检索结果-南通市图书馆

Maturation, proliferation and apoptosis of seminal tubule cells at puberty after administration of estradiol, follicle stimulating hormone or both

引用

Asian Journal of Andrology 2008年第4期10卷 585-592页

作者： Renata Walczak-Jedrzejowska Jolanta Slowikowska-Hilczer katarzyna marchlewska Krzysztof Kula Department of Andrology and Reproductive Endocrinology Medical University of Lodz Lodz 91-425 Poland

Aim： To assess proliferative and apoptotic potential of the seminiferous epithelium cells in relation to Sertoli cell maturation in newborn rats under the influence of estradiol, follicle stimulating hormone （FSH） or both agents given together. Methods： From postnatal day （PND） 5 to 15 male rats were daily injected with 12.5 μg of 1713-estradiol benzoate （EB） or 7.5 IU of human purified FSH （hFSH） or EB ＋ hFSH or solvents （control）. On postnatal day 16, autopsy was performed. Sertoli cell maturation/function was assessed by morphometry. Proliferation of the seminiferous epithelium cells was quantitatively evaluated using immunohistochemical labeling against proliferating cell nuclear antigen and apoptosis using the TUN-EL method. Results： Although EB inhibited Sertoli cell maturation and hFSH was not effective, a pronounced acceleration of Sertoli cell maturation occurred after EB ＋ hFSH. Whereas hFSH stimulated Sertoli cell proliferation, EB or EB ＋ hFSH inhibited Sertoli cell proliferation. All treatments significantly stimulated germ cell proliferation. Apoptosis of Sertoli cells increased 9-fold and germ cells 2-fold after EB, and was not affected by hFSH but was inhibited after EB ＋ hFSH. Conclusion： At puberty, estradiol inhibits Sertoli cell maturation, increases Sertoli and germ cell apoptosis but stimulates germ cell proliferation. Estradiol in synergism with FSH, but neither of the hormones alone, accelerates Sertoli cell maturation associated with an increase in germ cell survival. Estradiol and FSH cooperate to induce seminal tubule maturation and trigger first spermatogenesis.

关键词： estradiol follicle stimulating hormone germ cells Sertoli cells proliferation apoptosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Blood lipids may have influence on the emotional well-being in young men

引用

Health 2010年第5期2卷 441-447页

作者： Edyta Kramek Sylwia Jastrzebska Renata Walczak-Jedrzejowska katarzyna marchlewska Elzbieta Oszukowska Anna Guminska Krzysztof Kula Jolanta Slowikowska-Hilczer 不详

Anamnestic data on general health and medical conditions were achieved from 136 men (20-49 yrs). Beck Depression Inventory II (BDI-II) questionnaire was used to assess depressive symptomatology. Body weight, height, waist and hip circumference, arterial blood pressure were mea- sured. Serum levels of total cholesterol (TC), LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), triglicerydes (TG), glucose, SHBG, total testosterone, DHEA-S and estradiol were determined. Calculated were body mass index (BMI), waist to hip ratio (WHR) and free testosterone index (FTI). In men aged 40-49 general health significantly got worse, BMI, WHR, blood pressure increased and mean serum levels of FTI, DHEA-S, estradiol decreased in comparison to younger men. Only in 40-49 age band BDI-II scoring was negatively related with FTI, however, in the whole group there were no significant correlations. Nevertheless, some symptoms of depression were negatively related with LDL-C or HDL-C and positively with TG. Similar relations were found among young men, but not in the middle-aged. Conclusions: Only blood lipids may have influence on emotional well-being in young healthy men. The decreased testosterone level becomes probably the main risk factor for the lower mood in middle-aged men. Atherosclerosis risk factors and general health worsen with the advancing age, but they have no significant effect on psychological situation.

关键词： Man Depression Sex Steroids Lipids General Health

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Financial and non-financial determinants of the indebtedness of hospitals:the case of Poland

引用

Journal of Management Analytics 2024年第1期11卷 26-44页

作者： katarzyna Miszczyńska Elżbieta Antczak Department of Banking Faculty of Economics and SociologyUniversity of LodzLodzPoland Department of Spatial Econometrics Faculty of Economics and SociologyUniversity of LodzLodzPoland

The performance of Polish healthcare is still far from satisfactory,which is connected with growing indebtedness that adversely affects not only the development of healthcare but also the quality of medical services *** turn,the financial situation of hospitals depends on various indicators and the relationship between *** paper investigates the determinants of healthcare sector functioning in the context of hospitals’financial situation(dependent variable measured by total debt ratio).321 individual public units were examined between years 2007–*** specifically,the fixed effects panel data model in question measures and evaluates the impact of economic,regional,institutional,and social factors in determining the dependent *** study confirmed dependencies between financial and non-financial ratios along with their impact on the financial condition of studied *** management implications of our study lay the groundwork for the improvement of efficient resource management for public hospitals.

