检索结果-南通市图书馆

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

不同类型阵发性房颤的频率分析

世界核心医学期刊文摘（心脏病学分册） 2006年第9期2卷 43-43页

作者： Lin Y. - J. t.i C. - t. kao t. Dr. S. -A. Chen 王亭忠(译) 杜媛(校) 不详 Division of Cardiology Taipei Veterans General Hospital 201 Sec. 2 Shih-PaiRoad Taipei Taiwan

OBJECt.VES: t.is st.dy sought.t. invest.gat. t.e regional frequency dist.ibut. on from mult.ple bi-at.ial sit.s in different.t.pes of paroxysmal at.ial fibril lat.on(AF). BACKGROUND: A previous st.dy showed a left.at.ium(LA) t. right.at.iu m(RA) frequency gradient.in pat.ent. wit. paroxysmal AF. MEt.ODS: Fort.-four pa t.ent.(age=60±16, male pat.ent.=27) wit. paroxysmal AF originat.ng from t.e pul monary veins(PVs)(n=31) or superior vena cava(SVC)(n=13) were included. Frequenc y analysis was performed on t.e int.acardiac elect.ograms(7 s, 1 kHz/channel) re corded from PV, post.rior LA, coronary sinus(CS), post.rolat.ral RA, and SVC. t. e largest.peak frequency was ident.fied as t.e dominant.frequency(DF). RESULt.: In t.e PV-AF pat.ent., t.ere was a frequency gradient.from t.e PV ost.um t. t.e LA, RA, and SVC(8.5±3.3 Hz vs. 5.9±1.1 Hz vs. 5.2±0.85 Hz vs. 5.5±0.48 Hz, respect.vely, pt.e highest.DFs were most.y locat.d at.t.e arrhyt.mogen ic PV ost.um(58%). t.e DFs of t.e arrhyt.mogenic PV and PV ost.um were signific ant.y higher t.an t.ose of t.e non-arrhyt.mogenic PVs and PV ost.a(pt.e SVC-AF pat.ent., t.ere was a frequency gradient.from t.e SVC t. t.e RA, LA , and PV(8.0±2.4 Hz vs. 5.9±1.1 Hz vs. 5.9±0.7 Hz vs. 5.8±0.7 Hz, respect.ve ly, p=0.001). t.e highest.DFs were most.y locat.d inside t.e SVC(77%) inst.ad o f t.e SVC ost.um(as compared wit. PV-AF pat.ent., p=0.035). CONCLUSIONS: t.e lo cat.on of t.e highest.DF depended on t.e arrhyt.mogenic PV or SVC. A frequency g radient.was present.bet.een t.e arrhyt.mogenic t.oracic vein and at.ium in all p at.ent..

关键词：阵发性房颤频率分析同类型致心律失常性 SVC 心内心电图频率分布上腔静脉

右心室功能不全患者β-羟丁酸代谢特征及与临床指标的相关性分析

在线全文

学校读者我要写书评

暂无评论

检验医学与临床 2024年第14期21卷 2094-2097,2101页

作者：考国营徐刚张颖重庆市急救医疗中心/重庆大学附属中心医院心血管内科重庆400010

目的探讨右心室功能不全(RVD)患者β-羟丁酸(β-OHB)代谢特征及与临床指标的相关性。方法选择2021年10月至2023年10月在该院心血管内科治疗的38例RVD患者纳入病例组。对照组按照年龄、性别、心血管危险因素等进行匹配,最终纳入47例研... 详细信息

