检索结果-南通市图书馆

Predicting carbon nanotube forest attributes and mechanical properties using simulated images and deep learning

在线全文

学校读者我要写书评

暂无评论

npj Computational Materials 2021年第1期7卷 1214-1224页

作者： Taher Hajilounezhad rina Bao Kannappan Palaniappan Filiz Bunyak Prasad Calyam Matthew R.Maschmann Mechanical&Aerospace Engineering University of MissouriColumbiaMOUSA Electrical Engineering and Computer Science University of MissouriColumbiaMOUSA

understanding and controlling the self-assembly of vertically oriented carbon nanotube(CNT)forests is essential for realizing their potential in myriad *** governing process–structure–property mechanisms are poorly understood,and the processing parameter space is far too vast to exhaustively explore *** overcome these limitations by using a physics-based simulation as a high-throughput virtual laboratory and image-based machine learning to relate CNT forest synthesis attributes to their mechanical *** CNTNet,our image-based deep learning classifier module trained with synthetic imagery,combinations of CNT diameter,density,and population growth rate classes were labeled with an accuracy of>91%.The CNTNet regression module predicted CNT forest stiffness and buckling load properties with a lower root-mean-square error than that of a regression predictor based on CNT physical *** results demonstrate that image-based machine learning trained using only simulated imagery can distinguish subtle CNT forest morphological features to predict physical material properties with high *** paves the way to incorporate scanning electron microscope imagery for high-throughput material discovery.

关键词： carbon properties overcome

双歧杆菌对机体肠道菌群稳态健康调控机制研究进展

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国乳品工业 2024年第8期52卷 33-39页

作者：李璇武俊瑞张鹤男唐嘉忆程欣钰潘越乌日娜沈阳农业大学食品学院沈阳110866 辽宁省食品发酵技术工程研究中心沈阳110161 沈阳市微生物发酵技术创新重点实验室沈阳110866

肠道是人体内一个复杂的微生态系统,其中存在着大量的微生物。这些微生物与人体相互依存并对人体的代谢、营养、免疫系统有重要作用。肠道菌群稳态一旦遭到破坏,可引发肠道及代谢方面的健康问题。双歧杆菌(Bifidobacterium)作为肠道固... 详细信息

肠道是人体内一个复杂的微生态系统,其中存在着大量的微生物。这些微生物与人体相互依存并对人体的代谢、营养、免疫系统有重要作用。肠道菌群稳态一旦遭到破坏,可引发肠道及代谢方面的健康问题。双歧杆菌(Bifidobacterium)作为肠道固有菌群之一,能够通过调控肠道菌群稳态维持肠道正常功能,然而其调节肠道菌群稳态的作用机制缺乏系统的总结。文章总结近5年国内外有关肠道菌群稳态及其对人体健康疾病的影响,阐明双歧杆菌通过与病原菌竞争肠黏膜粘附点、代谢难消化的寡糖、与微生物群交叉喂养、刺激免疫系统4种方式调节肠道菌群稳态,为进一步研究双歧杆菌维持肠道菌群平衡机制、靶向筛选和研制双歧杆菌微生态制剂提供参考。

关键词：双歧杆菌肠道菌群代谢肠道菌群紊乱微生态

Preparation,structural characterization and bioactivities of polysaccharides from mulberry(Mori Fructus)

在线全文

学校读者我要写书评

暂无评论

Food Bioscience 2022年第2期46卷 865-874页

作者： Yumeng Liu Yiming Liu Delun Mu Hui Yang Ying Feng Ruiqin Ji rina Wu Junrui Wu College of Food Science Shenyang Agricultural UniversityLiaoning Engineering Research Center of Food Fermentation TechnologyShenyang Key Laboratory of Microbial Fermentation Technology InnovationShenyang110866PR China College of Foreign Language Teaching Shenyang Agricultural UniversityShenyang110866PR China College of Animal Husbandry and Veterinary Medicine Shenyang Agricultural UniversityShenyang110866PR China College of Horticulture Shenyang Agricultural UniversityShenyang110866PR China

