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Intricate Fault Systems in Longmenshan Structural Belt's Northern End: Exploring Structural Evolution and Seismic Rupture Behavior in the Eastern Tibetan Plateau

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Journal of Earth Science 2024年

作者： Hanyu Huang Renqi Lu Dengfa He Jinliang Gao Weikang zhang Lingyu kang State Key Laboratory of Earthquake Dynamics， Institute of Geology China Earthquake Administration State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation， Institute of Sedimentary Geology， Chengdu University of Technology College of Energy Resources， China University of Geosciences PetroChina Research Institute of Petroleum Exploration and Development

The Longmenshan Structural Belt on the eastern edge of the Tibetan Plateau experienced the impactful Mw 7.9 2008 Wenchuan earthquake， causing a 350 km surface rupture. Traditional models attribute this to the Beichuan and Pengguan faults， but our research reveals a complex fault system at the northern end， with inconsistencies in surface rupture， aftershock distribution， and focal mechanisms. We integrates shallow geology， active source seismic reflection， and magnetotelluric profiling to establish a deep structural model for the northern end of the Longmenshan Structural Belt. This area exhibits dominant reverse thrust nappe tectonics， and analyzing the tectonic evolution history provides insights into deformation propagation from the orogenic belt toward the Sichuan Basin. Focal mechanism analysis and relocated aftershock data reveals two distinct types of seismogenic structures in the northern end of the Longmenshan Structural Belt. In the middle to northern segments， the reverse fault type is attributed to reactivated pre-existing faults. Conversely， at the northern end， the strike-slip fault type originates from high-angle co-seismic rupture cutting through pre-existing reverse faults. This study enhances our understanding of fault complexity and seismic mechanisms in the northeastern Longmenshan Structural Belt， providing new insights into regional tectonics.

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Student Academic Performance Predictive Model Based on Dual-stream Deep Network

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计算机科学 2024年第10期51卷 119-128页

作者： XIE Hui zhang Pengyuan DONG Zexiao YANG Huiting kang Huan HE Jiangshan CHEN Xueli Center for Biomedical-photonics and Molecular Imaging Xi’an Key Laboratory of Intelligent Sensing and Regulation of trans-Scale Life InformationSchool of Life Science and TechnologyXidian UniversityXi’an 710126China Engineering Research Center of Molecular and Neuro Imaging Ministry of EducationXi’an 710126China Innovation Center for Advanced Medical Imaging and Intelligent Medicine Guangzhou Institute of TechnologyXidian UniversityGuangzhou 510550China

Blended teaching is one of the essential teaching methods with the development of information *** a learning effect evaluation model is helpful to improve students’academic performance and helps teachers to better implement course ***,a lack of evaluation models for the fusion of temporal and non-temporal behavioral data leads to an unsatisfactory evaluation *** meet the demand for predicting students’academic performance through learning behavior data,this study proposes a learning effect evaluation method that integrates expert perspective indicators to predict academic performance by constructing a dual-stream network that combines temporal behavior data and non-temporal behavior data in the learning *** this paper,firstly,the Delphi method is used to analyze and process the course learning behavior data of students and establish an effective evaluation index system of learning behavior with universality;secondly,the Mann-Whitney U-test and the complex correlation analysis are used to analyze further and validate the evaluation indexes;and lastly,a dual-stream information fusion model,which combines temporal and non-temporal features,is *** learning effect evaluation model is built,and the results of the mean absolute error(MAE)and root mean square error(RMSE)indexes are 4.16 and 5.29,*** study indicates that combining expert perspectives for evaluation index selection and further fusing temporal and non-temporal behavioral features that for learning effect evaluation and prediction is rationality,accuracy,and effectiveness,which provides a powerful help for the practical application of learning effect evaluation and prediction.

关键词： Blended teaching Expert perspective indicators Two-stream information fusion model

Identification of candidate genes for early-maturity traits by combining BSA-seq and QTL mapping in upland cotton(Gossypium hirsutum L.)

