检索结果-南通市图书馆

Benign course of residual inflammation at end of treatment of liver transplant recipients after sofosbuvir based therapy

引用

World Journal of Hepatology 2022年第3期14卷 602-611页

作者： Bahaaeldeen Ismail karim m benrajab Pablo Bejarano Phillip Ruiz Debbie Sears Andreas Tzakis Xaralambos Bobby Zervos Division of Digestive Diseases and Nutrition University of Kentucky College of MedicineLexingtonKY 40536United States Department of Pathology Cleveland Clinic FloridaWestonFL 33331United States Department of Pathology University of Miami Miller School of MedicineMiamiFL 33136United States Department of Liver Transplant Cleveland Clinic FloridaWestonFL 33331United States

BACKGROUND Persistent inflammation on histology after successful hepatitis C(HCV)treatment has been ***,data regarding the long-term impact in liver transplant recipients is limited,particularly after using direct-acting antiviral(DAA)*** To evaluate the impact of successful treatment with DAAs on histological changes and occult HCV and to describe the clinical course of residual inflammation in liver transplant *** We conducted a case series of 13 chronic HCV infected liver transplant recipients successfully treated with DAAs between December 2013 and may *** patients were treated for 24 wk and had non-detectable serum HCV RNA by the time of *** patients with at least one liver biopsy at or after treatment were *** examined liver biopsies for evidence of residual inflammation and the presence of intrahepatic HCV *** Persistent inflammation was seen in 12/13 patients on end of treatment *** was still seen in the available five follow-up biopsies(range 38-48 wk after the end of treatment).Intrahepatic HCV RNA was undetectable in all *** patients had preserved graft function for a mean follow-up of 2.5 years,except one that developed chronic *** After successful HCV treatment with DAAs,liver transplant recipients may have persistent inflammation on biopsy without evidence of intracellular *** clinical outcome remained favorable in most *** studies with a larger number and longer follow-up are needed to establish the implication of this finding on long-term graft function.

关键词： Immunosuppression Liver transplantation Recurrent hepatitis C Sustained virologic response Interferon

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Outcome of gastric antral vascular ectasia and related anemia after orthotopic liver transplantation

引用

World Journal of Hepatology 2020年第11期12卷 1067-1075页

作者： Saad Emhmed Ali karim m benrajab Anna Christina Dela Cruz Division of Hospital medicine Department of Internal MedicineUniversity of Kentucky College of MedicineLexingtonKY 40536United States Division of Digestive Diseases and Nutrition Department of Internal MedicineUniversity of Kentucky College of MedicineLexingtonKY 40536United States

BACKGROUND Gastric antral vascular ectasia(GAVE)is a significant complication of *** medical,surgical,and endoscopic treatment modalities have been proposed with varied satisfactory *** a few small studies,GAVE and associated anemia have resolved after orthotopic liver transplantation(OLT).AIm To assess the impact of OLT on the resolution of GAVE and related *** We retrospectively reviewed clinical records of adult patients with GAVE who underwent OLT between September 2012 and September *** and other relevant clinical findings were collected,including hemoglobin levels and upper endoscopy findings before and after *** primary outcome was the resolution of GAVE and its related anemia after *** Sixteen patients were *** pre-OLT Hgb was 7.7 g/dL and mean 12 mo post-OLT Hgb was 11.9 g/dL,(P=0.001).Anemia improved(defined as Hgb increased by 2g)in 87.5%of patients within 6 to 12 mo after OLT and resolved completely in half of the ***-OLT esophagogastroduodenoscopy was performed in 10 patients,and GAVE was found to have resolved entirely in 6 of those patients(60%).Although GAVE and associated anemia completely resolved in the majority of our patients after OLT,GAVE persisted in a few patients after *** studies in a large group of patients are necessary to understand the causality of disease and to better understand the factors associated with the persistence of GAVE post-transplant.

