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Epithelial-Myoepithelial Carcinoma of Parotid Gland—A Surprising Clinical Entity

Surgical Science 2012年第5期3卷 274-278页

作者： Jaimanti Bakshi Grace Budhiraja karan gupta Sourabha K. Patro Nalini gupta Department of Otolaryngology & Head-Neck Surgery & Department of Cytopathology PGIMER Chandigarh India

Objective: Objective of this study is to highlight the importance of considering clinical and radiological findings in parotid tumors before operating tumors with high suspicion of malignancy though reported as benign on histopathology. Material and Methods: 20 years old female patient underwent radical parotidectomy for epithelial-myoepithelial carcinoma of the left parotid gland which was diagnosed on FNAC. Contrast CT and contrast MRI also showed a tumor involving left parotid gland with destruction of ramus of mandible and loss of tissue planes medially & laterally. Facial nerve was infiltrated by tumor, thus sacrificed. Post operatively, patient had left facial palsy and was discharged after 7 days without any other sequelae. Postoperative histopathology showed pleomorphic adenoma with positive resection margins medially, superiorly & posteriorly. No further treatment was given in view of the benign nature of the tumor. Results: Patient was kept on monthly follow up and was disease free at one year follow up. Conclusion: Aggressive surgical treatment should be planned for malignant parotid tumors to give a better tumor free survival. Misdiagnosis can occur on FNAC as it can hit only one part of the tumor thus missing a malignant tumor or can interpret pleomorphic adenoma as epithelial-myoepithelial carcinoma.

关键词： Myoepithelial Parotid Carcinoma Pleomorphic Adenoma

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The evolution of sinus surgery in England in the last decade - An observational study

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2021年第3期7卷 240-246页

作者： Keshav Kumar gupta karan Jolly Navdeep Bhamra Max Sallis Osborne Shahzada Khuram Ahmed Department of Otolaryngology New Cross HospitalThe Royal Wolverhampton NHS TrustWolverhamptonWV100QPUnited Kingdom Department of Otolaryngology Queen Elizabeth HospitalUniversity Hospitals Birmingham NHS Foundation TrustBirminghamB152THUnited Kingdom

Background and objective::Sinus surgery has seen significant changes over the years with advancements in instruments,endoscopes and *** study aimed to use Hospital Episode Statistics(HES)data to review the total number of sinus related procedures performed in both adults and children across England and identify whether there were any trends across the study *** predicted an increase in endoscopic sinus procedures with a decline in open approaches to the paranasal ***::Data from HES was extracted for the years *** operative(OPCS-4)codes relevant to all sinus procedures between E12.1 and E17.9 were *** examination of overall sinus related procedures,further subgroup analysis was performed with regards to open or endoscopic ***::The total number of sinus procedures performed between 2010 and 2019 was 89,*** was an increase in endoscopic surgeries by 21.1%and a decrease of open surgeries 35.3%during this *** was an overall increase in maxillary,frontal and sphenoid sinus procedures,with a decrease in ethmoid sinus and lateral rhinotomy *** was an increase in the proportion of endoscopic cases overall by 5.7%and for all sinuses ***::Overall,we see an increase in sinus surgery over the last 9 years from 2010 to *** findings are in keeping with our initial *** our data set is limited by coding,and lack of patient factors,it represents most,if not all,of the data in England over a large study *** is therefore useful to add to previous studies when demonstrating the increasing popularity of endoscopic sinus surgery over open procedures.

关键词： Endoscopic sinus surgery Sphenoid Ethmoid Frontal Maxillary Sinus

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Nonselective beta‐blockers reduce mortality in patients with acute‐on‐chronic liver failure

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Portal Hypertension & Cirrhosis 2022年第1期1卷 15-22页

作者： Anand V.Kulkarni Madhumita Premkumar karan Kumar Juned A.Khan Baqar A.Gora Sowmya Tirumalle Sameer Shaik Mithun Sharma Rajesh gupta Nageshwar D.Reddy Padaki N.Rao Department of Hepatology AIG HospitalsHyderabadIndia Department of Hepatology PGIMERChandigarhIndia Department of Hepatology Mahatma Gandhi HospitalsJaipurIndia Department of Hepatology Hopewell HospitalLucknowIndia

Aim:Nonselective beta‐blockers(NSBBs)can reduce the incidence of complications in patients with cirrhosis and prolong *** safety and efficacy of NSBBs in real‐world settings in patients with acute‐on‐chronic liver failure(ACLF)identified by the Asian Pacific Association for the Study of Liver criteria are *** study aimed to assess the safety and efficacy of NSBBs in patients with Asian Pacific Association for the Study of Liver(APASL)‐defined ACLF Methods:In this retrospective,multicenter study,patients with ACLF with complete 30 days follow‐up from January 2019 to December 2021 were *** primary objective was to compare 30‐day mortality among standard of care(SOC)and NSBB(+SOC)*** secondary objectives were to compare the incidence of infection,variceal bleed,and recompensation among both the ***:A total of 346 patients were *** 26%(n=89)of them received NSBBs,while 74%(n=257)received only *** Kaplan-Meier analysis,the incidence of mortality was 21%(95%confidence interval[CI]:16.20-26.50)in SOC group compared to only 8%(95%CI:3.22-15.53)in NSBB group at Day 30(p=0.005).Similarly,mortality in SOC group was 63%(95%CI:56.81-69.00)compared to 46%(95%CI:35.44-57.00)in NSBB group at 1 year(p=0.001).NSBB therapy could not reduce the incidence of infections or variceal ***‐seven percent of patients in the SOC group and 73%of patients in the NSBB group(p<0.001)*** was prescribed in 77.5%and propranolol in 22.5%of ***:NSBBs reduce mortality without any effect on infection or variceal bleed in patients with ***,only one in four ACLF patients are suitable for NSBB therapy.

关键词： ACLF infection portal hypertension variceal bleed

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Preparation, Characterization, Dielectric, Piezoelectric and Ferroelectric Properties of Yttrium and Praseodymium Doped Lead Titanate Ceramics

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材料科学与工程（中英文B版） 2014年第10期4卷 293-301页

作者： karan Singh Vishal Singh Rashmi gupta Krishen Kumar Bamzai Crystal Growth & Materials Research Laboratory Department of Physics and Electronics University of Jammu Jammu India

Rare earth double doped lead titanate with general formula Pb1-x Prx Ti1-y YyO3 where x (praseodymium) = 0.02, 0.04, 0.06, 0.08 and y (yttrium) = 0.02 was synthesized by solid state reaction technique. X-ray diffraction analysis confirms single phase formation with perovskite structure having tetragonal phase. Micro-structural analysis shows formation of dense micro-structure with grain size calculated using average line intercepted method. Dielectric behavior as a function of temperature was found to decrease with Pr substitution. The diffusivity in the dielectric behavior was observed in all the compositions. Piezoelectric coefficient d33 and g33 was determined with increase in compositions of Pr substituent. The ferroelectric property was observed at room temperature and the value of remanent polarization (Pr), spontaneous polarization (Ps) and (EC) coercive field was calculated.

关键词：钛酸铅陶瓷介电行为压电系数镨掺杂铁电性能 X射线衍射分析制备表征

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