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Journal of Integrative Agriculture 2024年第10期23卷 3472-3486页

作者： Liang Ma Tingli Hu Meng kang Xiaokang Fu Pengyun Chen Fei Wei Hongliang Jian Xiaoyan Lü Meng zhang Yonglin Yang State Key Laboratory of Cotton Bio-breeding and Integrated Utilization/Institute of Cotton Research Chinese Academy ofAgricultural SciencesAnyang 455000China School of Agriculture Henan Institute of Science and TechnologyXinxiang 453003China Shihezi Academy of Agricultural Sciences Shihezi 832099China

Cotton breeding for the development of early-maturing varieties is an effective way to improve multiple cropping indexes and alleviate the conflict between grains and cotton in the cultivated fields in *** the present study,we aimed to identify upland cotton quantitative trait loci(QTLs)and candidate genes related to early-maturity traits,including whole growth period(WGP),flowering timing(FT),node of the first fruiting branch(NFFB),height of the node of the first fruiting branch(HNFFB),and plant height(PH).An early-maturing variety,CCRI50,and a latematuring variety,Guoxinmian 11,were crossed to obtain biparental *** populations were used to map QTLs for the early-maturity traits for two years(2020 and 2021).With BSA-seq analysis based on the data of population 2020,the candidate regions related to early maturity were found to be located on chromosome *** then developed 22 polymorphic insertions or deletions(InDel)markers to further narrow down the candidate regions,resulting in the detection of five and four QTLs in the 2020 and 2021 populations,*** to the results of QTL mapping,two candidate regions(InDel_G286-InDel_G144 and InDel_G24-InDel_G43)were *** these regions,three genes(GH_D03G0451,GH_D03G0649,and GH_D03G1180)have nonsynonymous mutations in their exons and one gene(GH_D03G0450)has SNP variations in the upstream sequence between CCRI50 and Guoxinmian *** four genes also showed dominant expression in the floral *** expression levels of GH_D03G0451,GH_D03G0649 and GH_D03G1180 were significantly higher in CCRI50 than in Guoxinmian 11 during the bud differentiation stages,while GH_D03G0450 showed the opposite *** functional verification of GH_D03G0451 indicated that the GH_D03G0451-silenced plants showed a delay in the flowering *** results suggest that these are the candidate genes for cotton early maturity,and they may be used for breeding early-maturity cotton varieties.

关键词： cotton genomics early-maturity traits BSA-seq QTL mapping molecular breeding

A single-nucleus transcriptomic atlas of primate liver aging uncovers the pro-senescence role of SREBP2 in hepatocytes

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Protein & Cell 2024年第2期15卷 98-120页

作者： Shanshan Yang Chengyu Liu Mengmeng Jiang Xiaoqian Liu Lingling Geng Yiyuan zhang Shuhui Sun kang Wang jian Yin Shuai Ma Si Wang Juan Carlos Izpisua Belmonte Weiqi zhang Jing Qu Guang-Hui Liu Advanced Innovation Center for Human Brain Protection and National Clinical Research Center for Geriatric Disorders Xuanwu Hospital Capital Medical UniversityBeijing 100053China State Key Laboratory of Membrane Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China Aging Translational Medicine Center International Center for Aging and CancerBeijing Municipal Geriatric Medical Research CenterXuanwu HospitalCapital Medical UniversityBeijing 100053China State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China CAS Key Laboratory of Genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of Sciences and China National Center for BioinformationBeijing 100101China Xuanwu Hospital Capital Medical University Beijing 100053China University of Chinese Academy of Sciences Beijing 100049China Institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijing 100101China Beijing Institute for Stem Cell and Regenerative Medicine Beijing 100101China Aging Biomarker Consortium Beijing 100101China Altos Labs Inc.San DiegoCA 94022USA

