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城市环境设计 2019年第2期118卷 62-73页

作者： Snorre Nash Andreas Klok Pedersen Agne Tamasauskaite Annette Birthe Jensen Ariel Joy Norback Wallner Ask Hvas Birgitte Villadsen Chris Falla Christoffer Gotfredsen Daruisz Duong Vu Hong David Zahle Esben Christoffersen Franck Fdida Ioana Fartadi Scurtu Jakob Andreassen Jakob Ohm Laursen Jakob Sand Jakub Matheus Wlodarczyk Jesper Bo Jensen Jesper Boye Andersen Julia Boromissza kasper reimer hansen Katarzyna Krystyna Siedlecka Katarzyna Stachura Kekoa Charlot Leszek Czaja Lone Fenger Albrechtsen Louise B?geskov Hou Mads Enggaard Stidsen Magnus Algreen Suhr Manon Otto Marta Christensen Mathias Bank Stigsen Michael Kepke Ole Dau Mortensen Ryohei Koike Sergiu Calacean S?ren Askehave Stefan Plugaru Stefan Wolf Thomas Jakobsen Randb?ll Tobias Hjortdal Tommy Bj?rnstrup Iwan Baan Kim Christensen 陈思瑾

"乐高之屋展现了乐高积木的无限可能性。通过系统的创造力,让所有年龄段的孩子都能够使用这些工具来创造他们自己的世界,并通过游戏的方式生活其中。最棒的是,建筑和乐高游戏都是这样的:使人们能够想象比现状更令人兴奋和更具表现力的... 详细信息

"乐高之屋展现了乐高积木的无限可能性。通过系统的创造力,让所有年龄段的孩子都能够使用这些工具来创造他们自己的世界,并通过游戏的方式生活其中。最棒的是,建筑和乐高游戏都是这样的:使人们能够想象比现状更令人兴奋和更具表现力的新世界,并为他们提供使之成为现实的技能。这就是孩子们每天用乐高积木来做的事情,这也是我们今天用真实的砖石在乐高之屋里完成的事情,使比伦德向真

关键词：乐高积木展览空间

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Hyperbaric Oxygen Treatment for Diabetic Retinopathy and Neuropathy in a Streptozotocin Induced Diabetic Rat Model

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Journal of Biomedical Science and Engineering 2021年第12期14卷 391-401页

作者： Jesper G. Madsen Martin N. Skov kasper hansen Christoffer Laustsen Niels Ejskjær Henning Andersen Michael Pedersen Department of Clinical Medicine Comparative Medicine Lab Aarhus University Aarhus Denmark Zoophysiology Department of Biology Aarhus University Aarhus C Denmark Department of Forensic Medicine Aarhus University Aarhus N Denmark Department of Clinical Medicine The MR Research Centre Aarhus University Aarhus Denmark Department of Clinical Medicine Aalborg University Aalborg Denmark Steno Diabetes Center North Denmark Aalborg University Hospital Aalborg Denmark Department of Neurology Aarhus University Hospital Aarhus Denmark

Aim: Diabetes Mellitus is a global public health challenge with major and potentially devastating complications, and concomitant complications include retinopathy and neuropathy due to hypoxia and microvascular dysfunction. In this study, we investigated the effect of hyperbaric oxygen therapy as a method to transiently improve tissue oxygenation on diabetic retinopathy and neuropathy in a streptozotocin induced type-1 diabetic rat model (Wistar). Methods: Streptozotocin induced type-1 diabetic rats received 10 sessions of 2-h hyperbaric oxygen exposures (pO2 = 309 kPa) over 2 weeks. Animals were exposed to light stimuli to produce light evoked potentials to estimate the effect of oxygen treatment on diabetic retinopathy. Sciatic nerves were exposed and stimulated to produce muscle evoked potential, which were recorded in the muscles of the foot and subsequently used to evaluate the effect of oxygen treatment on diabetic neuropathy. Results: We found significantly shorter light evoked potential latency and increased amplitude in hyperbaric oxygen treated animals. No change was found in nerve conduction. Conclusions: This study showed that hyperbaric oxygen therapy is a potentially effective treatment for diabetic retinopathy, improving both latency and amplitude of light evoked potentials.

关键词： Diabetic Neuropathy Diabetic Retinopathy Hyperbaric Oxygen Therapy

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Validation of a surgical model for posthepatectomy liver failure in rats

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Animal Models and Experimental Medicine 2023年第3期6卷 266-273页

作者： Andrea Lund Michelle Meier kasper Jarlhelt Andersen Marie Ingemann Pedersen Anders Riegels Knudsen Jakob Kirkegård Frank Viborg Mortensen Aarhus University Hospital Department of Upper Gastrointestinal and Hepato-Pancreato-Biliary SurgeryAarhus NDenmark

Background:The upper limit for liver resections in rats is approximately 90%.In the early postoperative phase,mortality *** aim of the present study was to validate the rat model of 90%partial hepatectomy(PH)as a model of post-hepatectomy liver failure(PHLF).Further,we wanted to test a quantitative scoring system as a detector of lethal outcomes caused by PHLF in ***:Sixty-eight rats were randomized to 90%PH,sham operation,or no ***,block randomization was performed based on time of euthanization:12,24,or 48 h after surgery.A general distress score(GDS)≥10 during the day or≥6 at midnight prompted early euthanization and classification as *** euthanized as planned were classified as *** euthanization,blood and liver tissue were collected,and liver-specific biochemistry was ***:Based on the biochemical results,all animals subjected to 90%PH expe-rienced *** rats were euthanized due to irreversible *** GDS increased for nonsurvivors within 12–18 h after *** mean time for euthaniza-tion was 27 h after ***:Based on the GDS and liver-specific biochemistry,we concluded that the model of 90%PH seems to be a proper model for investigating PHLF in *** a high GDS is associated with increased mortality,the GDS appears to be valuable in detect-ing lethal outcomes caused by PHLF in rats.

关键词： 90%liver resection general distress score liver failure post-hepatectomy liver failure rats

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质朴北欧风

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现代装饰（家居） 2015年第8期 68-75页

作者： Alexa Lixfeld Broste Copenhagen Hallgeir Homstvedt kasper Rφnn&Jonas Bjerre-Poulsen Murken hansen Roger Arquer Tine K Home 伏平范嘉苑

北欧有着漫长的冬季，气温反差较大。但是这里森林茂密、水域辽阔，为设计师们提供了丰富的自然资源。他们不仅从美丽的大自然中汲取灵感，而且有效地利用这种天赋的资源，产品的设计基本上使用未经精细加工的原木，以最大限度地保留材... 详细信息

北欧有着漫长的冬季，气温反差较大。但是这里森林茂密、水域辽阔，为设计师们提供了丰富的自然资源。他们不仅从美丽的大自然中汲取灵感，而且有效地利用这种天赋的资源，产品的设计基本上使用未经精细加工的原木，以最大限度地保留材质原始的色彩和质感，彰显独特的风格与魅力。

关键词：欧风自然资源精细加工设计师大自然

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Hyperbaric Oxygen Treatment for Diabetic Retinopathy and Neuropathy in a Streptozotocin Induced Diabetic Rat Model

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Journal of Biomedical Science and Engineering（生物医学工程） 2021年第12期

作者： Jesper G. Madsen Martin N. Skov kasper hansen Christoffer Laustsen Niels Ejskjær Henning Andersen Michael Pedersen

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