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High-accuracy calibration for multi-laser powder bed fusion via in situ detection and parameter identification

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Advances in Manufacturing 2022年第4期10卷 556-570页

作者： Qi Zhong Xiao-Yong Tian Xiao-kang huang Zhi-Qiang Tong Yi Cao Di-Chen Li State Key Laboratory of Manufacturing Systems Engineering Xi’an Jiaotong UniversityXi’an710049People’s Republic of China

Multi-laser powder bed fusion(ML-PBF)adopts multiple laser-scanner systems to increase the build envelope and build speed,but its calibration is an iterative and time-consuming *** particular,multiple large-scale scan fields have a complex distortion in the overlap area,challenging the calibration *** this study,owing to the enormous workload and alignment problems in the calibration of multiple scan fields,a novel calibration system is designed in this study to realize in situ auto-detection of numerous laser spots in the build chamber to ensure high efficiency and ***,because the detectable area could not cover the entire build area and the detection data still contained errors,a virtual laser-scanner system was established by identifying the assembly defects and galvo nonlinearities of the ML-PBF system from the detection data,which served as the system's controller to improve calibration *** multi-field alignment error was less than 0.012%,which could avoid the intersection and separation of scan paths in multi-laser scanning and therefore meet the requirements for high-precision ***,the reliability of the method was verified theoretically using principal component analysis.

关键词： Powder bed fusion Multi-laser technology Galvo calibration Assembly defects System identification

A generalized framework for AMOVA with multiple hierarchies and ploidies

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Integrative Zoology 2021年第1期16卷 33-52页

作者： kang huang Tiantian WANG Derek W.DUNN Pei ZHANG Hongjuan SUN Baoguo LI Shaanxi Key Laboratory for Animal Conservation College of Life SciencesNorthwest UniversityXi’anChina Department of Forest and Conservation Sciences University of British ColumbiaVancouverCanada Center for Excellence in Animal Evolution and Genetics Chinese Academy of SciencesKunmingChina

The analysis of molecular variance(AMOVA)is a widely used statistical method in population genetics and molec-ular *** classic framework of AMOVA only supports haploid and diploid data,in which the number of hierarchies ranges from two to *** practice,natural populations can be classified into more hierarchies,and polyploidy is frequently observed in extant *** ploidy level may even vary within the same species,and/or within the same *** generalized the framework of AMOVA such that it can be used for any number of hierarchies and any level of *** on this framework,we present four methods to account for data that are multilocus genotypic and allelic phenotypic(with unknown allele dosage).We use simulated datasets and an empirical dataset to evaluate the performance of our *** make freely available our methods in a new software package,polygene,which is freely available at https://***/huangkang1987/polygene.

关键词： analysis of molecular variance hierarchy maximum-likelihood estimation method-of-moment estimation polyploidy

A combined geophysical and lithological study on eruptive history and Quaternary lacustrine stratigraphy of a maar in Leizhou Peninsula, China

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Journal of Palaeogeography 2021年第1期10卷 98-111页

作者： Cong Chen Zhuo Zheng Li-Feng Zeng Fan Xiao Li-Ping Tian kang-You huang Guangdong Provincial Key Lab of Geodynamics and Geohazards School of Earth Sciences and EngineeringSun Yat-sen UniversityGuangzhou 510275Guangdong ProvinceChina Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai 519082Guangdong ProvinceChina

As the second common type of volcanic vent on Earth, maar-diatreme volcanoes and their post-eruptive lacustrine sediments are a main focus of volcanology, palaeolimnology, palaeoclimatology and palaeontology. A number of maar-type volcanoes have been found in Leizhou Peninsula, South China, but little is known about their eruption processes and detailed stratigraphy of the post-eruptive sediments. We present a combined geophysical and geological analysis to study the eruptive history and post-eruptive sediment stratigraphy of a large maar, the elliptical(1.8 × 3.0 km^(2)) Jiudouyang(JDY) maar. The lacustrine stratigraphy revealed by drilling cores shows that the JDY maar lake has three major stages of evolution:(i) deep-lake sedimentary environment characterized by high autochthonous diatom productivity;(ii) shallow lake to swamp with very low water levels, characterized by a high total organic carbon(TOC) and abundant wood fragments;and,(iii) intermittent shallow lake and alluvial deposits composed of clay minerals and sand. The electrical resistivity tomography(ERT) values and lithological features are highly consistent, which clearly reveal the presence of ca. 50 m thick lacustrine sediments, directly underlain by a ca. 70 m thick basaltic lava rather than diatreme breccia in the crater. This infill sequence implies an alternation of eruption style from phreatomagmatic to Strombolian and/or lava flow, due to high magma flux and ascent rate of the Hainan Plume during the middle Pleistocene. The ERT data also reveal the initial phreatomagmatic crater floor at ca. 120 m depth. The initial crater had a large diameter/depth ratio(ca. 17), with an elongated shape(major axis to minor axis = 0.6), implying possible lateral vent migration during the eruption. A significant erosion under tropical weathering condition during the last few hundred thousand years, accounted for the large size of the maar crater. The study provides insights into the eruptive history and post-er