Aging increases the risk ofliver diseases and systemic susceptibility to aging-related ***,cell type-specific changes and the underlying mechanism of liver aging in higher vertebrates remain incompletely ***,we constructed the first single-nucleus transcriptomic landscape of primate liver aging,in which we resolved cell type-specific gene expression fluctuation in hepatocytes across three liver zonations and detected aberrant cell-cell interactions between hepatocytes and niche *** in-depth dissection of this rich dataset,we identifed impaired lipid metabolism and upregulation of chronic inflammation-related genes prominently associated with declined liver functions during *** particular,hyperactivated sterol regulatory element-binding protein(SREBP)signaling was a hallmark of the aged liver,and consequently,forced activation of SREBP2 in human primary hepatocytes recapitulated in vivo aging phenotypes,manifesting as impaired detoxification and accelerated cellular *** study expands our knowledge of primate liver aging and informs the development of diagnostics and therapeutic interventions for liver aging and associated diseases.

关键词： single-nucleus RNA sequencing liver hepatocytes aging senescence SREBP2

基于多窗口识别的多波长光信号峰值实时检测系统

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红外与激光工程 2024年第5期53卷 198-207页

作者：张康姜海明谢康广东工业大学机电工程学院精密电子制造技术与装备国家重点实验室广东广州510006

波分复用(Wavelength Division Multiplexing,WDM)作为光纤通信系统的核心技术之一,为多个波长光信号的复用和传输提供了强有力的解决方案,对复用光信号的解复用和识别是WDM系统需解决的重要问题之一。文中研制了一种针对多波长光信号... 详细信息

波分复用(Wavelength Division Multiplexing,WDM)作为光纤通信系统的核心技术之一,为多个波长光信号的复用和传输提供了强有力的解决方案,对复用光信号的解复用和识别是WDM系统需解决的重要问题之一。文中研制了一种针对多波长光信号峰值的实时检测系统,用于实时检测多波长光信号的峰值功率。首先,设计并研制了光纤法布里-珀罗可调谐滤波器(FFP-TF)的驱动控制器和微弱光信号探测器,分别控制FFP-TF的驱动电压使其滤出特定波长的光信号和对滤出光信号的功率进行实时探测;其次,对于光电探测器中实时探测的光信号功率,设计了一种基于多窗口识别的峰值检测方法,使用三个针对波形不同位置的数据筛选窗口,根据实时检测数据来识别波形的变化趋势从而得到峰值强度与位置,进而计算出对应的光信号峰值强度。实验结果显示,所研制的实时检测系统实现了对多波长光信号的实时检测以及峰值的识别,光信号检测强度范围为0~-60 dBm,识别速度较快,对于准周期或周期的多波长光信号的识别具有良好的识别效果。

关键词：光纤通信信号峰值检测系统光信号探测法布里-珀罗可调谐滤波器波分复用技术

High recorded color rendering performance of single-structured Ce,Mn:Y_(3)(Al,Sc)_(2)Al_(3)O_(12)phosphor ceramics for high-power white LEDs/LDs

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Journal of Advanced Ceramics 2024年第6期13卷 810-820页

作者： Xuanchu Liu Congcong Yang Yanbin Li Chang Min Jian kang Tianyuan Zhou Chunming Zhou Chaofan Shi Cen Shao Bingheng Sun Wieslaw Strek Hao Chen Le zhang Jiangsu Key Laboratory of Advanced Laser Materials and Devices School of Physics and Electronics EngineeringJiangsu Normal UniversityXuzhou 221116China Jiangsu Xiyi Advanced Materials Research Institute of Industrial Technology Xuzhou 221400China Xuzhou EAGLED Technology Co. Ltd.Xuzhou 221116China Xuzhou kangna Advanced Materials Technology Co. Ltd.Xuzhou 221116China Shanghai Institute of Optics Fine Mechanics Chinese Academy of SciencesShanghai 201800China Institute of Low Temperature and Structure Research Polish Academy of SciencesWroclaw 50-422Poland State Key Laboratory of Crystal Materials Shandong UniversityJinan 250100China

