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Antidiarrheal and antimicrobial profiles extracts of the leaves from Trichilia emetica Vahl.(Meliaceae)

Asian Pacific Journal of Tropical Biomedicine 2015年第3期5卷 242-248页

作者： Kiessoun Konaté kassi yomalan Oksana Sytar Marian Brestic Unit of Formation in Sciences Applied and Technological(UFR/SAT) and Institute of Sciences of the Environment and the Rural Development(ISEDR).Polytechnic University of Dedougou Laboratory of Biochemistry and Applied Chemistry University of Ouagadougou Laboratory of Animal Physiology UFR BioscienceUniversity of Felix Houphouet Boigny of Abidjan Department of Plant Physiolgy and Ecology Taras Shevchenko National University of Kyiv Department of Plant Physiology.Slovak University of Agriculture

Objective:To evaluate and-diarrhoeal and antimicrobial activities of the bioactive fraction of Trichilia emetica in order to provide a scientific basis for the management of gastroenteritis in Burkina ***:To do this,polyphenols content of extract and fractions were ***,AlCl_3 methods and tannic acid respectively were used for polyphenols *** in vivo antidiarrhocal activity was done using Swiss albino mice of both *** vitro antimicrobial activity(disc-diffusion assay,minimum inhibitory concentration and minimum microbicidal concentration or minimal bactericidal concentration) was assessed using seven bacteria strains(Gram-negative and Gram-positive).Results:About our study,it was found that ethyl acetate fraction effective attenuation factior(EAF) elicits the higher total phenolics and total flavonoids contents compared to the extracts of leaves of Trichilici *** of Trichilia emetica Vahl..has positive effects in a dose dependent manner against diarrhoea induced by castor oil in experimental *** bioactive fraction also showed good antimicrobial activity against all tested Gram-negative and Grampositive bacteria *** was shown that experimental bacteria strains were more sensitive to the EAF effect compared to the ***:The obtained results allow justifying the traditional uses of Trichilia emetica and possess good antidiarrhoeal and antimicrobial activities of EAF from Trichilia *** of the present study have clearly supported the utilization of Trichilia emetica in Burkina Faso traditional medicine.

关键词： Trichilia emetica Bioactive fraction Antidiarrhoeal and antimicrobial profiles

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