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Experimental Study of Stable Surfaces for Anti-Slug Control in Multi-phase Flow

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International Journal of Automation and computing 2016年第1期13卷 81-88页

作者： Simon pedersen Petar Durdevic kasper Stampe Sandra Lindberg pedersen Zhenyu Yang Department of Energy Technology Aalborg University Esb jerg Campus

Severe slugging flow is always challenging in oil ＆ gas production, especially for the current offshore based production. The slugging flow can cause a lot of problems, such as those relevant to production safety~ fatigue as well as capability. As one typical phenomenon in multi-phase flow dynamics, the slug can be avoided or eliminated by proper facility d^sign or control of operational conditions. Based on a testing facility which can emulate a pipeline-riser or a gas-lifted production well in a scaled-down manner, this paper experimentally studies the correlations of key operational parameters with severe Slugging flows. These correlations are reflected through an obtained stable surface in the parameter space, which is a natural extension of the bifurcation plot. The maximal production opportunity without compromising the stability is also studied. Relevant studies have already showed that the capability, performance and efficiency of anti-slug control can be dramatically improved if these stable surfaces can be experimentally determined beforehand. The paper concludes that obtaining the stable surface on the new developed map can significantly improve the production rate in a control scheme. Even though the production rate can be further improved by moving the stable surface using advanced control strategies, the constant inputs can in some cases be preferable due to the easier implementation.

关键词： Offshore oil and gas anti-slug flow control production-rate optimization stabilization bifurcation.

Validation of a surgical model for posthepatectomy liver failure in rats

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Animal Models and Experimental Medicine 2023年第3期6卷 266-273页

作者： Andrea Lund Michelle Meier kasper Jarlhelt Andersen Marie Ingemann pedersen Anders Riegels Knudsen Jakob Kirkegård Frank Viborg Mortensen Aarhus University Hospital Department of Upper Gastrointestinal and Hepato-Pancreato-Biliary SurgeryAarhus NDenmark

Background:The upper limit for liver resections in rats is approximately 90%.In the early postoperative phase,mortality *** aim of the present study was to validate the rat model of 90%partial hepatectomy(PH)as a model of post-hepatectomy liver failure(PHLF).Further,we wanted to test a quantitative scoring system as a detector of lethal outcomes caused by PHLF in ***:Sixty-eight rats were randomized to 90%PH,sham operation,or no ***,block randomization was performed based on time of euthanization:12,24,or 48 h after surgery.A general distress score(GDS)≥10 during the day or≥6 at midnight prompted early euthanization and classification as *** euthanized as planned were classified as *** euthanization,blood and liver tissue were collected,and liver-specific biochemistry was ***:Based on the biochemical results,all animals subjected to 90%PH expe-rienced *** rats were euthanized due to irreversible *** GDS increased for nonsurvivors within 12–18 h after *** mean time for euthaniza-tion was 27 h after ***:Based on the GDS and liver-specific biochemistry,we concluded that the model of 90%PH seems to be a proper model for investigating PHLF in *** a high GDS is associated with increased mortality,the GDS appears to be valuable in detect-ing lethal outcomes caused by PHLF in rats.

关键词： 90%liver resection general distress score liver failure post-hepatectomy liver failure rats

Hyperbaric Oxygen Treatment for Diabetic Retinopathy and Neuropathy in a Streptozotocin Induced Diabetic Rat Model

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Journal of Biomedical Science and Engineering 2021年第12期14卷 391-401页

作者： Jesper G. Madsen Martin N. Skov kasper Hansen Christoffer Laustsen Niels Ejskjær Henning Andersen Michael pedersen Department of Clinical Medicine Comparative Medicine Lab Aarhus University Aarhus Denmark Zoophysiology Department of Biology Aarhus University Aarhus C Denmark Department of Forensic Medicine Aarhus University Aarhus N Denmark Department of Clinical Medicine The MR Research Centre Aarhus University Aarhus Denmark Department of Clinical Medicine Aalborg University Aalborg Denmark Steno Diabetes Center North Denmark Aalborg University Hospital Aalborg Denmark Department of Neurology Aarhus University Hospital Aarhus Denmark