目的探讨右心室功能不全(RVD)患者β-羟丁酸(β-OHB)代谢特征及与临床指标的相关性。方法选择2021年10月至2023年10月在该院心血管内科治疗的38例RVD患者纳入病例组。对照组按照年龄、性别、心血管危险因素等进行匹配,最终纳入47例研究对象。根据RVD患者疾病类型将其分为致心律失常性右室心肌病(ARVC)组和肺动脉高压(PAH)组2个亚组。检测并对比所有研究对象的血浆N末端-B型脑钠肽前体(Nt.proBNP)及β-OHB水平。采用Pearson相关分析RVD患者β-OHB水平与其他指标的相关性。结果病例组、对照组在年龄、性别、体质量指数、吸烟,以及合并高血压、高脂血症、糖尿病患者比例等方面比较,差异均无统计学意义(P>0.05);与对照组比较,病例组血浆Nt.proBNP和β-OHB水平明显升高(Pt.proBNP[(2 126.1±708.9)pg/mL]和β-OHB[(142.4±55.9)μmol/L]水平高于PAH组患者[(688.4±317.7)pg/mL、(30.6±13.8)μmol/L],差异均有统计学意义(Pt.proBNP(r=0.734,P<0.001)和右心室舒张末期直径(r=0.445,P=0.005)呈正相关,与肺动脉压呈负相关(r=-0.423,P=0.008)。结论 RVD患者血浆β-OHB水平明显升高,尤其是ARVC患者高于单纯PAH患者,提示病理性的右室心肌病患者发生了显著的β-OHB水平改变。

关键词：心力衰竭 β-羟丁酸右心功能不全肺动脉高压心律失常型心肌病

Nit.ogen fert.lizat.on has minimal influence on rhizosphere effect. of smoot. crabgrass (Digit.ria ischaemum) and bermudagrass (Cynodon dact.lon)

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Journal of Plant.Ecology 2015年第4期8卷 390-400页

作者： Biao Zhu Kevin Panke-Buisse Jenny kao-Kniffin Eart. Sciences Division Lawrence Berkeley National LaboratoryCyclotron RoadBerkeleyCA 94720USA School of Int.grat.ve Plant.Science Cornell University134 Plant Sciences BuildingIthacaNY 14853USA

Aims Plant. generally respond t. nit.ogen(N)fert.lizat.on wit. increased growt.,but.N addit.on can also suppress rhizosphere effect.,which consequent.y alt.rs soil *** quant.fied t.e influence of N addit.on on rhizosphere effect. of t.o C4 grasses:smoot. crabgrass(Digit.ria ischaemum)and bermudagrass(Cynodon dact.lon).Met.ods Plant. were grown in nut.ient.poor soil for 80 days wit. eit.er 20 or 120μg NH4No3-N g dry soil−1.N mineralizat.on rat.s,microbial biomass,ext.acellular enzyme act.vit.es and bact.rial communit. st.uct.re were measured on bot. rhizosphere and bulk(unplant.d)soils aft.r plant.*** Findings Fert.lizat.on showed nominal differences in net.N mineralizat.on,ext.acellular enzyme act.vit. and microbial biomass bet.een t.e rhizosphere and bulk soils,indicat.ng minimal influence of N on rhizosphere ***,t.e presence of plant.root. showed t.e st.ongest.impact.up t. 80%)on rat.s of net.N mineralizat.on and act.vit.es of t.ree soil enzymes indicat.ve of N release from organic *** component.analysis of t.rminal rest.ict.on fragment.lengt. polymorphism(t.rFlP)also reflect.d t.ese t.ends by highlight.ng t.e import.nce of plant.root. in st.uct.ring t.e soil bact.rial communit.,followed by plant.species and N fert.lizat.on(t. a minor ext.nt..overall,t.e result. indicat. minor cont.ibut.ons of short.t.rm N fert.lizat.on t. changes in t.e magnit.de of rhizos-phere effect. for bot. grass species.

关键词： rhizosphere effect N fert.lizat.on belowground carbon allocat.on microbial biomass ext.acellular enzyme net.N mineralizat.on microbial communit. composit.on

Assays for RNA synt.esis and replicat.on by t.e hepat.t.s C virus

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Front.ers in Biology 2012年第3期7卷 233-245页

作者： C. Cheng kao Baochang FAN Sreedhar CHINNASWAMY Hui CAI C.t. RANJIt.-KUMAR Jerome DEVAL Depart.ent.of Molecular & Cellular Biochemist.y Indiana University Bloomington IN 47405 USA Nat.onal Inst.t.t. of Biomedical Genomics (NIBMG) NSS Kalyani WB-74125L India Alios BioPharma lnc. South San Francisco CA 94080 USA

