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NaCl胁迫对扁桃砧木可溶性蛋白质和脯氨酸含量的影响

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新疆农业大学学报 2005年第1期28卷 1-5页

作者：买合木提.卡热吾甫尔.巴拉提侯江涛克热木.伊力新疆农业大学园艺学院乌鲁木齐830052 新疆喀什地区农业广播学校喀什844000

利用3种扁桃砧木,进行不同浓度盐胁迫处理。结果表明:石头扁桃叶片可溶性蛋白质含量在NaCl胁迫下5,10,20d后随盐浓度的增大先升高后下降,但盐胁迫20d后比其他处理区下降幅度大。脯氨酸含量各处理区随盐浓度的增大而升高,盐胁迫5d和10d... 详细信息

利用3种扁桃砧木,进行不同浓度盐胁迫处理。结果表明:石头扁桃叶片可溶性蛋白质含量在NaCl胁迫下5,10,20d后随盐浓度的增大先升高后下降,但盐胁迫20d后比其他处理区下降幅度大。脯氨酸含量各处理区随盐浓度的增大而升高,盐胁迫5d和10d后浓度为350mmol/L时达到最大值,20d后各处理区出现大幅度下降趋势,而且盐浓度为350mmol/L处理区的植株因高盐浓度,处理时间长而死亡。桃扁桃叶片可溶性蛋白质含量在盐处理5d和10d后随盐浓度的增大先升高后下降,在300mmol/L时达到最大值,20d后随盐浓度的增加有明显下降。这说明桃扁桃受到一定的盐胁迫时间后才表现出反应。脯氨酸含量均随盐浓度的增大而迅速升高,在盐胁迫5,10,20d后均在浓度为350mmol/L时达到最大值。毛桃叶片可溶性蛋白质含量在10d和20d后各处理区都出现下降趋势。但20d后各处理区的变化趋势比较平缓,差异变化不太明显。脯氨酸含量均在浓度为350mmol/L时达到最大值,而且每个处理区积累的脯氨酸含量比其它两个砧木的pro含量高。5,10,20d的含量分别比对照提高了18.64倍、9.16倍和18.10倍。这就说明蛋白质达到平衡时,脯氨酸急剧上升。通过本研究初步判断毛桃具有较强的抗盐能力。

关键词： NaCl胁迫扁桃砧木可溶性蛋白质脯氨酸

库尔勒香梨历年冬季低温评价及严重冻害成因分析

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新疆农业大学学报 2008年第6期31卷 17-20页

作者：巴特尔.巴克克热木.伊力匡玉疆艾合买提.阿不都热依木新疆农业大学草业与环境科学学院乌鲁木齐830052 新疆农业大学林学与园艺学院乌鲁木齐830052 新疆巴音郭楞蒙古自治州农业技术推广中心库尔勒841000 新疆巴音郭楞蒙古自治州库尔勒市香梨研究中心库尔勒841000

通过评价1958-2008年库尔勒香梨越冬期间及早春低温资料,分析了历年冻害发生情况及冻害成因。结果表明:1958-2008年,气温异常偏低年份有9年,香梨发生了6次严重冻害,其中5次严重冻害发生在越冬期间,早春冻害1次(2005),剩余3年气温在临界... 详细信息

通过评价1958-2008年库尔勒香梨越冬期间及早春低温资料,分析了历年冻害发生情况及冻害成因。结果表明:1958-2008年,气温异常偏低年份有9年,香梨发生了6次严重冻害,其中5次严重冻害发生在越冬期间,早春冻害1次(2005),剩余3年气温在临界线附近,没有造成严重冻害;1958-1986年极端最低气温变化趋势基本正常,之后有升高趋势;2007-2008年冬季气温异常偏低,导致了大面积冻害;香梨冻害发生临界温度大致为-20℃;香梨冻害与极端低温、低温持续日数、降温幅度、降雪厚度及持续时间、立地条件及管理水平等因素有关。

关键词：库尔勒香梨低温评价冻害

Impact of previous cyst-enterostomy on patients' outcome following resection of bile duct cysts

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World Journal of Gastrointestinal Surgery 2016年第6期8卷 427-435页