Mulberry(Mori Fructus),a highly promising functional food,has long exhibited multiple therapeutic effects as a tonic in traditional Chinese food and *** have been regarded as the pivotal pharmacological ingredient in *** this study,structural characterization and bioactivities of polysaccharides from mulberry(PFM-3)were *** results showed that PFM-3 was a pyranose containing carboxyl group,which was mainly composed of glucose(Glc)and a small amount of mannose(Man)and fucose(Fuc).The molecular weight of PFM-3 was 96.17 kDa,and the surface of PFM-3 was compact and uniform ***-3 markedly decreased lipid accumulation,triglyceride(TG)and low density lipoprotein cholesterin(LDL-C)on hyperlipidemia human hepatocellular carcinoma(HepG2)***-3 recovered nuclear morphometry and mitochondrial membrane potential(MMP),enhanced the activity of glutathione peroxidase(GPx)and decreased cell arrest in G2 phase on oxidative stress HepG2 *** addition,PFM-3 promoted the decline of tumor necrosis factor-α(TNF-α)and the augment of interleukin-10(IL-10)secretion on inflammatory mouse leukemia cells of monocyte macrophage(RAW 264.7).This work provides a certificate that PFM-3 could markedly improve cellular lipid accumulation,endogenous antioxidant defense capacity and inflammation levels to further use for treatment and amelioration of related diseases.

关键词： Polysaccharides from mulberry Structure analysis Oxidative stress Hyperlipidemia Inflammation

Kidney Stones Are Prevalent in Individuals with Pseudoxanthoma Elasticum, a Genetic Ectopic Mineralization Disorder

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Dermatology and Venereology 2020年第4期3卷 198-204页

作者： Ralph Douglas Allawh rina Terry Ian F. Terry Sharon F. uitto Jouni Li Qiao-Li Department of Dermatology and Cutaneous Biology The Sidney Kimmel Medical Collegeand The PXE International Center of Excellence in Research and Clinical CareThomas Jefferson UniversityPhiladelphiaPA 19107USA PXE International Inc.WashingtonDC 20008USA Jefferson Institute of Molecular Medicine Thomas Jefferson UniversityPhiladelphiaPA 19107USA

Objective:Pseudoxanthoma elasticum(PXE)is a rare genetic disorder caused by loss-of-function mutations in the ABCC6 *** PXE is characterized by ectopic mineralization of connective tissues clinically affecting the skin,eyes,and cardiovascular system,kidney stones were reported in some individuals with *** aim of this study is to determine whether kidney stones are an incidental finding or a frequent manifestation of ***:We first investigated the genetic basis of two siblings diagnosed with *** younger patient presented with recurrent kidney stones since 8 years ***,to address whether kidney stones are associated with PXE,the prevalence of kidney stones in a survey cohort of 563 respondents with PXE was compared to that of a general *** survey,National Health and Nutrition Examination Survey,with 28,629 ***:Genetic analysis in both patients identified compound heterozygous mutations in ABCC6,c.2787+1G>T,and c.3774_*** analysis of participants 20 years old and older revealed that 23.4%of PXE patients had previously had a kidney stone,a significant increase compared to 9.2%in the general population(P<0.01).In addition,17.8%of PXE patients reported their first kidney stone episode before age of 18 years ***:PXE correlates with an increased risk of developing kidney stones with considerable morbidity and health-care cost.

