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Reliability assessment for serviceability limit states of stiffened deep cement mixing column-supported embankments

Journal of Rock Mechanics and Geotechnical Engineering 2023年第9期15卷 2402-2422页

作者： Chana Phutthananon Pornkasem Jongpradist kangwan kandavorawong Daniel Dias Xiangfeng Guo Pitthaya Jamsawang Construction Innovations and Future Infrastructures Research Center Department of Civil EngineeringFaculty of EngineeringKing Mongkut’s University of Technology ThonburiBangkok10140Thailand Laboratory 3SR Grenoble INPCNRSGrenoble Alpes UniversityGrenoble38000France Department of Civil and Environmental Engineering National University of SingaporeSingapore119077Singapore Soil Engineering Research Center Department of Civil EngineeringKing Mongkut’s University of Technology North BangkokBangkok10800Thailand

The reliability and deterministic analyses of wood-cored stiffened deep cement mixing and deep cement mixing column-supported embankments(referred to as WSCSE and DCSE,respectively)considering serviceability limit state requirements are presented in this *** field theory was used to simulate the spatial variability of soilcement mixing(SCM)material in which the adaptive Kriging Monte Carlo simulation was adopted to estimate the failure probability of a columnsupported embankment(CSE)system.A new method for stochastically generating random values of unconfined compressive strength(qu)and the ratio(Ru)between the undrained elastic modulus and qu of SCM material based on statistical correlation data is *** performance of CSEs concerning changes in the mean(μ),coefficient of variation(CoV),and vertical spatial correlation length(θv)of qu and Ru are presented and *** obtained results indicate that WSCSE can provide a significantly higher reliability level and can tolerate more SCM material spatial variability than *** performance of DCSE and WSCSE,which can be considered satisfactory in a deterministic framework,cannot guarantee an acceptable reliability level from a probabilistic *** highlights the importance and necessity of employing reliability analyses for the design of ***,consideration of only μ and CoV of qu seems to be sufficient for reliability analysis of WSCSE while for DCSE,uncertainties regarding the Ru(*** μ and CoV)and θv of qu cannot be ignored.

关键词： Reliability analysis Column-supported embankment(CSE) Stiffened deep cement mixing column Serviceability Adaptive kriging Monte Carlo simulation

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Non-microbial approach for Helicobacter pylori as faster track to prevent gastric cancer than simple eradication

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World Journal of Gastroenterology 2013年第47期19卷 8986-8995页

作者： Sang-Ho Park Napapan kangwan Jong-Min Park Eun-Hee Kim Ki Baik Hahm CHA Cancer Prevention Research Center CHA Cancer InstituteCHA UniversitySeoul 135-081South Korea

Although the International Agency for Research on Cancer declared Helicobacter pylori(***)as a definite human carcinogen in 1994,the Japanese Society for Helicobacter Research only recently(February 2013)adopted the position that *** infection should be considered as an indication for either amelioration of chronic gastritis or for decreasing gastric cancer *** researchers have found that *** eradication halts progressive mucosal damage and that successful eradication in patients with non-atrophic gastritis most likely prevents subsequent development of gastric ***,those who have already developed atrophic gastritis/gastric atrophy retain potential risk factors for gastric *** chronic perpetuated progression of ***-associated gastric inflammation is associated with increased morbidity culminating in gastric carcinogenesis,a non-microbial approach to treatment that provides long-term control of gastric inflammation through nutrients and other interventions may be an effective way to decrease this *** non-microbial approach might represent a new form of prerequisite"rescue"therapy that provides a quicker path to the prevention of gastric cancer as compared to simple eradication.

关键词： Helicobacter pylori Gastric cancer Prevention Atrophic gastritis Non-microbial approach

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红曲米致横纹肌溶解症2例

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药物不良反应杂志 2023年第5期25卷 315-317页

作者：徒康宛朱银芳汤勤周敏付德才徐淑凡杜凡凡苏麒麟无锡市第五人民医院中西医结合科无锡214000

2例患者(例1男,61岁;例2女,58岁)均因血脂异常使用红曲米6 g口服、1次/d。例1有血吸虫性肝硬化、胆汁淤积性肝炎,三酰甘油5.32 mmol/L,口服红曲米26 d后出现四肢无力、肌酸激酶(CK)604 U/L。立即停用红曲米,3 d后患者出现下肢肌肉酸痛,C... 详细信息

2例患者(例1男,61岁;例2女,58岁)均因血脂异常使用红曲米6 g口服、1次/d。例1有血吸虫性肝硬化、胆汁淤积性肝炎,三酰甘油5.32 mmol/L,口服红曲米26 d后出现四肢无力、肌酸激酶(CK)604 U/L。立即停用红曲米,3 d后患者出现下肢肌肉酸痛,CK最高达117748 U/L,经地塞米松、补液水化治疗12 d后上述症状逐渐消失,CK 79 U/L。例2为急性肝炎患者,三酰甘油2.34 mmol/L,口服红曲米24 d后出现双下肢乏力、肌肉酸痛,CK最高达52222 U/L。立即停用红曲米,予甲泼尼龙、补液水化等治疗12 d后病情好转,CK 210 U/L。

