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Impact of cancer diagnosis on life expectancy by area-level socioeconomic groups in New South Wales, Australia: a population-based study

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Cancer Biology & Medicine 2024年第8期21卷 692-702页

作者： Md Mijanur Rahman Michael David David Goldsbury karen Canfell Kou Kou Paramita Dasgupta Peter Baade Xue Qin Yu The Daffodil Centre The University of SydneyA Joint Venture with Cancer Council NSWSydneyNSW 1340Australia School of Medicine and Dentistry Griffith UniversityGold CoastQLD 4222Australia Cancer Council Queensland BrisbaneQLD 4006Australia

Objective: Improvement in cancer survival over recent decades has not been accompanied by a narrowing of socioeconomic disparities. This study aimed to quantify the loss of life expectancy(LOLE) resulting from a cancer diagnosis and examine disparities in LOLE based on area-level socioeconomic status(SES).Methods: Data were collected for all people between 50 and 89 years of age who were diagnosed with cancer, registered in the NSW Cancer Registry between 2001 and 2019, and underwent mortality follow-up evaluations until December 2020. Flexible parametric survival models were fitted to estimate the LOLE by gender and area-level SES for 12 common ***: Of 422,680 people with cancer, 24% and 18% lived in the most and least disadvantaged areas, respectively. Patients from the most disadvantaged areas had a significantly greater average LOLE than patients from the least disadvantaged areas for cancers with high survival rates, including prostate [2.9 years(95% CI: 2.5±3.2 years) vs. 1.6 years(95% CI: 1.3±1.9 years)] and breast cancer [1.6 years(95% CI: 1.4±1.8 years) vs. 1.2 years(95% CI: 1.0±1.4 years)]. The highest average LOLE occurred in males residing in the most disadvantaged areas with pancreatic [16.5 years(95% CI: 16.1±16.8 years) vs. 16.2 years(95% CI: 15.7±16.7 years)] and liver cancer [15.5 years(95% CI: 15.0±16.0 years) vs. 14.7 years(95% CI: 14.0±15.5 years)]. Females residing in the least disadvantaged areas with thyroid cancer [0.9 years(95% CI: 0.4±1.4 years) vs. 0.6 years(95% CI: 0.2±1.0 years)] or melanoma [0.9 years(95% CI: 0.8±1.1 years) vs. 0.7 years(95% CI: 0.5±0.8 years)] had the lowest average ***: Patients from the most disadvantaged areas had the highest LOLE with SES-based differences greatest for patients diagnosed with cancer at an early stage or cancers with higher survival rates, suggesting the need to prioritise early detection and reduce treatment-related barriers and survivorship challenges to improve life expec

关键词： Cancer diagnosis life expectancy loss of life expectancy area-level socioeconomic status flexible parametric model

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Irrigation and nitrogen fertiliser optimisation in protected vegetable fields of northern China:Achieving environmental and agronomic sustainability

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Journal of Integrative Agriculture 2024年第3期23卷 1022-1033页

作者： Bingqian Fan Yitao Zhang Owen Fenton karen Daly Jungai Li Hongyuan Wang Limei Zhai Xiaosheng Luo Qiuliang Lei Shuxia Wu Hongbin Liu State Key Laboratory of Efficient Utilization of Arid and Semi-arid Arable Land in Northern China/Key Laboratory of Nonpoint Source Pollution Control Ministry of Agriculture and Rural Affairs/lnstitute of Agricultural Resources and Regional PlanningChinese Academy of Agricultural SciencesBeijing 100081China Institute of Geographic Sciences and Natural Resources Research Chinese Academy of SciencesBeijing 100101China Teagasc Environmental Research CentreWexford Y35Ireland Institute of Plant Nutrition Resources and Environmental SciencesHenan Academy of Agricultural SciencesZhengzhou 450002China

