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Postoperative mometasone irrigations improve quality of life in skull base tumor patients

World Journal of Otorhinolaryngology-Head and Neck Surgery 2023年第4期9卷 314-319页

作者： Mandy K.Salmon Rijul S.Kshirsagar Jacob G.Eide Auddie M.Sweis kathleen davin Aman Prasad Heather Ungerer Elizabeth Stevens Kevin Ig‐Izevbekhai Siddhant Tripathi Tran B.Locke Theodore Lin Brian M.Sweis Michael A.Kohanski Nithin D.Adappa James N.Palmer Department of Otorhinolaryngology—Headand Neck Surgery University of PennsylvaniaPhiladelphiaPennsylvaniaUSA Division of Otolaryngology—Head and Neck Surgery North Shore University Health SystemThe University of ChicagoEvanstonIllinoisUSA University of Cincinnati School of Medicine CincinnatiOhioUSA Department of Otolaryngology Baylor College of MedicineHoustonTexasUSA Lewis Katz School of Medicine Temple UniversityPhiladelphiaPennsylvaniaUSA Department of Neuroscience University ofMinnesotaMinneapolisMinnesotaUSA

Objectives:The use of topical corticosteroids to manage postoperative sinonasal symptoms after endoscopic skull base surgery (ESBS) has not been well *** quantified long‐term impact of postoperative steroid irrigations (SIs) on quality of life of patients after ***:Retrospective review of patients at the University of Pennsylvania undergoing ESBS from 2010 to *** on patient demographics and postoperative treatment with nasal saline irrigation twice daily with and without dissolved steroids (mometasone or budesonide) was ***,and 1‐,3‐,6‐,12‐,18‐,and 24‐month postoperative Sino‐Nasal Outcome Test (SNOT‐22) scores were ***:A total of 727 patients were assessed (53.4% males),with 479 patients in the no SI group and 248 patients in the SI *** SNOT‐22 scores did not differ significantly (P = 0.19).1‐,3‐,6‐,12‐,18‐,and 24‐month post‐op SNOT‐22 scores did not significantly differ between ***,mometasone irrigations resulted in significantly lower postoperative 2‐year SNOT‐22 scores compared to budesonide (P < 0.01) and saline (P = 0.03).Conclusions:Though corticosteroid irrigations are routine in managing inflammatory sinus disease,their role in postoperative management after ESBS for tumors is *** findings suggest that mometasone irrigation may be effective at improving postoperative quality of life in patients after ESBS.

关键词： postoperative steroid irrigations skull base tumors

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