关键词：高脂血症横纹肌溶解红曲米高甘油三酯血症

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Quality of healing of gastric ulcers: Natural products beyond acid suppression

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World Journal of Gastrointestinal Pathophysiology 2014年第1期5卷 40-47页

作者： Napapan kangwan Jong-Min Park Eun-Hee Kim Ki Baik Hahm CHA Cancer Prevention Research Center CHA Cancer InstituteCHA University College of Pharmacy CHA University Department of Gastroenterology CHA University Bundang Medical Center

Gastric ulcer is a chronic disease featured with unexpected complications, including bleeding, stenosis and perforation, as well as a high incidence of recurrence. Clinical treatments for gastric ulcer have allowed the rapid development of potent anti-ulcer drugs during the last several decades. Gastric ulcer healing is successful with conventional treatments including H2-receptor antagonists, and proton pump inhibitors(PPIs) have been essential for ulcer healing and prevention of complications. Additionally, Helicobacter pylori eradication therapy is effective in reducing ulcer recurrence and leads to physiological changes in the gastric mucosa which affect the ulcer healing process. However, in spite of these advancements, some patients have suf-fered from recurrence or intractability in spite of continuous anti-ulcer therapy. A new concept of the quality of ulcer healing(QOUH) was initiated that considers the reconstruction of the mucosal structure and its function for preventing ulcer recurrence. Although several gastroprotection provided these achievements of the QOUH, which PPI or other acid suppressants did not accomplish, we found that gastroprotection that originated from natural products, such as a newer formulation from either Artemisia or S-allyl cysteine from garlic, were very effective in the QOUH, as well as improving clinical symptoms with fewer side effects. In this review, we will introduce the importance of the QOUH in ulcer healing and the achievements from natural products.

关键词： Quality of ulcer healing Natural products Gastric ulcers Acid suppression S-allyl cysteine Artemisia isopropanol extract

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超声波联合扶正升血方穴位贴敷在肝硬化脾功能亢进患者中的应用

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世界科学技术-中医药现代化 2019年第4期21卷 744-748页

作者：徒康宛朱银芳汤勤俞萍严志涵徐淑凡冯建红无锡市第五人民医院

目的:探讨超声波联合扶正升血方穴位贴敷对肝硬化脾功能亢进患者白细胞、红细胞、血小板的影响及不良反应。方法:将65例入组患者,随机分为两组,对照组予利可君口服,疗程4周;治疗组在对照组治疗的基础上,加用超声波联合扶正升血方穴位贴... 详细信息

目的:探讨超声波联合扶正升血方穴位贴敷对肝硬化脾功能亢进患者白细胞、红细胞、血小板的影响及不良反应。方法:将65例入组患者,随机分为两组,对照组予利可君口服,疗程4周;治疗组在对照组治疗的基础上,加用超声波联合扶正升血方穴位贴敷。两组均检测治疗前后患者白细胞、红细胞、血小板水平,观察症状改善情况。结果:治疗组总有效率达84.37%,对照组总有效率达48.48%,差异具有统计学意义(P <0.05);治疗组治疗前后症状积分有统计学意义(P <0.05),对照组治疗前后症状积分无统计学意义。结论:超声波联合扶正升血方穴位贴敷对肝硬化脾功能亢进具有良好的疗效,无明显不良反应。

关键词：超声波扶正升血方穴位贴敷脾功能亢进

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固态电解质锂镧锆氧(LLZO)的研究进展

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储能科学与技术 2020年第2期9卷 523-537页

作者：姜鹏峰石元盛李康万韩百川颜立全孙洋卢侠中山大学广东广州510006 北京化工大学北京100029

高安全、高能量密度以及长寿命全固态电池被视为下一代最重要的储能技术之一,而开发高性能固态电池的核心之一就是制备性能匹配的固态电解质。石榴石型的Li7La3Zr2O12(LLZO)固态电解质因其高离子电导(室温下约10-3 S/cm)、高电化学稳定... 详细信息

高安全、高能量密度以及长寿命全固态电池被视为下一代最重要的储能技术之一,而开发高性能固态电池的核心之一就是制备性能匹配的固态电解质。石榴石型的Li7La3Zr2O12(LLZO)固态电解质因其高离子电导(室温下约10-3 S/cm)、高电化学稳定性和对正极材料及锂金属负极良好的化学稳定性,自2007年被发现之后,便被认为是颇具前景的一类固态电解质材料。本文系统地综述了LLZO在结构调控、掺杂策略、离子输运机制认识以及界面稳定策略等最新进展;总结了对富锂石榴石结构、快离子输运行为的认识过程;并系统介绍了优化正极/负极与石榴石型固体电解质界面结构,改善界面润湿性的解决思路及LLZO基固态电解质材料构筑固态电池的进展,以期为探索全固态锂离子电池的实际应用提供借鉴。

关键词：富锂石榴石锂镧锆氧离子电导率离子输运固态电池

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