关键词： ectopic mineralization kidney stones pseudoxanthoma elasticum

口服降糖药和胰岛素对眼表治疗的影响(英文)

在线全文

学校读者我要写书评

暂无评论

国际眼科杂志 2013年第9期13卷 1747-1750页

作者： Burin Kklü akιr Yasemin Aslan katιrcιoglu Nurten nlü Hüseyin stün Remzi Kasιm Sunay Duman Bahcelievler市Orkide大街39/5号土耳其巴勒克埃西尔10050 安卡拉培训和研究医院眼科土耳其安卡拉06600

目的:描述和对比口服降糖药(OAD)和胰岛素治疗2型糖尿病患者眼表的效果。方法:在安卡拉卫生部培训和研究医院就诊的20例40眼口服降糖药患者,20例40眼胰岛素治疗患者,对照组的10例非糖尿病人作为研究对象。对所有患者进行常规眼科检查,Sc... 详细信息

目的:描述和对比口服降糖药(OAD)和胰岛素治疗2型糖尿病患者眼表的效果。方法:在安卡拉卫生部培训和研究医院就诊的20例40眼口服降糖药患者,20例40眼胰岛素治疗患者,对照组的10例非糖尿病人作为研究对象。对所有患者进行常规眼科检查,Schirmer试验,泪膜破裂时间分析和结膜印迹细胞学分析.比较三组的泪液功能参数,杯状细胞密度和鳞状上皮化生等级。记录视网膜病变及眼表疾病之间的关系。结果:口服降糖药患者泪膜破裂时间值明显低于其他组(P<0.05)。三组的杯状细胞密度和鳞状上皮化生等级相近。上皮细胞稍大,呈现更多的多边形的眼的中位数级为1级,并且嗜酸性染色胞浆和杯状细胞数量减少。视网膜病变与眼表疾病不相关。结论:口服降糖药患者的角膜前泪膜稳定性比其他组差。各组的印迹细胞学分析结果相似。

关键词：眼表糖尿病印迹细胞学

Improvement of different source function expressions in SWAN model for the Bohai Sea

在线全文

学校读者我要写书评

暂无评论

Progress in Natural Science:Materials International 2005年第8期15卷 720-724页

作者： YIN Baoshu1*, YANG Dezhou1, SHA rina 1,2 and CHENG Minghua1(1. Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China 2. Graduate School of the Chinese Academy of Sciences, Beijing 100039, China) Institute of Oceanology Chinese Academy of Sciences Qingdao 266071 China Graduate School Chinese Academy of Sciences Beijing 100039 China

The simulating wave nearshore （SWAN） wave model has been widely used in coastal areas, lakes and estuaries. However, we found a poor agreement between modeling results and measurements in analyzing the chosen four typical cases when we used the default parameters of the source function formulas of the SWAN to make wave simulation for the Bohai Sea. Also, it was found that at the same wind process the simulated results of two wind generation expressions （Komen, Janssen） demonstrated a large difference. Further study showed that the proportionality coefficient α in linear growth term of wave growth source function plays an unperceived role in the process of wave development. Based on experiments and analysis, we thought that the coefficient α should change rather than be a constant. Therefore, the coefficient α changing with the variation of friction velocity u*was introduced into the linear growth term of wave growth source function. Four weather processes were adopted to validate the improvement in the linear growth term. The results from the improved coefficient α agree much better with the measurements than those from the default constant coefficient α. Furthermore, the large differences of results between Komen wind generation expression and Janssen wind generation expression were eliminated. We also experimented with the four weather processes to test the new white-capping mechanisms based on the cumulative steepness method. It was found that the parameters of the new white-capping mechanisms are not suitable for the Bohai Sea, but Alkyon's white-capping mechanisms can be applicable to the Bohai Sea after amendments, demonstrating that this improvement of parameter α can improve the simulated results of the Bohai Sea.

关键词： waves SWAN model wave growth source function new proportionality coefficient formula.