关键词： Liver cirrhosis Iron deficiency anemia End-stage liver disease Gastroscopy Gastrointestinal hemorrhage Liver transplantation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Preparation and Properties of PBXs Based on FOX-7 in Controlled Fragmentation Warhead Application

引用

含能材料 2018年第10期26卷 843-849页

作者： karim K Elsharkawy Lin Guo Ahmed m Enew School of Chemistry and Environment Beijing University of Aeronautics and Astronautics Chemical Department Faculty of EngineeringCairo University

Polymer bonded explosive(PBX)formulations were successfully prepared in the laboratory scale containing 1,1-diamino-2,2-dinitroethene(FOX-7)and hexogen(RDX)as brisant high explosives and different binder types of polyurethane(PU)based on glycidyl azide polymer(GAP) and hydroxyl-terminated polybutadiene(HTPB) as an energetic and inert polymeric binder *** technique was used for the preparation of different PBX formulations based on FOX-7/RDX and PU(GAP/HTPB)with 14% *** sensitivity to different initial impulses and performance characteristics of the explosive and lethal zone of the tested controlled fragmentation warhead by the fragmentation warhead assessment test(arena test)were studied,in which the arena test was carried out with a controlled fragmentation warhead made from Ck45 steel,with dimensions(100 mm length,30 mm outer diameter and 3 mm thickness).Results show that PBXGF4 has lower sensitivity to impact and heat than those of PBXGR4 by 188.4% and 3.2% *** friction sensitivity is the same as that of *** has better performance,in which detonation velocity increases by 2.1% and brisance increases by 0.5% when compared with those of *** was concluded that PBXGF4 which based on FOX-7 bonded with PU/GAP matrix has good characteristics as PBX,specially in the sensitivity to impact and can be applied for replacing PBXs based on RDX in the advanced PBXs for low sensitive fragmentation warheads.

关键词： polymer bonded explosive(PBX) controlled fragmentation warhead 1,1-diamino-2,2-dinitroethene(FOX-7) hexo-gen(RDX) preparation sensitivity performance characterization arena test

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Evaluation of antitumour activity of Calotropis gigantea *** bark against Ehrlich ascites carcinoma in Swiss albino mice

引用

Asian Pacific Journal of Tropical medicine 2011年第10期4卷 786-790页

作者： m Rowshahul Habib m Rezaul karim Department of Biochemistry and molecular Biology Faculty of ScienceRajshahi UniversityRajshahi-6205Bangladesh

Objective:To investigate experimentally the possible antitumor effect of methanol extract(mE) of Calotropis gigantea L.(***) root bark and its petroleum ether(PEF) and chloroform(CF) soluble fractions against Ehrlich ascites carcinoma(EAC) in Swiss albino ***:The effects of mE(10 and 20 mg/kg),PEF(40 and 80 mg/kg) and CF(20 and 40 mg/kg) on the growth of EAC and life span of EAC bearing mice were *** profile and biochemical parameters(SAI.P,SGPT and SCOT) were also ***:Results of in vivo study showed a significant decrease in viable tumor cell count and a significant increase of life span in the mE and CF treated group compared to untreated *** life span of mE and CF treated animals was significandy(Pmg mE/kg) and 57.07%(40 mg CF/kg).mE and CF brought back the hematological parameter more or less normal *** and CF also restored the altered levels of serum alkaline phosphatase(SALP) and serum glutamate oxaloacetate transaminase(SGOT).Conclusions:methanol extract(mE) of *** root bark and its chloroform soluble fraction(CF) possesses significant antitumor activity.

关键词： Calotropis gigantea Antitumor Ehrlich ascites carcinoma Root bark

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of Plasticizers,Antioxidants and Burning Rate modifiers on Aging Performance of the HTPB/HmDI Composite Solid Propellant

引用

含能材料 2019年第1期27卷 21-27,90页

作者： Ahmed m Enew Ehab Abadir Sahar Elmarsafy karim K Elsharkawy Chemical Department Faculty of EngineeringCairo University School of Chemistry and Environment Beijing University of Aeronautics and Astronautics

The effects of plasticizers,antioxidants and burning rate modifiers on the aging performance of the composite solid propellant based on hydroxyl-terminated polybutadiene(HTPB)/hexamethylene diisocyanate(HmDI)were explored by apply-ing an accelerated aging program for 90 day at 70 ℃. The HTPB propellant matrix with the diisooctyl sebacate(DOS)as plasti-cizers and diisooctyl azelate(DOZ), antioxidants as N,N ′-Diphenyl-p-phenylenediamine(AO) and 2,2′-methylenebis(4-methyl-6-tert-butylphenol)(cyanox 2246)and burning rate modifiers as barium ferrite(BF),copper chromites(CC)and fer-ric oxide(FO)were varied. Results show that sample(S1)which based on DOS decreases the stress value and increases the strain value which considered to be an excellent start for aging program. Sample(S3)containing AO presents the higher resis-tance to oxidation showing the better performance that reflects on increasing the shelf life of the composite solid propellant mo-tor. Sample(S5)which based on BF enhances the ballistic performance among over the other tested two samples. The accelerat-ed aging program allowed us to estimate the motor in-service lifetime.