Aim: Diabetes Mellitus is a global public health challenge with major and potentially devastating complications, and concomitant complications include retinopathy and neuropathy due to hypoxia and microvascular dysfunction. In this study, we investigated the effect of hyperbaric oxygen therapy as a method to transiently improve tissue oxygenation on diabetic retinopathy and neuropathy in a streptozotocin induced type-1 diabetic rat model (Wistar). Methods: Streptozotocin induced type-1 diabetic rats received 10 sessions of 2-h hyperbaric oxygen exposures (pO2 = 309 kPa) over 2 weeks. Animals were exposed to light stimuli to produce light evoked potentials to estimate the effect of oxygen treatment on diabetic retinopathy. Sciatic nerves were exposed and stimulated to produce muscle evoked potential, which were recorded in the muscles of the foot and subsequently used to evaluate the effect of oxygen treatment on diabetic neuropathy. Results: We found significantly shorter light evoked potential latency and increased amplitude in hyperbaric oxygen treated animals. No change was found in nerve conduction. Conclusions: This study showed that hyperbaric oxygen therapy is a potentially effective treatment for diabetic retinopathy, improving both latency and amplitude of light evoked potentials.

关键词： Diabetic Neuropathy Diabetic Retinopathy Hyperbaric Oxygen Therapy

心电图预激表现与心血管病和死亡风险的关系:哥本哈根心电图研究结果

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中华高血压杂志 2017年第10期25卷 989-989页

作者：刘莉叶鹏 Skov MW Rasmussen PV Ghouse J Hansen SM Graff C Olesen MS Pietersen A Torp-pedersen C HaunsS Kφber L Svendsen JH holst AG Nielsen JB

大部分心室预激患者临床发病过程中的心电图资料来源于三级医疗中心。为了调查患有心电图预激的初级保健人群的长期预后，来自丹麦哥本哈根Rigshospitalet心脏中心分子心脏病学实验室的研究人员在2001—2011年收集了328638例初级保健患... 详细信息

大部分心室预激患者临床发病过程中的心电图资料来源于三级医疗中心。为了调查患有心电图预激的初级保健人群的长期预后，来自丹麦哥本哈根Rigshospitalet心脏中心分子心脏病学实验室的研究人员在2001—2011年收集了328638例初级保健患者的电子心电图数据，确定了310例心电图显示预激（年龄8～85岁）的个体。并从丹麦全国注册管理机构获取关于患者药物、合并症和临床结局的资料。随访中位数为7．4（四分位间距4．6～10．3）年。

关键词：心电图数据心室预激哥本哈根死亡风险心血管病三级医疗中心临床发病过程初级保健

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城市环境设计 2019年第2期118卷 62-73页

作者： Snorre Nash Andreas Klok pedersen Agne Tamasauskaite Annette Birthe Jensen Ariel Joy Norback Wallner Ask Hvas Birgitte Villadsen Chris Falla Christoffer Gotfredsen Daruisz Duong Vu Hong David Zahle Esben Christoffersen Franck Fdida Ioana Fartadi Scurtu Jakob Andreassen Jakob Ohm Laursen Jakob Sand Jakub Matheus Wlodarczyk Jesper Bo Jensen Jesper Boye Andersen Julia Boromissza kasper Reimer Hansen Katarzyna Krystyna Siedlecka Katarzyna Stachura Kekoa Charlot Leszek Czaja Lone Fenger Albrechtsen Louise B?geskov Hou Mads Enggaard Stidsen Magnus Algreen Suhr Manon Otto Marta Christensen Mathias Bank Stigsen Michael Kepke Ole Dau Mortensen Ryohei Koike Sergiu Calacean S?ren Askehave Stefan Plugaru Stefan Wolf Thomas Jakobsen Randb?ll Tobias Hjortdal Tommy Bj?rnstrup Iwan Baan Kim Christensen 陈思瑾

"乐高之屋展现了乐高积木的无限可能性。通过系统的创造力,让所有年龄段的孩子都能够使用这些工具来创造他们自己的世界,并通过游戏的方式生活其中。最棒的是,建筑和乐高游戏都是这样的:使人们能够想象比现状更令人兴奋和更具表现力的... 详细信息

"乐高之屋展现了乐高积木的无限可能性。通过系统的创造力,让所有年龄段的孩子都能够使用这些工具来创造他们自己的世界,并通过游戏的方式生活其中。最棒的是,建筑和乐高游戏都是这样的:使人们能够想象比现状更令人兴奋和更具表现力的新世界,并为他们提供使之成为现实的技能。这就是孩子们每天用乐高积木来做的事情,这也是我们今天用真实的砖石在乐高之屋里完成的事情,使比伦德向真

关键词：乐高积木展览空间