Achieving a high color rendering index(CRI)and luminous stability in single-structured Ce:Y_(3)Al_(5)O_(12)(Ce:YAG)phosphor ceramics(PCs)is crucial for high-power white light-emitting diodes or laser diodes(LEDs/LDs).However,cyan valleys and insufficient amounts of the red component in the Ce:YAG emission spectra significantly limit their real *** this work,a series of Ce,Mn:Y_(3)(Al,Sc)_(2)Al_(3)O_(12)(Ce,Mn:YSAG)PCs were fabricated by vacuum sintering,and efficient spectral regulation was realized for full-color *** cyan valley was filled by the blueshifted emission peak of Ce^(3+)via Sc^(3+)*** orange‒red emission at approximately 580 nm was effectively supplemented via Mn^(2+)*** particular,CRI of Ce,Mn:YSAG increased from 56.4 to 85.8,a 52%increase compared with that of Ce:YAG under high-power LED excitation,and the operating temperature was stable at approximately 50℃for long working ***,CRI of 80.9 could still be obtained for PC-based white *** results indicated that Ce,Mn:YSAG PC,which has excellent CRI and luminous stability,is an extremely promising color convertor for high-power white LEDs/LDs.

关键词： color rendering index(CRI) color converter Ce:Y_(3)Al_(5)O_(12)(Ce:YAG)phosphor ceramics(PCs) high-power white light-emitting diodes or laser diodes(LEDs/LDs) luminous stability

Single cell analysis unveils B cell-dominated immune subtypes in HNSCC for enhanced prognostic and therapeutic stratification

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International Journal of Oral Science 2024年第3期16卷 448-459页

作者： kang Li Caihua zhang Ruoxing Zhou Maosheng Cheng Rongsong Ling Gan Xiong Jieyi Ma Yan Zhu Shuang Chen Jie Chen Demeng Chen Liang Peng State Key Laboratory of Oncology in South China Department of Oral and Maxillofacial SurgeryInstitute of Precision MedicineCenter for Translational MedicineThe First Affiliated Hospital of Sun Yat-sen UniversityGuangzhouChina Institute for Advanced Study Shenzhen UniversityShenzhenChina Hospital of Stomatology Guangdong Provincial Key Laboratory of StomatologyGuanghua School of StomatologySun Yat-Sen UniversityGuangzhouChina Senior Department of Oncology The Fifth Medical Center of PLA General HospitalBeijingChina

Head and neck squamous cell carcinoma(HNSCC)is characterized by high recurrence or distant metastases rate and the prognosis is *** is mounting evidence that tumor-infiltrating B cells(TIL-Bs)have a crucial,synergistic role in tumor ***,little is known about the role TIL-Bs play in immune microenvironment and the way TIL-Bs affect the outcome of immune checkpoint *** single-cell RNA sequencing(scRNA-seq)data from the Gene Expression Omnibus(GEO)database,the study identified distinct gene expression patterns in *** samples were categorized into TIL-Bs inhibition and TIL-Bs activation groups using unsupervised *** classification was further validated with TCGA HNSCC data,correlating with patient prognosis,immune cell infiltration,and response to *** found that the B cells activation group exhibited a better prognosis,higher immune cell infiltration,and distinct immune checkpoint levels,including elevated PD-L1.A prognostic model was also developed and validated,highlighting four genes as potential biomarkers for predicting survival outcomes in HNSCC ***,this study provides a foundational approach for B cells-based tumor classification in HNSCC,offering insights into targeted treatment and immunotherapy strategies.