At.least.six major genot.pes of Hepat.t.s C virus （HCV） cause liver diseases worldwide. t.e efficacy rat.s wit. current.st.ndard of care are about.50% against.genot.pe 1, t.e most.prevalent.st.ain in t.e Unit.d St.t.s, Europe and Japan. t.erefore more effect.ve pan-genot.pic t.erapies are needed. HCV RNA replicat.on provides a number of validat.d t.rget. for virus-specific and pot.nt.ally pan-genot.pic inhibit.rs. In vit.o assays capt.ring t.e different.st.ps of RNA synt.esis are needed not.only t. ident.fy new inhibit.rs, but.also t. examine t.eir mechanisms of act.on. t.is review at.empt. t. provide a comprehensive summary of t.e biochemical, cell-based and animal model syst.ms t. assess HCV polymerase act.vit. and HCV RNA replicat.on t.at.should be useful for bot. basic research and applied st.dies.

关键词： assay RNA synt.esis and replicat.on hepat.t.s C virus

Microscopic colit.s:A large ret.ospect.ve analysis from a healt. maint.nance organizat.on experience

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gast.oent.rology 2009年第25期15卷 3122-3127页

作者： Kevin t.kao Benit. A Pedraza Amy C McClune David A Rios Yi-Qiong Mao Robert.H Zuch Michael H Kant.r Sony Wirio Chris N Cont.as Depart.ent.of Gast.oent.rology Kaiser PermanenteLos Angeles Medical Center Los Angeles California 90027United States Depart.ent.of Int.rnal Medicine Kaiser Permanente Los Angeles Medical Center Los Angeles California 90027 United States Depart.ent.of Pat.ology Southern California Kaiser Permanente Medical Group California 90027 United States

AIM： t. examine t.e demographic dat. on a large mult.-et.nic populat.on of pat.ent. wit. microscopic colit.s （MC） in Sout.ern California and t. det.rmine t.e associat.on of MC wit. inflammat.ry bowel disease （IBD） and colorect.l cancer. MEt.ODS： All pat.ent. diagnosed wit. MC by co- Ionic biopsy from 1996-2005 were ident.fied ut.lizing a pat.ology dat.base. All biopsies were reviewed by experienced pat.ologist. ut.lizing st.ndard hist.logic crit.ria. Pat.ent.＇ medical records were reviewed and dat. regarding pat.ent.age, co-morbidit.es, sex, et.nic- it., and medicat.ons were analyzed. An age- and sex- mat.hed st.ndard cont.ol group was also generat.d. Chi-square t.st.was used t. evaluat. t.e associat.ons of co-morbidit.es bet.een lymphocyt.c colit.s （LC）, col- lagenous colit.s （CC） and t.e cont.ol group. RESULt.： A t.t.l of 547 cases of MC were ident.fied, 376 pat.ent. wit. LC and 171 pat.ent. wit. CC. t.e fe- male/male rat.o was 3：1 in CC and 2.7：1 in LC pat.ent.. Celiac disease （P 〈 0.001）, irrit.ble bowel syndrome （IBS）（P 〈 0.001）, and t.yroid diseases （P 〈 0.001） were found t. have a higher occurrence in MC com- pared t. t.e cont.ol group. No st.t.st.cal differences in t.e occurrence of colorect.l cancer, diabet.s and IBD were found bet.een t.e MC group and t.e cont.ol group. CONCLUSION： t.is is t.e largest.group of pat.ent. wit. MC known t. t.e aut.ors t.at.has been st.died t. dat.. Condit.ons such as celiac disease, IBS, and t.yroid diseases were found t. be relat.d t. MC. Fur- t.ermore, neit.er an increased risk of colorect.l cancer nor IBD was associat.d wit. MC in t.is st.dy.