Globally,sub-optimal use of nitrogen (N) fertiliser and elevated N irrigation groundwater have led to high leached nitrate (NO_(3)^(–)) losses from protected vegetable field *** fertiliser and irrigation management in different soil types is crucial to reduce future N loads from such *** present 4-year study examined leached N loads from lysimeter monitoring arrays set up across 18 protected vegetable system sites encompassing the dominant soil types of northern *** treatments applied at each field site were:1) a high N and high irrigation input treatment (HNHI);2) a low N but high irrigation input treatment (LNHI) and 3) a low N with low irrigation input treatment (LNLI).Results showed that the mean annual leached total nitrogen loads from the HNHI,LNHI and LNLI treatments were 325,294 and 257 kg N ha^(–1) in the fluvo-aquic soil,114,100 and 78 kg N ha^(–1) in the cinnamon soil and 79,68 and 57 kg N ha^(–1) in the black soil,*** N dissolved in irrigation water in the fluvo-aquic soil areas was 8.26-fold higher than in the cinnamon areas.A structural equation model showed that N fertiliser inputs and leaching water amounts explained 14.7 and 81.8%of the variation of leached N loads,***,reducing irrigation water by 21.5%decreased leached N loads by 20.9%,while reducing manure N and chemical N inputs by 22 and 25%decreased leached N loads by only 9.5%. This study highlights that protected vegetable fields dominated by fluvo-aquic soil need management to curtail leached N losses in northern China.

关键词： agriculture water quality nitrate groundwater irrigation management

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Dispersion Relations in Diffraction in Time

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Applied Mathematics 2024年第7期15卷 464-468页

作者： Salvador Godoy karen Villa Departamento de Fsica Facultad de Ciencias Universidad Nacional Autnoma de Mxico Ciudad de Mxico Mxico

In agreement with Titchmarsh’s theorem, we prove that dispersion relations are just the Fourier-transform of the identity, g(x′)=±Sgn(x′)g(x′), which defines the property of being a truncated functions at the origin. On the other hand, we prove that the wave-function of a generalized diffraction in time problem is just the Fourier-transform of a truncated function. Consequently, the existence of dispersion relations for the diffraction in time wave-function follows. We derive these explicit dispersion relations.

关键词： Diffraction in Time Dispersion Relations Hilbert Transforms

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Depositional condition of Paleoproterozoic Francevillian carbonate rocks revisited from rare earth element contents

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Geoscience Frontiers 2024年第3期15卷 31-49页

作者： Satoshi Yoshida karen Bakakas Mayika Yuki Ishihara Mathieu Moussavou Hisashi Asanuma Tomohiko Sato Takafumi Hirata Cédric Ligna Yusuke Sawaki Amboise Edou-Minko Department of Earth Science and Astronomy The University of Tokyo3-8-1 Komaba Meguro-kuTokyo 153-8902Japan Center for Northeast Asian Studies Tohoku University41 KawauchiAoba-kuSendai 980-8576Japan Department of Geology Universitédes Sciences et Techniques de MasukuBP:90190025 FrancevilleGabon Department of Earth and Planetary Science The University of Tokyo7-3-1 HongoBunkyo-kuTokyo 113-0033Japan Geochemical Research Center The University of Tokyo7-3-1HongoBunkyo-kuTokyo 113-0033Japan Graduate School of Human and Environmental Studies Kyoto UniversityYoshida-nihonmatsuSakyo-kuKyoto 606-8501Japan Center for Fundamental Education Okayama University of Science1-1Ridai-choKita-kuOkayama CityOkayama 700-0005Japan

