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Endoscopic features and prognoses of mantle cell lymphoma with gastrointestinal involvement

World Journal of Gastroenterology 2010年第37期16卷 4661-4669页

作者： Masaya Iwamuro Hiroyuki Okada Yoshiro Kawahara katsuji shinagawa Toshiaki Morito Tadashi Yoshino Kazuhide Yamamoto Department of Gastroenterology and Hepatology Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences Department of Hematology and Oncology Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences Department of Pathology Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences

AIM: To evaluate the endoscopic manifestations and prognoses of gastrointestinal (GI) mantle cell lymphoma (MCL). METHODS: A database search at the Department of Pathology of Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences revealed 57 MCL patients with GI involvement. Clinical records were available for 35 of the 57 patients from 21 institutions, and those 35 patients were enrolled in this study. We summarized the gross types of endoscopic features, event-free survival (EFS), and overall survival (OS) of those ***: Of the 35 patients, GI involvement in the esophagus, stomach, and duodenum was found in 2 (5.7%), 26 (74.3%), and 12 (34.3%) patients, respectively. Twenty-one of the 35 patients underwent colonoscopy; among them, GI involvement in the ileum, cecum, colon, and rectum was found in 10 (47.6%), 3 (14.3%), 12 (57.1%), and 10 (47.6%), respectively. Various lesions, such as superficial, protruded, fold thickening, or ulcerative, were found in the stomach, whereas multiple lymphomatous polyposis (MLP) was dominant from the duodenum to the rectum. Twelve patients were treated with a hyper-CVAD/MA regimen, and they had better OS (3-year rate, 88.3% vs 46.4%, P < 0.01) and better EFS (3-year rate, 66.7% vs 33.8%, P < 0.05) than the remaining 23 patients who were not treated with this regimen. CONCLUSION: MLP was a representative form of intestinal involvement, whereas a variety of lesions were found in the stomach. The hyper-CVAD/MA regimen may improve survival in these patients.

关键词： Chemotherapy Gastrointestinal lymphoma Mantle cell lymphoma Multiple lymphomatous polyposis Non-Hodgkin’s lymphoma

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Diagnostic role of 18F-fluorodeoxyglucose positron emission tomography for follicular lymphoma with gastrointestinal involvement

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World Journal of Gastroenterology 2012年第44期18卷 6427-6436页

作者： Masaya Iwamuro Hiroyuki Okada Katsuyoshi Takata katsuji shinagawa Shigeatsu Fujiki Junji Shiode Atsushi Imagawa Masashi Araki Toshiaki Morito Mamoru Nishimura Motowo Mizuno Tomoki Inaba Seiyu Suzuki Yoshinari Kawai Tadashi Yoshino Yoshiro Kawahara Akinobu Takaki Kazuhide Yamamoto Department of Gastroenterology and Hepatology Okayama University Graduate School of MedicineDentistryand Pharmaceutical SciencesOkayama 700-8558Japan Department of Endoscopy Okayama University HospitalOkayama 700-8558Japan Department of Pathology Okayama University Graduate School of MedicineDentistryand Pharmaceutical SciencesOkayama 700-8558Japan Department of Hematology and Oncology Okayama University Graduate School of MedicineDentistryand Pharmaceutical SciencesOkayama 700-8558Japan Department of Internal Medicine Tsuyama Central HospitalTsuyama 708-0841Japan Department of Internal Medicine Okayama Saiseikai General HospitalOkayama 700-8511Japan Department of Gastroenterology Mitoyo General HospitalKanonji 769-1695Japan Department of Internal Medicine Kagawa Rosai HospitalMarugame 763-8502Japan Department of Anatomic Pathology Kagawa Rosai HospitalMarugame 763-8502Japan Department of Internal Medicine Okayama Citizens' HospitalOkayama 700-8557Japan Department of Internal Medicine Hiroshima City HospitalHiroshima 730-8518Japan Department of Gastroenterology Kagawa Prefectural Central HospitalTakamatsu 760-8557Japan Department of Internal Medicine Sumitomo Besshi HospitalNiihama 792-8543Japan Department of Gastroenterology Onomichi Municipal HospitalOnomichi 722-8503Japan