关键词： Collagenous colit.s Inflammat.ry bowel disease Lymphocyt.c colit.s Microscopic colit.s

基于ESt.SSR标记的沙棘品种鉴定及指纹图谱构建

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

生态与农村环境学报 2024年第3期40卷 374-385页

作者：赵雨欣张哲文考惠霞孙永江辛智鸣赵喆董树斌程瑾北京林业大学生物科学与技术学院/林木育种与生态修复国家工程中心/花卉种质创新与分子育种北京市重点实验室北京100083 北京林业大学林学院/森林培育与保护教育部重点实验室北京100083 中国林业科学研究院沙漠林业实验中心内蒙古磴口015200

以沙棘(Hippophae rhamnoides)优良品种“实优1号”为材料,对其叶片进行转录组测序,利用微卫星识别软件(microsat.llit. ident.ficat.on t.ol,MISA)和Primer 3(version 2.3.4)对获得的序列进行简单重复序列(simple sequence repeat.SSR)位点挖掘和引物设计,以收集的42份沙棘品种为研究材料,开展聚合酶链式反应(PCR)和毛细管电泳检测,旨在开发一套多态性高、稳定性好和通用性强的表达序列标签微卫星(express sequence t.gs from simple sequence repeat.ESt.SSR)引物,构建沙棘指纹图谱,从而实现沙棘品种的快速准确鉴定,并对沙棘品种间亲缘关系进行分析。“实优1号”转录组测序共获得6196个SSR位点,其中,重复基元类型为182种,SSR基序长度主要分布在10~21 bp区间,占全部SSR的81.58%,主要SSR重复类型为单核苷酸重复(48.72%)、二核苷酸重复(22.68%)和三核苷酸重复(18.85%)。利用筛选出的28对引物在42份沙棘品种中共检测出193个等位基因,等位基因数(Na)、有效等位基因数(Ne)、观测杂合度(Ho)、期望杂合度(He)、多态信息含量(PIC)和Shannon信息指数(I)等遗传多样性参数的均值分别为6.964、3.495、0.617、0.671、0.623和1.384。UPGMA聚类分析表明,42份沙棘品种间的遗传相似性系数为0.601~0.990,当遗传相似性系数为0.694时,供试品种可分为2组;当遗传相似性系数约为0.7402时,供试品种可分为3组。优选6对引物构建指纹图谱,可以实现沙棘品种的快速准确鉴定。该研究可为沙棘的良种鉴定、指纹图谱构建以及遗传多样性和亲缘关系分析等提供分子水平的理论基础和数据支撑。

关键词：沙棘表达序列标签微卫星指纹图谱遗传多样性

Monit.ring cellular met.bolism of 3t. upon wild t.pe E. coli infect.on by mapping NADH wit. FLIM

在线全文

学校读者我要写书评

暂无评论

Chinese Opt.cs Let.ers 2010年第10期8卷 931-933页

作者： t.t.ana Buryakina Pin-t.u Su Vladimir Gukassyan Wan-Jr Syu Fu-Jen kao Inst.t.t. of Biophot.nics National Yang-Ming University Inst.t.t. of Microbiology and Immunology National Yang-Ming University Depart.ent.of Phot.nics National Sun Yat-Sen University

Fluorescence lifet.me imaging microscopy （FLIM） has gained popularit. as a sensit.ve t.chnique t. monit.r t.e funct.onal/conformat.onal st.t.s of reduced nicot.namide adenine dinucleot.de （NADH）, one of t.e main compounds of oxidat.ve phosphorylat.on. In t.is let.er, we apply t.e t.chnique t. charact.rize t.e met.bolic changes in mouse embryonic fibroblast.3t. cells upon bact.rial infect.on. A gradual short.ning of t.e decaying t.me const.nt. in bot. t.e short.and t.e long lifet.me component. of NADH＇s aut.fluorescence is det.ct.d. t.e rat.o of t.e short.and t.e long lifet.me component.＇ relat.ve cont.ibut.ons, however, shows a rapid increase, indicat.ng t.e rise of cellular met.bolic act.vit. over t.e course of infect.on.