The Paleoproterozoic Francevillian Group in the eastern Gabonese Republic has been recently attracting increasing attention because it includes distinctive macroscopic structures interpreted as eukaryotic ***,its depositional setting and associated redox conditions need to be clearly *** clarify these,petrological studies and rare earth element(REE)abundances of carbonate rocks of the Francevillian Group in the Lastoursville basin were determined with ICP-MS coupled with a laser ablation sampling *** microscopic observations indicate that dolostones in this basin underwent the complicated diagenetic history,including sparitization,decomposition of organic matter,reduction of ferromanganese oxides,silicification,and later *** dolostones of lower Francevillian B(FB)Formation show heterogeneous textures formed by alterations during *** the alterations,changes of REE abundances and degrees of positive Y anomalies appear to have *** indicates that REE signatures in carbonate rocks can vary during *** high Mn contents in the dolostones of upper FB Formation were derived from the reduction of ferromanganese oxides in *** signatures of REE abundance in dolostones can be explained by the mixing of seawater and ferromanganese oxide *** that sense,the dolostones inherited the trace element characteristics of precursor ferromanganese oxides even after the diagenesis.Y/Ho values of the most primary parts of each sample exceed 33,the newly determined threshold value for marine carbonate rocks based on our *** magnitude of the La anomaly values also falls within the range of that of Holocene reefal *** indicate that a precursor of the dolostone of the Francevillian Group was deposited in a marine *** addition,presence of Ce anomalies in the upper FB Formation suggests that the Paleoproterozoic ocean was oxidized to such an ex

关键词： Carbonate diagenesis Francevillian Group LA-ICP-MS Seawater composition Y/Ho fractionation

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Ancient Hakka Walled Villages for Communities

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China Book International 2024年第1期 18-21页

作者： Gong Wenrui karen Cui Chinese Writers Association Society of Translators and Interpreters of British Columbia(STIBC)

This book reviews the history and process of the formation of Hakka and reveals the language characteristics,folk beliefs,and spiritual characteristics of the Hakka *** is an excellent book that systematically introdu... 详细信息

关键词： Ancient characteristics culture

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Optimal transcorneal electrical stimulation parameters for preserving photoreceptors in a mouse model of retinitis pigmentosa

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Neural Regeneration Research 2024年第11期19卷 2543-2552页

作者： Sam Enayati karen Chang Anton Lennikov Menglu Yang Cherin Lee Ajay Ashok Farris Elzaridi Christina Yen Kasim Gunes Jia Xie Kin-Sang Cho Tor Paaske Utheim Dong Feng Chen Schepens Eye Research Institute of Massachusetts Eye and Ear Department of OphthalmologyHarvard Medical SchoolBostonMAUSA Institute of clinical medicine Faculty of MedicineUniversity of OsloOsloNorway Department of Medical Biochemistry Oslo University HospitalUniversity of OsloOsloNorway Department of Ophthalmology Drammen HospitalVestre Viken Hospital TrustDrammenNorway Department of Histology and Embryology School of MedicineMarmara UniversityIstanbulTurkiye

Retinitis pigmentosa is a hereditary retinal disease that affects rod and cone photoreceptors,leading to progressive photoreceptor *** research supports the beneficial effect of electrical stimulation on photoreceptor *** study aims to identify the most effective electrical stimulation parameters and functional advantages of transcorneal electrical stimulation(tcES)in mice affected by inherited retinal ***,the study seeked to analyze the electric field that reaches the retina in both eyes in mice and post-mortem *** this study,we recorded waveforms and voltages directed to the retina during transcorneal electrical stimulation in C57BL/6J mice using an intraocular needle probe with rectangular,sine,and ramp *** investigate the functional effects of electrical stimulation on photoreceptors,we used human retinal explant cultures and rhodopsin knockout(Rho^(-/-))mice,demonstrating progressive photoreceptor degeneration with *** retinal explants isolated from the donors’eyes were then subjected to electrical stimulation and cultured for 48 hours to simulate the neurodegenerative environment in *** density was evaluated by rhodopsin *** vivo Rho^(-/-)mice were subjected to two 5-day series of daily transcorneal electrical stimulation using rectangular and ramp *** function and visual perception of mice were evaluated by electroretinography and optomotor response(OMR),*** was used to assess the morphological and biochemical changes of the photoreceptor and bipolar cells in mouse *** recordings indicated effective delivery of rectangular,sine,and ramp waveforms to the retina by transcorneal electrical stimulation,of which the ramp waveform required the lowest *** of the total conductive resistance of the post-mortem human compared to the mouse eyes indicated higher cornea-to-retina resistance in human *** tem