关键词： polybutadiene(HTPB)/hexamethylene diisocyanate(HmDI)composite solid propellant plasticizers antioxidants burning rate modifiers aging program

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Rifaximin vs conventional oral therapy for hepatic encephalopathy:A meta-analysis

引用

World Journal of Gastroenterology 2012年第8期18卷 767-777页

作者： karim m Eltawil marie Laryea Kevork Peltekian michele molinari Department of Surgery and Transplantation Queen Elizabeth Ⅱ Health Sciences Center Dalhousie University Department of medicine Hepatology and Transplantation Queen Elizabeth Ⅱ Health Sciences Center Dalhousie University

AIm: To characterize the efficacy of rifaximin in the management of hepatic encephalopathy (HE) as several randomized controlled studies have shown contradictory results on its effectiveness in comparison to other oral agents. mETHODS: We performed a systematic review and random effects meta-analysis of all eligible trials identifi ed through electronic and manual searches. Twelve randomized controlled trials met the inclusion criteria with a total of 565 patients. RESULTS: The clinical effectiveness of rifaximin was equivalent to disaccharides or other oral antibiotics[odds ratio (OR) 0.96; 95% CI: 0.94-4.08] but with a better safety profi le (OR 0.27; 95% CI: 0.12-0.59). At the completion of treatment protocols, patients receiving rifaximin showed lower serum ammonia levels [weighted mean difference (WmD) = -10.65; 95% CI: -23.4-2.1; P = 0.10], better mental status (WmD = -0.24; 95% CI: -0.57-0.08; P = 0.15) and less asterixis (WmD -0.1; 95% CI -0.26-0.07; P = 0.25) without reaching statistical signifi cance. On the other hand, other psychometric outcomes such as electroencephalographic response and grades of portosystemic encephalopathy were superior in patients treated with rifaximin in comparison to the control group (WmD = 0.21, 95% CI: -0.33-0.09, P = 0.0004; and WmD = -2.33, 95% CI: -2.68-1.98, P = 0.00001, respectively). Subgroup and sensitivity analysis did not show any signifi cant difference in the above fi ndings. CONCLUSION: Rifaximin appears to be at least as effective as other conventional oral agents for the treatment of HE with a better safety profi le.

关键词： Hepatic encephalopathy Lactulose Neo-mycin Non-absorbable disaccharides Rifaximin

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Structural and opto-electrical properties of pyrolized ZnO-CdO crystalline thin films

引用

Journal of Semiconductors 2015年第5期36卷 1-7页

作者： A.m.m.Tanveer karim m.K.R.Khan m.mozibur Rahman Department of Physics Rajshahi University of Engineering & Technology Department of Physics University of Rajshahi

A series of ZnO-CdO thin films of different molar ratios of Zn and Cd have been deposited on glass sub- strate at substrate temperature -360℃ by the spray pyrolysis technique at an ambient atmosphere. X-ray diffraction （XRD） studies confirmed the polycrystalline nature of the film and modulated crystal structures ofwurtzite （ZnO） and cubic （CdO） are formed. The evaluated lattice parameters, and crystallite size are consistent with literature. Dislocation density and strain increased in the film as the grain sizes of ZnO and CdO are decreased. The band gap energy varies from 3.20 to 2.21 eV depending on the Zn/Cd ratios in the film. An incident photon intensity dependent I-V study confirmed that the films are highly photosensitive. Current increased with the increase of the intensity of the light beam. The optical conductivity and the optical constants, such as extinction coefficient, refractive index and complex dielectric constants are evaluated from transmittance and reflectance spectra of the films and these parameters are found to be sensitive to photon energy and displayed intermediate optical properties between ZnO and CdO, making it preferable for applications as the buffer and window layers in solar cells.