作者： Mehdi Ouaissi Reza Kianmanesh Emilia Ragot Jacques Belghiti Pietro Majno Gennaro Nuzzo Remi Dubois Yann Revillon Daniel Cherqui Daniel Azoulay Christian Letoublon Frane is-Rene Pruvot Francois Paye Patrick Rat karim Boudjema Adeline Roux Jean-Yves Mabrut Jean-Francois Gigot Department of General and Digestive Surgery La Timone Hospital 13009 Marseille France Department of Digestive and Endocrine Surgery Robert Debré Hospital 51090 Reims France Department of HPB Surgery Beaujon Hospital 92110 Clichy France Department of Digestive Surgery Geneva University Hospital 1205 Geneva Switzerland Department of HPB Surgery Gemelli University Hospital 00168 Roma Italy Department of Pediatric Surgery Mother and Children Hospital 69677 Bron France Department of Pediatric Digestive Surgery Necker Hospital 75175 Paris France Department of Digestive and HPB Surgery Paul Brousse Hospital 94800 Villejuif France Department of Digestive and HPB Surgery Henri Mondor Hospital 94000 Creteil France Department of Digestive and HPB Surgery Henri Mondor Hospital 94000 Creteil France Department of Digestive surgery and Transplantation Claude Huriez Hospital 59037 Lille France Department of Digestive Surgery Saint Antoine Hospital 75012 Paris France Department of Digestive Surgery Dijon University Hospital 21000 Dijon France Department of HPB Surgery Pontchaillou Hospital 35033 Rennes France Pole Information Medicale Evaluation Recherche Unité de Recherche Clinique 69317 Lyon France Department of Digestive Surgery and Hepatic Transplantation La Croix-Rousse Hospital 69317 Lyon France Department of Abdominal Surgery and Transplantation Division of Hepato-Biliary and Pancreatic Surgery Cliniques Universitaires Saint-Luc 1200 Brussels Belgium

AIM:To analyze the impact of previous cyst-enterostomy of patients underwent congenital bile duct cysts(BDC) ***:A multicenter European retrospective study between 1974 and 2011 were conducted by the French Surgical *** Todani subtypes I and IVb were *** imaging studies and operative and pathology reports underwent central *** with and without a previous history of cystenterostomy(CE) were ***:Among 243 patients with Todani types I and IVb BDC,16 had undergone previous CE(6.5%).Patients with a prior history of CE experienced a greater incidence of preoperative cholangitis(75% vs 22.9%,P < 0.0001),had more complicated presentations(75% vs 40.5%,P = 0.007),and were more likely to have synchronous biliary cancer(31.3% vs 6.2%,P = 0.004) than patients without a prior *** morbidity(75% vs 33.5%;P < 0.0008),severe complications(43.8% vs 11.9%;P = 0.0026) and reoperation rates(37.5% vs 8.8%;P = 0.0032) were also significantly greater in patients with previous CE,and their Mayo Risk Score,during a median follow-up of 37.5 mo(range:4-372 mo) indicated significantly more patients with fair and poor results(46.1% vs 15.6%;P = 0.0136).CONCLUSION:This is the large series to show that previous CE is associated with poorer short-and longterm results after Todani types I and IVb BDC resection.

关键词： Bile duct cyst Congenital Biliary disease Cyst-enterostomy Long-term outcome

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卡塔尔Al Janoub体育场

当代建筑 2020年第6期 76-83页

作者： Annarita Papeschi Andreas Urff Antonio Monserrat Cynthia Du Edgar Payan Ermis Chavaltzi Fernando Poucell Ganesh Nimmala George King Ho-Ping Hsia Irene Guerra Jan Klaska Junyi Wang karim Muallem Karoly Markos Ming Cheong Moa Carlsson Mohamed Al-Jubori Nastassia Linau Paulo Flores Peter Irmscher Rafael Portillo Stephane Vallotton Thomas Soo Vincent Konate Yeena Yun Wen-Kai Li(Kevin) Luke Hayes(摄) 无不详扎哈·哈迪德建筑事务所 Hufton+Crow

随着卡塔尔之星国家足联阿米尔杯决赛的举办,Al Janoub体育场于2019年5月16日正式揭幕——这也是为2022年卡塔尔世界杯建造的第一个新体育场。Zaha Hadid建筑事务所和Aecom从2013年3月起便开始了体育场及周边新区的设计。作为2022年世... 详细信息

随着卡塔尔之星国家足联阿米尔杯决赛的举办,Al Janoub体育场于2019年5月16日正式揭幕——这也是为2022年卡塔尔世界杯建造的第一个新体育场。Zaha Hadid建筑事务所和Aecom从2013年3月起便开始了体育场及周边新区的设计。作为2022年世界杯的场地之一,Al Janoub体育场将举行联赛的小组赛和四分之一决赛。该体育场位于多哈以南23 km的Al Wakrah市,可直接从首都乘坐Red Line地铁线抵达。