关键词： bipolar cells electrical stimulation neuroprotection photoreceptor degeneration retina retinal explants retinitis pigmentosa transcorneal electrical stimulation waveform

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The multistage genesis of the giant Dongshengmiao Zn-Pb-Cu deposit in western Inner Mongolia,China:Syngenetic stratabound mineralization and metamorphic remobilization

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Geoscience Frontiers 2016年第3期7卷 529-542页

作者： richen Zhong Wenbo Li Civil and Environmental Engineering School University of Science and Technology Beijing Key Laboratory of Orogenic Belts and Crustal Evolution School of Earth and Space SciencesPeking University

The genesis of the giant Dongshengmiao in the northern margin of the North China Block has been debated since its discovery in the 1950 s,because it shows geological and geochemical characteristics with both syngenetic and epigenetic *** has geological settings and sulfur and lead isotopic compositions that are similar with typical SEDEX（sedimentary exhalative） deposit,while the Zn-Pb-Cu mineralization was controlled by shear deformation and metamorphism,showing similarities with orogenic-type *** this contribution,both the syngenetic and epigenetic features of the Dongshengmiao are envisaged,and accounted for in the context of a genetic model with two metallogenic *** pyrite at the Dongshengmiao was mostly recrystallized during metamorphism,but finegrained texture was locally preserved,indicating its syngenetic *** the contrary,all the Zn-Pb-Cu ores observed in this study show characteristics of epigenetic hydrothermal mineralization that controlled by metamorphism and accompanying shear *** sulfur and lead isotopic compositions of sphalerite and galena indicate that they were in situ remobilized from a syngenetic stratabound source,and the oxygen and hydrogen isotopic ratios of ore-fluid indicate that the large-scale remobilization was assisted by metamorphic *** thermodynamic modeling indicates that the orefluid during remobilization has a great potential of transporting *** may account for the abnormally enriched Cu in the remobilized SEDEX *** metamorphic fluid might strip Cu from the fluid source during devolatilization,and overprint it on the Zn-Pb orebodies during remobilization.A secondary flowthrough modeling reveals that Zn- and Cu-sulfides would be preferentially redistributed in Fe-rich carbonates during remobilization,as a result of fluid-rock ***,a multistage genetic model is *** the development of the Proterozoic rift,stratabound Zn-Pb mineralization to

关键词： SEDEX Zn-Pb-Cu Metamorphism Remobilization Orogenic-type deposit

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Investigating the Influence of Glaucoma on the Quality of Life among Adult Patients

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International Journal of Clinical Medicine 2024年第2期15卷 88-100页

作者： Paul Mwale karen Tabalasa Abdishakur A. Muse Ke Min Department of Ophthalmology Zhongnan Hospital of Wuhan University Wuhan China

Background: Research exploring the influence of glaucoma on quality of life has gained momentum in recent years. Numerous studies have investigated the multifaceted aspects of quality of life in glaucoma patients, utilizing various assessment tools and methodologies. Objective: To determine the influence that glaucoma has on the quality of life among adult patients. Study site: kitwe teaching eye hospital, Zambia. Method: It was a cross-sectional study that was conducted from 30th June 2022 to 17th April 2023. The study included 106 diagnosed glaucoma patients who were above the age of 55 years. Data was collected using validated 25-item national eye institute visual function Questionnaire (NEI VFQ-25). The data was analyzed using SPSS version 26 and Microsoft excel to present frequencies and percentages that generated graphical presentation. Results: 62% of the participants worry about their eye sight most of the time, 26% sometimes and 12% a little time. 9% of the participants had little difficulty to read ordinary prints, 14% moderate difficulties and 58% extremely difficult. 40% of the participants could drive despite glaucoma damaging their eyes while 60% could not. Majority of the patients said it was difficult noticing things around them while walking or sitted in one place. There was a significant difference between effects of glaucoma on patients and the existing relationship between glaucoma and quality of life (ANOVA, p = 0.019 and ANOVA, p = 0.023). Conclusion: This study has demonstrated the magnitude of impact that glaucoma has on the Quality of Life (QoL) in diagnosed patients and the relationship between glaucoma and the Quality of Life. Due to the progressive visual loss, the amount of activities these patients would perform is negatively affected especially where social and economic activities are concerned which also affects their monthly earnings for those living in middle to low-income countries. Therefore, social welfare a