AIM:To investigate the capacity for 18F-fluorodeoxyglucose(18F-FDG) positron emission tomography(PET) to evaluate patients with gastrointestinal lesions of follicular ***:This retrospective case series consisted of 41 patients with follicular lymphoma and gastrointestinal involvement who underwent 18F-FDG-PET and endoscopic evaluations at ten different institutions between November 1996 and October *** for endoscopic,radiological,and biological examinations performed were retrospectively reviewed from clinical records.A semi-quantitative analysis of 18F-FDG uptake was performed for each involved area by calculating the maximum standardized uptake value(SUVmax).Based on the positivity of 18F-FDG uptake in the gastrointestinal lesions analyzed,patients were subdivided into two *** identify potential predictive factors for 18F-FDG positivity,these two groups were compared with respect to gender,age at diagnosis of lymphoma,histopathological grade,pattern of follicular dendritic cells,mitotic rate,clinical stage,soluble interleukin-2 receptor levels detected by 18F-FDG-PET,lactate dehydrogenase(LDH) levels,hemoglobin levels,bone marrow involvement,detectability of gastrointestinal lesions by computed tomography(CT) scanning,and follicular lymphoma international prognostic index(FLIPI) ***:Involvement of follicular lymphoma in the stomach,duodenum,jejunum,ileum,cecum,colon,and rectum was identified in 1,34,6,3,2,3,and 6 patients,*** patient had esophageal *** total,19/41(46.3%) patients exhibited true-positive 18F-FDG uptake in the lesions present in their gastrointestinal *** contrast,false-negative 18F-FDG uptake was detected in 24 patients(58.5%),while false-positive 18F-FDG uptake was detected in 5 patients(12.2%).In the former case,2/19 patients had both 18F-FDG-positive lesions and 18F-FDGnegative lesions in the gastrointestinal *** patients with 18F-FDG avidity,the SUVmax value of the involved gast

关键词： Follicular lymphoma Gastrointestinal endoscopy F-fluorodeoxyglucose positron emission tomography Gastrointestinal lymphoma Duodenal neoplasm

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Photophysics and electrochemistry relevant to photocatalytic water splitting involved at solid–electrolyte interfaces

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Journal of Energy Chemistry 2017年第2期26卷 259-269页

作者： Tatsuya shinagawa Zhen Cao Luigi Cavallo Kazuhiro Takanabe King Abdullah University of Science and Technology(KAUST) KAUST Catalysis Center and Physical Sciences and Engineering Division(PSE)4700 KAUSTThuwal 23955-6900Saudi Arabia

Direct photon to chemical energy conversion using semiconductor–electrocatalyst–electrolyte interfaces has been extensively investigated for more than a half century. Many studies have focused on screening materials for efficient photocatalysis. Photocatalytic efficiency has been improved during this period but is not sufficient for industrial commercialization. Detailed elucidation on the photocatalytic water splitting process leads to consecutive six reaction steps with the fundamental parameters involved: The photocatalysis is initiated involving photophysics derived from various semiconductor properties(1: photon absorption, 2: exciton separation). The generated charge carriers need to be transferred to surfaces effectively utilizing the interfaces(3: carrier diffusion, 4: carrier transport). Consequently, electrocatalysis finishes the process by producing products on the surface(5: catalytic efficiency, 6: mass transfer of reactants and products). Successful photocatalytic water splitting requires the enhancement of efficiency at each stage. Most critically, a fundamental understanding of the interfacial phenomena is highly desired for establishing 'photocatalysis by design' concepts, where the kinetic bottleneck within a process is identified by further improving the specific properties of photocatalytic materials as opposed to blind material screening. Theoretical modeling using the identified quantitative parameters can effectively predict the theoretically attainable photon-conversion yields. This article provides an overview of the state-of-the-art theoretical understanding of interfacial problems mainly developed in our *** water splitting(especially hydrogen evolution on metal surfaces) was selected as a topic,and the photophysical and electrochemical processes that occur at semiconductor–metal, semiconductor–electrolyte and metal–electrolyte interfaces are discussed.

关键词： Photocatalysis Interface Water splitting Modeling Electrocatalysis Hydrogen evolution

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Continual few-shot patch-based learning for anime-style colorization

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Computational Visual Media 2024年第4期10卷 705-723页

作者： Akinobu Maejima Seitaro shinagawa Hiroyuki Kubo Takuya Funatomi Tatsuo Yotsukura Satoshi Nakamura Yasuhiro Mukaigawa The Research and Development Division OLM DigitalInc.Advanced Research GroupIMAGICA GROUPTokyo 1540023Japan Division of Information Science Graduate School of Science and TechnologyNara Institute of Science and TechnologyNara 6300192Japan Graduate School of Informatics Chiba UniversityChiba 2638522Japan