关键词：建筑事务所体育场世界杯地铁线阿米尔卡塔尔

降低辐射剂量及迭代重建算法对检测模拟人体肝脏仿真模型中低对比度低密度的肝脏病变的影响——一项18名阅片者研究

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国际医学放射学杂志 2014年第5期 475-475页

作者： A.H.Goenka B.R.Herts N.A.Obuchowski A.N.Primak F.Dong W.karim 吴爽 Section of Abdominal Imaging Cleveland Clinic Foundation9500 Euclid AveMail Code L10ClevelandOH 44195

摘要目的评估低剂量扫描滤过反投影法(FBP)和基于原始数据域迭代重建算法(SAFIRE)在模拟人体腹部仿真模型中对低对比度低密度的肝脏病变检出的影响。材料与方

关键词：辐射剂量低密度 FBP 肝脏病变迭代重建算法低对比度仿真模型数学模型

辐射剂量、模体大小、集成电路探测器和迭代重建对模体影像噪声、对比噪声比、低对比分辨率以及肝脏低密度病变检出的影响

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国际医学放射学杂志 2016年第5期 573-573页

作者： A.H.Goenka B.R.Herts F.Dong N.A.Obuchowski A.N.Primak W.karim 张丹青 Department of Radiology Mayo Clinic

摘要目的在不同辐射剂量和模体大小条件下,采用分立电路探测器(DC)与滤过反投影技术(FBP)或集成电路探测器(IC)与迭代重建技术(IR)评估半拟人模体影像噪声、对比噪声比(CNR)对低对比度、低密度肝脏病变的检测能力。材料与方法在没有携... 详细信息

摘要目的在不同辐射剂量和模体大小条件下,采用分立电路探测器(DC)与滤过反投影技术(FBP)或集成电路探测器(IC)与迭代重建技术(IR)评估半拟人模体影像噪声、对比噪声比(CNR)对低对比度、低密度肝脏病变的检测能力。材料与方法在没有携带或携有5 cm厚脂肪模拟环(宽度,30 cm

关键词：对比噪声比低密度检出模体病变辐射剂量探测器肝脏噪声噪音

低剂量白细胞介素-2在11种自身免疫疾病中的免疫学和临床疗效:单中心开放临床试验

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英国医学杂志中文版 2019年第2期22卷 123-123页

作者： Michelle Rosenzwajg Roberta Lorenzon Patrice Cacoub Hang Phuong Pham Fabien Pitoiset karim El Soufi Claire RIbet Claude Bernard Selim Aractingi Beatrice Banneville Laurent Beaugerie Francis Berenbaum Julien Champey Olivier Chazouilleres Christophe Corpechot Bruno Fautrel Arsfene Mekinian Elodie Regnier David Saadoun Joe-Elie Salem Jeremie Sellam Philippe Seksik Anne Daguenel-Nguyen Valene Doppler Jeremie Mariau Eric Vicaut David Klatzmann 杨新蕾(译) 张卓莉(校) 不详北京大学第一医院

背景调节性T(Tregs)细胞可以预防自身免疫并控制炎症,在各种自身免疫性或自身炎症性疾病中的研究都表明Treg细胞不足。由于低剂量白细胞介素-2(low-dose interleukin-2,ld-IL2)能够扩增并激活Tregs细胞,因此ld-IL2具有广泛的治疗潜力。... 详细信息

背景调节性T(Tregs)细胞可以预防自身免疫并控制炎症,在各种自身免疫性或自身炎症性疾病中的研究都表明Treg细胞不足。由于低剂量白细胞介素-2(low-dose interleukin-2,ld-IL2)能够扩增并激活Tregs细胞,因此ld-IL2具有广泛的治疗潜力。目的我们通过一项临床试验观察ld-IL2治疗11种自身免疫性疾病中1种的效果,旨在评估ld-IL2的治疗潜力并选择疾病,以用于进一步的临床开发。方法本研究为前瞻开放性Ⅰ~Ⅱa期临床观察,入选了46例轻中度患者,诊断分别为类风湿关节炎、强直性脊柱炎、系统性红斑狼疮、牛皮癣、白塞病、肉芽肿性多血管炎、大动脉炎、克罗恩病、溃疡性结肠炎、自身免疫性肝炎或硬化性胆管炎。所有患者都接受了ld-IL2(100万IU/天)5天,然后每两周注射一次,维持6个月。所有患者均接受了深入的免疫监测和临床评估。结果在任何疾病类型以及任何合并药物治疗的患者中,ld-IL2都显示出了良好的耐受性。通过经典的免疫表型分析和广泛的免疫表型分析发现所有患者的Tregs细胞均被特异性地扩增激活,而效应T细胞没有被活化,提示ld-IL2具有临床疗效的前景。结论本研究中所采用的IL-2剂量和治疗方案可以选择性地激活和扩增Tregs细胞,并且对于不同的疾病种类以及不同的合并用药都是安全的。这一临床疗效以及初步结果可以为ld-IL2在各种自身免疫和自身炎症性疾病中开展Ⅱ期临床试验观察疗效提供了依据。试验注册号NCT01988506.

