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Graphene： from synthesis to engineering to biosensor applications

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Frontiers of Materials Science 2018年第1期12卷 1-20页

作者： Jagpreet SINGH Aditi rathi Mohit RAWAT Manoj GUPTA Department of Nanotechnology Sri Guru Granth Sahib World University Fatehgarh Sahib-140406 Punjab India Intelligent Material Pvt. Ltd. (Nanoshel LLC) Derabassi-140507 Punjab India Department of Mechanical Engineering National University of Singapore Singapore 117576 Singapore

Graphene is a fascinating material of recent origin whose first isolation was being made possible through micromechanical cleavage of a graphite crystal. Owing to its fascinating properties, graphene has garnered significant attention in the research community for multiple applications. A number of methods have been employed for the synthesis of single-layer and multi-layer graphene. The extraordinary properties of graphene such as its Hall effect at room temperature, high surface area, tunable bandgap, high charge mobility and excellent electrical, conducting and thermal properties allow for the development of sensors of various types and also opened the doors for its use in nanoelectronics, supercapacitors and batteries. Biological aspects of graphene have also been investigated with particular emphasis on its toxicity and drug delivery. In this review, many of the salient aspects of graphene, such as from synthesis to its applications, primarily focusing on sensor applications which are of current interest, are covered.

关键词： graphene nanoelectronics Hall effect tunable bandgap supercapacitors sensors catalysis

Posterior segment nucleotomy for dislocated sclerotic cataractous lens using chandelier endoilluminator and sharp tipped chopper

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International Journal of Ophthalmology(English edition) 2015年第4期8卷 833-834页

作者： Brijesh Takkar Rajvardhan Azad Shorya Azad Anubha rathi Dr.Rajendra Prasad Centre for Ophthalmic Sciences All India Institute of Medical Sciences

· AIM: To describe a new surgical technique for managing dislocated sclerotic cataractous lens.· METHODS: Six patients with advanced posteriorly dislocated cataracts were operated at a tertiary care centre and analyzed retrospectively. After standard 3 port23 G pars plana vitrectomy and perfluorocarbon liquid(PFCL) injection, the dislocated white cataract was held with occlusion using phaco fragmatome and then chopped into smaller pieces with a sharp tipped chopper using 25 G chandelier endoilluminator. Each piece was emulsified individually. Following aspiration of PFCL,Fluid Air Exchange was done in all the cases and surgery completed uneventfully.·RESULTS: Best corrected visual acuity(BCVA) in all the patients was better than 6/12 after one month of follow up. No serious complications were noted till minimum 6mo of follow up.·CONCLUSION: Four port posterior segment nucleotomy with a chandelier endoilluminator, fragmatome and a chopper appears to be a safe, easy and effective procedure for managing dislocated sclerotic cataractous nuclei. Ultrasonic energy used and adverse thermal effects of the fragmatome on the sclera may be lesser.

关键词： posterior segment nucleotomy intravitreal nucleotomy dislocated sclerotic lens dislocated hard lens dislocated lens complications of phacoemulsification

Optimal integration of battery energy-storage system with high penetration of renewable energy in radial distribution network

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Clean Energy 2022年第3期6卷 404-411页

作者： Hafsa Imra Sheikh Mahesh Kumar rathi Amir Mahmood Soomro Department of Electrical Engineering Mehran University of Engineering and TechnologyJamshoroPakistan

Considering the intermittent nature of renewable energy,a storage system to reserve power in off-peak hours and then to supply it during peak hours is ***,if these storage devices in a network are not placed in an appropriate manner,the advantages can never be *** this study,the allocation and sizing strategies of a battery energy-storage system(BESS)in an optimal way are proposed to improve the performance of the radial distribution *** test network adopted is a standard IEEE 33 bus network that is integrated with solar *** are carried out in DIgSILENT PowerFactory for the distribution network model and the process of optimization is done through MATLAB®.The optimization algorithm adopted is the genetic *** system is studied for 24 hours with a step size of 15 minutes,employing a time-sweep analysis of dynamic *** is studied under three different scenarios and the results are *** results illustrate a considerable reduction in power losses in the case of the optimized *** total losses before the optimization process are 16365.57 *** total losses after the employment of the proposed solution are 10246.5 kW,which means that the losses are reduced by≤62%.

关键词： energy and environment energy storage solar

The use of hydrogel-delivered extracellular vesicles in recovery of motor function in stroke:a testable experimental hypothesis for clinical translation including behavioral and neuroimaging assessment approaches

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Neural Regeneration Research 2021年第4期16卷 605-613页