油莎豆(Cyperus esculentus)耕作区作物残茬对农田风蚀的影响

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

干旱区地理 2022年第2期45卷 546-556页

作者：谭锦吴秀芹阮永健张欢冯梦馨莎日娜北京林业大学水土保持学院北京100083 宁夏盐池毛乌素沙地生态系统国家定位观测研究站宁夏盐池751500

油莎豆(Cyperus esculentus)是一种油料作物,其对土壤养分要求低,因此适合在我国北方风沙区推广种植,以调整农业种植结构。然而在采收过程中对土地的扰动,会潜在增加农田风蚀的风险,因此需要对油莎豆残茬的生态效益进行探究与评估。基... 详细信息

油莎豆(Cyperus esculentus)是一种油料作物,其对土壤养分要求低,因此适合在我国北方风沙区推广种植,以调整农业种植结构。然而在采收过程中对土地的扰动,会潜在增加农田风蚀的风险,因此需要对油莎豆残茬的生态效益进行探究与评估。基于野外集沙实验和风速廓线测定实验,对油莎豆与梭梭间作未采收、油莎豆纯作留4垄采6垄和油莎豆纯作留6垄采6垄3种残茬类型的防风固沙能力进行了系统研究。结果表明:油莎豆与梭梭间作残茬类型中的输沙通量最低,总输沙通量显著小于其他2种模式(P<0.05),并且空气动力学粗糙度(0.553 cm和1.156 cm)和摩阻速度(0.304和0.332)也最高。留4垄采6垄模式输沙通量随时间增加,甚至超过全采收模式,空气动力学粗糙度接近于0,且摩阻速度最低。留6垄采6垄模式输沙通量则介于前两者之间,空气动力学粗糙度为0.100 cm和0.137 cm,摩阻速度为0.240和0.272。总体而言,单一的宽条带式油莎豆残茬削减风速的作用不如高低穿插搭配的作物残茬。油莎豆种植可以考虑选择合适的采收间距及搭配合适的直立植物进行间作,以在油莎豆采收后漫长的休耕期进行留茬以减轻风蚀保护农田。休耕期合理的作物留茬是减轻土壤风蚀的关键措施之一,这对于干旱区农田的可持续发展具有重要的生态价值。

关键词：油莎豆作物残茬输沙通量风沙流空气动力学粗糙度摩阻速度

巯基化党参多糖对鼠李糖乳杆菌肠道黏附定植作用的影响

在线全文

学校读者我要写书评

暂无评论

食品科学技术学报 2022年第4期40卷 45-54页

作者：曹恺欣武俊瑞李默韩琦于博祁姝旖王子健乌日娜沈阳农业大学食品学院辽宁沈阳110866 辽宁省食品发酵技术工程研究中心辽宁沈阳110866 沈阳市微生物发酵技术创新重点实验室辽宁沈阳110866

益生菌的肠道黏附是其实现长期肠道定植的关键因素。为增加外源性益生菌的肠道黏附性,对前期分离所得党参多糖(CPP-2)采用羧甲基化和巯基化两步化学修饰法,制备巯基化党参多糖(sC-CPP-2)。通过体外黏附实验和激光共聚焦显微镜法分析在添... 详细信息

益生菌的肠道黏附是其实现长期肠道定植的关键因素。为增加外源性益生菌的肠道黏附性,对前期分离所得党参多糖(CPP-2)采用羧甲基化和巯基化两步化学修饰法,制备巯基化党参多糖(sC-CPP-2)。通过体外黏附实验和激光共聚焦显微镜法分析在添加sC-CPP-2情况下肠黏液对鼠李糖乳杆菌(LGG)的黏附效果,利用党参多糖及其修饰组分与海藻酸钠形成的复合薄膜,间接验证sC-CPP-2对LGG的黏附性,并利用流变仪和经典拉伸实验检测sC-CPP-2与肠道黏液之间的相互作用关系。结果表明:羧甲基党参多糖(C-CPP-2)的取代度为0.588±0.026,sC-CPP-2中巯基含量为(279.50±5.97)μmol/g,C-CPP-2经巯基化修饰后处于巯基和羧基共存状态。sC-CPP-2表面巯基可与LGG表面蛋白质上的半胱氨酸残基形成二硫键,增加LGG的肠道黏附性。sC-CPP-2与肠黏液的最大分离力为(101.82±5.78)mN,黏附总功为(120.07±6.81)μJ,二者间相互作用力增强,表观黏度变大,黏合力显著增强。sC-CPP-2能够起到连接LGG与肠黏液的中介作用,增强LGG的肠道黏附性,研究结果旨在为改善益生菌在肠道中的黏附定植作用的进一步研究提供参考。