关键词：白细胞介素-2 自身免疫疾病临床疗效临床试验低剂量自身免疫性疾病免疫学免疫表型分析

多器官床旁即时超声在新型冠状病毒肺炎中的应用:国际专家共识

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中国呼吸与危重监护杂志 2021年第2期20卷 77-84页

作者：王臻(译) Arif Hussain Gabriele Via Lawrence Melniker Alberto Goffi Guido Tavazzi Luca Neri Tomas Villen Richard Hoppmann Francesco Mojoli Vicki Noble Laurent Zieleskiewicz Pablo Blanco Irene W.Y.Ma Mahathar Abd.Wahab Abdulmohsen Alsaawi Majid AI Salamah Martin Balik Diego Barca karim Bendjelid Belaid Bouhemad Pablo Bravo-Figueroa Raoul Breitkreutz Juan Calderon Jim Connolly Roberto Copetti Francesco Corradi Anthony J.Dean AndréDenault Deepak Govil Carmela Graci Young-Rock Ha Laura Hurtado Toru Kameda Michael Lanspa Christian B Laursen Francis Lee Rachel Liu Massimiliano Meineri Miguel Montorfano Peiman Nazerian Bret P.Nelson Aleksandar N.Neskovic Ramon Nogue Adi Osman JoséPazeli Elmo Pereira-Junior Tomislav Petrovic Emanuele Pivetta Jan Poelaert Susanna Price Gregor Prosen Shalim Rodriguez Philippe Rola Colin Royse Yale Tung Chen Mike Wells Adrian Wong Wang Xiaoting Wang Zhen Yaseen Arabi 中国人民解放军空军军医大学航空航天医学系陕西西安710032 Department of Cardiac Sciences King Abdulaziz Medical City and King Abdullah International Medical Research Center 不详

新型冠状病毒肺炎(简称新冠肺炎,COVID-19)自首次报道以来,已造成全球超一亿人感染,给各国的公共卫生体系造成了巨大威胁。新冠肺炎的临床表现以呼吸系统体征和症状为主,80%的患者症状轻微,约5%为危重症患者,常表现为急性呼吸窘迫综合征... 详细信息

新型冠状病毒肺炎(简称新冠肺炎,COVID-19)自首次报道以来,已造成全球超一亿人感染,给各国的公共卫生体系造成了巨大威胁。新冠肺炎的临床表现以呼吸系统体征和症状为主,80%的患者症状轻微,约5%为危重症患者,常表现为急性呼吸窘迫综合征(ARDS)。前期,由于缺乏相关研究,面对日益紧迫的临床困境,医务人员不得不借鉴采取一些经验性措施以应对疫情。

关键词：体征和症状肺炎公共卫生体系呼吸系统首次报道专家共识疫情

Ventilation practices in burn patients—an international prospective observational cohort study

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Burns & Trauma 2021年第1期9卷 47-57页