关键词： polish healthcare system hospitals’financial situation debt ratio panel data analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Blood lipids may have influence on the emotional well-being in young men

引用

Health（健康） 2010年第5期

作者： Edyta Kramek Sylwia Jastrzebska Renata Walczak-Jedrzejowska katarzyna marchlewska Elzbieta Oszukowska Anna Guminska Krzysztof Kula Jolanta Slowikowska-Hilczer

来源：评论

学校读者我要写书评

暂无评论

晚白垩世真兽类Zalamdalestes揭示哺乳动物独特的枢椎及其复杂的进化过程

引用

Science Bulletin 2024年第11期69卷 1767-1775页

作者： Patrick Arnold katarzyna Janiszewska 李茜 Jingmai K.O'Connor Lucja Fostowicz-Frelik Institute of Biochemistry and Biology University of PotsdamPotsdam D-14476Germany Environmental Paleobiology Department Institute of PaleobiologyPolish Academy of SciencesWarsaw 00-818Poland Key Laboratory of Evolutionary Systematics of Vertebrates Institute of Vertebrate Paleontology and PaleoanthropologyChinese Academy of SciencesBeijing 100044China The Field Museum of Natural History Chicago IL 60605USA Department of Organismal Biology and Anatomy The University of ChicagoChicago IL 60637USA Evolutionary Paleobiology Department Institute of PaleobiologyPolish Academy of SciencesWarsaw 00-818Poland

The typical mammalian neck consisting of seven cervical vertebrae(C1–C7)was established by the Late Permian in the cynodont forerunners of modern *** structure is precisely adapted to facilitate movements of the head during feeding,locomotion,predator evasion,and social ***,the clade including crown placentals,has a fossil record extending back more than 125 million years revealing significant morphological diversification in the *** very little is known concerning the early evolution of eutherian cervical morphology and its functional adaptations.A specimen of Zalambdalestes lechei from the Late Cretaceous of Mongolia boasts exceptional preservation of an almost complete series of cervical vertebrae(C2–C7)revealing a highly modified axis(C2).The significance of this cervical morphology is explored utilizing an integrated approach combining comparative anatomical examination across mammals,muscle reconstruction,geometric morphometrics and virtual range of motion *** compared the shape of the axis in Zalambdalestes to a dataset of 88 mammalian species(monotremes,marsupials,and placentals)using three-dimensional landmark *** results indicate that the unique axis morphology of Zalambdalestes has no close analog among living *** range of motion analysis of the neck strongly implies Zalambdalestes was capable of exerting very forceful head movements and had a high degree of ventral flexion for an animal its *** findings reveal unexpected complexity in the early evolution of the eutherian cervical morphology and suggest a feeding behavior similar to insectivores specialized in vermivory and defensive behaviors in Zalambdalestes akin to modern spiniferous mammals.

关键词： Atlas Axis Vertebral column Stem placental Morphology paleoecology

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Acute coalescent mastoiditis in a 16-month-old child due to Streptococcus pneumoniae infection

引用

Journal of Acute Disease 2024年第1期13卷 36-39页

作者： Magdalena Pszczołowska Monika Morawska-Kochman katarzyna Resler katarzyna Pękalska Tomasz Zatoński Department and Clinic of Otolaryngology Head and Neck SurgeryWrocław Medical UniversityBorowska 213WrocławPoland Department of General Radiology Interventional Radiology and NeuroradiologyWrocław Medical UniversityBorowska 213WrocławPoland