关键词： ZnO-CdO buffer layers XRD spray pyrolysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

On Crossed Product Algebras over Henselian Valued Fields

引用

Algebra Colloquium 2020年第3期27卷 389-404页

作者： Driss Bennis karim mounirh Faculty of Sciences Research Center CeReMAR Mohammed V University in RabatRabatMorocco

Let D be a tame central division algebra over a Henselian valued field E,D be the residue division algebra of D,E be the residue field of E,and n be a positive *** prove that m_(n)(D)has a strictly maximal subfield which is Galois(resp.,abelian)over E if and only if m_(n)(D)has a strictly maximal subfield K which is Galois(resp.,abelian)and tame over E withГ_(K)■Г_(D),whereГ_(K)andГ_(D)are the value groups of K and D,*** partially generalizes the result proved by Hanke et *** 2016 for the case n=1.

关键词： (graded)Brauer group valued division algebras Henselization graded division algebras gauges

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Packet Synchronization Structure with Peak Detection Algorithm for mBOFDm UWB

Packet Synchronization Structure with Peak Detection Algorit...

引用

2006 8th International Conference on Signal Processing

作者： karim,A.m. Othman,m. Institute of microengineering and Nanoelectronics National University of Malaysia 43600 BANGISelangor Darul EhsanMalaysia

ISBN: (纸本)0780397371

＜正＞In multi-band Orthogonal Frequency Division multiplexing（mB-OFDm） wireless personal area networks（WPAN） system,a robust signal detection algorithm is required for practical hardware *** the literature,the signal detection algorithms for OFDm are based on correlating the received signal with a time delayed replica of itself The result of correlation is then compared with a threshold *** selection of the threshold value is very important for correct packet *** of the characteristics of the channel environment,the determination of a threshold value is not a trivial *** this paper,a structure for packet synchronization in mB-OFDm is designed which has a peak *** this case, the determination of the threshold value is eliminated by finding the peak values of the correlation value using our proposed algorithm.

关键词： Wireless local area networks (WLAN)

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Geochemistry of island arc assemblage in the Eastern Desert of Egypt and the role of Pan-African magmatism in crustal growth of the Arabian–Nubian Shield:A review

引用

Acta Geochimica 2024年第3期43卷 588-622页

作者： Abdel-Aal mAbdel-karim mohamed mHamdy Adel A.Surour Geology Department Faculty of ScienceZagazig UniversityZagazig 44519Egypt Geology Department Faculty of ScienceTanta UniversityTanta 31527Egypt Department of Geological Sciences Faculty of ScienceNew Galala City 43511Egypt Geology Department Faculty of ScienceCairo UniversityGiza 12613Egypt

Neoproterozoic island arc assemblage of the Arabian–Nubian Shield(ANS)in the Eastern Desert(ED)of Egypt comprises juvenile suites of metavolcanics(mV),large amounts of meta-sedimentary rocks(mS),and voluminous metagabbros-diorites(mGD)and syn-tectonic intrusions of older granitoids(OG).We report here the updates of these four rock units in terms of classification,distribution,chemical characteristics,geodynamic evolution,metamorphism,and *** addition,we discuss these integrated data to elucidate a reasonable and reliable model for crustal evolution in the *** main features of these rock units indicate their relation to each other and the geodynamic environment dominated by early immature oceanic island arcs to primitive continental *** information of the island arc metavolcanic and plutonic rocks(gabbros,diorites,tonalites,and granodiorites)furnish evidence of the genetic *** include proximity and a coeval nature in the field;all protolith magmas are subalkaline in nature following calc-alkaline series with minor tholeiitic affinities;common geochemical signature of the arc rocks and subduction-related magmatism;their similar enrichment in LREEs;and similar major element compositions with mafic melts derived from metasomatized mantle *** volcano-sedimentary and the OG rocks underwent multiphase deformation events whereas the mGD complexes deformed *** on the magmatic,sedimentological,and metamorphic evolutions constrained by geochronological data as well as the progressive evolutionary trend from extensional to compressional regimes,a possible gradual decrease in the subducted slab dip angle is the most infl uential in any geodynamic model for arc assemblage in the ED of Egypt.

关键词： Island arc assemblage magmatism Crustal growth Neoproterozoic Arabian–Nubian Shield Eastern Desert Egypt

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：