关键词： Glaucoma Quality of Life Glaucoma Patients

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淹水胁迫下6种北方花灌木光合特性及耐涝性评价

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植物生理学报 2024年第4期60卷 725-738页

作者：朱婧杨城刘思王茂良丛日晨孙宏彦北京市园林绿化科学研究院绿化植物育种北京市重点实验室城乡生态环境北京实验室北京100102 河北农业大学河北保定071001 涉县住房和城乡建设局城镇园林管理所河北邯郸056400 北京农学院北京102206

本研究以淹水胁迫0~15 d的重瓣榆叶梅、金钟花、水栒子、小花溲疏、圆锥绣球、欧洲荚蒾6种北方花灌木为试材,测定其根系生长、植株形态、光合气体交换和叶绿素荧光参数等变化。结果显示,重瓣榆叶梅、金钟花、水栒子、小花溲疏、圆锥绣球... 详细信息

本研究以淹水胁迫0~15 d的重瓣榆叶梅、金钟花、水栒子、小花溲疏、圆锥绣球、欧洲荚蒾6种北方花灌木为试材,测定其根系生长、植株形态、光合气体交换和叶绿素荧光参数等变化。结果显示,重瓣榆叶梅、金钟花、水栒子、小花溲疏、圆锥绣球5种花灌木根系干重、根总长、根表面积等根系指标随淹水时间的增加呈先增加后下降的趋势,欧洲荚蒾呈逐渐下降的趋势;6种花灌木的植物叶片的叶片含水率、比叶重、PSII最大光合效率(Fv/Fm)、单位反应中心吸收的光能(RC/ABS)以及潜在光合转化和利用能力(PI)等叶绿素荧光指标及净光合速率(Pn)、气孔导度(Gs)、胞间CO_(2)浓度(Ci)等光合指标较对照均减小。根据测定的指标通过主成分分析等对其耐涝性进行评价,结果表明,淹水胁迫导致植物根系发褐、腐烂;植株出现萎蔫、落叶甚至死亡;随着淹水时间的增加,6种花灌木出现不同程度的光合系统受损。主成分分析结果表明,淹水胁迫主要影响植物的根系,进一步影响植物光和系统,最终评价得出6种花灌木的耐涝性排序为欧洲荚蒾>金钟花>小花溲疏>水栒子>圆锥绣球>重瓣榆叶梅。

关键词：淹水胁迫根系变化形态特征光合特性叶绿素荧光特性花灌木

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LTSA-LE:A Local Tangent Space Alignment Label Enhancement Algorithm

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Tsinghua Science and Technology 2021年第2期26卷 135-145页

作者： Chao Tan Genlin Ji richen Liu Yanqiu Cao School of Computer Science and Engineering Southeast UniversityNanjing 210096 School of Computer Science and Technology Nanjing Normal UniversityNanjing 210023China

According to smoothness assumption,local topological structure can be shared between feature and label *** study proposes a new algorithm based on Local Tangent Space Alignment(LTSA)to implement the label enhancement *** general,we first establish a learning model for feature extraction in label space and use a feature extraction method of LTSA to guide the reconstruction of label ***,we establish an unconstrained optimization model based on the optimal theory presented in this *** model is suitable for solving problems with a large number of sample ***,the experiment results show that the algorithm can effectively improve the training speed and multilabel dataset prediction accuracy.

关键词： smoothness assumption feature manifold label manifold unconstrained optimization

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