Rationale:Acute otitis media is a common disease in early childhood,and is usually caused by Streptococcus pneumoniae(***).Acute mastoiditis is a complication of acute otitis media and can involve not only the mucoperiosteum of the middle ear but can also spread to the periosteum by destroying the mastoid bone(acute coalescent mastoiditis).In addition,the infection can extend through the surrounding bones or the emissary veins beyond the mastoid’s air cells,leading to subperiosteal ***’s Concern:A 16-month-old female patient was hospitalized due to the purulent discharge of the left ear and the symptoms of right mastoiditis(swelling and redness of the skin).Diagnosis:Bilateral acute coalescent mastoiditis caused by *** *** computer tomography revealed bilateral bone destruction of the mastoid and abscesses found behind the auricle on both ***:The patient underwent intravenous antibiotic therapy and surgical ***:The patient was discharged 14 days after hospitalization with an improved ***:Improperly treated acute coalescent mastoiditis can lead to extracranial and intracranial complications,sometimes serious and even *** are prevalent in children under 2 years,in whom the disease progresses more rapidly and *** vaccination with a 13-valent vaccine may not result in sufficient immunity against ***,a predominant pathogen in children affected by acute coalescent mastoiditis.

关键词： Acute otitis media Acute coalescent mastoiditis Streptococcus pneumoniae Children Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Use of endoscopic ultrasound-guided gallbladder drainage as a rescue approach in cases of unsuccessful biliary drainage

引用

World Journal of Gastroenterology 2024年第1期30卷 70-78页

作者： Alessandro Fugazza Kareem Khalaf katarzyna M Pawlak Marco Spadaccini Matteo Colombo Marta Andreozzi Marco Giacchetto Silvia Carrara Chiara Ferrari Cecilia Binda Benedetto Mangiavillano Andrea Anderloni Alessandro Repici Division of Gastroenterology and Digestive Endoscopy Humanitas Research Hospital-IRCCSRozzano 20089MilanoItaly Division of Gastroenterology St.Michael’s HospitalUniversity of TorontoToronto M5B 1W8ONCanada Department of Anesthesia Humanitas Research Hospital-IRCCSRozzano 20089MilanoItaly Gastroenterology and Digestive Endoscopy Unit Forlì-Cesena HospitalsRomagna 47121Italy Gastrointestinal Endoscopy Unit Humanitas Mater DominiCastellanza 21100Italy Gastroenterology and Digestive Endoscopy Unit Fondazione IRCCS Policlinico San MatteoPavia 27100Italy

This narrative review provides an overview of the utilization of endoscopic ultrasound-guided gallbladder drainage(EUS-GBD)as a salvage approach in cases of unsuccessful conventional ***-GBD is a minimally invasive and effective technique for drainage in patients with acute cholecystitis with high risk of *** procedure has demonstrated impressive technical and clinical success rates with low rates of adverse events,making it a safe and effective option for appropriate ***,EUS-GBD can also serve as a rescue option for patients who have failed endoscopic retrograde cholangiopancreatography or EUS biliary drainage for relief of jaundice in malignant biliary ***,patient selection is critical for the success of EUS-GBD,and proper patient selection and risk assessment are important to ensure the safety and efficacy of the *** the field continues to evolve and mature,ongoing research will further refine our understanding of the benefits and limitations of EUS-GBD,ultimately leading to improved outcomes for patients.

关键词： Endoscopic ultrasound-guided gallbladder drainage Gallbladder drainage Acute cholecystitis Malignant obstruction Interventional endoscopic ultrasound Lumen-apposing metal stents

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Mechanistic insights into fasting-induced autophagy in the aging heart

引用

World Journal of Cardiology 2024年第3期16卷 109-117页

作者： Hannaneh Parvaresh katarzyna Paczek Md Abdul Alim Al-Bari Nabil Eid Department of Biology Faculty of ScienceFerdowsi University of MashhadMashhad ***Iran Department of Chiropractic International Medical UniversityKuala Lumpur 57000Malaysia Department of Pharmacy University of RajshahiRajshahi 6205Bangladesh Department of Anatomy Division of Human BiologySchool of MedicineInternational Medical UniversityKuala Lumpur 57000Malaysia

Autophagy is a prosurvival mechanism for the clearance of accumulated abnormal proteins,damaged organelles,and excessive lipids within mammalian cells.A growing body of data indicates that autophagy is reduced in aging *** reduction leads to various diseases,such as myocardial hypertrophy,infarction,and *** studies in animal models of an aging heart showed that fasting-induced autophagy improved cardiac function and *** improvement is related to autophagic clearance of damaged cellular components via either bulk or selective autophagy(such as mitophagy).In this editorial,we summarize the mechanisms of autophagy in normal and aging *** addition,the protective effect of fasting-induced autophagy in cardiac aging has been highlighted.