关键词： Maar crater Eruptive history Infill sequence Lake evolution Lacustrine stratigraphy Leizhou Peninsula

Chiral Recognition and Photoreaction of β-Amino Acids with Iridium(III)Complexes

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Chinese Journal of Chemistry 2022年第24期40卷 2909-2918页

作者： Ming-Feng Xiong Hai-Yun Zhou Xiao-kang huang Jing-Yan Fan Bao-Hui Ye MOE Key Laboratory of Bioinorganic and Synthetic Chemistry School of ChemistrySun Yat-sen UniversityGuangzhouGuangdong510275 China Instrumental Analysis and Research Center Sun Yat-sen UniversityGuangzhouGuangdong510275 China

β-Amino acids(AAs),homologs ofα-AAs,are important building blocks of biological ***,chiral recognitions ofβ-AAs with Ir(III)complexes are reported,in favor of formation of the thermodynamically stableΛ-[Ir(pq)_(2)(D-β-AAs)]andΔ-[Ir(pq)_(2)(L-β-AAs)](pq is 2-phenylquinoline)*** photoreactions of[Ir(pq)_(2)(β-AA)]complexes are observed in an EtOH solution in the presence of O_(2) at room *** primaryβ-AAs complexes,such as rac-[Ir(pq)_(2)(β-ala)](β-ala isβ-alanine),Δ-[Ir(pq)_(2)(D-β-ma)]andΛ-[Ir(pq)_(2)(D-β-ma)](β-ma isβ-methylalanine),Δ-[Ir(pq)_(2)(D-β-pa)]andΛ-[Ir(pq)_(2)(D-β-pa)](β-pa isβ-phenylalanine),and rac-[Ir(pq)_(2)(β-dma)](β-dma is 3,3-dimethyl-β-alanine),are interligand C—N cross-coupling in situ between pq andβ-AAs *** secondaryβ-AA complexesΔ-[Ir(pq)_(2)(L-β-pro)]andΛ-[Ir(pq)_(2)(L-β-pro)](β-pro isβ-proline,2-(pyrrolidin-2-yl)acetic acid)are dehydrogenatively oxidized into imino acid complexesΔ-[Ir(pq)_(2)(L-β-pro-2H^(β)’)]andΛ-[Ir(pq)_(2)(L-β-pro-2H^(β)’)](L-β-pro-2H^(β)’=2-(3,4-dihydro-2H-pyrrol-2-yl)acetic acid),***,the dehydrogenative reaction inΔ-[Ir(pq)_(2)(L-β-pro)]diastereomer is regioselective depending on the reaction temperature,affordingΔ-[Ir(pq)_(2)(L-β-pro-2H^(β)’)]andΔ-[Ir(pq)_(2)(L-β-pro-2H^(β))](β-pro-2H^(β)=2-(3,4-dihydro-2H-pyrrol-5-yl)acetic acid)at low *** chiral recognitions and photoreactions of Ir(III)-β-AAs complexes are much different from the previous observations in Ir(III)-α-AAs complexes.

关键词： Photooxidation Chiral recognition Regioselectivity Enantioselectivity β-Amino acid

An Easily Compatible Eye-tracking System for Freely-moving Small Animals

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Neuroscience Bulletin 2022年第6期38卷 661-676页

作者： kang huang Qin Yang Yaning Han Yulin Zhang Zhiyi Wang Liping Wang Pengfei Wei Shenzhen Key Lab of Neuropsychiatric Modulation and Collaborative Innovation Center for Brain Science Guang-dong Provincial Key Laboratory of Brain Connectome and BehaviorCAS Center for Excellence in Brain Science and Intelligence TechnologyBrain Cognition and Brain Disease InstituteShenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research InstitutionsShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China University of Chinese Academy of Seiences Bejing 100049China Harbin Institute of Technology Shenzhen Shenzhen 518055.China