作者： Gerie J.Glas Janneke Horn Markus W.Hollmann Benedikt Preckel Kirsten Colpaert Manu Malbrain Ary Serpa Neto karim Asehnoune Marcello Gamma de Abreu Ignacio Martin-Loeches Paolo Pelosi Folke Sjoerg Jan M.Binnekade Berry Cleffken Nicole P.Juffermans Paul Knape Bert G.Loef David P.Mackie Perenlei Enkhbaatar Nadia Depetris Anders Perner Eva Herrero Lucia Cachafeiro Marc Jeschke Jeffrey Lipman Matthieu Legrand Johannes Horter Athina Lavrentieva Alex Kazemi Anne Berit Guttormsen Frederik Huss Mark Kol Helen Wong Therese Starr Luc De Crop Wilson de Oliveira Filho Joa Manoel Silva Junior Cintia M.C.Grion Marjorie Burnett Frederik Mondrup Francois Ravat Mathieu Fontaine Renan Le Floch Mathieu Jeanne Morgane Bacus Maite Chaussard Marcus Lehnhardt Bassem Daniel Mikhail Jochen Gille Aidan Sharkey Nicole Trommel Auke C.Reidinga Nadine Vieleers Anna Tilsley Henning Onarheim Maria Teresa Bouza Alexander Agrifoglio Filip Fredén Tina Palmieri Lynda E.Painting Marcus J.Schultz LAMiNAR investigators Academic Medical Center University of AmsterdamAmsterdamAZ 1105The Netherlands Department of Anaesthesia and Intensive Therapy Medical University of Lublin Aleje Racklawickie 1–20-059 Lublin–Poland AZ JAN PALFIJN GENT Watersportlaan 5–9000 Gent–Belgium ABC Medical School SaPauloBangúSP 5001Brazil Service d’Anesthésie Réanimation Chirurgicale Nantes 44093France University Hospital Carl Gustav Carus Dresden 01307Germany St James University Hospital Dublin D08 NHY1Ireland University of Genoa GenoaGE 16128Italy Linkoing University Hospital Linkoing 58185Sweden Maasstad Hospital RotterdamDZ 3079The Netherlands Red Cross Hospital BeverwijkLE 1942The Netherlands Martini Hospital GroningenNT 9728The Netherlands University of Texas Medical Branch GalvestonTX 77555USA Turin CTO Burn Center TurinTO 10126Italy Rigshospitalet Copenhagen 2100Denmark La Paz University Hospital Madrid 28046Spain Ross Tilley Burn Centre Sunnybrook Health Sciences CentreToronto M4N 3M5Canada Royal Brisbane and Women’s Hospital Queensland UniversityHerstonQLD 4029Australia Australian and New Zealand Intensive Care Research Centre.Monash University MelbourneVIC 3004Australia GH St-Louis-Lariboisière APHPParis 75010France BG Klinik Ludwigshafen Ludwigshafen 67071Germany Papanikoalou Hospital Thessaloniki 54621Greece Middlemore Hospital OtahuhuAuckland 2025New Zealand Haukeland University Hospital Bergen 5021Norway Uppsala University Hospital Uppsala 75185Sweden Concord Repatriation General Hospital NSW University of SydneyConcord 2139Australia Ziekenhuis Netwerk Antwerpen-Stuivenberg Antwerpen 2060Belgium Universidade de Sao Paulo Sao Paulo 01246-903Brazil Universidade Estadual de Londrina Londrina 86057-970Brazil Sunnybrook Health Sciences Centre Toronto M4N 3M5Canada CHU Lyon St Luc Lyon 69007France CHU Nantes Service dánesthesie reanimation chirugicale Nantes 44093France Hopital Roger Salengro CHRU LilleLille 59037France Saint-Louis Hospital Paris 75010France BG University Hospital Bergmannsheil Bo

Background:It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from *** study aimed to determine ventilation practices in burn intensive care units(ICUs)and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28(VFD-28).Methods:This is an international prospective observational cohort study including adult burn patients requiring mechanical *** tidal volume(V_(T))was defined as V_(T)≤8 mL/kg predicted body weight(PBW).Levels of positive end-expiratory pressure(PEEP)and maximum airway pressures were *** association between V_(T) and VFD-28 was analyzed using a competing risk *** settings were presented for all patients,focusing on the first day of *** also compared ventilation settings between patients with and without inhalation ***:A total of 160 patients from 28 ICUs in 16 countries were *** V_(T) was used in 74%of patients,median V_(T) size was 7.3[interquartile range(IQR)6.2–8.3]mL/kg PBW and did not differ between patients with and without inhalation trauma(p=0.58).Median VFD-28 was 17(IQR 0–26),without a difference between ventilation with low or high V_(T)(p=0.98).All patients were ventilated with PEEP levels≥5 cmH_(2)O;80%of patients had maximum airway pressures<30 cmH_(2)***:In this international cohort study we found that lung-protective ventilation is used in the majority of burn patients,irrespective of the presence of inhalation *** of low V_(T) was not associated with a reduction in *** registration:*** *** of registration:9 December 2014.

关键词： Mechanical ventilation Inhalation trauma Lung-protective Critical care