作者： Magdalini Tsintou Kyriakos Dalamagkas Tara LMoore Yogesh rathi Marek Kubicki Douglas LRosene Nikos Makris Departments of Psychiatry and Neurology Services Center for Neural Systems InvestigationsCenter for Morphometric AnalysisAthinoula A.Martinos Center for Biomedical ImagingMassachusetts General HospitalHarvard Medical SchoolBostonMAUSA Department of Psychiatry Psychiatry Neuroimaging LaboratoryBrigham and Women’s HospitalHarvard Medical SchoolBostonMAUSA University College of London Division of Surgery&Interventional Science Center for Nanotechnology&Regenerative MedicineUniversity College LondonLondonUK Department of Physical Medicine and Rehabilitation The University of Texas Health Science Center at HoustonHoustonTXUSA The Institute for Rehabilitation and Research Memorial Hermann Research Center The Institute for Rehabilitation and Research Memorial Hermann HospitalHoustonTXUSA Department of Anatomy&Neurobiology Boston University School of MedicineBostonMAUSA

Neural tissue engineering,nanotechnology and neuroregeneration are diverse biomedical disciplines that have been working together in recent decades to solve the complex problems linked to central nervous system(CNS)*** is known that the CNS demonstrates a very limited regenerative capacity because of a microenvironment that impedes effective regenerative processes,making development of CNS therapeutics *** the high prevalence of CNS conditions such as stroke that damage the brain and place a severe burden on afflicted individuals and on society,it is of utmost significance to explore the optimum methodologies for finding treatments that could be applied to humans for restoration of function to pre-injury *** vesicles(EVs),also known as exosomes,when derived from mesenchymal stem cells,are one of the most promising approaches that have been attempted thus far,as EVs deliver factors that stimulate recovery by acting at the nanoscale level on intercellular communication while avoiding the risks linked to stem cell *** the same time,advances in tissue engineering and regenerative medicine have offered the potential of using hydrogels as bio-scaffolds in order to provide the stroma required for neural repair to occur,as well as the release of biomolecules facilitating or inducing the reparative *** review introduces a novel experimental hypothesis regarding the benefits that could be offered if EVs were to be combined with biocompatible injectable *** rationale behind this hypothesis is presented,analyzing how a hydrogel might prolong the retention of EVs and maximize the localized benefit to the *** sustained delivery of EVs would be coupled with essential guidance cues and structural support from the hydrogel until neural tissue remodeling and regeneration ***,the importance of including nonhuman primate models in the clinical translation pipeline,as well as the added benefit of m

关键词： cortical injury exosomes extracellular vesicles hydrogels neural tissue engineering neural tissue repair neuroregeneration non-human primates stroke

Evaluation of pedestrian mid-block road crossing behaviour using artificial neural network

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Journal of Traffic and Transportation Engineering(English Edition) 2014年第2期1卷 111-119页

作者： B Raghuram Kadali Nivedan rathi Vedagiri Perumal Department of Civil Engineering Indian Institute of Technology Bombay

Pedestrians usually cross the road at mid-block locations in India because of the ease and convenience to reach their destination as compared to intersection locations. It is important to evaluate the pedestrian gap acceptance behavior at mid-block locations because of inadequate vehicular gaps un- der mixed traffic condition, which translates into the pedestrian road crossing behavior. The present study examines the pedestrian gap acceptance behaviour by employing an artificial neural network （ANN） model for understanding the decision making process of pedestrians, i. e. , acceptance or rejec- tion of vehicular gaps at a mid-block location. From the results it has been found that the pedestrian rolling gap, frequency of attempt, vehicular gap size, pedestrian speed change condition and vehicle speed have major role in pedestrian gap acceptance. These results can lead to a better design of pedestrian crossing facilities where adequate gaps are not available in vehicular flow at mid-block crosswalk locations.

关键词： pedestrian mid-block artificial neural network rolling gap gap acceptance behavior

Population Structure and Marker-Trait Association in Indigenous Aromatic Rice

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Rice science 2017年第3期24卷 145-154页

作者： Preeti Rekha TALUKDAR Sunayana rathi Khanin PATHAK Sanjay Kumar CHETIA Ramendra Nath SARMA Department of Plant Breeding and Genetics Assam Agricultural University Jorhat 785013 India Biochemistry & Agricultural Chemistry Assam Agricultural University Jorhat 785013 India Regional Agricultural Research Station Assam Agricutural University Jorhat 785013 India

Joha rice of Assam is a class of rice with aroma, good cooking qualities and excellent palatability, which are grown in different places of Assam with their adaptability to local situations. A total of 143 simple sequence repeat markers were used in this study to reveal sufficient genetic variations among the 40 Joha and 14 non-Joha rice genotypes. Polymorphism information content of these markers were from 0.17 to 0.88, where the average of 3.7 alleles were observed. The model-based population assignment and dendrogram analysis identified three distinct groups in the 54 rice accessions, which established a clear identity of Joha accessions from the Basmati accessions, indicating high diversity and strong population structure in Joha rice. Furthermore, a total of 29 significant marker-trait associations(P < 0.05) for 10 characters were detected. The QTLs related with yield and grain quality can be used effectively in crop improvement programs and for further fine mapping and validation of specific genes to develop gene-based perfect markers in rice breeding and for mining of better alleles of these genes in Joha rice collections.