Measuring eye movement is a fundamental approach in cognitive science as it provides a variety of insightful parameters that reflect brain states such as visual attention and *** eye-tracking with multimodal neural recordings or manipulation techniques is beneficial for understanding the neural substrates of cognitive *** commercially-available and custom-built systems have been widely applied to awake,head-fixed small ***,the existing eyetracking systems used in freely-moving animals are still limited in terms of their compatibility with other devices and of the algorithm used to detect eye ***,we report a novel system that integrates a general-purpose,easily compatible eye-tracking hardware with a robust eye feature-detection *** ultra-light hardware and a detachable design,the system allows for more implants to be added to the animal's exposed head and has a precise synchronization module to coordinate with other neural ***,we systematically compared the performance of existing commonly-used pupil-detection approaches,and demonstrated that the proposed adaptive pupil feature-detection algorithm allows the analysis of more complex and dynamic eye-tracking data in freemoving *** eye-tracking and electroencephalogram recordings,as well as algorithm validation under five noise conditions,suggested that our system is flexibly adaptable and can be combined with a wide range of neural manipulation and recording technologies.

关键词： Eye-tracking Freely-moving Head-mounted device Pupil detection Adaptive Kalman filter

Influence of Transportation Accessibility on Urban-rural Income Disparity and Its Spatial Heterogeneity

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Chinese Geographical Science 2024年第3期34卷 453-467页

作者： huang Xiaoyan kang Chenchen YIN Chun TANG Junqing Northwest Land and Resources Research Center Global Regional and Urban Research InstituteShaanxi Normal UniversityXi’an 710119China School of Resource and Environmental Sciences Wuhan UniversityWuhan 430079China International Institute of Spatial Lifecourse Health(ISLE) Wuhan UniversityWuhan 430079China School of Urban Planning and Design Shenzhen Graduate SchoolPeking UniversityShenzhen 518055China Key Laboratory of Earth Surface System and Human-Earth Relations of Ministry of Natural Resources of China Shenzhen Graduate SchoolPeking UniversityShenzhen 518055China

Transportation accessibility has been treated as an important means of reducing the urban-rural income ***,only a few studies have examined the effects of different types of transportation accessibility on urban-rural income disparity and their spatial *** on data from 285 prefecture-level(and above)Chinese cities in 2000,2005,2010,2015,and 2020,this study uses spatial econometric models to examine how highway accessibility and railway accessibility influence the urban-rural income disparity and to identify their spatial *** result reveals that highway accessibility and railway accessibility have‘coreperiphery’ring-like circle *** urban-rural income disparity exhibits strong spatial clustering *** highway accessibility and railway accessibility are negatively associated with urban-rural income disparity,and the former having a greater effect ***,there is a substitution effect between highway accessibility and railway accessibility in the whole ***,these associations differ in geographic *** the central region,highway accessibility is more important in reducing the urban-rural income disparity,but its effect is weakened with the increase of railway *** the western region,railway accessibility has a larger effect on narrowing the urban-rural income disparity,and this effect is strengthened by the increase of highway *** conclude that improving transportation accessibility is conducive to reducing the urban-rural income disparity but its effect is spatial *** and railways should be developed in a coordinated manner to promote an integrated transport network system.

关键词： transport accessibility income gap regional divergence spatial heterogeneity urban and rural areas China

A bounding surface visco-plasticity model considering generalized spacing ratio of soils

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第5期16卷 1832-1846页

作者： Xiaosen kang Hongjian Liao Qiangbing huang Jianbing Peng Department of Geological Engineering Chang’an UniversityXi’an710054China Department of Civil Engineering Xi’an Jiaotong UniversityXi’an710049China

The non-unique critical state of soils with time-dependent behaviors is a significant issue in geotechnical engineering ***,previous bounding surface plasticity models cannot predict accurately the non-unique critical state of soils,because the distance between the compression line and critical state line charged by strain-rate effect is basically *** fill this gap,a generalized spacing ratio of soils is defined in the elasto-viscoplastic framework,and a bounding surface visco-plasticity model is formulated and verified,which can consider the generalized spacing ***,the generalized spacing ratio of soils reflects the distance between the compression line and the critical state line of soils with time-dependent ***,the generalized spacing ratio is introduced into an improved anisotropic bounding surface.A new expression of the visco-plastic multiplier is derived by solving the consistency equation of an anisotropic bounding *** the expression,a strain rate index is proposed to account for the strain-rate effect on visco-plastic strain increment,and a visco-plastic hardening modulus is derived to predict the visco-plastic response of soils in overconsolidation *** model is then verified through constant strain rate tests and creep ***,it can capture the non-unique critical states of soils with time-dependent behaviors due to the generalized spacing ratio and the creep rupture of soils due to the visco-plastic multiplier that considers the stress ratio and visco-plastic strain rate.