关键词： Aging Autophagy Heart Fasting Mitophagy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hypertrophic cardiomyopathy and left ventricular non-compaction:Distinct diseases or variant phenotypes of a single condition?

引用

World Journal of Cardiology 2024年第9期16卷 496-501页

作者： Natalia Przytuła Ewa Dziewięcka Mateusz Winiarczyk katarzyna Graczyk Agnieszka Stępień PawełRubiś Department of Cardiac and Vascular Diseases Saint John Paul II HospitalKrakow 31-202MAPoland Department of Cardiac and Vascular Diseases Institute of CardiologyJagiellonian University Collegium MedicumSaint John Paul II HospitalKrakow 31-202MAPoland

Hypertrophic cardiomyopathy(HCM)is a genetically determined myocardial disease characterized by an increased thickness of the left ventricle(LV)wall that cannot be solely attributed to abnormal loading *** may present with an intraventricular or LV outflow tract obstruction,diastolic dysfunction,myocardial fibrosis and/or ventricular *** HCM from other diseases associated with LV hypertrophy,such as hypertension,aortic stenosis,or LV non-compaction(LVNC),can at times be *** is defined by excessive LV trabeculation and deep recesses between trabeculae,often accompanied by increased LV myocardial *** studies indicate that the LVNC phenotype may be observed in up to 5%of the general population;however,in most cases,it is a benign finding with no impact on clinical ***,LVNC can occasionally lead to LV systolic dysfunction,manifesting as a phenotype of dilated or non-dilated left ventricular cardiomyopathy,with an increased risk of thrombus formation and arterial *** extreme cases,where LVNC is associated with a very thickened LV wall,it can even mimic *** is growing evidence of an overlap between HCM and LVNC,including similar genetic mutations and clinical *** raises the question of whether HCM and LVNC represent different phenotypes of the same disease or are,in fact,two distinct entities.

关键词： Left ventricle hypertrabeculation Hypertrophic cardiomyopathy Left ventricle non-compaction Left ventricle hypertrophy Left ventricle obstruction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Equation of state for boron nitride along the principal Hugoniot to 16 Mbar

引用

Matter and Radiation at Extremes 2024年第5期9卷 77-86页

作者： Huan Zhang Yutong Yang Weimin Yang Zanyang Guan Xiaoxi Duan Mengsheng Yang Yonggang Liu Jingxiang Shen katarzyna Batani Diluka Singappuli Ke Lan Yongsheng Li Wenyi Huo Hao Liu Yulong Li Dong Yang Sanwei Li Zhebin Wang Jiamin Yang Zongqing Zhao Weiyan Zhang Liang Sun Wei Kang Dimitri Batani National Key Laboratory of Plasma Physics Laser Fusion Research CenterChina Academy of Engineering PhysicsMianyang 621900China HEDPS Center for Applied Physics and Technologyand College of PhysicsPeking UniversityBeijing 100871China HEDPS Center for Applied Physics and Technologyand School of EngineeringPeking UniversityBeijing 100871China Institute of Plasma Physics and Laser Microfusion Hery 2301-497 WarszawaPoland Universitéde Bordeaux CNRSCEACELIA(Centre Lasers Intenses et Applications)UMR 5107F-33405 TalenceFrance Institute of Applied Physics and Computational Mathematics Beijing 100094China

The thermodynamic properties of boron nitride under extreme pressures and temperatures are of great interest and importance for materials science and inertial confinement fusion physics,but they are poorly understood owing to the challenges of performing experiments and realizing ab initio ***,we report the first shock Hugoniot data on hexagonal boron nitride at pressures of 5–16 Mbar,using hohlraum-driven shock waves at the SGIII-p laser facility in *** density functional theory molecular dynamics calculations closely match experimental data,validating the equations of state for modeling the shock response of boron nitride and filling a crucial gap in the knowledge of boron nitride properties in the region of multi-Mbar pressures and eV *** results presented here provide fundamental insights into boron nitride under the extreme conditions relevant to inertial confinement fusion,hydrogen–boron fusion,and high-energy-density physics.

关键词： boron Hugoniot extreme

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：