关键词： Joha rice genetic diversity association mapping population structure quantitative trait locus aroma

Intelligent Computational Model for Energy Efficiency and AI Automation of Network Devices in 5G Communication Environment

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Tsinghua Science and Technology 2024年第6期29卷 1728-1751页

作者： Ashish Bagwari Jaganathan Logeshwaran M.Raja P.Devisivasankari Jyotshana Bagwari Vikas rathi Asma Mohammed Elbashir Saad Department of Electronics and Communication Engineering Uttarakhand Technical UniversityDehradun 248007India Department of Electronics and Communication Engineering Sri Eshwar College of EngineeringCoimbatore 641202India Department of Computer Science and Engineering CMR Institute of TechnologyKarnataka 560037India Department of Information Science and Engineering CMR Institute of TechnologyKarnataka 560037India Advanced and Innovative Research Laboratory Dehradun 248001India Department of Electronics and Communication Engineering Graphic Era(Deemed to be University)Dehradun 248007India Department of Physics College of Science and HumanitiesPrince Sattam Bin Abdulaziz UniversityAl-Kharj 16273Saudi Arabia

Currently, the 4G network service has caused massive digital growth in high use. Video calling has become the go-to Internet application for many people, downloading even huge files in minutes. Everyone is looking for and buying only 4G Subscriber Identity Module (SIM)-capable mobiles. In this case, the expectation of 5G has increased in line with 2G, 3G, and 4G, where the G stands for generation, and it does not indicate Internet or Internet speed. 5G includes next-generation features that are more advanced than those available in 4G network services. The main objective of 5G is uninterrupted telecommunication service in hybrid energy storage system. This paper proposes an intelligent networking model to obtain the maximum energy efficiency and Artificial Intelligence (AI) automation of 5G networks. There is currently an issue where the signal cuts out when crossing an area with one tower and traveling to an area with another tower. The problem of “call drop”, where the call is disconnected while talking, is not present in 5G. The proposed Intelligent Computational Model (ICM) model obtained 96.31% network speed management, 90.63% battery capacity management, 92.27% network device management, 93.57% energy efficiency, and 88.41% AI automation.

关键词： hybrid energy storage system 4G digital growth 5G downloading Subscriber Identity Module(SIM) generation network energy efficiency Artificial Intelligence(Al)automation

Cellulose based polymers in development of amorphous solid dispersions

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Asian Journal of Pharmaceutical Sciences 2019年第3期14卷 248-264页

作者： Rahul B Chavan Sneha rathi Vaskuri G S Sainaga Jyothi Nalini R Shastri Solid State Pharmaceutical Research Group(SSPRG) Department of Pharmaceutics National Institute of Pharmaceutical Education and Research

Cellulose derivatives have gained immense popularity as stabilizers for amorphous solid dispersion owing to their diverse physicochemical properties. More than 20 amorphous solid dispersion-based products that have been approved for marketing consist of cellulose derivatives as stabilizers, thus highlighting their importance in generation of amorphous solid dispersions. These polymers offer numerous advantages like drug solubilization, crystallization inhibition and improvement in release patterns of drugs. Exploring their potential and exploiting their chemistry and p H responsive behaviour have led to the synthesis of new derivatives that has broadened the scope of the use of cellulose derivatives in amorphous formulation development. The present review aims to provide an overview of different mechanisms by which these cellulose derivatives inhibit the crystallization of drugs in the solid state and from supersaturated solution. A summary of different categories of cellulose derivatives along with the newly explored polymers has been provided. A special segment on strengths, weaknesses, opportunities, and threats(SWOT) analysis and critical quality attributes(CQAs) which affect the performance of the cellulose based amorphous solid dispersion will aid the researchers in identifying the major challenges in the development of cellulose based solid dispersion and serve as a guide for further formulation development.

关键词： Supersaturation HPMC Amorphous form Crystallization Polymers

Spontaneous rupture of the renal pelvis presenting as an urinoma in locally advanced rectal cancer

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World Journal of Clinical Cases 2014年第4期2卷 108-110页

作者： Pankaj Kumar Garg Debajyoti Mohanty Vinita rathi Bhupendra Kumar Jain Department of Surgery University College of Medical Sciences and Guru Teg Bahadur Hospital Department of Surgical Oncology All India Institute of Medical Sciences Department of Radiology University College of Medical Sciences and Guru Teg Bahadur Hospital

A 29-year-old gentleman underwent a transverse colostomy for intestinal obstruction caused by advanced rectal carcinoma. On the 5th postoperative day, the patient developed a painful swelling on the right side of the abdomen. The contrast enhanced computed tomography of the abdomen revealed a right sided hydronephrosis, a large rent in the renal pelvis, and a large retroperitoneal fluid collection on the right side. Percutaneous nephrostomy and pigtail catheter drainage of the urinoma led to resolution of abdominal swelling. Development of a urinoma as a consequence of rectal carcinoma is highly unusual. Prompt imaging for confirmation of diagnosis, decompression of the renal pelvicalyceal system, and drainage of the urinoma limits morbidity.

关键词： Colorectal cancer Urinoma Spontaneous rupture of the renal pelvis Percutaneous nephrostomy Pigtail catheter drainage