关键词： Soil Constitutive model Visco-plastic behavior Strain rate Creep Anisotropic

Exploring the regulatory mechanism of tRNA-derived fragments 36 in acute pancreatitis based on small RNA sequencing and experiments

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World Journal of Gastroenterology 2023年第30期29卷 4642-4656页

作者： Xi-Rui Fan Yun huang Yu Su Si-Jin Chen Yu-Lu Zhang Wei-kang huang Hui Wang Department of Gastroenterology The Affiliated Yan’an Hospital of Kunming Medical UniversityKunming 650051Yunnan ProvinceChina Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province Yan’an Hospital of KunmingKunming 650051Yunnan ProvinceChina

BACKGROUND Acute pancreatitis(AP)is a disease featuring acute inflammation of the pancreas and histological destruction of acinar *** 20%of AP patients progress to moderately severe or severe pancreatitis,with a case fatality rate of up to 30%.However,a single indicator that can serve as the gold standard for prognostic prediction has not been ***,gaining deeper insights into the underlying mechanism of AP progression and the evolution of the disease and exploring effective biomarkers are important for early diagnosis,progression evaluation,and precise treatment of *** To determine the regulatory mechanisms of tRNA-derived fragments(tRFs)in AP based on small RNA sequencing and *** Small RNA sequencing and functional enrichment analyses were performed to identify key tRFs and the potential mechanisms in *** transcription quantitative polymerase chain reaction(RT-qPCR)was conducted to determine tRF *** cell and mouse models were created to investigate the role of tRF36 in AP ***,amylase,and cytokine levels were assayed to examine AP *** expression,reactive oxygen species,malondialdehyde,and ferric ion levels were assayed to evaluate cellular *** pull down assays and methylated RNA immunoprecipitation were performed to explore the molecular *** RT-qPCR results showed that tRF36 was significantly upregulated in the serum of AP patients,compared to healthy *** enrichment analysis indicated that target genes of tRF36 were involved in ferroptosisrelated pathways,including the Hippo signaling pathway and ion ***,the occurrence of pancreatic cell ferroptosis was detected in AP cells and mouse *** results of interference experiments and AP cell models suggested that tRF-36 could promote AP progression through the regulation of ***,ferroptosis gene microarray,database prediction,and immunopreci

关键词： Acute pancreatitis tRNA-derived fragments tRNA-derived fragments 36 Mouse models Ferroptosis Reverse transcription quantitative polymerase chain reaction

Synthesis of Cerium-containing Polymethylphenyl Silicone and Its Antioxidant Effect on Fluorosilicone Rubber

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Chinese Journal of Polymer Science 2019年第8期37卷 783-789页

作者： Yong Guan Jian Hu Yong-kang huang Yang You Huan-Yao Zhang An-Na Zheng Xiang Xu Da-Fu Wei Key Laboratory for Ultrafine Materials of Ministry of Education School of Materials Science and Engineering East China University of Science and Technology Shanghai 200237 China Key Laboratory for Specially Functional Polymeric Materials and Related Technology of the Ministry of Education School of Materials Science and Engineering East China University of Science and Technology Shanghai 200237 China

As an essential elastomer used in edge technologies, fluorosilicone rubber(FSR) suffers serious oxidative ageing problem when serving at high temperature. Cerium oxide is generally used as an antioxidant additive but remains unsatisfactory. In order to obtain better antioxidant effect on improving the thermal stability of FSR, a kind of cerium-containing polymethylphenyl silicone(PSI-Ce) was synthesized and the structure was verified by Fourier-transform infrared spectroscopy(FTIR) and proton nuclear magnetic resonance(1HNMR). Due to the homogeneous dispersion on molecular scale, PSI-Ce imposed much better antioxidant effect than the commercial CeO2 did, no matter from isothermal degradation at 320 ℃ or thermal-oxidative ageing test at 230 ℃. In particular, after ageing for 72 h,FSR/PSI-Ce(2 phr) maintained 82% of tensile strength and 63% of elongation at break, in comparison to the corresponding values of 48%and 42% for FSR/CeO2(2 phr). Moreover, 2 phr PSI-Ce was equivalent to 0.046 phr CeO2 according to cerium element conservation.

关键词： Polymethylphenyl silicone Cerium Fluorosilicone rubber Thermal stability