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Study on fibroin heavy chain of the silkworm Bombyx mori by fluorescence in situ hybridization (FISH)

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Science China(Life Sciences) 2002年第6期45卷 663-668页

作者：宋方洲张平波易发平洪锡钧鲁成 Yutaka Banno Hiroshi Fujii katsumi Koga College of Basic Medical Sciences Chongqing University of Medical Sciences Chongqing 400016 China Key Sericultural Laboratory of Agriculture Ministry Southwest Agricultural University Chongqing 400716 China Key Sericultural Laboratory of Agriculture Ministry Southwest Agricultural University Chongqing 400716 China School of Life Science Southwest China Normal University Chongqing 400715 China

The sericulture industry plays a very important role in our national economy. Silkworm (Bombyx mori) is always regarded as a model animal and biological reactor. There have been detailed studies on the structure, expression and control and molecular evolution of silk genes. However, few, if any, reports are available on the localization of structural genes in silkworm by molecular cytogenetics. The present experiment has tentatively localized the Fib-H gene at the distal end of the 25th linkage group, namely at the 25-0.0 position, and verified that Fib-H has only one locus, thus providing a temporary solution to the problem about its localization.

关键词： silkworm Bombyx mori, fibroin gene, fluorescence in situ hybridization, gene localization.

Development and Future Trends of Traditional Kampo Medicine in Japan

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Chinese Medicine and Culture 2022年第1期5卷 58-64页

作者： Risa shibata Gui-Xiang Chu Xun Lin Jin-Rong Fu Gynaecology Department of TCM Longhua Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 200032China International Office Shanghai University of Traditional Chinese MedicineShanghai 201203China

Traditional Kampo medicine is based on traditional Chinese medicine,which spread to Japan via the Korean Peninsula in the 5th *** practice of Kampo developed gradually under the influence of local Japanese culture and prospered until the Meiji *** appeared in schools successively,such as the School of Later Developments,the School of Classic Methods,the School of Textual Research,and the Integrated ***,the practice of Kampo gradually declined after the Meiji ***,through the continuous efforts of knowledgeable Japanese Kampo practitioners,the practice of Kampo has entered a new era as an indispensable aspect of contemporary Japanese medicine.

关键词： Medical history History Japan Kampo Traditional Chinese medicine

The ultra-low-frequency magnetic disturbances associated with earthquakes

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Earthquake Science 2011年第6期24卷 523-534页

作者： Masashi Hayakawa Yasuhide Hobara Kenji Ohta katsumi Hattori Advanced Wireless Communications Research Center The University of Electro-Communications1-5-1 ChofugaokaChofu Tokyo 182-8585Japan Research Station on Seismo Electromagnetics The University of Electro-Communications1-5-1 ChofugaokaChofu Tokyo 182-8585Japan Hayakawa Institute of Seismo Electromagnetics Co.Ltd.Incubation Center The University of Electro-Communications Chofu Tokyo182-8585Japan Information Systems Corp. Earthquake Analysis LaboratoryKita-Aoyama 2-14-42-305Minato-ku Tokyo 107-0061Japan Graduate School of Informatics and Engineering The University of Electro-CommunicationsChofu Tokyo 182-8585Japan Department of Electronic Information Chubu University1200 Matsumoto-choKasugai Aichi 487-8501Japan Faculty of Science Chiba University1-33 YayoiInage Chiba 263-8522Japan

The ultra-low-frequency （ULF） electromagnetic emission is recently recognized as one of the most promising candidates for short-term earthquake （EQ） prediction. This paper reviews previous convincing evidence on the presence of ULF emissions before three major EQs. Then, we present further statistical study on the ULF occurrence, our networks of ULF monitoring in different spatial scales in Japan and finally we present several signal processings to identify the seismogenic emissions by showing latest results for recent large EQs.