关键词：党参多糖巯基化鼠李糖乳杆菌黏附作用肠道定植

在线全文

学校读者我要写书评

暂无评论

孕晚期血红蛋白水平与妊娠结局的关系

中华围产医学杂志 2018年第4期21卷 260-265页

作者：林莉魏玉梅王晨苏日娜冯慧杨慧霞北京大学第一医院妇产科 100034

目的探讨孕晚期血红蛋白水平与妊娠结局的关系。方法选取2013年6月至2015年5月在我国3个城市的21家医疗机构分娩的单胎且有孕晚期（孕≥28周）血红蛋白指标的38 624例孕妇作为研究对象。收集孕妇的人口学资料及临床信息。根据孕晚期血... 详细信息

目的探讨孕晚期血红蛋白水平与妊娠结局的关系。方法选取2013年6月至2015年5月在我国3个城市的21家医疗机构分娩的单胎且有孕晚期（孕≥28周）血红蛋白指标的38 624例孕妇作为研究对象。收集孕妇的人口学资料及临床信息。根据孕晚期血红蛋白水平，将孕妇分为贫血组（血红蛋白浓度〈110 g/L）6 256例、正常组（血红蛋白浓度≥110-〈130 g/L）22 484例、高值组（血红蛋白浓度≥130-〈150 g/L）9 460例、超高值组（血红蛋白浓度≥150 g/L）424例。采用单因素方差分析、χ2检验进行统计学分析。结果（1）与正常组比较，贫血组的早产、低出生体重儿、新生儿转儿科、新生儿并发症的发生率较高[4.9%（1 095/22 484）与6.9%（431/6 256），3.1%（708/22 484）与4.3%（272/6 256），6.2%（1 392/22 484）与9.2%（577/9 460），7.7%（1 741/22 484）与10.2%（640/6 256），χ2值分别为930.905、21.360、70.506及39.837，P值均〈0.001]；高值组的妊娠期高血压疾病、子痫前期的发生率较高[2.3%（515/22 484）与3.2%（305/9 406），1.4%（313/22 484）与1.7%（161/9 460），χ2值分别为23.203和6.072，P值均〈0.017]，但早产、新生儿转儿科、新生儿并发症的发生率较低[4.9%（1 095/22 484）与3.7%（346/9 460），6.2%（1 392/22 484）与5.5%（517/9 460），7.7%（1 741/22 484）与6.7%（631/9 460），χ2值分别为331.947、6.245及11.154，P值均〈0.017]；超高值组的妊娠期高血压疾病、子痫前期、低出生体重儿的发生率较高[2.3%（515/22 484）与4.7%（20/424），1.4%（313/22 484）与3.5%（15/424），3.1%（708/22 484）与5.2%（22/424），χ2值分别为10.742、13.575及6.512，P值均〈0.017]。（2）进一步对孕晚期血红蛋白水平进行浓度梯度分析发现，随着血红蛋白浓度的升高，妊娠期高血压疾病、子痫前期和低出生体重儿的发生率呈现类＂u＂形曲线变化；早产、新生儿转儿科、新生儿并发症的发生率则呈下降趋势，差异均有统计学意义（χ2值分别为31.233、16.147、25.618、85.383、97.824及68.677，P值均〈0.05）。结论孕晚期异常的血红蛋白水平包括贫血和高浓度血红蛋白与不良妊娠结局具有相关性。

关键词：妊娠晚期血红蛋白贫血妊娠结局