse neurofibrillary tangles with calcification Single-photon emission computed tomography Case report

Predicting the distribution of the Asian tapir in Peninsular Malaysia using maximum entropy modeling

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Integrative Zoology 2012年第4期7卷 400-406页

作者： Gopalasamy Reuben CLEMENTS D.Mark RAYAN Sheema Abdul AZIZ Kae kawanishi Carl TRAEHOLT David MAGINTAN Muhammad Fadlli Abdul YAZI Reid TINGLEY Center for Tropical Environmental and Sustainability Science and School of Marine and Tropical Biology James Cook UniversityCairnsAustralia Center for Malaysian Indigenous Studies University of MalayaKuala LumpurMalaysia WWF Malaysia Petaling JayaMalaysia Durrell Institute of Conservation and Ecology University of KentCanterburyUK Malaysian Conservation Alliance for Tigers(MYCAT)Secretariat's Office Petaling JayaMalaysia Copenhagen Zoo CopenhagenDenmark Department of Wldife and National Parks Peninsular Malaysia Kuala LumpurMalaysia School of Biological Sciences University of SydneySydneyAustralia

In 2008,the IUCN threat status of the Asian tapir(Tapirus indicus)was reclasified from‘vulnerable'to‘en-dangered'.The latest distribution map from the IUCN Red List suggests that the tapirs'native range is becom-ing increasingly fragmented in Peninsular Malaysia,but distribution data collected by local researchers sug-gest a more extensive geographical ***,we compile a database of 1261 tapir occurrence records within Peninsular Malaysia,and demonstrate that this species,indeed,has a much broader geographical range than the IUCN range map ***,extreme spatial and temporal bias in these records limits their utility for conservation ***,we used maximum entropy(MaxEnt)modeling to elucidate the potential ex-tent of the Asian tapir's occurrence in Peninsular Malaysia while accounting for bias in existing distribution *** MaxEnt model predicted that the Asian tapir has a wider geographic range than our fine-scale data and the IUCN range map both *** 37%of Peninsular Malaysia contains potentially suit-able tapir *** results justify a revision to the Asian tapir's extent of occurrence in the IUCN Red ***,our modeling demonstrated that selectively logged forests encompass 45%of potentially suitable tapir habitats,underscoring the importance of these habitats for the conservation of this species in Peninsular Malaysia.

关键词： ecological niche IUCN Malayan tapir mammal MaxEnt species distribution model

Targeting fructose metabolism by glucose transporter 5 regulation in human cholangiocarcinoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genes & Diseases 2022年第6期9卷 1727-1741页

作者： Nattawan Suwannakul Napat Armartmuntree Raynoo Thanan Kaoru Midorikawa Tetsuo Kon Shinji Oikawa Hatasu Kobayashi Ning Ma Shosuke kawanishi Mariko Murata Department of Environmental and Molecular Medicine Mie University Graduate School of MedicineTsuMie 514-8507Japan Department of Biochemistry Faculty of MedicineKhon Kaen UniversityKhon Kaen 40002Thailand Laboratory of Functional Genomics Graduate School of BioscienceNagahama Institute of Bioscience and TechnologyNagahamaShiga 526-0829Japan Graduate School of Health Science Suzuka University of Medical ScienceSuzukaMie 513-8670Japan Faculty of Pharmaceutical Sciences Suzuka University of Medical ScienceSuzukaMie 513-8670Japan

Alterations in cellular metabolism may contribute to tumor proliferation and *** of the facilitative glucose transporter(GLUT)plays a key role in promoting ***5 mediates modulation of fructose utilization,and its overexpression has been associated with poor prognosis in several ***,its metabolic regulation remains poorly ***,we demonstrated elevated GLUT5 expression in human cholangiocarcinoma(CCA),using RNA sequencing data from samples of human tissues and cell lines,as compared to normal liver tissues or a cholangiocyte cell *** exhibiting highexpression of GLUT5 showed increased rates of cell proliferation and ATP production,particularly in a fructose-supplemented *** contrast,GLUT5 silencing attenuated cell proliferation,ATP production,cell migration/invasion,and improved epithelialemesenchymal transition(EMT)***,fructose consumption increased tumor growth in a nude mouse xenograft model,and GLUT5 silencing suppressed growth,supporting the tumor-inhibitory effect of GLUT5 ***,in the metabolic pathways of fructolysis-Warburg effect,the expression levels of relative downstream genes,including ketohexokinase(KHK),aldolase B(ALDOB),lactate dehydrogenase A(LDHA),and monocarboxylate transporter 4(MCT4),as well as hypoxia-inducible factor 1 alpha(HIF1A),were altered in a GLUT5 expression-dependent *** together,these findings indicate that GLUT5 could be a potential target for CCA therapeutic approach via metabolic regulation.

关键词： Cholangiocarcinoma Fructose Glucose transporter 5 Metabolic regulation Warburg effect

Nitrative and oxidative DNA damage in intrahepatic cholangiocarcinoma patients in relation to tumor invasion

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2005年第30期11卷 4644-4649页

作者： Somchai Pinlaor Banchob Sripa Ning Ma Yusuke Hiraku Puangrat Yongvanit Sopit Wongkham Chawalit Pairojkul Vajarabhongsa Bhudhisawasdi Shinji Oikawa Mariko Murata Reiji Semba Shosuke kawanishi Department of Parasitology Department of Pathology Department of Anatomy Department of Environmental and Molecular Medicine Department of Biochemistry Department of Surgery

AIM： Nitrative and oxidative DNA damage such as 8-nitroguanine and 8-oxo-7,8-dihydro-2＇-deoxyguanosine （8-oxodG） formation has been implicated in initiation and/ or promotion of inflammation-mediated carcinogenesis. The aim of this study is to clarify whether these DNA lesions participate in the progression of intrahepatic cholangiocarcinoma. METHODS： We investigated the relation of the formation of 8-nitroguanine and 8-oxodG and the expression of hypoxia-inducible factor-1α （HIF-1α） with tumor invasion in 37 patients with intra-hepatic cholangiocarcinoma. RESULTS： Immunohistochemical analyses revealed that 8-nitroguanine and 8-oxodG formation occurred to a much greater extent in cancerous tissues than in non-cancerous tissues. HIF-1α could be detected in cancerous tissues in all patients, suggesting low oxygen tension in the tumors. HIF-1α expression was correlated with inducible niltric oxide synthase （iNOS） expression （r = 0.369 and P = 0.025） and 8-oxodG formation （r = 0.398 and P = 0.015）. Double immunofluorescence study revealed that iNOS and HIF-1α co-localized in cancerous tissues. Notably, the formation of 8-oxodG was correlated significantly with lymphatic invasion （r = 0.386 and P = 0.018）. Moreover, 8- nitroguanine and 8-oxodG in non-cancerous tissues were associated significantly with neural invasion （P = 0.042 and P = 0.026, respectively）. These results suggest that reciprocal activation between HIF-1α and iNOS mediates persistent DNA damage, which induces tumor invasiveness via mutations, resulting in poor prognosis. CONCLUSION： The formation of 8-nitroguanine and 8-oxodG plays an important role in multiple steps of genetic changes leading to tumor progression, including invasiveness.

关键词： 8-Nitroguanine 8-Oxo-7,8-dihydro-2'-deoxyguanosine Hypoxia-inducible factor-1α Cholangiocarcinoma Tumor invasion