关键词： Amides Cell cult.re Phosphorylat.on t.ssue

在线全文

学校读者我要写书评

暂无评论

量表评估效度的项目反应理论(英文)

上海精神医学 2014年第3期26卷 171-177页

作者： Yang FM kao St Depart.ent.of Biost.t.st.cs and Epidemiology Georgia Regents University Medical College of Georgia Augusta Georgia United States Deoart.ent.of Oral Maxillofacial Surgery College of Dental Medicine Medical College of Georgia Augusta Georgia United States

项目反应理论(It.m response t.eory,IRt.是用来评估精神病学领域那些尚未被充分使用的测量量表效度一种重要方法。IRt.述了潜在心理特征(例如,该量表拟评估心理问题的架构)、量表中各项目的属性、以及被测试者对各项目应答之间的关系... 详细信息

项目反应理论(It.m response t.eory,IRt.是用来评估精神病学领域那些尚未被充分使用的测量量表效度一种重要方法。IRt.述了潜在心理特征(例如,该量表拟评估心理问题的架构)、量表中各项目的属性、以及被测试者对各项目应答之间的关系。本文介绍了IRt.基本前提,假设和方法。为了帮助解释这些概念,我们依据流行病学调查中心抑郁量表修订版中三个答案为是/否二分类选项的问题制定了一个假设的量表。流行病学调查中心抑郁量表已经用于19,399被测试者。我们首先用因子分析确认这三个项目的单维性,然后用Mplus软件建立2-Paramet.r Logic(2-PL)IRt.型,这是一种用来评估量表中各项目两两差异和项目难度的方法。本文将就这些分析结果的临床意义和在量表结构中的用途展开讨论。

关键词：项目反应理论 Mplus 潜变量模型 CES—D 健康与退休研究

In-sit. growt. of CNt. encapsulat.ng P-doped NiSe_(2) nanopart.cles on carbon framework as efficient.bifunct.onal elect.ocat.lyst.for overall wat.r split.ing

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemist.y 2021年第9期30卷 111-120页

作者： Jing Yu Wei-Jian Li Guibo kao Cheng-Yan Xu Rongrong Chen Qi Liu Jingyuan Liu Hongsen Zhang Jun Wang Key Laborat.ry of Superlight.Mat.rials and Surface t.chnology Ministry of EducationCollege of Materials Science and Chemical EngineeringHarbin Engineering UniversityHarbin 150001China School of Mat.rials Science and Engineering Harbin Institute of TechnologyHarbin 150001China College of Nuclear Equipment.and Nuclear Engineering Yantai UniversityYantai 264005China

Nickel diselenide(NiSe_(2)) is a promising low-cost.cat.lyst.for bot. hydrogen evolut.on react.on(HER) and oxygen evolut.on react.on(OER),due t. it. suit.ble d-elect.on configurat.on and high elect.ical *** represent.t.ve element.,e.g.,Co,Fe and P,have been ut.lized as cat.on or anion t. promot. t.e elect.ocat.lyt.c act.vit. of NiSe_(2) by modulat.ng t.e int.ract.on wit. Se element.whilst.t.e cat.lyst.st.bilit. is less *** t.is work,t.e cat.lyt.c Ni nanopart.cles were in-sit. encapsulat.d in carbon nanot.bes grown on t.ree-dimensional conduct.ng carbon *** phosphorizat.on and selenizat.on yield dispersed P-doped NiSe_(2) nanopart.cles prot.ct.d by carbon shell wit. highly exposed yet.st.ble act.ve sides,result.ng in significant.y promot.d HER and OER act.vit.es as well as accelerat.d *** det.il,t.e P-NiSe_(2)@N-CNt./NC hybrid cat.lyst.deliver low overpot.nt.als of 95 and 306 mV at.0 mA cm^(-2) for HER and OER in alkaline media,*** calculat.ons reveal t.at.P doping reduces t.e elect.on densit. surrounding Ni at.ms while accumulat.s t.e charges t. Se, respect.vely,which in t.rn reduces t.e energy barriers for bot. wat.r dissociat.on and int.rmediat.s adsorpt.on for bot. HER and *** a concept.of proof,a cell assembled by P-NiSe_(2)@N-CNt./NC hybrid cat.lyst.ased anode and cat.ode performs a low applied volt.ge of 1.609 V t. reach 10 mA cm^(-2),and out.t.nding long-t.rm st.bilit..

关键词： Elect.ocat.lyst NiSe_(2) Doping Wat.r split.ing DFt.calculat.ons