关键词： seismogenic ULF emission earthquake prediction magnetic sensor signal processing

Effect of branched-chain amino acids in patients receiving intervention for hepatocellular carcinoma

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World Journal of Gastroenterology 2014年第10期20卷 2673-2680页

作者： Tomoaki Ishihara Motoh Iwasa Hideaki Tanaka Masahiko Kaito Jiro Ikoma Toshiya shibata Yoshiyuki Takei Department of Gastroenterology and Hepatology Yokkaichi Digestive Disease Center Komono Mie 510-1232 Japan Department of Gastroenterology and Hepatology Mie University Graduate School of Medicine Tsu Mie 514-8507 Japan Department of Gastroenterology and Hepatology Mie Shokakinaika Tsu Mie 514-0062 Japan Department of Diagnostic Imaging and Nuclear Medicine Kyoto University Graduate School of MedicineKyoto 606-8507 Japan

AIM: To investigate the usefulness of branched-chain amino acids (BCAA) before transarterial chemoembolization (TACE) or radiofrequency ablation (RFA).

关键词： Branched-chain amino acids Cirrhosis Hepatocellular carcinoma Transarterial chemoembolization Radiofrequency ablation Hypoalbuminemia

Myocardial metastasis from ZEB1-and TWIST-positive spindle cell carcinoma of the esophagus:A case report

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World Journal of Gastroenterology 2024年第11期30卷 1636-1643页

作者： Yoshihiro shibata Hirofumi Ohmura Kazuki Komatsu Kosuke Sagara Atsuji Matsuyama Ryuji Nakano Eishi Baba Department of Medical Oncology Fukuoka Wajiro HospitalFukuoka 811-0213Japan Department of Oncology and Social Medicine Kyushu University Graduate School of Medical SciencesFukuoka 812-8582Japan Department of Pathology and Oncology University of Occupational and Environmental HealthKitakyushu 807-8555Japan Department of Diagnostic Pathology Fukuoka Wajiro HospitalFukuoka 811-0213Japan

BACKGROUND Metastatic cardiac tumors are known to occur more frequently than primary cardiac tumors,however,they often remain asymptomatic and are commonly dis-covered on *** tumors with a relatively high frequency of cardiac metastasis include mesothelioma,melanoma,lung cancer,and breast cancer,whereas reports of esophageal cancer with cardiac metastasis are *** SUMMARY The case of a 60-year-old man who complained of dysphagia is *** gastrointestinal endoscopy showed a submucosal tumor-like elevated lesion in the esophagus causing ***-enhanced computed tomography showed left atrial compression due to the esophageal tumor,multiple liver and lung metastases,and a left pleural *** examination of a biopsy speci-men from the esophageal tumor showed spindle-shaped cells,raising suspicion of esophageal *** disease progressed rapidly,and systemic chemotherapy was deemed necessary,however,due to his poor general condition,adminis-tration of cytotoxic agents was considered *** his high Combined Positive Score,nivolumab was administered,however,the patient soon died from the *** autopsy confirmed spindle cell carcinoma(SCC)of the esophagus and cardiac metastasis with similar histological *** stem cell markers,ZEB1 and TWIST,were positive in both the primary tumor and the cardiac *** To the best of our knowledge,there have been no prior reports of cardiac metastasis of esophageal *** case highlights our experience with a patient with esophageal SCC who progressed rapidly and died from the disease,with the autopsy examination showing cardiac metastasis.

关键词： Spindle cell carcinoma Esophagus Myocardial metastasis Epithelial-mesenchymal transition Case report

Micelle-crosslinked hydrogels with stretchable,self-healing,and selectively adhesive properties:Random copolymers work as dynamic yet self-sorting domains

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Aggregate 2023年第3期4卷 71-83页

作者： Hiroaki Asai Motoki shibata Mikihito Takenaka Shinichi Takata Kosuke Hiroi Makoto Ouchi Takaya Terashima Department of Polymer Chemistry Graduate School of EngineeringKyoto UniversityKatsuraKyotoJapan Office of Society-Academia Collaboration for Innovation Kyoto UniversityYoshida-honmachiKyotoJapan Institute for Chemical Research Kyoto UniversityUjiKyotoJapan RIKEN SPring-8 Center Sayo-choSayo-gunHyogoJapan J-PARC Center Japan Atomic Energy AgencyTokaiIbarakiJapan