The automatic colorization of anime line drawings is a challenging problem in production *** advances in deep neural networks have addressed this problem;however,collectingmany images of colorization targets in novel anime work before the colorization process starts leads to chicken-and-egg problems and has become an obstacle to using them in production *** overcome this obstacle,we propose a new patch-based learning method for few-shot anime-style *** learning method adopts an efficient patch sampling technique with position embedding according to the characteristics of anime line *** also present a continuous learning strategy that continuously updates our colorization model using new samples colorized by human *** advantage of our method is that it can learn our colorization model from scratch or pre-trained weights using only a few pre-and post-colorized line drawings that are created by artists in their usual colorization ***,our method can be easily incorporated within existing production *** quantitatively demonstrate that our colorizationmethod outperforms state-of-the-art methods.

关键词： anime colorization few-shot learning continuous learning strategy

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从梅兰芳至今:日本的京剧接受史研究

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黄钟（武汉音乐学院学报） 2013年第3期 32-38页

作者：品川爱子中央音乐学院音乐学系

梅兰芳赴日公演为日本带来京剧艺术,也极力保持了中日两国的友谊。梅兰芳之后,日本京剧爱好者日益增多。两国演员和文化交流中相关人员认真而持续的活动,使得访日京剧演出得以定期上演,成为一门扎根于日本的异国艺术。京剧也与日本歌舞... 详细信息

梅兰芳赴日公演为日本带来京剧艺术,也极力保持了中日两国的友谊。梅兰芳之后,日本京剧爱好者日益增多。两国演员和文化交流中相关人员认真而持续的活动,使得访日京剧演出得以定期上演,成为一门扎根于日本的异国艺术。京剧也与日本歌舞伎保持着一定的交流,这是京剧在日本的独特发展特征。然而,日本民众对京剧艺术的理解仍存在片面的倾向。日本的京剧接受史引发了我们多方面的思考,如中日两国文化交流的长期友好关系,音乐作为连接两国文化桥梁的特殊力量,京剧独一无二的艺术特性等等具有启发性的话题。

关键词：京剧梅兰芳文化传播中日文化交流观众歌舞伎

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Granulation Technology of Raw Material for Sinter Ore in Tobata No.3 Sinter Plant

Granulation Technology of Raw Material for Sinter Ore in Tob...

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第八届（2011）中国钢铁年会

作者： Osamu Ishiyama Kenichi Higuchi Kazuyuki shinagawa Kohichi Ooyama Environmental and Process Technology Center Nippon Steel Corporation Yawata Works Nippon Steel Corporation

One of our key tasks in Tobata No. 3 Sinter Plant in Yawata Works, Nippon Steel Corp., is to reduce the consumption of expensive burnt lime, which is abundantly used to ensure the permeability of sinter beds. Conversely, as shown by many previous studies concerning the binder of raw material for sinter ore, no alternative to burnt lime has yet been developed and implemented. In this report, the development of a new binder that allows us to realize the intensified granulation of a raw material, its performance under lab-examination and the test operation of an actual plant are presented. Lab-examination results showed that the granular index can be improved when dispersant is added compounded together with micro-particles, and the highest effect on productivity improvement was identified in the pot test. An actual plant test was also implemented, targeting a reduction in burnt lime, through the improved permeability of sinter beds and with the intensified granulation of raw materials employing this new binder（micro-particles addition plus dispersant）. It was confirmed that a reduction of approximate 10 kg/t-sinter in burnt lime consumption unit could be achieved as productivity and sinter ore strength were maintained at an approximately constant level and operation stably secured. Meanwhile, the granulation index of the compounding raw materials and the permeability before ignition were retained at levels equivalent to those in the case of the base. Furthermore, synthetic binder consumption unit, including burnt lime and micro-particles additives, was reduced approximately 6 kg/t-sinter despite of adding micro-particle additives amounting to 4.3 kg/t-sinter.