关键词： prognosis elevated offering

Milestone progress of the HEPS booster commissioning

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Nuclear Science and Techniques 2024年第1期35卷 170-177页

作者： Yue-Mei Peng Jian-She Cao Jin-Hui Chen Hai-Yi Dong Ping He Yi Jiao Ling kang Wen kang Jian Li Jing-Yi Li Guo-Ping Lin Fang Liu Feng-Li Long Cai Meng Xin Qi Hua-Min Qu Yan-Feng Sui Sheng Wang Gang Xu Qiang Ye Jing zhang Pei zhang Wei-Min Pan Key Laboratory of Particle Acceleration Physics and Technology Institute of High Energy PhysicsChinese Academy of Sciences19B Yuquan RoadShijingshan DistrictBeijing 100049China University of the Chinese Academy of Sciences 19A Yuquan RoadShijingshan DistrictBeijing 100049China

The high-energy photon source(HEPS)is the first fourth-generation synchrotron light source facility in *** HEPS injector consists of a linear accelerator(Linac)and a full energy *** booster captures the electron beam from the Linac and increases its energy to the value required for the storage *** full-energy beam could be injected to the storage ring directly or after“high-energy accumulation.”On November 17,2023,the key booster parameters successfully reached their corresponding target *** milestone results were achieved based on numerous contributions,including nearly a decade of physical design,years of equipment development and installation,and months of beam *** measured at the extraction energy of 6 GeV,the averaged beam current and emittance reached 8.57 mA with 5 bunches and 30.37 nm rad with a single-bunch charge of 5.58 nC,compared with the corresponding target values of 6.6 mA and 35 nm rad,*** paper presents the physical design,equipment development,installation,and commissioning process of the HEPS booster.

关键词： High energy photon source Booster Beam commissioning

Five-year analysis of isolated pathogens and antibiotic resistance of ocular infections from two large tertiary comprehensive hospitals in east China

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International Journal of Ophthalmology(English edition) 2024年第9期17卷 1707-1716页

作者： Pan-Pan Li Li Li Jun-Fang zhang Bai Qin Li-Hua kang Min Ji Huai-Jin Guan Suzhou Medical College of Soochow University Suzhou 215123Jiangsu ProvinceChina Department of Ophthalmology Affiliated Hospital of Nantong UniversityNantong 226001Jiangsu ProvinceChina Department of Clinical Laboratory Nantong City No.1 People’s Hospital and Second Affiliated Hospital of Nantong UniversityNantong 226001Jiangsu ProvinceChina

AIM:To analyze the spectrum of isolated pathogens and antibiotic resistance for ocular infections within 5y at two tertiary hospitals in east ***:Ocular specimen data were collected from January 2019 to October *** pathogen spectrum and positive culture rate for different infection location,such as keratitis,endophthalmitis,and periocular infections,along with antibiotic resistance were ***:We included 2727 specimens,including 827(30.33%)positive cultures.A total of 871 strains were isolated,530(60.85%)bacterial and 341(39.15%)fungal strains were ***-positive cocci(GPC)were the most common ocular *** most common bacterial isolates were Staphylococcus epidermidis(25.03%),Staphylococcus aureus(7.46%),Streptococcus pneumoniae(4.59%),Corynebacterium macginleyi(3.44%),and Pseudomonas aeruginosa(3.33%).The most common fungal genera were Fusarium spp.(12.74%),Aspergillus spp.(6.54%),and Scedosporium spp.(5.74%).Staphylococcus epidermidis strains showed more than 50%resistance to *** pneumoniae and Corynebacterium macginleyi showed more than 90%resistance to *** percentage of bacteria showing multidrug resistance(MDR)significantly decreased(χ^(2)=17.44,P=0.002).CONCLUSION:GPC are the most common ocular *** macginleyi,as the fourth common bacterium,may currently be the local microbiological feature of east *** *** the most common *** than 50%of the GPC are resistant to fluoroquinolones,penicillins,and ***,the proportion of MDR strains has been reduced over time.

关键词： ocular infections bacteria fungus antibiotic resistance multidrug resistance