The design of crosslinking domains is a vital factor to create functional hydrogels with controlled physical,mechanical,and adhesive *** paper demonstrates versatile synthetic systems of micelle-crosslinked hydrogels with highly stretchable,self-healing,and selectively adhesive *** this,methacrylate-bearing random copolymer micelles are designed as physical and covalent crosslink domains via the self-assembly of amphiphilic random copolymers carrying hydrophilic poly(ethylene glycol)(PEG),hydrophobic butyl or dodecyl groups,and methacrylate-terminal PEG in *** size,aggregation number,and pendant methacrylate number of the micelles are controlled by the composition and degree of *** are efficiently obtained from the free radical polymerization of hydrophilic monomers such as PEG acrylate and acrylamide in the presence of the micelle crosslinkers in *** to the dynamic yet selective chain exchange properties of the micelle domains,the hydrogels are highly stretchable up to over 1000%and show self-healing and selectively adhesive *** self-healing of hydrogels is promoted upon heating due to the fast chain exchange of the micelle domains,whereas hydrogels consisting of micelles with different alkyl groups are never adhesive because of their self-sorting properties.

关键词： adhesion hydrogel random copolymer micelle self-assembly self-healing self-sorting

Interventional radiology for post-transplant anastomotic complications

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Hepatoma Research 2017年第10期3卷 221-227页

作者： Toshiya shibata Department of Radiological Technology Faculty of Medical ScienceKyoto College of Medical ScienceKyoto 622-0041Japan Department of Radiology Kyoto University Graduate School of MedicineKyoto 606-8507Japan

The effectiveness of percutaneous interventional radiology for anastomotic stricture in hepatic vein, portal vein, and biliary tract after living donor liver transplantation (LDLT) is described. As a number of patients with LDLT are infants < 10-year-old in the study, the first treatment option was balloon dilatation, not primary stenting. However, stent placement was performed in patients with recurrent, repeated stenosis.

关键词： Interventional radiology living donor liver transplantation balloon dilatation stent placement

Effects of Pitavastatin on the Intima-Media Thickness of the Carotid Artery in Patients with Ischemic Stroke: The Pitavastatin Efficacy Study on Surrogate Markers and Imaging for Stroke (PESSMIST)

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World Journal of Neuroscience 2014年第4期4卷 306-312页

作者： Yasushi shibata Department of Neurosurgery University of Tsukuba Mito Medical Center Mito Kyodo General Hospital Mito Japan

Pitavastatin is a strong statin that was developed in Japan. The clinical impact of pitavastatin treatment in patients with ischemic stroke has not been reported. We conducted a prospective, open label, clinical case-control study to determine the secondary preventive effects of pitavastatin for patients with cerebral infarction and hyperlipidemia. The pitavastatin group included 20 Japanese patients diagnosed with cerebral infarction and hyperlipidemia without previous statin intake. The control group included 22 patients diagnosed with cerebral infarction without hyperlipidemia. The pitavastatin group of patients received 2 mg of pitavastatin once a day after dinner. The mean age of the patients was 69.3 and 75.5 years for the pitavastatin and control groups, respectively, and the age of the pitavastatin group was significantly younger than that of the control group (P < 0.05). The serum TCho and LDL-C levels significantly decreased two months after the initiation of pitavastatin treatment. The mean and maximum intima-media thickness (IMT) also decreased after the initiation of pitavastatin. The mean and maximum IMT did not show any significant changes in the control group. The change of IMT %/year was less than zero for the pitavastatin group, and was almost zero or higher for the control group. Pitavastatin showed beneficial effects by improving the surrogate makers of stroke. These surrogate makers were effective to evaluate the efficacy of pitavastatin to prevent secondary stroke. Although a prospective randomized study is required to elucidate the long-term effects of pitavastatin, the current study suggests that pitavastatin may be effective to prevent secondary stroke in patients with stroke and hyperlipidemia.

关键词： Pitavastatin Stroke ECHO IMT Hyperlipidemia

SOA Direct Modulation in Wavelength-Selectable Laser Array Light Sources

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光学学报 2003年第S1期23卷 431-432页

作者： Kazuo Kasaya Ken Tsuzuki Hiroaki Sanjoh Yasuo shibata Yuichi Tohmori NTT Photonics Laboratories NTT Corporation 3-1 Morinosato Wakamiya Atsugi-shi Kanagawa Pref 243-0198 Japan

We demonstrated, for the first time, 2.5-Gb/s SOA direct modulation in the wavelength-selectable DFB laser array. The SOA direct modulation was achieved in the wide tuning range of 22.7nm by selecting arrayed laser an... 详细信息

关键词： DFB laser range of