关键词： granulation binder micro-particles

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向槽中投加盐的时候饮用水贮存槽的腐蚀防止方法

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水处理信息报导 2008年第6期 40-41页

作者： shinagawa, Akihiro

由不锈钢制成的用于贮存饮用水的贮存槽通过在槽内安装一种次氯酸盐发生电解设备并且向饮用水中投加产生的HCIO来防止设备腐蚀，在安装HCIO发生电解设备的同时，在槽内安装一种项部打开，且由底部和由一种绝缘材料制成的侧壁的容器，而... 详细信息

由不锈钢制成的用于贮存饮用水的贮存槽通过在槽内安装一种次氯酸盐发生电解设备并且向饮用水中投加产生的HCIO来防止设备腐蚀，在安装HCIO发生电解设备的同时，在槽内安装一种项部打开，且由底部和由一种绝缘材料制成的侧壁的容器，而后，该电解设备被安装在容器内。

关键词：设备腐蚀饮用水防止方法贮存加盐电解设备次氯酸盐安装

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游离氨基酸和甜菜碱类在海产海绵细胞内渗透压调节中的作用

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氨基酸杂志 1993年第4期15卷 43-46页

作者： Akira shinagawa 黄权吉林农业大学水产系长春市130118

本文分析了海绵纲中六种海产海绵体内所含的游离氨基酸和甜菜碱类,并研究了两种生活在潮间地带的海绵在低或高渗条件下所含成分浓度的变化。研究发现,在海绵体内富含游离氨基酸和甜菜碱类,其中以高含量的甘氨酸为特点。环甜菜碱的含量... 详细信息

本文分析了海绵纲中六种海产海绵体内所含的游离氨基酸和甜菜碱类,并研究了两种生活在潮间地带的海绵在低或高渗条件下所含成分浓度的变化。研究发现,在海绵体内富含游离氨基酸和甜菜碱类,其中以高含量的甘氨酸为特点。环甜菜碱的含量如龙虾肌碱和N-甲基烟酸内盐高于ω-甜菜碱如甜菜碱、β-丙氨酸甜菜碱和三甲铵丁内酯,其中N-甲基烟酸内盐在海绵Halichondria japonica中含量最高。虽然两种潮间地带海绵中游离氨基酸和甜菜碱类的浓度随盐度变化而波动,但这些成分总的变化是由于甘氨酸的作用。

关键词：海绵动物氨基酸甜菜碱渗透压

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Recovery of In Situ-generated Pd Nanoparticles with Linear Polystyrene

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Green and Sustainable Chemistry 2011年第2期1卷 19-25页

作者： Atsushi Ohtaka Ryozo Kuroki Takuto Teratani Tsutomu shinagawa Go Hamasaka Yasuhiro Uozumi Osamu Shimomura Ryoki Nomura Department of Applied Chemistry Faculty of EngineeringOsaka Institute of TechnologyOsakaJapan Electronic Materials Research Division Osaka Municipal Technical Research InstituteOsakaJapan Institute for Molecular Science(IMS) OkazakiJapan Nanomaterials and Microdevices Research Center Osaka Institute of TechnologyOsakaJapan

Palladium nanoparticles generated in situ for Suzuki coupling reactions and aerobic alcohol oxidation in water were recovered completely using linear polystyrene. The resultant polystyrene-stabilized palladium nanopar... 详细信息

关键词： Polystyrene Pd Nanoparticles Water Suzuki Coupling Alcohol Oxidation

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Syntheses of Soluble Biopolyimides Using 4-Aminophenylalanine

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Chinese Journal of Polymer Science 2020年第10期38卷 1117-1123,I0007页

作者： Kenji Takad Hiromasa Shinagaw Yuki Morita Manjit SGrewal Kazuya Taya Amit Kumar Tatsuo Kaneko Graduate Schoo/of Advanced Science and Technology Energy and Environment AreaJapan Advanced Institute of Science and Technology(AISTI1-1 AsahidaiNomiIshikawa923-1292Japan Marialnrganomeallics Laboratony Department ofChemisty Atma Ram Sanatan Dharma CllegeUniversity of DelhiNew Delhi-10021India

4-Aminophenylalanine(4APhe),an exotic amino acid which is obtained as a microorganism metabolite of glucose,is polycondensed with various tetracarboxylic dianhydrides as a diamine monomer to obtain poly(amic acid)*** thermal imidization of poly(amic acid)s is made at 220°C with stepwise heating from 100°*** of the obtained polyimides(PIs)exhibited good solubility in organic solvents such as N,N-dimethylformamide,N.N dimethylacetamide,and *** progress of imidization was observed by proton nuclear magnetic resonance and infrared spectroscopy to confrm that the imidization ratio was up to 98%.Carboxylate group of the side-chains of PIs affected their solubilities despite the high imidization ratio,and the solubility was lost for any organic solvents by decarboxylation at 280。C,confirmed from mass-loss of thermogravimetric ***,a new series of PIs were obtained with abilities of solvent-molding in PI state and thermal resistivityt enhancement by further heating after molding.

关键词： Bio-based polymers Polyimides Amino acids 4-Aminophenylalanine Soluble polyimides

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